Browsing by Author "Anita Patel"

Now showing 1 - 3 of 3

Clinical epidemiology of young men with lower urinary tract symptoms: The SciCOM 3 project
(Wolters Kluwer Medknow Publications, 2025) Sanjay Sinha; Sameer Trivedi; Ankur Mittal; Girdhar Singh Bora; Rishi Nayyar; Pawan Vasudeva; Anita Patel; Harbans Bansal; Vijay Kumar Sarma Madduri; Niraj Kumar; Swarnendu Mandal; Vikash Kumar; Sujith Mathew Jose; Girish G. Nelivigi; Anil Elhence; Harprit Singh
Introduction: A study was performed to determine the most common and most bothersome symptoms and clinical associations in young men (18-40 years) presenting with lower urinary tract symptoms (LUTS). Methods: Cross-sectional study was conducted across 16 centers. Urinary symptoms, impact of bladder problems, bowel symptoms, erectile dysfunction, premature ejaculation, bladder pain, non-bladder myofascial pain, and general well-being were assessed by validated questionnaires. Results: A total of 448 men (median age 30 years) were included. Nocturia ≥1 (89.1%) and feeling of incomplete bladder evacuation (76.6%) were the most common symptoms while the most bothersome symptoms were daytime frequency and nocturia (median score 5; interquartile range 2-8, for both) on the International Consultation on Incontinence Questionnaire for Male LUTS questionnaire. Bladder symptoms were associated with severe or many severe problems (response 5 or 6, on the Patient Perception of Bladder Conditions Questionnaire) in 17.8% of the patients. Men between 18 and 20 years reported greater bother with their bladder condition. Normal erections and 'very good' control over ejaculation were reported by 49.8% and 15.6%, respectively. Constipation and loose stools were reported by 22.8% and 12.9%, while bladder pain and non-bladder myofascial pain were reported by 72.5%, and 48.2%, respectively. 17.0% of the patients reported low scores on the WHO-5 Well-Being Scale. Two distinct patient clusters were identified. A larger cluster (63.9%) that presented with voiding symptoms and urgency but fewer sexual or pain symptoms, and a smaller cluster that showed pronounced sexual symptoms, pain, daytime frequency, and nocturia. Conclusions: The most common urinary symptoms in young men are nocturia and a sense of incomplete evacuation. Daytime frequency and nocturia are the most bothersome symptoms. It is important to assess associated symptoms in young men presenting with LUTS. © 2025 Indian Journal of Urology.
Does the consistency of stools define a distinct patient cohort in young men presenting with severe lower urinary tract symptoms?
(Wolters Kluwer Medknow Publications, 2025) Sanjay Sinha; Ankur Mittal; Sameer Trivedi; Harbans Bansal; Girdhar Singh Bora; Rishi Nayyar; Pawan Vasudeva; Anita Patel; Vijay Kumar Sarma Madduri; Niraj Kumar; Swarnendu Mandal; Vikash Kumar; Sujith Mathew Jose; Girish G. Nelivigi; Anil Elhence; Harprit Singh
Introduction: Constipation has long been recognized to be associated with lower urinary tract symptoms (LUTS). However, there is little clinical data on bowel symptoms in young men who present with LUTS. This study analyses the association of stool consistency with severe LUTS in young men. Methods: This study is a secondary analysis of SciCOM 3 study examining young men presenting with LUTS. Stool consistency was recorded by the Bristol Stool Chart and classified into hard stools (Class 1, 2), normal stools (Class 3, 4), and loose stools (Class 5–7). LUTS, sexual dysfunction, bladder pain, non-bladder myofascial pain, perception of problems related to the bladder, and general well-being were captured by questionnaires along with basic clinical data. The poorest score on every question of each questionnaire was categorized as “severe”. Results: Four hundred and forty-eight young men (18–40 years; median 30 years, interquartile range 25–35 years) were studied across 16 centers. Stool consistency was hard, normal, and loose in 105 (23.4%), 284 (63.4%), and 59 (13.2%), respectively. Constipation was not associated with severe LUTS. Loose stools showed an association with six of the 13 questions on the International Consultation on Incontinence Questionnaire for male LUTS. Erectile dysfunction, bladder and nonbladder pain, and general well-being were found to be associated with loose stools but not with constipation. On multinomial logistic regression analysis, recurrent urinary tract infection and low body mass index were associated with hard stools, while low maximum flow rate, severe erectile dysfunction, and severe myofascial pain were associated with loose stools. Conclusions: Loose stools are an important association in young men presenting with severe LUTS. © 2025 Indian Journal of Urology.
Secondary hydronephrosis in young men presenting with lower urinary tract symptoms: Results of the SciCOM 3 project
(Wolters Kluwer Medknow Publications, 2025) Sanjay Sinha; Sameer Trivedi; Ankur Mittal; Anita Patel; Girdhar Singh Bora; Rishi Nayyar; Pawan Vasudeva; Harbans Bansal; Vijay Kumar Sarma Madduri; Niraj Kumar; Swarnendu Mandal; Vikash Kumar; Sujith Mathew Jose; Girish G. Nelivigi; Anil Elhence; Harprit Singh
Introduction: Secondary hydronephrosis is an uncommon but potentially serious complication of lower urinary tract dysfunction. This study examines clinical associations of young men with lower urinary tract symptoms (LUTS) presenting with hydronephrosis. Methods: Secondary analysis of multicentric study examining young men presenting with LUTS. LUTS, stool consistency, sexual dysfunction, bladder pain, nonbladder myofascial pain, perception of problems related to the bladder, and general well-being were captured by questionnaires along with basic clinical data. Hydronephrosis was presumed to be secondary to lower urinary tract dysfunction if there was ureteric dilatation, it was asymptomatic, and there was no other reason based on clinical judgment. Results: Hydronephrosis was noted in 26/442 men (5.9%). Men with hydronephrosis had lower body mass index (BMI), longer duration of symptoms, larger postvoid residual (PVR), and were more likely to be diabetic and/or have a history of urinary infection (all P < 0.05). Association was noted with need to strain, reduced strength of stream, sense of incomplete evacuation, urgency, and urgency incontinence (all P < 0.05). On multivariate logistic regression analysis, BMI (P = 0.007) and PVR (P = 0.010) were independently associated. One-unit reduction in BMI was associated with 30% increase in odds of hydronephrosis, while 100 ml increase in PVR was associated with 82% increase. Receiver operator curve analysis yielded BMI ≤23 and PVR ≥80 ml as predictive of hydronephrosis. Conclusions: Secondary hydronephrosis is seen in a small number of young men with LUTS. Such men show a distinct clinical profile that can offer clinical clues useful in the algorithm for evaluation. © 2025 Indian Journal of Urology.