Browsing by Author "Anil Kumar Yadav"

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Autophagy in hypoxic ovary
(Birkhauser Verlag AG, 2019) Anil Kumar Yadav; Pramod K. Yadav; Govind R. Chaudhary; Meenakshi Tiwari; Anumegha Gupta; Alka Sharma; Ashutosh N. Pandey; Ajai K. Pandey; Shail K. Chaube
Oxygen deprivation affects human health by modulating system as well as cellular physiology. Hypoxia generates reactive oxygen species (ROS), causes oxidative stress and affects female reproductive health by altering ovarian as well as oocyte physiology in mammals. Hypoxic conditions lead to several degenerative changes by inducing various cell death pathways like autophagy, apoptosis and necrosis in the follicle of mammalian ovary. The encircling somatic cell death interrupts supply of nutrients to the oocyte and nutrient deprivation may result in the generation of ROS. Increased level of ROS could induce granulosa cells as well as oocyte autophagy. Although autophagy removes damaged proteins and subcellular organelles to maintain the cell survival, irreparable damages could induce cell death within intra-follicular microenvironment. Hypoxia-induced autophagy is operated through 5′ AMP activated protein kinase–mammalian target of rapamycin, endoplasmic reticulum stress/unfolded protein response and protein kinase C delta–c-junN terminal kinase 1 pathways in a wide variety of somatic cell types. Similar to somatic cells, we propose that hypoxia may induce granulosa cell as well as oocyte autophagy and it could be responsible at least in part for germ cell elimination from mammalian ovary. Hypoxia-mediated germ cell depletion may cause several reproductive impairments including early menopause in mammals. © 2019, Springer Nature Switzerland AG.
Development and Validation of Measure on Student-Teacher Relationship in the Indian Context
(Frontiers Media S.A., 2022) Shreshtha Yadav; Neena Kohli; Anil Kumar Yadav; Naveen; Trayambak Tiwari; Tarun Mishra
The notion that the student-teacher relationship is quintessential for the holistic development and success of students has been well established through various research. A considerable number of studies have been conducted in western countries, and various scales have been developed to measure student-teacher relationship. These scales have been extended to various cultural contexts. However, few studies have been found to focus on the suitability and applicability of these scales and theories of student-teacher relationship in the Indian context. In the western context, most of the studies on the student-teacher relationship were based on the attachment theory. In the context of Indian culture, student-teacher relationship functions beyond the boundaries of attachment theory. It is well acknowledged that Indian culture differs vastly from other cultures. Given the uniqueness of Indian culture, the present study advocated that nature of student-teacher relationship in the Indian context is significantly different from western countries. There was a need to develop a scale for measuring student-teacher relationship in the Indian context. This study intended to construct a scale on student-teacher relationship in the Indian context. Standard procedure was followed in the process of scale construction. Results of the first study illustrated a four factor (dedication, trust, respect, and obedience) model of student-teacher relationship, and a second study confirmed this model and ensured reliability and validity of the scale. Copyright © 2022 Yadav, Kohli, Yadav, Naveen, Tiwari and Mishra.
Event rate and vigilance: A psychophysiological investigation of mental workload
(Indian Academy of Applied Psychology, 2016) Anil Kumar Yadav; Shalini Dubey; I.L. Singh
Maintaining attention with concentration over prolonged periods of time during vigilance task, which may be monotonous, generally increases reaction time and errors. Such decrement in performance gets intensified during higher event rate condition. The present study was conducted on 40 male undergraduate and postgraduate students to examine the effects of event rate and task duration on behavioural, physiological and subjective measures. Two event rates were manipulated and mental workload was measured prior to and after the 40-minutes successive discrimination vigilance task. Correct responses were higher under low event rate while both event rates showed decrement in accuracy with progress in time block. Heart rate and heart rate variability pattern observed across time period in two event rate conditions were inconsistent with previous researches. Perceived mental workload increased from pre to post task session though the workload was reported as similar under high and low event rate conditions. Maintaining vigilance is a demanding task which resulted in deterioration of performance as well as mounting of perceived mental workload. Findings of present study may be implemented to work settings while designing systems and work environment, which involve vigilance functions and where production, safety and efficiency of operators are major concerns. © Journal of the Indian Academy of Applied Psychology.
Individual differences in working memory capacity and task switching performance
(Indian Academy of Applied Psychology, 2018) Shalini Dubey; Anil Kumar Yadav; Indramani L. Singh
The present study was designed to examine individual differences in working memory capacity on task switching ability. Eighty-six students whose age ranged from 18 to 30 years voluntarily participated in this study. A 2 (Working memory span group: high vs. low) x 3 (Preparation Time: 200 ms, 600 ms and 1000 ms) x 2 (Trial type: repeat and switch) mixed factorial design was employed. Participants who scored in the upper and lower quartiles on the Operation span working memory task were designated to high and low-working memory span groups respectively. Both groups performed a digit and letter classification task in alternating-runs paradigm of task switching. In this task, participant switched back and forth between digit and letter tasks in which they were required to classify either digits as odd/even or letter as vowel/consonant. Three preparation intervals were also provided between trials to prepare for forthcoming task. Results revealed that high-working memory participants were faster and more accurate in classification of digits and letters on both switch and repeat trials. High-working memory span participants endowed smaller switch cost though they showed lesser improvement with increase in preparation time. Findings of the study provide evidences for executive attention view of working memory capacity. © Journal of the Indian Academy of Applied Psychology.
Role of Workplace Spirituality, Empathic Concern and Organizational Politics in Employee Wellbeing: A Study on Police Personnel
(Frontiers Media S.A., 2022) Shreshtha Yadav; Trayambak Tiwari; Anil Kumar Yadav; Neha Dubey; Lalit Kumar Mishra; Anju L. Singh; Payal Kapoor
Employee wellbeing as a central aspect of organizational growth has been widely regarded and accepted. Therefore, a considerable growth in the number of researches focusing on employee wellbeing has been comprehended in recent years. Employee wellbeing characterizes the individual’s own cognitive interpretation of his/her life at work. The present study made an attempt to examine how workplace spirituality, empathic concern and organizational politics influences employee wellbeing. It was hypothesized that empathic concern mediates the relationship between workplace spirituality and employee wellbeing while organizational politics act as a moderator in this relationship. A survey was conducted on 253 employees working in Uttar Pradesh Police department (Uttar Pradesh, India). The results obtained revealed that workplace spirituality, empathic concern and employee wellbeing carries a positive association among them whereas these variables were found to be negatively correlated with organizational politics. Results also depicted that empathic concern significantly mediates between workplace spirituality and employee wellbeing. Further, moderated mediation analysis confirmed employee wellbeing as a function of workplace spirituality, empathic concern and organizational politics. The present study has put forward several practical implications for business practitioners and research directions for academicians, emphasizing upon the need to investigate the comprehensive impact of employee wellbeing in organization and the society as a whole. Copyright © 2022 Yadav, Tiwari, Yadav, Dubey, Mishra, Singh and Kapoor.
Synthesis and characterization of graphene oxide-based nanofluids and study of their thermal conductivity
(Springer Science and Business Media B.V., 2022) Sachin Kumar Yadav; Diptarka Roy; Anil Kumar Yadav; Pinky Sagar; Sarvesh Kumar Avinashi
In the present research work, we investigated the effect of loading mass concentrations (0.05%, 0.15%, and 0.25 mass %) and temperature (10–50 °C) on the thermal properties of graphene oxide-ethylene glycol (GO-EG) nanofluids. A two-step approach was adopted to prepare the GO-EG nanofluids with different mass proportions without any surfactant. The thermal kinetic analysis was performed by modulated DSC and TGA. Thermal stability and particle size distribution of the nanofluids were monitored by using UV–visible spectroscopy and dynamic light scattering. The experimental findings on the thermal transport characteristics of the as-prepared nanofluid samples are influenced by loading mass concentration, increasing temperature because of the high relative area of dispersed nanoparticles at higher particle concentration, dispersion quality of nanofluids. The thermal conductivity (TC) of GO-EG nanofluid shows an enhancement of 36.72% for (sample no. 3, i.e., GO 3) and shows a semi-linear dependence profile between temperature and TC, with increasing mass concentration due to the decrease in interfacial thermal resistance between GO and EG. The observed results are in good agreement with previously reported literature and reveal the promising prospect for usage as a state-of-the-art heat transport fluid in the coolant industry. © 2022, Akadémiai Kiadó, Budapest, Hungary.