Browsing by Author "G. Singh"

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A clinico-mycological study of tinea pedis in North Eastern India
(1985) C. Ramanan; G. Singh; P. Kaur
A total of 2306 patients were examined for the clinical evidence of tinea pedis. Only 52 of these were found to suffer from this condition. Trichophyton rubrum was the commonest (47.6%) isolate and it produced predominantly non-inflammatory scaly lesions. T. mentagrophytes was the next commonest (21.4%) agent: it was responsible for most of the macerated lesions.
A new solid-state pH sensor and its application in the construction of all solid-state urea biosensor
(Wiley-VCH Verlag, 2000) P.C. Pandey; S. Upadhyay; G. Singh; R. Prakash; R.C. Srivastava; P.K. Seth
A new solid-state pH sensor is developed using neutral poly(3-cyclohexyl thiophene) assembled over a Pt disk electrode. The new sensor is developed following two different approaches; 1) the neutral poly(3-cyclohexyl-thiophene) dissolved in chloroform and subsequent coating on to a Pt disk electrode; 2) the neutral polymer is incorporated into plasticized poly(vinyl chloride) matrix membrane. In both cases the polymer modified electrode is sensitive to pH and a reversible super Nernstian behavior is observed. The typical response of the pH sensor and its reversibility are reported. The polymer coated electrode is subsequently used to construct an all solid-state urea sensor. The construction of this new urea sensor involves the following two major steps; a) 20 μL of urease solution (40 mg/mL) is allowed to assemble overnight at 4 °C over neutral poly (3-cyclohexyl thiophene) modified electrode; b) an organically modified sol-gel layer is allowed to form over the urease adsorbed polymer modified electrode. The new solid-state urea sensor provides excellent reproducibility of the measurements and is stable for 3 months when stored at 4 °C under dry condition. The typical response of the solid-state urea sensor and the calibration plot of urea analysis are reported.
A novel ferrocene encapsulated palladium-linked ormosil-based electrocatalytic dopamine biosensor
(2001) P.C. Pandey; S. Upadhyay; Ida Tiwari; G. Singh; V.S. Tripathi
A novel finding on the development of electrocatalytic biosensor for dopamine is reported. The new electrocatalytic dopamine biosensor is developed using ferrocene encapsulated palladium (Pd)-linked organically-modified sol-gel glass (ormosil). The alkoxy precursors used for the preparation of new ormosil-based electrocatalytic biosensor are palladium-linked glycidoxypropyltrimethoxysilane and trimethoxysilane. The optimum concentrations of these precursors are added in aqueous solution of ferrocene monocarboxylic acid and HCl followed by gelation for 30 h at 25°C to form ormosil. The ferrocene encapsulated ormosil is characterized based on cyclic voltammetric measurements. The CV results shows peak separation of 57-59 mV and a linear relation between peak current and square root of scan rate suggesting well behaved reversible electrochemistry of ormosil encapsulated ferrocene. The CV results and the detection of ferrocene in working medium shows that ferrocene is not leached out of ormosil matrix. The tyrosinase is immobilized within polyvinyl alcohol over the ferrocene encapsulated new ormosil and finally mounted using nucleopore membrane. The electrocatalytic response of immobilized tyrosinase over new ormosil is observed and the results are reported. The performance, stability, and reproducibility of new ormosil-based dopamine biosensor are reported. © 2001 Elsevier Science B.V.
A review of literature along with a cadaveric study of the prevalence of the Giacomini vein (the thigh extension of the small saphenous vein) in the Indian population
(2008) Prakash; Jyoti Kumari; N. Nishanth Reddy; P. Kalyani Rao; T. Preethi Ramya; G. Singh
Short saphenous has most variable anatomy in the inferior extremity which become more relevant especially in varicose vein surgery. Present study on cadavers was undertaken to report the prevalence of the thigh extension of the short saphenous vein (Giacomini vein) in the Indian population and to discuss it with the prior studies reported in the literature on other populations. Dissection was performed on both the sides of 50 embalmed cadavers to study the prevalence of the Giacomini vein. Mode of termination of the proximal extension of the short saphenous vein in the thigh was studied for different criteria. Ninety-two percent of the lower extremities showed prevalence of the Giacomini vein. In 71% specimens the short saphenous vein terminated into the popliteal vein. Most common mode of extension in the thigh was anastomosis with the great saphenous vein. Prevalence of Giacomini vein in Indian population was highest (92%) compared to previous studies by various authors in other populations. Aforementioned anatomical facts including the mode of termination of the thigh extension of the short saphenous vein can be important for surgeons planning intervention in this area. The complex anatomy of this vein and different reports in the literature regarding its clinical significance suggest further studies in this direction.
A shift from significance test to hypothesis test through power analysis in medical research
(2006) G. Singh
Medical research literature until recently, exhibited substantial dominance of the Fisher's significance test approach of statistical inference concentrating more on probability of type I error over Neyman-Pearson's hypothesis test considering both probability of type I and II error. Fisher's approach dichotomises results into significant or not significant results with a P value. The Neyman-Pearson's approach talks of acceptance or rejection of null hypothesis. Based on the same theory these two approaches deal with same objective and conclude in their own way. The advancement in computing techniques and availability of statistical software have resulted in increasing application of power calculations in medical research and thereby reporting the result of significance tests in the light of power of the test also. Significance test approach, when it incorporates power analysis contains the essence of hypothesis test approach. It may be safely argued that rising application of power analysis in medical research may have initiated a shift from Fisher's significance test to Neyman-Pearson's hypothesis test procedure.
A study of neuroticism in skin patients
(1975) O.N. Srivastava; V.K. Bhat; G. Singh
A questionnaire study of neuroticism was done on 200 skin patients attending a general hospital skin out patients department. They were found to have significantly higher neuroticism scores than normal population. The neuroticism scale employed was the P.G.I. Health Questionnaire. On the basis of this questionnaire no differences in neuroticism scores between traditional 'organic' and 'functional' groups of skin disorders were observed. The scabies patients did not differ from normal in the neuroticism scores, whereas neurodermatitis, vitiligo and leprosy patients were farther from normals in that order. The probable fallacies of such a study and its limitations in establishing any causal relationship between psyche and soma are discussed. It is suggested that for studying such relationship between psyche and soma, intensive study of a limited number of patients is just as important as a large scale (and therefore necessarily superficial) study. The latter though permitting statistical manipulations may lead to oversimplification.
A variation of the phrenic nerve: Case report and review
(2007) Prakash; L.V. Prabhu; S. Madhyastha; G. Singh
During routine dissection in the department of anatomy, the following anatomical variations of the phrenic nerve were observed on the right side of the neck of a 30-year-old male cadaver. The phrenic nerve, in its early course close to its origin, gave a communicating branch to the C5 root of the brachial plexus. At the level of the root of neck just before entering the thorax, the phrenic nerve was located anterior to the subclavian vein. This unique case of phrenic nerve variation gains tremendous importance in the context of subclavian vein cannulation, implanted venous access portals, and supraclavicular nerve block for regional anaesthesia.
Acne cornea or oil acne simulating pityriasis rubra pilaris
(1976) R. Singh; B.S.N. Reddy; G. Singh
[No abstract available]
An improved model for bioassay of topical corticosteroids
(1988) P.K. Singh; G. Singh
[No abstract available]
An interdisciplinary framework for using archaeology, history and collective action to enhance India's agricultural resilience and sustainability
(IOP Publishing Ltd, 2020) A.S. Green; S. Dixit; K.K. Garg; N.R. Sandya; G. Singh; K. Vatta; A.M. Whitbread; M.K. Jones; R.N. Singh; C.A. Petrie
South Asia has a deep history of agriculture that includes a range of past farming systems in different climatic zones. Many of these farming systems were resilient to changes in climate and sustainable over long periods of time. India's present agricultural systems are facing serious challenges, as they have become increasingly reliant on the unsustainable extraction of groundwater for irrigation. This paper outlines an interdisciplinary framework for drawing on patterns from the past to guide interventions in the present. It compares past and present strategies for water management and use in semi-arid and temperate Punjab with equatorial Telangana. Structural differences in water use in these two regions suggest that a range of interventions should be adopted to expand the overall availability of surface water for agricultural systems in India, in combination with empowering local communities to create their own water management rules. Active interventions focus on the efficient use of water supplies, and increasing surface water availability through renovation of collective ponds and reservoirs. We argue that this conceptual framework has significant potential for guiding agronomic and economic interventions in the future. © 2020 The Author(s). Published by IOP Publishing Ltd.
An unusual presentation of chronic discoid lupus erythematosus
(1976) B.S.N. Reddy; G. Singh
[No abstract available]
Analysis of an azimuthally periodic vane-loaded cylindrical waveguide for a gyro-travelling-wave tube
(1999) G. Singh; S.M.S. Ravi Chandra; P.V. Bhaskar; P.K. Jain; B.N. Basu
A cylindrical waveguide, with wedge-shaped metal vanes projecting radially inward from the wall of the guide, excited in the transverse electric mode, was analyzed. The analysis was carried out considering the angular harmonics generated in the Fourier amplitudes of field constants. The shape of the dispersion characteristics and the value of the cutoff frequency as well as the interaction impedance characteristics of the waveguide depend on the vane parameters, their numbers as well as their radial and angular dimensions.
Antimicroial sensitivity pattern of Neisseria gonorrhoeae
(1983) K.G. Singh; G. Singh; H.S. Girgla
[No abstract available]
Antiseborrhoeic action of anthralin
(1975) G. Singh
[No abstract available]
Anxiety and hyperhidrosis
(1977) S.N. Shrivastava; G. Singh
Palmoplantar hyperhidrosis is a very common problem. It is frequently seen in young adults. In almost all cases it is not possible to determine the cause. It is usually attributed to anxiety or emotional factors. The authors studied anxiety in 32 patients using Hindi version of Middlesex-Hospital-Questionnaire and compared with normal controls. They did not find any difference between the 2 groups. Anxiety perhaps is not a major etiological factor in palmar and plantar hyperhidrosis.
Assessment of irritant quality of detergents
(1991) S. Singh; S.S. Pandey; G. Singh
[No abstract available]
Association of MDR-TB isolates with clinical characteristics of patients from Northern region of India
(Wolters Kluwer Medknow Publications, 2014) A. Gupta; M.R. Nagaraja; P. Kumari; G. Singh; R. Raman; S.K. Singh; S. Anupurb
Purpose: We sought to determine the characteristics and relative frequency of transmission of MDR-TB in North India and their association with the clinical and epidemiological characteristics of TB-patients. Materials and Methods: To achieve the objectives PCR-SSCP, MAS-PCR and direct DNA sequencing were used against 101 Mycobacterium tuberculosis isolates. Results: Multidrug-resistant-TB isolates were found to be significantly higher (P = 0.000) in previously treated patients in comparison to newly diagnosed patients. Further, significant differences (P = 0.003) were observed between different age groups (Mean ± SD, 28.6 ± 11.77) of the TB patients and multidrug resistance. Most frequent mutations were observed at codons 531 and 315 of rpoB and katG genes, respectively, in MDR-TB isolates. Conclusion: Routine surveillance of resistance to anti-TB drugs will improve timely recognition of MDR-TB cases and help prevent further transmission in Northern India.
Associations of environments in South Asia based on spot blotch disease of wheat caused by Cochliobolus sativus
(2007) A.K. Joshi; G. Ortiz-Ferrara; J. Crossa; G. Singh; G. Alvarado; M.R. Bhatta; E. Duveiller; R.C. Sharma; D.B. Pandit; A.B. Siddique; S.Y. Das; R.N. Sharma; R. Chand
Spot blotch is an important disease of wheat (Triticum aestivum L.) in South Asia. Division of test sites for this disease into homogenous subregions is expected to contribute to more efficient evaluation and better differentiation of cultivars. Data from a collaborative regional program of South Asia conducted by CIMMYT were analyzed to group testing sites into relatively homogenous subregions for spot blotch area under the disease progress curve (AUDPC). Five-year data of eight locations from Eastern Gangetic Plains Nursery (EGPSN) and five locations of the Eastern Gangetic Plains Yield Trial (EGPYT) conducted in three countries (India, Nepal, and Bangladesh) of South Asia were used. A hierarchical cluster analysis was used to group locations on the basis of genotype x location interaction effects for spot blotch AUDPC. Cluster analysis divided South Asia into two broad regions and four subregions. This classification was not entirely consistent with the geographic distribution of locations, but clusters mostly followed general geographic-climatic locations. The locations Varanasi (India) and Bhairahawa (Nepal) were identified as the most suitable sites for evaluation of spot blotch, followed by Rampur (Nepal). The major determinant for the clustering was mean temperature. The results suggest that the major wheat region of South Asia can be divided into subregions, which may reduce the cost of resistance evaluation and aid in developing wheat with resistance to this disease. © Crop Science Society of America.
Asymptomatic gonorrhoea in males
(1979) P. Kaur; P.K. Jha; G. Singh
[No abstract available]
B-lactamase producing Neisseria gonorrhoeae
(1984) K.G. Singh; G. Singh; P. Kaur
[No abstract available]