Browsing by Author "B.N. Upadhyay"

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Assessment of the adrenergic beta-blocking activity of inula racemosa
(1988) Y.B. Tripathi; Pratibha Tripathi; B.N. Upadhyay
Inula racemosa root powder was investigated in patients with proven ischaemic heart disease. The powder prevented ST-segment depression and T-wave inversion as observed in the post-exercise electrocardiogram. The petroleum ether extract of roots lowered plasma insulin and glucose levels within 75 min of oral administration to albino rats and it significantly counteracted adrenaline-induced hyperglycaemia in rats. The extract further showed negative inotropic and negative chronotropic effects on frog heart. All these findings indicate that one of the constituents of Inula racemosa may have adrenergic beta-blocking activity. © 1988.
Concept of aging in Ayurveda
(2009) Bal Govind Tiwari; B.N. Upadhyay
Ayurveda is one of the oldest recognized systems of medicine, originated from Vedas. Now at this time, the whole world is showing renewed interest in the aging process and aged people. In first 50 yrs of 21St century old age dependency ratio is expected to double in more developed region and triple in less developed region, thus the age people are going to be a big problem for the society. It is the best time to explore the possibilities of a drug from Ayurveda, which can be given to the aged person and improve their life span.
Immunomodulating and antiproteinuric effect of hippophae rhamnoides (Badriphal) in idiopathic nephrotic syndrome
(2013) Rana Gopal Singh; Parampal Singh; Praveen Kumar Singh; Usha; Aruna Agrawal; B.N. Upadhyay; Ashutosh Soni
Objective: The treatment of idiopathic nephrotic syndrome is still not well settled and at times is very frustrating. Number of protocols have been reported with variable results outcome in various conditions. The main pillar of treatment of idiopathic nephrotic syndrome is use of immunomodulating and suppressive drugs in various combinations. The herbal preparations have also been reported to have immunomodulating property. The study has been planned to record Immunomodulating and antiproteinuric effect of Hippophae rhamnoides. Material and Methods: In the present study had 2 groups having 28 patients of idiopathic nephrotic syndrome in each group have been included. The patients were subjected to haematological, biochemical, immunological investigation at 0, 1, 2 and 3 months interval with dietic advise. Group A have been put on standard treatment, whereas group B on Badriphal in the well worked up doses. The hydroalcoholic extract of 350 mg twice daily of Badriphal was given to group B as add on treatment. Patients were followed up with definite protocol at monthly interval for 3 months. Results: At the end of 3 month patients showed improvement in the symptoms of oedema, anorexia, oliguria in the herbal group. The urinary estimation of protein showed significant decrease in Group B with elevation of S. albumin levels. The inflammatory cytokines has show ed significant decrease at the end of 3 month. Conclusion: Thus the pilot study showed beneficial effect of the herbal preparation Hippophae rhamnoides as add on treatment. A large perspective study is recommended to establish these findings. © JAPI.
The electrochemical behavior of 9Cr-1Mo steel in concentrated acid solution mixtures
(1998) V.B. Singh; B.N. Upadhyay
The electrochemical polariztion behaviour of 9Cr-1Mo steel has been investigated in binary and ternary mixtures of concentrated phosphoric acid, acetic acid, sulphuric acid, and formic acid at 20±1°C. The steel showed active-passive and transpassive behaviour in all solutions. The alloy surface exhibited a tendency to undergo electropolishing in acetic acid-based phosphoric acic electrolytes. In the transpassive region, a current plateau was always observed but electropolishing occurred only in a few selected mixtures (10-20 volume percent acetic acid + balance phosphoric acid). The experimental results reveal that electropolishing is under mass transport control and the existence of a current plateau is not a sufficient condition. A low content of water is beneficial for electropolishing.