Browsing by Author "Arun Kumar Pandey"

Now showing 1 - 5 of 5

Aflatoxins in Cereals and Cereal-Based Products: Occurrence, Toxicity, Impact on Human Health, and Their Detoxification and Management Strategies
(MDPI, 2022) Pradeep Kumar; Akansha Gupta; Dipendra Kumar Mahato; Shikha Pandhi; Arun Kumar Pandey; Raveena Kargwal; Sadhna Mishra; Rajat Suhag; Nitya Sharma; Vivek Saurabh; Veena Paul; Manoj Kumar; Raman Selvakumar; Shirani Gamlath; Madhu Kamle; Hesham Ali El Enshasy; Jawahir A. Mokhtar; Steve Harakeh
Cereals and cereal-based products are primary sources of nutrition across the world. However, contamination of these foods with aflatoxins (AFs), secondary metabolites produced by several fungal species, has raised serious concerns. AF generation in innate substrates is influenced by several parameters, including the substrate type, fungus species, moisture content, minerals, humidity, temperature, and physical injury to the kernels. Consumption of AF-contaminated cereals and cereal-based products can lead to both acute and chronic health issues related to physical and mental maturity, reproduction, and the nervous system. Therefore, the precise detection methods, detoxification, and management strategies of AFs in cereal and cereal-based products are crucial for food safety as well as consumer health. Hence, this review provides a brief overview of the occurrence, chemical characteristics, biosynthetic processes, health hazards, and detection techniques of AFs, along with a focus on detoxification and management strategies that could be implemented for food safety and security. © 2022 by the authors.
Detection and Management Strategies for Deoxynivalenol in Food and Feed: An Overview
(CRC Press, 2022) Raman Selvakumar; Dalasanuru Chandregowda Manjunathagowda; Arun Kumar Pandey; Dipendra Kumar Mahato; Akansha Gupta; Shikha Pandhi; Raveena Kargwal; Madhu Kamle; Pradeep Kumar
Mycotoxin contamination is a global issue, but it is aggravated in warm, humid environments that encourage fungus growth and the creation of mycotoxins. Microbial contamination in agricultural and food production has a negative economic effect on the industry. Natural foods and feeds include toxins that are a significant source of worry for human and animal health. Cereals such as wheat, maize, barley, rice, and oats, as well as their products such as breakfast cereals, infant cereals, meals, feed, and baby mix, are the most often contaminated foodstuffs. DON contamination is caused by fungicide use and FHB-resistant genotypes. Important contamination in food and feed has been observed since DON is found in toxicologically significant amounts in food and feed all over the globe. Humans and animals also face significant health risks from DON-contaminated agricultural food and feed. Consumption of DON-contaminated food and feed may jeopardize human and animal health. © 2023 Pradeep Kumar, Madhu Kamle, and Dipendra Kumar Mahato.
Nivalenol Mycotoxin Concerns in Foods: An Overview on Occurrence, Impact on Human and Animal Health and Its Detection and Management Strategies
(MDPI, 2022) Pradeep Kumar; Dipendra Kumar Mahato; Akansha Gupta; Surabhi Pandey; Veena Paul; Vivek Saurabh; Arun Kumar Pandey; Raman Selvakumar; Sreejani Barua; Mandira Kapri; Manoj Kumar; Charanjit Kaur; Abhishek Dutt Tripathi; Shirani Gamlath; Madhu Kamle; Theodoros Varzakas; Sofia Agriopoulou
Mycotoxins are secondary metabolites produced by fungi that infect a wide range of foods worldwide. Nivalenol (NIV), a type B trichothecene produced by numerous Fusarium species, has the ability to infect a variety of foods both in the field and during post-harvest handling and management. NIV is frequently found in cereal and cereal-based goods, and its strong cytotoxicity poses major concerns for both human and animal health. To address these issues, this review briefly overviews the sources, occurrence, chemistry and biosynthesis of NIV. Additionally, a brief overview of several sophisticated detection and management techniques is included, along with the implications of processing and environmental factors on the formation of NIV. This review’s main goal is to offer trustworthy and current information on NIV as a mycotoxin concern in foods, with potential mitigation measures to assure food safety and security. © 2022 by the authors.
Trichothecenes in food and feed: Occurrence, impact on human health and their detection and management strategies
(Elsevier Ltd, 2022) Dipendra Kumar Mahato; Shikha Pandhi; Madhu Kamle; Akansha Gupta; Bharti Sharma; Brajesh Kumar Panda; Shubhangi Srivastava; Manoj Kumar; Raman Selvakumar; Arun Kumar Pandey; Priyanka Suthar; Shalini Arora; Arvind Kumar; Shirani Gamlath; Ajay Bharti; Pradeep Kumar
Trichothecenes (TCNs) are the mycotoxins produced by many fungal species such as Fusarium, Myrothecium, and Stachybotrys and pose a considerable health risk. Based on their characteristic functional moieties, they are divided into four categories: Type A (T-2, HT-2, diacetoxyscirpenol (DAS), harzianum A, neosolaniol (NEO) and trichodermin), Type B (deoxynivalenol (DON), nivalenol (NIV), trichothecin and fusarenon X), Type C (crotocin) and Type D (satratoxin G & H, roridin A and verrucarin A) with types A and B being the most substantial. TCNs cause growth retardation in eukaryotes, suppress seedling growth or regeneration in plants and could be a reason for animal reproductive failure. Due to the increased frequency of occurrence and widespread distribution of TCNs in food and feed, knowledge of their sources of occurrence is essential to strategise their control and management. Hence, this review provides an overview of various types and sources of TCNs, the associated biosynthetic pathways and genes responsible for production in food and feed. Further, various processing and environmental effects on TCNs production, detection techniques and management strategies are also briefly outlined. © 2022
Zearalenone in Food and Feed: Occurrence, Biosynthesis, Detection, and Management Strategies
(CRC Press, 2022) Shikha Pandhi; Ashok Kumar Yadav; Vidhi Tyagi; S. Saloni; Akansha Gupta; Surabhi Pandey; Dipendra Kumar Mahato; Pradeep Kumar; Arun Kumar Pandey; Arvind Kumar
This chapter provides information on the many sources of zearalenone (ZEN), its presence in food and feed, and its biosynthesis mechanism, with an emphasis on the effect of processing on ZEN concentration, as well as detection and management strategies. Mycotoxins are widely found in a wide variety of plant-based agricultural commodities, including grains, nuts, fruits, vegetables, and forage. ZEN is a xenoestrogen, which are exogenous chemical compounds with a structure similar to naturally occurring estrogens. ZEN is produced via the acetate-polymalonate process, which results in a nonaketide precursor that is subsequently subjected to various cyclization and modifications. ZEN can be developed in maize when it is in the field, as well as during the time of storage, especially if stored with higher moisture content and if properly dried before storage. Fusarium graminearum and Fusarium culmorum are common molds that are responsible for zearalenone mycotoxin contamination in major cereals. © 2023 Pradeep Kumar, Madhu Kamle, and Dipendra Kumar Mahato.