Browsing by Author "Archana Mahapatra"

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BIOMETRICAL ANALYSIS OF SCAPULA BONE OF FISHING CAT, LEOPARD CAT AND SMALL INDIAN CIVET
(ACS Publisher, 2021) Satish K. Pathak; Archana Mahapatra; Amarpal; A.M. Pawde
[No abstract available]
Clinical Physiology of Lymphatic Disorders
(CRC Press, 2025) Manju G. Preedaa; Thulasiraman Parkunan; Mukesh Kumar Bharti; Archana Mahapatra; Manish Kumar
Lymphatic disorders encompass a range of conditions affecting the lymphatic system, which plays a crucial role in maintaining fluid balance, immune function, and fat absorption. Pathophysiologically, these disorders often involve either obstruction or dysfunction of lymphatic vessels, leading to lymphedema, characterized by the accumulation of lymphatic fluid in tissues. Primary lymphedema arises from congenital malformations of the lymphatic system, while secondary lymphedema results from damage or obstruction caused by infection, surgery, radiation, or malignancy. Chronic inflammation and fibrosis are common sequelae, exacerbating fluid accumulation and tissue swelling. The impaired lymphatic drainage in these disorders disrupts immune cell trafficking and can result in recurrent infections and delayed wound healing. Additionally, lymphatic dysfunction may contribute to the development of lymphangiectasia and chylous effusions, in which lymph leaks into body cavities. Molecular studies have highlighted the roles of various genetic mutations and signaling pathways, such as vascular endothelial growth factor-C (VEGF-C)/vascular endothelial growth factor receptor 3 (VEGFR-3), in the development and progression of lymphatic disorders. Therapeutically, management focuses on symptomatic relief through physical therapies, compression garments, and, in severe cases, surgical interventions. This chapter compiles information to elucidate the complex pathophysiology of lymphatic disorders, which is crucial for developing targeted treatments and enhancing patient outcomes. © 2025 selection and editorial matter, Tanmoy Rana.
Developmental Physiology
(CRC Press, 2025) Archana Mahapatra; Prasanta Kumar Koustasa Mishra; Satish K. Pathak; Manish Kumar
This chapter delves into the intricacies of developmental physiology, tracing the biological processes regulating an animal's life from conception to death. Development continues post-birth, encompassing aging and natural changes in tissues. Development has been classified into prenatal and postnatal stages. The prenatal phase is divided into germinal, embryonic, and fetal periods. Early prenatal development starts with fertilization, forming a zygote, which undergoes cleavage, compaction, and polarization, eventually forming a blastocyst. The endometrium's role in pregnancy establishment and the intricate cellular changes during cleavage, compaction, and polarization are crucial. Development is heavily influenced by molecular and biochemical processes, encompassing gene regulation, interactions between cells, and the formation of morphogen gradients. This involves regulatory proteins, inductive interactions, morphogens, and maternal-to-zygote transition mechanisms. This chapter highlights the multifaceted nature of developmental physiology, emphasizing the interplay of genetic, cellular, and environmental factors shaping an animal's growth and development. © 2026 selection and editorial matter, Tanmoy Rana; individual chapters, the contributors.
Evaluation of supplemented protein-L-isoaspartate-O-methyltransferase (PIMT) gene of Carica papaya and Ricinus communis in stress survival of Escherichia coli BL21(DE3) cells
(Taylor and Francis Ltd., 2024) Akanksha Gupta; Pragati Mardi; Prasanta Kumar Koustasa Mishra; Anshuman Kumar; Rajesh Kumar; Archana Mahapatra; Anupama Jena; Prakash Chandra Behera
In growing plant population, effect of stress is a perturb issue affecting its physiological, biochemical, yield loss and developmental growth. Protein-L-isoaspartate-O-methyltransferase (PIMT) is a broadly distributed protein repair enzyme which actuate under stressful environment or aging. Stress can mediate damage converting protein bound aspartate (Asp) residues to isoaspartate (iso-Asp). This spontaneous and deleterious conversion occurs at an elevated state of stress and aging. Iso-Asp formation is associated with protein inactivation and compromised cellular survival. PIMT can convert iso-Asp back to Asp, thus repairing and contributing to cellular survival. The present work describes the isolation, cloning, sequencing and expression of PIMT genes of Carica papaya (Cp pimt) and Ricinus communis (Rc pimt) Using gene specific primers, both the pimts were amplified from their respective cDNAs and subsequently cloned in prokaryotic expression vector pProEXHTa. BL21(DE3) strain of E. coli cells were used as expression host. The expression kinetics of both the PIMTs were studied with various concentrations of IPTG and at different time points. Finally, the PIMT supplemented BL21(DE3) cells were evaluated against different stresses in comparison to their counterparts with the empty vector control. © 2024 Taylor & Francis Group, LLC.
GEOMETRIC MORPHOMETRIC ANALYSIS OF SCAPULAR SHAPE AND MORPHOLOGICAL PHYLOGENY AMONG BARASINGHA, SLOTH BEAR, SMALL INDIAN CIVET, STRIPED HYENA, AND INDIAN PARIAH DOG
(ACS Publisher, 2025) Satish K. Pathak; Archana Mahapatra
Understanding scapular morphology is essential for interpreting species-specific adaptations related to locomotion, muscle attachment, and ecological strategies. This study used geometric morphometric techniques to analyse scapular shape variation and morphological phylogeny in five mammalian species, barasingha (Rucervus duvaucelii), Sloth bear (Melursus ursinus), small Indian civet (Viverricula indica), striped hyena (Hyaena hyaena), and Indian Pariah dog (Canis lupus familiaris). The study was aimed to understand how scapular morphology reflects species-specific adaptations. A total of 144 homologous landmarks were digitized from high-resolution images of lateral and medial scapular surfaces. Shape variation was analysed using principal component analysis (PCA) and Procrustes ANOVA. Morphology-based clustering was performed using hierarchical UPGMA dendrograms based on PCA. Results revealed that PC1 accounted for 80.40% of shape variance (species-wise), mainly associated with acromion process orientation and scapular spine morphology. PCA analysis (surface-wise) described the lateral and medial scapular surfaces showed a more balanced variance distribution (PC1: 33.71%, PC2: 20.81%, PC3: 18.83%). Procrustes ANOVA showed a significant effect of scapular surface on shape (F = 10.34, P < 0.0001) but not on size (P = 0.0888). The phylogenetic dendrogram separated the species into two major phenetic groups. The study offers new insights into scapular shape diversity and its ecological and evolutionary significance among studied mammals. © 2025, ACS Publisher. All rights reserved.
MORPHOLOGICAL AND MORPHOMETRICAL STUDIES OF THYMUS IN NON-DESCRIPT PUPPIES
(ACS Publisher, 2020) E. Raja Raviteja; Jigyasa Rana; Archana Mahapatra; Satish K. Pathak
[No abstract available]
Perinatal diseases
(CABI International, 2023) Sabita Behera; Archana Mahapatra; Dipanwita Bhattacharya; Dayanidhi Jena
[No abstract available]
Physiology of ear and hearing
(Bentham Science Publishers, 2025) Archana Mahapatra; Satish K. Pathak; Prasanta Kumar Koustasa Mishra; Thulasiraman Parkunan
Sense organs that is eye, ear, nose, tongue and skin provide a true sense to communicate with the outer world. Ear is the organ of hearing and balance. Ear is a complex organ consisting of three divisons, the outer, middle, and inner ear. The structures of the external ear are auricle, external auditory meatus and outer layers of the tympanic membrane. The middle ear is an air filled cavity (tympanum) consists of ear ossicles, auditory tube (Eustachian tube), middle ear muscles, inner layer of the tympanic membrane. The internal ear consists of the osseous labyrinth consisting of cochlea, vestibule and semicircular canals and membranous labyrinths and the vestibular and acoustic (spiral) ganglia associated with the eighth cranial nerve (vestibulocochlear nerve). The auditory system of ear convert sound waves into neural signals. The auricle acts as a condiut to collect the sound waves. The middle ear acts as a precochlear amplifier and impedance matching device. Transduction of sound occurs in the cochlea by spiral organs (formerly known as organs of Corti) resulting in an action potential that transmits along the auditory nerve to cochlear nucleus in the brainstem for hearing. The vestibular system plays an important role in maintaining the equilibrium and balance of the animal. It is a primary sensory organ consisting of vestibule and semicircular canals which orients with respect to the gravitational field of the earth and co-ordinates the movement of various sensory organs and thus the linear, rotatory, acceleration and deacceleration movements of the animal. © 2025 Bentham Science Publishers. All rights reserved.