Browsing by Author "Deepak Kumar Gautam"

Now showing 1 - 5 of 5

Aromatherapy in combating human pathogens and diseases: Impact and prospects
(Har Krishan Bhalla and Sons, 2025) Monisha Soni; Manish Kumar Jha; Umakant Banjare; Arati Yadav; Prem Shankar Upadhyay; Deepak Kumar Gautam; N. K. Dubey; A. K. Dwivedy
The article deals with a comprehensive understanding of the origin, application, status quo, and therapeutic significance of aromatherapy and provides a better and more systematic understanding of the potential therapeutic effects of essential oils (EOs) as aromatherapeutants against human pathogens. EOs used in aromatherapy have significant therapeutic effects over physical, psychological, and behavioural problems in addition to having antifungal, antibacterial, antiviral, and antiparasitic properties. Looking into a large number of cases of antimicrobial resistance caused due to overuse and misuse of antibiotics, aromatherapy holds a promising future and vapours of different EOs can be used to treat human diseases. However, the lack of standardized formulations is the major obstacle in broad-scale application of aromatherapy. Hence, future research should focus on optimizing the best concentrations and delivery systems for EOs to ensure its efficacy and safety before using it as an aromatherapeutant. Through nanotechnology, more efficacious and cost effective nanoformulations of traditional aromatherapeutants may be prepared. The integration of aromatherapy with modern medicine will contribute greatly towards reshaping the existing health care system by increasing the collaboration between modern allopathy and certified aromatherapists. This may result in increased public interest and accessibility of aromatherapy around the globe. © 2025 Har Krishan Bhalla & Sons.
Case report: Histoplasmosis accompanying disseminated tuberculosis in an immunocompetent adolescent boy
(American Society of Tropical Medicine and Hygiene, 2020) Ashis Kumar Choudhury; Ankit Kumar Mishra; Deepak Kumar Gautam; Ragini Tilak; Vijai Tilak; Indrajeet Singh Gambhir; Sankha Shubhra Chakrabarti
The incidence of tuberculosis in India is quite high. In such a situation, empirical antitubercular therapy (ATT) is often resorted to, when some of the investigation findings are clearly diagnostic of tuberculosis. This may mean missing out on coinfections. Whereas this is particularly true for immunosuppressed patients, rarely even immunocompetent patients may present with such diagnostic dilemmas.Wepresent the case of an adolescent boy who had been previously asymptomatic and who presented with fever with lymphadenopathy, splenomegaly, and pancytopenia. Initially, ATT was administered based on the detection of acid-fast bacteria in lymph node, caseating granulomas with Langhans giant cells, and a positive cartridge-based nucleic acid amplification test specific for Mycobacterium tuberculosis. However, when the patient failed to respond fully to the treatment, additional investigation in the form of bone marrow fungal culture led to the diagnosis of histoplasmosis. © 2020 by The American Society of Tropical Medicine and Hygiene.
Impacts assessment of municipal solid squander dumping in riparian corridor using multivariate statistical techniques
(Springer Singapore, 2017) Abaidya Nath Singh; Deepak Kumar Gautam; Pankaj Kumar; Devendra Mohan
Crumbling soil quality and reduction in vegetation plenitude are grave outcomes of open squanders dumping which have brought about growing public concern. The center of the present study is to assess the contribution of open squander dumping in riparian soil contamination and its impact on plant assorted qualities in riparian corridor of river Varuna. Surface soil sample (n = 6 + 2) was gathered from both the open squander dumping and control site. The assorted qualities of vegetation were learned at both sites. Significant changes were seen in the soil attributes of the dumping sites. Soils at the dumping indicated high pH, TDS and EC regime in contrast with control site. The assorted qualities of vegetation were also learned at both sites. A comparable pattern was seen in plant assorted qualities. Control site indicated differentiated assortment of plants, i.e., 12 plant species while this number decreased at the dumping sites. The principal component analysis created three significant components explaining 95.764 of the variance in the data attributable to open dumping effect. Hierarchical cluster analysis grouped six-dumping sites into three clusters having similar characteristics and source of contamination, i.e., moderate and highly polluted dumping sites. © Springer Nature Singapore Pte Ltd. 2017. All rights reserved.
Sheehan syndrome with Gitelman syndrome, Tackling Additive Morbidity
(NLM (Medline), 2019) Sukdev Manna; Sankha Shubhra Chakrabarti; Deepak Kumar Gautam; Indrajeet Singh Gambhir
Sheehan syndrome (SS) is postpartum hypopituitarism resulting from pituitary gland necrosis caused by severe hypotension due to massive intra or post-partum hemorrhage. Defective NaCl transport in the distal convoluted tubule, due to mutations affecting the thiazide sensitive Na-Cl-cotransporter results in the autosomal recessive salt-losing renal tubulopathy, Gitelman syndrome (GS). These two have been rarely described together. We report the case of a middle-aged woman with both these conditions, resulting in management issues. Physicians encountering unexplained hypokalemia refractory to standard management must consider the possibility of renal tubular disorders.
Sheehan syndrome with Gitelman syndrome, tackling additive morbidity
(Iranian Society of Nephrology, 2019) Sukdev Manna; Sankha Shubhra Chakrabarti; Deepak Kumar Gautam; Indrajeet Singh Gambhir
Sheehan syndrome (SS) is postpartum hypopituitarism resulting from pituitary gland necrosis caused by severe hypotension due to massive intra or post-partum hemorrhage. Defective NaCl transport in the distal convoluted tubule, due to mutations affecting the thiazide sensitive Na-Cl-cotransporter results in the autosomal recessive salt-losing renal tubulopathy, Gitelman syndrome (GS). These two have been rarely described together. We report the case of a middle-aged woman with both these conditions, resulting in management issues. Physicians encountering unexplained hypokalemia refractory to standard management must consider the possibility of renal tubular disorders. © 2019, Iranian Society of Nephrology. All rights reserved.