Browsing by Author "A.N. Pandey"

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Intracellular levels of hydrogen peroxide and nitric oxide in oocytes at various stages of meiotic cell cycle and apoptosis
(2009) Anima Tripathi; Sabana Khatun; A.N. Pandey; S.K. Mishra; Radha Chaube; T.G. Shrivastav; S.K. Chaube
The objective was to find out the functional roles of hydrogen peroxide (H2O2) and nitric oxide (NO) during various stages of meiotic cell cycle and apoptosis in rat oocytes. For this purpose, 30 oocytes from each stage such as diplotene, metaphase-I (M-I), metaphase-II (M-II) and apoptosis were collected and intracellular H2O2, total nitrite level and inducible nitric oxide synthase (iNOS) expression were analysed. This study demonstrated that generation of a tonic level of H2O2 induces meiotic resumption in diplotene-arrested oocytes and further increase may lead to apoptosis. Conversely, reduction in iNOS expression and total nitrite level are associated with meiotic resumption in diplotene-arrested oocytes, but induce apoptosis in aged oocytes. These results suggest that generation of a tonic level of H2 O2, reduced iNOS expression and total nitrite level are associated with meiotic resumption, while more generation of H2O2 and sustained reduced total nitrite level are linked with oocyte apoptosis in rat.
Mean Amplitudes of Vibration for Tetrahedral Molecules and Ions
(1974) D.K. Sharma; A.N. Pandey; A.K. Dublish; S.N. Rai
Mean amplitudes of vibration for 38 tetrahalides and 15 tetraoxides have been computed at temperatures T = 0 °K, T= 298.15 °K and T=500 °K employing most recent vibralional data. Müller's method has been followed in solving the two dimensional Cyvin's secular determinant. The results have been briefly discussed. © 1974, Walter de Gruyter. All rights reserved.