Browsing by Author "D.S. Singh"

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Acute diarrhoea in elderly
(1999) I.S. Gambhir; J.P. Jaiswal; A.K. Singh; D.S. Singh
[No abstract available]
Acute non-calculus cholecystitis in virus B hepatitis.
(1996) D.S. Singh; S.R. Saxena; A.K. Singh; I.S. Gambhir
[No abstract available]
Artificial culture, host infection and pycnidial development of Ascochyta sorghina Sacc
(Kluwer Academic Publishers, 1977) D.S. Singh; M.S. Pavgi
Mode of penetration and subsequent development of Ascochyta sorghina Saccardo in the leaf tissues of sorghum (Sorghum vulgare Pers.) were studied under field conditions. Penetration by A. sorghina was observed both directly through the epidermis and indirectly through the stomatal openings in the leaves. The pathogen produced intercellular mycelium, which later became intracellular after death of cells around the infection site through action of toxic metabolites produced by the pathogen. The pycnidia developed through the growth of a subcuticular hyphal crust. © 1977 Dr. W. Junk b.v.
Blood coagulation in patients with acute infectious hepatitis in india
(1976) A. Dube; J.P. Gupta; D.S. Singh; V.N. Sinha; Sulekha Bhattacharya; Ramakanta Dube
Coagulation studies were performed in 61 patients of acute infective hepatitis. 18 with clinical signs of liver failure had bleeding and all succumbed. The 47 patients without liver failure showed no haemorrhagic diathesis and all of them had uneventful recovery. Though coagulopathy was present in most of the patients, the severity and frequency of coagulation defects were more in those with signs of hepatic failure. Hypofibrinogenemia, elevated serum fibrinogen degradation products and accelerated euglobulin lysis were conspicuous in patients with hepatic failure. It appears that while diminished synthesis of coagulation factors is the main basis for coagulopathy in patients without hepatic failure, additional factors like local or disseminated intravascular coagulation and increased fibrinolysis also contribute significantly to the coagulopathy in cases of liver failure. © 1976 by S. Karger AG, Basel.
Cardiac changes in acute viral hepatitis in Varanasi (India): Case reports
(1989) D.S. Singh; P.R. Gupta; S.S. Gupta; P.K. Bhatia; P.N. Somani; I.S. Gambhir; A.K. Khare
Three cases of acute viral hepatitis are reported with various cardiac changes such as transient left ventricular hypertrophy, myocarditis and progressive cardiomegaly (cardiomyopathy). Extra-hepatic manifestations of acute viral hepatitis are rare but have been well documented. The aims of the present study are to highlight the cardiac involvement in acute viral hepatitis and to report the clinical implications of cardiac changes in acute viral hepatitis.
Conidial release in pyricularia penniseti
(1973) D.S. Singh; M.S. Pavgi
Conidiophores and conidia of Pyricularia penniseti Prasada and Goyal undergo violent hygroscopic movements when transferred from humid to dry atmosphere. The conidia are detached and dispersed forcibly from the conidiophores as a result of these movements. Although the conidia are not projected to long distances, the forcible detachment facilitates further removal by air currents to hasten secondary infection of the younger host leaves in succession. © 1973 S. Karger AG, Basel.
Constipation: A common gut dysmotility problem in the elderly
(1999) D.S. Singh; A.K. Singh; A. Mehrotra; I.S. Gambhir
[No abstract available]
Discovery of Elephas cf. namadicus from the late Pleistocene strata of Marginal Ganga Plain
(Geological Society of India, 2016) Rupa Ghosh; R.K. Sehgal; Pradeep Srivastava; U.K. Shukla; A.C. Nanda; D.S. Singh
We describe an elephant skull recovered from a cliff section of Dhasan river of Marginal Ganga Plain. The dental morphology and cranial features of the skull have been compared with the known species of Elephas from the Indian subcontinent. Although it shows very near resemblance to Elephas namadicus, but being an isolated specimen its specific identity cannot be proclaimed with certainty. As such, the specimen is provisionally referred as E. cf. namadicus. The Optically Stimulated Luminescence ages place this find at ~56 ka BP. This is the first chronologically well constrained report of E. cf. namadicus from the Ganga Plain. © 2016, Geological Society of India.
Electrocardiographic changes in relation with CT scan parameters in spontaneous intracerebral haemorrhage
(1997) I.S. Gambhir; S.S. Gupta; D.S. Singh; A. Srivastva
Sixty-three patients of spontaneous intracerebral hemorrhage proved by computerised axial tomography (CT) scan were studied for electrocardiographic (ECG) changes and their correlation with CT scan parameters. ECG changes were observed in 81% (51 patients) with 28% mortality as compared to 9% mortality in patients without ECG changes. In 87% of survivors ECG changes regressed in 1st week of hospitalisation. ECG changes in all three parameters i.e. automaticity, conduction and repolarisation correlated well with mortality (60%), ventricular communication (VC), mass effect (ME) and volume of hematoma.
Evaluation of CSF-Adenosine Deaminase Activity in Tubercular Meningitis
(1999) I.S. Gambhir; M. Mehta; D.S. Singh; H.D. Khanna
Sixty patients of inflammatory brain disease were diagnosed and classified according to clinico-investigational criteria by Ahuja et al into tuberculous meningitis group (36 patients) and non-tuberculous meningitis group (24 patients). Tuberculous meningitis (TBM) patients were classified as probable (9 patients) and possible (27 patients) TBM. Non-TBM group comprised of pyogenic meningitis (8.3%), viral encephalitis (23.3%), cerebral malaria (5%) and enteric encephalopathy (3.3%). Cerebrospinal fluid-adenosine deaminase (CSF-ADA) activities were measured in both TBM and non-TBM groups. Mean CSF-ADA levels in TBM patients was 9.61 ± 4.10 IU/L and was significantly elevated as compared to viral encephalitis and enteric encephalopathy cases; but difference was insignificant in comparison to pyogenic meningitis (7.92 ± 0.95 IU/L) and cerebral malaria. Using 8 IU/L as cut off value for diagnosis of TBM a sensitivity of 44% and specificity of 75% was observed.
Evaluation of some fungicides against Pyricularia penniseti causing brown leaf spot of Bajra
(1973) D.S. Singh; M.S. Pavgi
[No abstract available]
Gonococcemia
(1974) H.S. Girgla; G. Singh; D.S. Singh
[No abstract available]
Health problems in rural elderly at Varanasi, Uttar Pradesh
(1996) A.K. Singh; Manju Singh; D.S. Singh
Present study comprised of 1070 elderly patients coming to P.H.C. Bhopauli, Varanasi during January 1991-December 1992. Males were 578 and females were 492. Male predominance was present in younger elderly whereas female predominance was seen among those over 75 years of age. Socio-economic status-wise 265 cases belonged to upper, 394 middle and 411 to lower income group. Arthritis (615) was the commonest disease in elderly followed by hypertension (510), visual problems (400), ischaemic heart disease (IHD) (350), hearing impairement (300), diabetes mellitus (DM) (280), protozoal and worm infestations (240), chronic bronchitis, asthma, emphysema (238),tuberculosis (220), peptic ulcer syndrome (210), varicose vein (200), haemorrhoids (180), urinary problems (154).Two hundred and forty seven cases had 2 diseases followed by 3 diseases (239), 4 diseases (165), 5 diseases (127) and more than 5 diseases (81). Multiple diseases were more frequent among those above 75 years of age. Atypical presentations and complications of different diseases were more frequent among older elderly.
Hepatic encephalopathy
(1998) I.S. Gambhir; D.S. Singh; A. Mehrotra
[No abstract available]
Herpes Simplex Virus -1 Encephalitis in Eastern Uttar Pradesh
(1999) I.S. Gambhir; N.N. Singh; D.S. Singh; A.K. Gulati
• Objective : To study the proportion of HSV-1 encephalitis in acute viral encephalitis. • Methods : One hundred and five patients presenting with clinical diagnosis of acute viral encephalitis and with exclusion of other possible causes of acute inflammatory brain disease prevalent in the area by relevent laboratory investigations were included in the study. Ninety single CSF samples were tested for HSV-1 IgM antibodies by ELISA test supplied by Dia Medix Corporation, USA. CT Scan and EEG studies were carried out in 25 patients. • Results : Clinical and neuro investigational profile of patients suggested a low incidence of HSV-1 encephalitis in the study group. IgM antibodies were present in CSF sample of one patient only. • Conclusion : HSV-1 encephalitis constitutes a very low proportion (1.1%) of acute viral encephalitis cases seen in Eastern Uttar Pradesh (India).
Humoral immunity in pediatric Kalaazar patients in India
(1997) L. Usha; A. Dikshit; D.S. Singh; S. Sunder; Z. Ali; R.M. Gupta
The study included 20 patients of Kalaazar in children and 20 healthy children of same age group. Mostly patients were males (75%) and in age group of 3 to 10 years. Humoral immunity was assessed by total serum protein, immunoglobulin estimation and circulating immune complexes. Significant hyperproteinemia was found in patient group as compared to control (p<.001). Ninety percent children had increased IgG above 1600 mg/dl (Mean 2392 ± 715.11 mg/dl). Similarly serum IgM and IgA were also significantly raised in comparison to controls (IgA 178 ± 74 59 mg/dl IgM 194.5 ± 89.8 mg/dl). Except one patient almost all had significant increase in circulating immune complexes (79 78 ± 22.55%). None of the patients had glomerulonephritis, vasculitis or arthritis.
Immunity and common infections in elderly
(1999) Usha; T. Sharma; D.S. Singh; I.S. Gambhir; R.G. Singh
[No abstract available]
In vitro assay of some fungicides and antibiotics against two foliicolous fungi on Jowar
(1973) D.S. Singh; M.S. Pavgi
[No abstract available]
Influence of extrusion conditions on the colour of millet-legume extrudates using digital imagery
(Teagasc, 2014) Subir K. Chakraborty; D.S. Singh; B.K. Kumbhar
Colour acts as one of the triggers for acceptance of snack foods. Digital imaging in conjunction with Adobe Photoshop can help identification of variations in the colour of extruded products. Response surface methodology-based central composite rotatable designed experiments were conducted to understand the colour components and overall acceptability (OAA) of extruded snacks made from millet–legume blends, 12–28% legume, at different moisture content (MC) of 12–24% wet basis (w.b.), extruded at varying die head temperatures (DHT) from 160–200 °C, barrel temperatures from 100–140 °C and screw speeds of 100–140 rpm. A simple digital camera was used for capturing the images of the extrudates. An L*a*b* colour model (where L* is the black/ white element, a* is green/red and b* is blue/yellow) was used for colour characterization and OAA was determined by a hedonic scale. It was inferred from the analysis of the resulting statistically valid second order models for the responses that all the colour components were significantly affected by the amount of legume in the extruder feed and by the DHT. It was also observed that DHT, synergistically with other processing parameters, had a significant effect on all the responses. The OAA was highest for the extrudates with higher L* values. Optimum processing conditions were derived while the responses adhered to constraints. The responses of the extrudates prepared under optimum conditions exhibited no significant variation from model predicted values. © 2014, Teagasc. All rights reserved.
Isolation and characterization of NADP+-linked isocitrate dehydrogenase of germinating pea seeds (Pisum sativum)
(2001) P.K. Srivastava; D.S. Singh
NADP+-linked isocitrate dehydrogenase (E.C.I.1.1.42) has been purified to homogeneity from germinating pea seeds. The enzyme is a tetrameric protein (mol wt, about 146,000) made up of apparently identical monomers (subunit mol wt, about 36,000). Thermal inactivation of purified enzyme at 45° and 50°C shows simple first order kinetics. The enzyme shows optimum activity at pH range 7.5-8. Effect of substrate [S] on enzyme activity at different pH (6.5-8) suggests that the proton behaves formally as an "uncompetitive inhibitor". A basic group of the enzyme (site) is protonated in this pH range in the presence of substrate only, with a pKa equal to 6.78. On successive dialysis against EDTA and phosphate buffer, pH 7.8 at 0°C, yields an enzymatically inactive protein showing kinetics of thermal inactivation identical to the untreated (native) enzyme. Maximum enzyme activity is observed in presence of Mn2+ and Mg2+ ions (3.75 mM). Addition of Zn2+, Cd2+, Co2+ and Ca2+ ions brings about partial recovery. Other metal ions Fe2+, Cu2+ and Ni2+ are ineffective.