Browsing by Author "Cristina Prat"

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International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia
(W.B. Saunders Ltd, 2019) Stefano Aliberti; Grayden S. Cook; Bettina L. Babu; Luis F. Reyes; Alejandro H. Rodriguez; Francisco Sanz; Nilam J. Soni; Antonio Anzueto; Paola Faverio; Ricardo Franco Sadud; Irfan Muhammad; Cristina Prat; Ester Vendrell; Joao Neves; Evangelos Kaimakamis; Andrew Feneley; Rajesh Swarnakar; Fabio Franzetti; Manuela Carugati; Manuela Morosi; Elisa Monge; Marcos I. Restrepo; Patricia Karina Aruj; Silvia Attorri; Enrique Barimboim; Juan Pablo Caeiro; María I. Garzón; Victor Hugo Cambursano; Adrian Ceccato; Julio Chertcoff; Florencia Lascar; Fernando Di Tulio; Ariel Cordon Díaz; Lautaro de Vedia; Maria Cristina Ganaha; Sandra Lambert; Gustavo Lopardo; Carlos M. Luna; Alessio Gerardo Malberti; Nora Morcillo; Silvina Tartara; Claudia Pensotti; Betiana Pereyra; Pablo Gustavo Scapellato; Juan Pablo Stagnaro; Sonali Shah; Felix Lötsch; Florian Thalhammer; Kurt Anseeuw; Camille A. Francois; Eva Van Braeckel; Jean Louis Vincent; Marcel Zannou Djimon; Jules Bashi; Roger Dodo; Simone Aranha Nouér; Peter Chipev; Milena Encheva; Darina Miteva; Diana Petkova; Adamou Dodo Balkissou; Eric Walter Pefura Yone; Bertrand Hugo Mbatchou Ngahane; Ning Shen; Jin-Fu Xu; Carlos Andres Bustamante Rico; Ricardo Buitrago; Fernando Jose Pereira Paternina; Jean-Marie Kayembe Ntumba; Vesna Vladic Carevic; Marko Jakopovic; Mateja Jankovic; Zinka Matkovic; Ivan Mitrecic; Marie-Laure Bouchy Jacobsson; Anette Bro Christensen; Uffe Christian Heitmann Bødtger; Christian Niels Meyer; Andreas Vestergaard Jensen; Gertrud Baunbæk-Knudsen; Pelle Trier Petersen; Stine Andersen; Ibrahim El-Said Abd El-Wahhab; Nesreen Elsayed Morsy; Hanaa Shafiek; Eman Sobh; Kedir Abdella Abdulsemed; Fabrice Bertrand; Christian Brun-Buisson; Etienne de Montmollin; Muriel Fartoukh; Jonathan Messika; Pierre Tattevin; Abdo Khoury; Bernard Ebruke; Michael Dreher; Martin Kolditz; Matthias Meisinger; Mathias W. Pletz; Stefan Hagel; Jan Rupp; Tom Schaberg; Marc Spielmanns; Petra Creutz; Norton Suttorp; Beatrice Siaw-Lartey; Katerina Dimakou; Dimosthenis Papapetrou; Evdoxia Tsigou; Dimitrios Ampazis; Mohit Bhatia; Raja Dhar; George D’souza; Rajiv Garg; Parvaiz A. Koul; P.A. Mahesh; B.S. Jayaraj; Kiran Vishnu Narayan; Hirennappa B. Udnur; Shashi Bhaskara Krishnamurthy; Surya Kant; Sneha Limaye; Sundeep Salvi; Keihan Golshani; Vera M. Keatings; Ignacio Martin-Loeches; Yasmin Maor; Jacob Strahilevitz; Salvatore Battaglia; Maria Carrabba; Piero Ceriana; Marco Confalonieri; Antonella D’Arminio Monforte; Bruno Del Prato; Marino De Rosa; Riccardo Fantini; Giuseppe Fiorentino; Maria Antonia Gammino; Francesco Menzella; Giuseppe Milani; Stefano Nava; Gerardo Palmiero; Roberta Petrino; Barbra Gabrielli; Paolo Rossi; Claudio Sorino; Gundi Steinhilber; Alessandro Zanforlin; Mauro Carone; Vincenzo Patella; Simone Scarlata; Andrea Comel; Kiyoyasu Kurahashi; Zeina Aoun Bacha; Daniel Barajas Ugalde; Omar Ceballos Zuñiga; José F. Villegas; Milic Medenica; E.M.W. van de Garde; Deebya Raj Mihsra; Poojan Shrestha; Elliott Ridgeon; Babatunde Ishola Awokola; Ogonna N.O. Nwankwo; Adefuye Bolanle Olufunlola; Segaolu Olumide; Kingsley N. Ukwaja; Muhammad Irfan; Lukasz Minarowski; Skoczynski Szymon; Felipe Froes; Pedro Leuschner; Mariana Meireles; Cláudia Ferrão; Sofia B. Ravara; Victoria Brocovschii; Chesov Ion; Doina Rusu; Cristina Toma; Daniela Chirita; Carmen Mihaela Dorobat; Alexei Birkun; Anna Kaluzhenina; Abdullah Almotairi; Zakeya Abdulbaqi Ali Bukhary; Jameela Edathodu; Amal Fathy; Abdullah Mushira Abdulaziz Enani; Nazik Eltayeb Mohamed; Jawed Ulhadi Memon; Abdelhaleem Bella; Nada Bogdanovic; Branislava Milenkovic; Dragica Pesut; Luis Borderìas; Noel Manuel Bordon Garcia; Hugo Cabello Alarcón; Catia Cilloniz; Antoni Torres; Vicens Diaz-Brito; Xavier Casas; Alicia Encabo González; Maria Luisa Fernández-Almira; Miguel Gallego; Inmaculada Gaspar-García; Juan González Del Castillo; Patricia Javaloyes Victoria; Elena Laserna Martínez; Rosa Malo de Molina; Pedro J. Marcos; Rosario Menéndez; Ana Pando-Sandoval; Cristina Prat Aymerich; Alicia Lacoma de la Torre; Ignasi García-Olivé; Jordi Rello; Silvia Moyano; Oriol Sibila; Ana Rodrigo-Troyano; Jordi Solé-Violán; Ane Uranga; Job FM van Boven; Ester Vendrell Torra; Jordi Almirall Pujol; Charles Feldman; Ho Kee Yum; Arnauld Attannon Fiogbe; Ferdaous Yangui; Semra Bilaceroglu; Levent Dalar; Ufuk Yilmaz; Artemii Bogomolov; Naheed Elahi; Devesh J. Dhasmana; Rhiannon Ions; Julie Skeemer; Gerrit Woltmann; Carole Hancock; Adam T. Hill; Banu Rudran; Silvia Ruiz-Buitrago; Marion Campbell; Paul Whitaker; Alexander Youzguin; Anika Singanayagam; Karen S. Allen; Veronica Brito; Jessica Dietz; Claire E. Dysart; Susan M. Kellie; Ricardo A. Franco-Sadud; Garnet Meier; Mina Gaga; Thomas L. Holland; Stephen P. Bergin; Fayez Kheir; Mark Landmeier; Manuel Lois; Girish B. Nair; Hemali Patel; Katherine Reyes; William Rodriguez-Cintron; Shigeki Saito; Julio Noda; Cecilia I. Hinojosa; Stephanie M. Levine; Luis F. Angel; K. Scott Whitlow; John Hipskind; Kunal Sukhija; Vicken Totten; Richard G. Wunderink; Ray D. Shah; Kondwelani John Mateyo; Lorena Noriega; Ezequiel Alvarado; Mohamed Aman; Lucía Labra
Objective: Streptococcus pneumoniae is the most frequent bacterial pathogen isolated in subjects with Community-acquired pneumonia (CAP) worldwide. Limited data are available regarding the current global burden and risk factors associated with drug-resistant Streptococcus pneumoniae (DRSP) in CAP subjects. We assessed the multinational prevalence and risk factors for DRSP-CAP in a multinational point-prevalence study. Design: The prevalence of DRSP-CAP was assessed by identification of DRSP in blood or respiratory samples among adults hospitalized with CAP in 54 countries. Prevalence and risk factors were compared among subjects that had microbiological testing and antibiotic susceptibility data. Multivariate logistic regressions were used to identify risk factors independently associated with DRSP-CAP. Results: 3,193 subjects were included in the study. The global prevalence of DRSP-CAP was 1.3% and continental prevalence rates were 7.0% in Africa, 1.2% in Asia, and 1.0% in South America, Europe, and North America, respectively. Macrolide resistance was most frequently identified in subjects with DRSP-CAP (0.6%) followed by penicillin resistance (0.5%). Subjects in Africa were more likely to have DRSP-CAP (OR: 7.6; 95%CI: 3.34-15.35, p<0.001) when compared to centres representing other continents. Conclusions: This multinational point-prevalence study found a low global prevalence of DRSP-CAP that may impact guideline development and antimicrobial policies. © 2019
Microbiological testing of adults hospitalised with community-acquired pneumonia: An international study
(European Respiratory Society, 2018) Manuela Carugati; Stefano Aliberti; Luis Felipe Reyes; Ricardo Franco Sadud; Muhammad Irfan; Cristina Prat; Nilam J. Soni; Paola Faverio; Andrea Gori; Francesco Blasi; Marcos I. Restrepo; Patricia Karina Aruj; Silvia Attorri; Enrique Barimboim; Juan Pablo Caeiro; María I. Garzón; Victor Hugo Cambursano; Adrian Ceccato; Julio Chertcoff; Ariel Cordon Díaz; Lautaro De Vedia; Maria Cristina Ganaha; Sandra Lambert; Gustavo Lopardo; Carlos M. Luna; Alessio Gerardo Malberti; Nora Morcillo; Silvina Tartara; Claudia Pensotti; Betiana Pereyra; Pablo Gustavo Scapellato; Juan Pablo Stagnaro; Sonali Shah; Felix Lötsch; Florian Thalhammer; Kurt Anseeuw; Camille A. Francois; Eva Van Braeckel; Jean Louis Vincent; Marcel Zannou Djimon; Jules Bashi; Roger Dodo; Simone Aranha Nouér; Peter Chipev; Milena Encheva; Darina Miteva; Diana Petkova; Adamou Dodo Balkissou; Eric Walter Pefura Yone; Bertrand Hugo Mbatchou Ngahane; Ning Shen; Jin-Fu Xu; Carlos Andres Bustamante Rico; Ricardo Buitrago; Fernando Jose Pereira Paternina; Jean-Marie Kayembe Ntumba; Vesna Vladic Carevic; Marko Jakopovic; Mateja Jankovic; Zinka Matkovic; Ivan Mitrecic; Marie Laure Bouchy Jacobsson; Anette Bro Christensen; Uffe Christian Heitmann Bødtger; Christian Niels Meyer; Andreas Vestergaard Jensen; Gertrud Baunbæk-Knudsen; Pelle Trier Petersen; Stine Andersen; Ibrahim El-Said Abd El-Wahhab; Nesreen Elsayed Morsy; Hanaa Shafiek; Eman Sobh; Kedir Abdella Abdulsemed; Fabrice Bertrand; Christian Brun-Buisson; Etienne De Montmollin; Muriel Fartoukh; Jonathan Messika; Pierre Tattevin; Abdo Khoury; Bernard Ebruke; Michael Dreher; Martin Kolditz; Matthias Meisinger; Mathias W. Pletz; Stefan Hagel; Jan Rupp; Tom Schaberg; Marc Spielmanns; Petra Creutz; Norton Suttorp; Beatrice Siaw-Lartey; Katerina Dimakou; Dimosthenis Papapetrou; Evdoxia Tsigou; Dimitrios Ampazis; Evangelos Kaimakamis; Mina Gaga; Mohit Bhatia; Raja Dhar; George D’Souza; Rajiv Garg; Parvaiz A. Koul; P.A. Mahesh; B.S. Jayaraj; Kiran Vishnu Narayan; Hirennappa B. Udnur; Shashi Bhaskara Krishnamurthy; Surya Kant; Rajesh Swarnakar; Sneha Limaye; Sundeep Salvi; Keihan Golshani; Vera M. Keatings; Ignacio Martin-Loeches; Yasmin Maor; Jacob Strahilevitz; Salvatore Battaglia; Maria Carrabba; Piero Ceriana; Marco Confalonieri; Antonella D’Arminio Monforte; Bruno Del Prato; Marino De Rosa; Riccardo Fantini; Giuseppe Fiorentino; Maria Antonia Gammino; Francesco Menzella; Giuseppe Milani; Stefano Nava; Gerardo Palmiero; Roberta Petrino; Barbra Gabrielli; Paolo Rossi; Claudio Sorino; Gundi Steinhilber; Alessandro Zanforlin; Fabio Franzetti; Manuela Morosi; Elisa Monge; Mauro Carone; Vincenzo Patella; Simone Scarlata; Andrea Comel; Kiyoyasu Kurahashi; Zeina Aoun Bacha; Daniel Barajas Ugalde; Omar Ceballos Zuñiga; José F. Villegas; Milic Medenica; E.M.W. Van De Garde; Deebya Raj Mihsra; Internal Medicine; Poojan Shrestha; Elliott Ridgeon; Babatunde Ishola Awokola; Ogonna N. O. Nwankwo; Adefuye Bolanle Olufunlola; Segaolu Olumide; Kingsley N. Ukwaja; Lukasz Minarowski; Skoczyński Szymon; Felipe Froes; Pedro Leuschner; Mariana Meireles; Cláudia Ferrão; João Neves; Serviço De Medicina; Sofia B. Ravara; Victoria Brocovschii; Chesov Ion; Doina Rusu; Cristina Tom; Daniela Chirita; Carmen Mihaela Dorobat; Alexei Birkun; Anna Kaluzhenina; Abdullah Almotairi; Zakeya Abdulbaqi Ali Bukhary; Jameela Edathodu; Amal Fathy; Abdullah Mushira Abdulaziz Enani; Nazik Eltayeb Mohamed; Jawed Ulhadi Memon; Abdelhaleem Bella; Nada Bogdanović; Branislava Milenkovic; Dragica Pesut; Charles Feldman; Ho Kee Yum; Luis Borderìas; Noel Manuel Bordon Garcia; Hugo Cabello Alarcón; Catia Cilloniz; Antoni Torres; Vicens Diaz-Brito; Xavier Casas; Alicia Encabo González; Maria Luisa Fernández-Almira; Miguel Gallego; Inmaculada Gaspar-García; Juan González Del Castillo; Patricia Javaloyes Victoria; Elena Laserna Martínez; Rosa Malo De Molina; Pedro J. Marcos; Rosario Menéndez; Ana Pando-Sandoval; Cristina Prat Aymerich; Jordi Rello; Silvia Moyano; Francisco Sanz; Oriol Sibila; Ana Rodrigo-Troyano; Jordi Solé-Violán; Ane Uranga; Job F. M. Van Boven; Ester Vendrell Torra; Jordi Almirall Pujol; Arnauld Attannon Fiogbe; Ferdaous Yangui; Semra Bilaceroglu; Levent Dalar; Ufuk Yilmaz; Artemii Bogomolov; Naheed Elahi; Andrew Feneley; Rhiannon Ions; Julie Skeemer; Gerrit Woltmann; Carole Hancock; Adam T. Hill; Banu Rudran; Silvia Ruiz-Buitrago; Marion Campbell; Paul Whitaker; Alexander Youzguin; Anika Singanayagam; Karen S. Allen; Veronica Brito; Jessica Dietz; Claire E. Dysart; Susan M. Kellie; Ricardo A. Franco-Sadud; Garnet Meier; Thomas L. Holland; Stephen P. Bergin; Fayez Kheir; Mark Landmeier; Manuel Lois; Girish B. Nair; Hemali Patel; Katherine Reyes; William Rodriguez-Cintron; Shigeki Saito; Julio Noda; Cecilia I. Hinojosa; Stephanie M. Levine; Luis F. Angel; Antonio Anzueto; K. Scott Whitlow; John Hipskind; Kunal Sukhija; Vicken Totten; Richard G. Wunderink; Ray D. Shah; Kondwelani John Mateyo; Devesh J. Dhasmana; Lorena Noriega; Ezequiel Alvarado; Mohamed Aman; Lucía Labra
This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations. © ERS 2018.