Browsing by Author "Abdullah R. Alzahrani"

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A comprehensive review on phytochemicals as potential therapeutic agents for stress-induced gastric ulcer
(Springer, 2024) Naiyer Shahzad; Ibrahim Abdel Aziz Ibrahim; Abdullah R. Alzahrani; Saeed S. Al-Ghamdi; Ibrahim Mufadhi M. Alanazi; Md. Parwez Ahmad; Ambrish Kumar Singh; Mohammed Ayad Alruqi; Imran Shahid; Asif Equbal; Mohd Fahami Nur Azlina
Gastric ulcers are the most common chronic gastrointestinal tract disorders, marked by an inflamed break of the mucus membrane covering the alimentary tract. According to recent research, stress-induced ulcers are widespread in our society. A stress ulcer is a mucosal defect that may become complicated due to upper gastrointestinal tract bleeding. The underlying cause of this condition is pH. Physiological stress leads to severe sickness by triggering the excessive secretion of peptic juices or gastric acid. There is a never-ending quest for safe and affordable medication for this disorder. Nature offers many medicinal plants that can be used to treat a wide range of human ailments. Due to their relatively harmless and comparatively free of harmful effects, health-promoting features, pharmacological practices, and affordability to common people to regulate various diseases, medicinal plants, and herbal preparations are gaining a lot of interest in scientific communities these days. Many studies have recently been performed to classify extracts and their constituents that may have a therapeutic effect on peptic ulcers. Therefore, this review aims to address the molecular mechanisms and pharmacological effects of various phytochemicals related to stress-induced gastric ulcers. Combining phytochemical constituents with modern drugs and treatment methods can lead to the development of therapeutic drugs for gastric ulcers. Gastric ulcers and other related diseases may be treated permanently with this approach. © The Author(s) 2024.
A Review on Traditional Anti-ulcer Medicinal Plants
(Bentham Science Publishers, 2023) Ambrish K. Singh; Priyamvada Arun; Jyoti Shukla; Ajay Kumar; Manmath K. Nandi; Zainularifeen Abduljaleel; Saeed S. Al-Ghamdi; Abdullah R. Alzahrani; Naiyer Shahzad
Traditional remedies have been used for generations to treat and maintain people's health and indigenous medicinal plants are an important part of this system, which, unlike western medicine, provide cures for practically all illnesses with no side effects. Ulcer is a chronic ailment that affects most of the world's population and has no absolute cure. An ulcer is the erosion of mucous lining in the gastrointestinal tract due to over secretion of HCl in the stomach, leading to inflammation and soreness. Consumption of highly spicy meals, an obese lifestyle, an unplanned diet, the use of excessive nonsteroidal anti-inflammatory medicines, smoking, stress, an irregular sleep cycle, and regular alcohol consumption are all possible causes of ulcers. Ayurvedic and traditional medicine practitioners employ a variety of indigenous medicinal plants to cure ulcers. This review covers a wide variety of medicinal plants that may work as anti-ulcer and deserve more investigation. © 2023 Bentham Science Publishers.