Browsing by Author "Ashutosh Tandon"
Now showing 1 - 3 of 3
- Results Per Page
- Sort Options
PublicationArticle Arginase activity in carcinoma of the gallbladder: A pilot study(2009) Vijay Kumar Shukla; Ashutosh Tandon; Braja Kishor Ratha; Deborshi Sharma; Tej Bali Singh; Somprakas BasuCarcinoma of the gallbladder is the third most common cancer of the gastrointestinal tract. Recent studies have shown increased arginase activity in various malignancies. The main aim of this study was to evaluate whether arginase activity increases in carcinoma of the gallbladder. The arginase activity was evaluated in serum and gallbladder tissue in 22 patients with histologically proven carcinoma of the gallbladder and 20 patients with cholecystitis using spectrophotometry and western blot assay. The Student's t-test, analysis of variance, and Student-Newman-Keuls test were used for comparison of data and for statistical significance. The mean tissue arginase and serum arginase activity (118.64±17.45 and 15.91±1.91, respectively) in cases of carcinoma of the gallbladder were significantly higher in comparison with cholecystitis (86.37±4.45 and 12.73±0.72, respectively). Subgroup analysis showed stage III gallbladder carcinoma had the maximum tissue arginase activity (142.00±21.68 U/g of tissue) followed by stage II (124.15±19.88) and stage I (108.46±6.73). This significant rise in mean tissue arginase and serum arginase activity in patients with gallbladder cancer probably supports an association between arginase activity and the malignancy. © 2009 Lippincott Williams & Wilkins, Inc.PublicationArticle Primary rectal teratoma(2008) Deborshi Sharma; Sanjeev Kumar; Ashutosh Tandon; Amrita Ghosh Kar; Mohan Kumar; V.K. Shukla[No abstract available]PublicationArticle Unconsidered cause of bowel obstruction--gossypiboma.(2008) Deborshi Sharma; Arvind Pratap; Ashutosh Tandon; Ram Chandra Shukla; Vijay K Shukla[No abstract available]