Browsing by Author "Deeksha Singh"

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A cross sectional study on analysis of human milk as per prakriti psychosomatic constitution
(Enviro Research Publishers, 2020) Deeksha Singh; B.M. Singh; Sangeeta Gehlot; Vandana Verma
Background: Ayurveda scholars have given comprehensive descriptions about characteristics of pure and vitiated human milk, measures of its purification, effect of diet, lifestyle on quality of human milk and its effect on growth and development of infant. Recent researches have also shown that the variation in human milk composition is associated with the maternal diet, environment, and potentially with genetic factors. Studies have reported that individual mothers within species often demonstrate variation in milk composition and/or yield affecting infant growth and development. Prakriti refers to genetic account of an individual, so there may be variation in human milk composition because of metabolic peculiarity and dietary differences. Aim and Objectives: To analyze the composition of pure and vitiated Human milk as per Prakriti. Materials and Method: Total 200 healthy lactating Indian mothers, aged between 20 to 35 years were registered after getting informed written consent from OPD of Department of Kaumar bhritya, I.M.S, BHU, Varanasi, India during year 2015-2017. Analysis of milk for fat, SNF, density, protein, lactose, freezing point, conductivity and pH was done through Eco milk Analyzer. The vitiation of milk was assessed by water test mentioned in Ayurveda text viz. Charak Samhita, Sushruta Samhita, Ashtanghridyam, Kashyap Samhita etc. Assessment of Prakriti (Psychosomatic constitution) of mothers was done by validated Performa. Results: The mean values of different constituents viz. Fat(%), SNF(%),Density(g/cm3), Protein (%) and Freezing Point(°C) were more in vitiated milk as compared to pure human milk. The variation in composition of milk was also found as per Psychosomatic constitution, the mean values in milk varied significantly as per Prakriti (p=0.0287). On applying Post Hoc Test, the significant pairs were for Vata v/s Pitta (<0.05) and Vata v/s Kapha (<0.05) Prakriti. Conclusion: Present study suggests that the composition of human milk varies as per Prakriti and in vitiated state too. Thus by correction of diet and lifestyle as per Prakriti, the quality of breast milk may be improved and better growth of infants may be obtained by using medicines for purification of milk. © 2020 The Author(s). Published by Enviro Research Publishers.
Diagnosis of Genital Tuberculosis in Infertile Women by Using the Composite Reference Standard
(Hindawi Limited, 2022) Riden Saxena; Kriti Shrinet; Sachchida Nand Rai; Kamal Singh; Shivi Jain; Shuchi Jain; Deeksha Singh; Shampa Anupurba; Madhu Jain
Female genital tuberculosis (FGTB) can be asymptomatic or even masquerade as other gynecological conditions. Conventional methods of FGTB diagnosis include various imaging, bacteriological, molecular, and pathological techniques that are only positive in a small percentage of patients, leaving many cases with undiagnosed condition. In the absence of a perfect diagnostic method, composite reference standards (CRSs) have been advocated in this diagnostic study. This study assesses the agreement between traditional diagnostic modalities using CRS and prevalent TB groups among different fallopian tube infertility manifestations. A total of 86 women with primary and secondary infertility were included in the study and subjected to bacteriological, pathological, and radiological examination for the diagnosis of FGTB. Results were evaluated statistically for concordance of the diagnostic tests to the CRS by sensitivity and specificity, while PPV and NPV were calculated for the performance of diagnostic tests of FGTB. We observed that 11.2% of women were found to be true positives by means of CRS. The positive findings by CRS were as follows: ultrasonography (13.9%), laparoscopy (14%), hysteroscopy (12%), GeneXpert (4.8%), culture (4.8%), polymerase chain reaction (4.8%), and histopathology (6.4%). GeneXpert and culture were found to have a perfect agreement with CRS. Hysterosalpingography, laparoscopy, and hysteroscopy have a fair agreement with CRS. Out of 43 women with tubal factor infertility, 6 women were found in the definitive TB group with mixed conditions of tubal manifestations. This study evaluates and demonstrates the reliability of the collective assessment of various diagnostic methods with CRS findings that help in identifying different TB groups of genital tuberculosis patients from all infertile patients by applying the criteria of CRS. © 2022 Riden Saxena et al.
Variations of human milk compositions as per prakriti (Psychosomatic constitution): A pilot study
(Informatics Publishing Limited, 2019) Deeksha Singh; Sangeeta Gehlot; B.M. Singh; D.C. Rai
Introduction: Mother’s milk is considered to be the supreme food for neonates, infants and toddler. It is also regarded as the finest gift form a mother to her baby. The individual characteristic of a person enumerating external and internal body features is known as Prakriti. It is the sense of personality or constitution or temperament of an individual. The aim of the present study was to assess “variations of human milk composition as per Prakriti”. Materials and Methods: Total 64 lactating mothers of 20-35 years age group, not suffering from any acute or chronic illness and who were on similar diet regardless of their mode of delivery were registered and included in the study while lactating mothers not falling in this age group or who were taking any specific drug for the illness or suffering from any disease including- moderate (9.97-7 g/dl) to severe (6.94-4 g/dl) anemia were excluded from the study. Result: On applying One Way ANOVA, the mean values of fat percentage in milk varied significantly as per Prakriti (p = 0.0287). On applying Post Hoc Test the significant pairs were for Vata vs. Pitta (<0.05) and Vata vs Kapha (<0.05) Prakriti. In all other parameters of milk, no significant variation was found. Conclusion: We can conclude that the composition of mother’s milk varies as per Prakriti. © 2019, Informatics Publishing Limited, All rights reserved.