Browsing by Author "B. Sanyal"

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Adenocystic carcinoma of the uterine cervix: A clinicopathologic study
(John Wiley and Sons Ltd, 1979) S. Gupta; I.M. Gupta; B. Sanyal
Eight cases of adenocytic carcinoma of the uterine cervix, a rare histologic variant, are presented, with a brief review of 41 cases previously reported in the literature. They represent only 0.27% of 3524 cervical carcinomas that we encountered between 1962 and 1977. In all eight cases, there was early parametrial involvement, and the majority behaved aggressively. All eight patients were multiparas, and six of them were postmenopausal. Interestingly, including this series, 15 of 49 reported cases of this entity have been from India.
Aneurysmal bone cyst of scapula
(1976) G.C. Pant; B. Sanyal; B.P. Verma; B.L. Rastogi
This patient presented with a high swelling over the scapula. The presenting symptoms and radiological appearance were suggestive of aneurysmal bone cyst or giant cell tumor and histology confirmed the diagnosis. It was decided to treat the lesion by radiotherapy following initial surgery. This relieved the symptoms and swelling regressed remarkably. There is no recurrence for a period of 21 months after the initial treatment.
Blood group specific substances in saliva of patients with cervical carcinoma
(1981) Y.N. Gupta; Saroj Gupta; B. Sanyal
Secretion of blood group specific substances in saliva of 380 patients with carcinoma of the cervix was studied, along with age-matched controls. The study shows that carcinoma of the uterine cervix is much more common in non-secretors (55.0%) than in secretors (45.0%). Statistically, this difference was found to be highly significant (P < 0.001). © 1981.
Bone scanning in the diagnosis of skeletal disorders
(1979) B. Sanyal
[No abstract available]
Carcinoma lung
(1979) K. Sahni; B. Sanyal; M.N. Khanna
Carcinoma of the lung predominates in males. Smoking of bidis is also perhaps carcinogenic. Epidermoid carcinomas is the predominant lesion. Epidermoid and undifferentiated carcinomas are related to smoking. 50 per cent of cases of adenocarcinomas were females. All cases except one presented when the disease was quite advanced. 5 Fluorouracil is only effective in adenocarcinoma. Two drugs used in combination gave better palliation compared to a single drug.
Carcinoma oesophagus. (A clinical study of 43 cases)
(1973) G.C. Pant; B. Sanyal; M.N. Khanna
Surgery and radiotherapy are the main line of attack in the treatment of esophagus carcinoma. Although there is tremendous improvement in the surgical procedures, the overall results of surgical treatment are not very encouraging. With the advent of highly sophisticated equipment and techniques of radiotherapy, a high rate of cure was expected, but results have not improved. Recently radiotherapy, surgery and chemotherapy have been combined to improve the overall results. However, it is apparent that no single technique is ideal for all situations. Experience with the different treatment modalities in cancer of the esophagus in 43 patients is described.
Carcinoma of breast associated with pregnancy and lactation
(1981) K. Sahni; B. Sanyal; M.S. Agrawal; G.C. Pant; N.N. Khanna; S. Khanna
Out Of 840 Cases Of Breast Carcinoma Seen Over A Period Of Ten Years, 18 Were Found To Be Associated With Pregnancy And Lactation. According To The Mode Of Onset And Presentation Of The Disease, These Patients Were Divided Into Four Groups. The Average Age Of These Patients Was 31.9 Years Old. Thirteen Out Of 18 Patients Presented In A Very Advanced Stage Of The Disease. In A Short Period, Involvement Of Liver Was Noticed In 8, Brain In 3, And Bones And Lung In 2 Each. The Disease Was Bilaterally Simultaneous In Two Patients. The Acceleration Of Growth Was Noticed During Second And Third Trimesters Of Pregnancy As Well As During Lactation. The Termination Of Pregnancy In Three Patients Did Not Alter The Clinical Course Of The Disease. Copyright © 1981 Wiley‐Liss, Inc., A Wiley Company
Carcinoma of frontal sinus. (A case report)
(1975) G.C. Pant; B. Sanyal; B.L. Rastogi
[No abstract available]
Carcinoma of the anal canal
(1980) B. Sanyal; G.C. Pant; K. Sahni; M.S. Agrawal; B.N. Bhatnagar; S.K. Roy; S. Gupta
104 cases of tumours of the anal canal were registered in the Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, out of a total of 11,147 cases over a period of 10 years. The frequency was 0.98% of all cases. Squamous cell carcinoma was the most common tumour. All patients presented in a fairly advanced stage of the disease, 50% of which presented with inguinal lymph adenopathy at the first presentation. Only 55 patients out of 104 completed radiotherapy. 28 patients were managed on a curative line and 16 on a palliative basis. The majority of the patients had relief of symptoms following radiotherapy, but the overall survival at 3 and 5 years in this series was 41% and 33%, respectively. This presentation highlights the clinical spectrum of the cases, and the role of radiotherapy in the management of these tumours has been stressed.
Carcinoma of the middle ear
(1979) B. Sanyal; G.C. Pant; M.S. Agarwal
[No abstract available]
Chemotherapy For Advanced Oral Cancer
(Georg Thieme Verlag, 2024) N.N. Khanna; A. Khanna; G.C. Pant; B. Sanyal; S. Khanna
A combination of three drugs, cyclophosphamide, methotrexate and 5-Fluorouracil was tried in 50 consecutive cases of advanced oral cancer. The overall response rate was 66%, and the incidence of toxicity 18%. The response was better in primary cases as compared to those who had received prior radiotherapy. However the response was shortlived. © 2024 Georg Thieme Verlag. All rights reserved.
Combined treatment modalities for intracranial tumours
(1978) B. Sanyal; G.C. Pant; K. Subrahmaniyam; K. Sahni; M.S. Agarwal; S. Mohanty; C.J. Rao; P.K. Shukla
[No abstract available]
Desquamation of malignant cells in carcinoma of the uterine cervix: Its role in prognosis
(1982) Saroj Gupta; Y.N. Gupta; Abha Rani; B. Sanyal; S. Khanna
Percentage of malignant cell exfoliation in relation to that of benign epithelial cells was studied in pretreatment vaginal smears of 251 patients of squamous cell carcinoma of the cervix. The rate of exfoliation did not increase with increasing clinical severity. Also, the various cell types of squamous cell carcinoma and clinical radiation response were independent of number of malignant cells shed in the vagina. However, the group of patients having a fewer number of malignant cells in their vaginal smears had a statistically significantly better five‐year survival. Copyright © 1982 Wiley‐Liss, Inc., A Wiley Company
Erythrocyte survival studies in lymphomas: A prognostic appraisal
(1977) B. Sanyal; K. Subrahmanyam; G.C. Pant
Erythrocyte survival studies using Radioactive Chromium-51 were made in 20 lymphoma patients and 10 control subjects at the Centre of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi. Monitoring of the counts over hepatic, splenic and cardiac areas was done to detect hypersplenism. The normal T1/2 values ranged from 25-45 days with a mean of 35 days in our series. A majority of the patients with lymphomas showed reduced T1/2 values. The following observations could be made: (1) Patients with advanced disease (Stages III and IV) showed significantly reduced T1/2 values. (ii) None of the patients with the histologic varieties of L.P. and N.S. showed T1/2 values less than 20 days even in Stage III. (iii) Patients with M.C. even when in Stage II and with normal T1/2 values succumbed to the disease within 2 years. (iv) A majority of patients with L.D. were seen in Stage III and had T1/2 of 15 days and died within 2 years. (v) Low R.B.C. T1/2 values do not seem to have a bad prognostic significance in non-Hodgkin's lymphomas (period of observation 2 years 6 months). (vi) A significant correlation could be shown between R.B.C. T1/2 values and Hb%. Similarly, patients with normal or near normal T1/2 values had a higher A.E.C. compared to lower values observed in patients with low T1/2 values. This may be a reflection upon the diminishing immunologic status of the patients with advanced disease and R.B.C. T1/2. However, no significant correlation could be observed between T1/2 and A.L.C. In the final analysis, it appears that for Hodgkin's disease there is a good correlation between the stage of the disease, histologic variety, Hb%, T1/2 and survival status of the patients.
Ewing's sarcoma: A combined approach in the management
(1981) G.C. Pant; B. Sanyal; K. Sahni; S.M. Tuli; T.P. Srivastava
Twenty-seven histologically confirmed cases of localised Ewing's sarcoma were treated by two different regimes. Radiotherapy alone was used in 13 cases and a combination of chemotherapy and radiotherapy in 14. Single agent chemotherapy (cyclophosphamide) was given sequentially in nine patients and cyclophosphamide and actinomycin-D in five. There is a significant difference in the response to these different regimes. Only 69.2% of patients treated by radiotherapy alone were disease-free, for a median period of 10.4 months and metastases were noticed in 53.8% of cases. The disease-free survival in patients treated by combination therapy (radiotherapy and chemotherapy) was 18.4 months and metastases were seen in only 42.9%. However, no metastases were seen in patients who received cyclophosphamide and actinomycin-D, during a period of 14 months and only one patient showed residual disease. It is concluded that the addition of cyclophosphamide alone is not adequate in the management of Ewing's sarcoma. Actinomycin-D in addition to cyclophosphamide has improved the disease-free survival period significantly. The optimum dose of radiotherapy and its combination with other chemotherapeutic agents needs further trials to find the best and most suitable schedule. © 1981 Royal College of Radiologists.
Ewing's tumour of the vertebrae
(1988) V. Mohan; S.K. Gupta; S.M. Tuli; B. Sanyal
[No abstract available]
Exit dose measurement for correct assessment of doses under radiotherapy in cancer cervix patients
(1987) A.K. Asthana; M.S. Agrawal; B. Sanyal
[No abstract available]
Extramedullary plasmacytoma: Simulating a soft tissue sarcoma of the chest wall
(1980) B. Sanyal; G.C. Pant; K. Sahni; S. Khanna; R.M. Gupta; N.N. Khanna
Extramedullary plasmacytoma occurs infrequently as compared to osseous myoloma. A single case of extramedullary plasmacytoma was seen during the last 10 years whose initial presentation was that of a soft tissue sarcoma of the chest wall. Clinical data along with relevent investigation and treatment results are discussed with a review of the literature. Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company
Hemangiopericytoma: report of three cases regarding role of radiation therapy
(1976) H. Lal; B. Sanyal; G.C. Pant; B.L. Rastogi; N.N. Khanna; K.N. Udupa
The experience in treating three patients with hemangiopericytoma is reviewed. One patient was given irradiation alone, and the others were both treated with surgery and irradiation. Personal experience reinforces reports of the usefulness of irradiation in treating this neoplasm and its metastases.
Histiocytes in vaginal smears: As prognostic parameter in carcinoma of the uterine cervix
(1981) Saroj Gupta; Abha Rani; Y.N. Gupta; B. Sanyal; S. Khanna
Pretreatment vaginal smears of 251 patients with carcinoma of the cervix were counted for the percentage of histiocyte count in relation to benign squamous epithelial cells. No correlation was found between the percentage of histiocyte count and the age of the patient, clinical stage, cell type of squamous cell carcinoma, and clinical radiation response. Also a high histiocyte count is found to be unrelated to 5‐year survival, recurrence, metastasis, or death of these patients. The present study indicates that the histiocyte number appears to have no relationship with immediate or remote prognosis in patients with carcinoma of cervix uteri. Copyright © 1981 Wiley‐Liss, Inc., A Wiley Company