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Browsing by Author "Anupriya Singh"

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    PublicationBook Chapter
    Ayurvedic strategy to achieve sustainable development goal 3: Management of cancer (Arbuda)
    (Nova Science Publishers, Inc., 2022) Anupriya Singh; Anjali Upadhyay; Jyoti Singh; Ambrish Kumar Singh; Dev Nath Singh Gautam; Narendra Kumar Singh
    Cancer is the second leading cause of morbidity and mortality as well as growing health problems worldwide. Effective drugs and therapies are available for different kinds of cancer also having side effects; hence people seek relatively safer as well as cost-effective alternative and complementary medicines for the treatment of cancer. The objective of the present chapter is to provide Ayurvedic concept-based evidence for the treatment and management of cancer to the academician and researcher who garners interest in cancer. The present study provides comprehensive information about Arbuda (cancer) and its probable remedy through Ayurveda and fulfilling the Sustainable Development Goals (SDGs) that is SDG 3. Arbuda develops due to Mithya Ahar (unhealthy diet) and Mithya Vihar (unhealthy lifestyle) leading to imbalance in Vatadi Doshas (regulatory functional factors of the body) which leads to vitiation of Dhatus (major structural components of the body). Vitiated Dhatus results in the formation of muscular swelling anywhere in the body with the appearance of large, circular, immobile, less painful, slowly growing and deep-seated swelling such a clinical entity termed as Arbuda. Symptomatically, Arbuda may have a resemblance with clinical entities such as cancer. However, the exact pathogenesis of cancer does not match these two conditions, but still, it may be possibly correlated up to a certain extent. The involvement of one or two Doshas (Vata, Pitta and Kapha), produce benign neoplasm which is harmless but the association of all three Doshas (Sannipataja/Tridoshaja) produces malignant neoplasm, which is harmful. The term Dviarbuda (metastasis) and Adhyarbuda (recurrence) are considered Asadhya (incurable) and these two terminologies may be correlated to the metastatic growth of cancer cells. Management of Arbuda includes all those plants having Laghu, Ruksha and Tikshna Guna may possess Lekhana and Kaphashamak action. © 2022 Nova Science Publishers, Inc..
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    PublicationReview
    Ethnopharmacology, Phytochemistry, and Pharmacology of Ashtanga Ghrita: an Ayurvedic Polyherbal Formulation for Neurological Disorders
    (Springer Science and Business Media Deutschland GmbH, 2022) Jyoti Singh; Anupriya Singh; Vineet Sharma; Tryambak Deo Singh; Meenakshi Singh; Ruchika Garg; Rohit Sharma; Dev Nath Singh Gautam
    Purpose of Review: Ayurveda is an ancient Indian medical system with unique approaches for the treatment of various brain disorders. Ashtanga Ghrita, a cow Ghrita-based polyherbal classical formulation, has been well defined in ancient Ayurvedic texts Ashtanga Hridya to enhance speech, intellect, and memory. The formulation contains eight potent neuroprotective herbs along with clarified cow butter and milk. The review is aimed to come up with comprehensive scientific evidence regarding the plant ingredients of Ashtanga Ghrita so that it can be used for further clinical studies as well as to treat a variety of neurological diseases. Recent Findings: The plant ingredients have been practiced since ancient times for various disorders in India as well as worldwide. The plants contain various phytochemicals including terpenes, steroids, glycosides, flavonoids, alkaloids, amino acids, fatty acids, aryl esters, and carbohydrates. The collected pharmacological evidence suggests that all the plant ingredients have neuroprotective, anxiolytic, antidepressant, antioxidant, immunomodulatory, sedative, antiproliferative, and anticonvulsant activity. Summary: Based on the collected evidence, Ashtanga Ghrita may prove to be an effective neuroprotective drug and might be useful in various neurological disorders. Further, well-designed multicentric clinical trials are required to elucidate and comprehend the therapeutic potential of the formulation. © 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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