Browsing by Author "G.C. Pant"

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A study on electron filters in reducing surface dose in cobalt-60 teletherapy
(1977) M.S. Agrawal; G.C. Pant; P.C. Sood
[No abstract available]
Aneurysmal bone cyst of scapula
(1976) G.C. Pant; B. Sanyal; B.P. Verma; B.L. Rastogi
This patient presented with a high swelling over the scapula. The presenting symptoms and radiological appearance were suggestive of aneurysmal bone cyst or giant cell tumor and histology confirmed the diagnosis. It was decided to treat the lesion by radiotherapy following initial surgery. This relieved the symptoms and swelling regressed remarkably. There is no recurrence for a period of 21 months after the initial treatment.
Carcinoma oesophagus. (A clinical study of 43 cases)
(1973) G.C. Pant; B. Sanyal; M.N. Khanna
Surgery and radiotherapy are the main line of attack in the treatment of esophagus carcinoma. Although there is tremendous improvement in the surgical procedures, the overall results of surgical treatment are not very encouraging. With the advent of highly sophisticated equipment and techniques of radiotherapy, a high rate of cure was expected, but results have not improved. Recently radiotherapy, surgery and chemotherapy have been combined to improve the overall results. However, it is apparent that no single technique is ideal for all situations. Experience with the different treatment modalities in cancer of the esophagus in 43 patients is described.
Carcinoma of breast associated with pregnancy and lactation
(1981) K. Sahni; B. Sanyal; M.S. Agrawal; G.C. Pant; N.N. Khanna; S. Khanna
Out Of 840 Cases Of Breast Carcinoma Seen Over A Period Of Ten Years, 18 Were Found To Be Associated With Pregnancy And Lactation. According To The Mode Of Onset And Presentation Of The Disease, These Patients Were Divided Into Four Groups. The Average Age Of These Patients Was 31.9 Years Old. Thirteen Out Of 18 Patients Presented In A Very Advanced Stage Of The Disease. In A Short Period, Involvement Of Liver Was Noticed In 8, Brain In 3, And Bones And Lung In 2 Each. The Disease Was Bilaterally Simultaneous In Two Patients. The Acceleration Of Growth Was Noticed During Second And Third Trimesters Of Pregnancy As Well As During Lactation. The Termination Of Pregnancy In Three Patients Did Not Alter The Clinical Course Of The Disease. Copyright © 1981 Wiley‐Liss, Inc., A Wiley Company
Carcinoma of frontal sinus. (A case report)
(1975) G.C. Pant; B. Sanyal; B.L. Rastogi
[No abstract available]
Carcinoma of the anal canal
(1980) B. Sanyal; G.C. Pant; K. Sahni; M.S. Agrawal; B.N. Bhatnagar; S.K. Roy; S. Gupta
104 cases of tumours of the anal canal were registered in the Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, out of a total of 11,147 cases over a period of 10 years. The frequency was 0.98% of all cases. Squamous cell carcinoma was the most common tumour. All patients presented in a fairly advanced stage of the disease, 50% of which presented with inguinal lymph adenopathy at the first presentation. Only 55 patients out of 104 completed radiotherapy. 28 patients were managed on a curative line and 16 on a palliative basis. The majority of the patients had relief of symptoms following radiotherapy, but the overall survival at 3 and 5 years in this series was 41% and 33%, respectively. This presentation highlights the clinical spectrum of the cases, and the role of radiotherapy in the management of these tumours has been stressed.
Carcinoma of the middle ear
(1979) B. Sanyal; G.C. Pant; M.S. Agarwal
[No abstract available]
Carcinomatous neuromuscular syndromes: A clinical and quantitative electrophysiological study
(1978) Thomas Paul; B.C. Katiyar; Surendra Misra; G.C. Pant
[No abstract available]
Chemotherapy For Advanced Oral Cancer
(Georg Thieme Verlag, 2024) N.N. Khanna; A. Khanna; G.C. Pant; B. Sanyal; S. Khanna
A combination of three drugs, cyclophosphamide, methotrexate and 5-Fluorouracil was tried in 50 consecutive cases of advanced oral cancer. The overall response rate was 66%, and the incidence of toxicity 18%. The response was better in primary cases as compared to those who had received prior radiotherapy. However the response was shortlived. © 2024 Georg Thieme Verlag. All rights reserved.
Clinicopathological profile and therapeutic appraisals in lymphoma in eastern Uttar Pradesh
(1997) V.P. Singh; S. Sundar; S. Gupta; B.L. Rastogi; M. Kumar; G.C. Pant; A. Jain; N. Gera
Ninety-four patients of lymphoma (55 of Non-Hodgkin's and 39 of Hodgkin's) were evaluated for clinical profile, histological subtypes and therapeutic outcome. Out of 94, 'B' symptoms were present in 66, lymphadenopathy in 82 and anaemia in 50 patients. Forty-three patients presented in stage IV. Mixed cellularity (53.8%) was the most common histologic subtype in Hodgkin's disease and diffuse mixed (30.5%) in non-Hodgkin's lymphoma. Initial complete remission rates as seen with chemotherapeutic regimes were 74.1% with COPP in Hodgkin's disease and 58.3% with CVP and 75% with CHOP in non-Hodgkin's lymphoma.
Combined treatment modalities for intracranial tumours
(1978) B. Sanyal; G.C. Pant; K. Subrahmaniyam; K. Sahni; M.S. Agarwal; S. Mohanty; C.J. Rao; P.K. Shukla
[No abstract available]
Double cancer (A report on two cases)
(1990) A.K. Asthana; S. Pradhan; R.K. Jain; G.C. Pant; M. Kumar
[No abstract available]
Double cancer. (Epidermoid carcinoma with chronic myeloid leukaemia)
(1973) G.C. Pant; M.L. Mehrotra
The association of chronic myeloid leukemia with another primary neoplasm is rare when compared with chronic lymphatic leukemia. Two cases, one having epidermoid carcinoma of the anus and another having epidermoid carcinoma of the cervix concurrently with chronic myeloid leukemia, are reported. Neither of them had a past history of radiation. Both cases were treated by radiation and Myleran. A short review of literature is discussed.
Effect of oblique incidence on surface dose in cobalt-60 teletherapy and use of silver filter
(1977) M.S. Agrawal; P.C. Sood; G.C. Pant
[No abstract available]
Effect of S.S.D. on surface dose
(1979) M.S. Agrawal; P.C. Sood; G.C. Pant
[No abstract available]
Efficacy of a silver filter in reducing the surface dose in 60Co teletherapy
(1979) M.S. Agrawal; P.C. Sood; G.C. Pant
One of the advantages of 60Co radiations in the treatment of malignant diseases is its skin sparing effect. Theoretically, the dose on the skin in 60Co teletherapy is too small to give any observable skin reactions for routine therapeutic dose but the published reports indicate that in practice the skin reactions are much more than expected. The increased skin reactions are due to the increased dose on the skin because the gamma beam from 60Co gets contaminated by scattered electrons. Use of electron filters and increased distance between the source and the patient are two methods in use to reduce the electron contamination of the beam. Earlier studies with electron filters indicate that medium atomic number materials are best for this purpose. A new filter material - silver - has beem tried by us and its efficacy in reducing the surface dose has been studied. Loss of skin sparing of 60Co beam because of oblique incidence has also been reported. This arises from the geometric considerations of the direction of the scattered electrons in the tissue. This problem has also been studied and the role of a silver filter in such circumstances has also been investigated. The studies lead us to conclude that the medium Z materials, such as silver, are best under all treatment conditions. However, if the treatment field is small (10×10 cm2 or less) or the distance between the filter and the skin is more (25 cm or more), the filter materials in a wide range of atomic numbers are equally effective. The silver filter is also effective in reducing the increased surface dose due to oblique incidence of the beam. © 1979.
Epidemiological correlates between consumption of Indian chewing tobacco and oral cancer
(Kluwer Academic Publishers, 1990) M.L. Goud; S.C. Mohapatra; P. Mohapatra; S.D. Gaur; G.C. Pant; M.N. Knanna
The problem of cancer is universal; the only variation occurs in the type, site or other clinicoepidemiological parameters. Peculiarly enough, oral cancers caused by chewing tobacco are common in India and some parts of the Indian sub-continent. Oral cancers caused by other carcinogens are not common in these areas. The present study shows a significant association (P L 0.001) between the use of Indian chewing tobacco and oral cancer. Number of quids, mean quantity of tobacco and mean duration of keeping the quids in the mouth had direct dose and effect relationships in causation of oral cancer. A dose of 10 gms of chewing tobacco for about 26 years was observed to have produced cancerous lesions in the buccal cavity. © 1990 Gustav Fischer.
Erythrocyte survival studies in lymphomas: A prognostic appraisal
(1977) B. Sanyal; K. Subrahmanyam; G.C. Pant
Erythrocyte survival studies using Radioactive Chromium-51 were made in 20 lymphoma patients and 10 control subjects at the Centre of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi. Monitoring of the counts over hepatic, splenic and cardiac areas was done to detect hypersplenism. The normal T1/2 values ranged from 25-45 days with a mean of 35 days in our series. A majority of the patients with lymphomas showed reduced T1/2 values. The following observations could be made: (1) Patients with advanced disease (Stages III and IV) showed significantly reduced T1/2 values. (ii) None of the patients with the histologic varieties of L.P. and N.S. showed T1/2 values less than 20 days even in Stage III. (iii) Patients with M.C. even when in Stage II and with normal T1/2 values succumbed to the disease within 2 years. (iv) A majority of patients with L.D. were seen in Stage III and had T1/2 of 15 days and died within 2 years. (v) Low R.B.C. T1/2 values do not seem to have a bad prognostic significance in non-Hodgkin's lymphomas (period of observation 2 years 6 months). (vi) A significant correlation could be shown between R.B.C. T1/2 values and Hb%. Similarly, patients with normal or near normal T1/2 values had a higher A.E.C. compared to lower values observed in patients with low T1/2 values. This may be a reflection upon the diminishing immunologic status of the patients with advanced disease and R.B.C. T1/2. However, no significant correlation could be observed between T1/2 and A.L.C. In the final analysis, it appears that for Hodgkin's disease there is a good correlation between the stage of the disease, histologic variety, Hb%, T1/2 and survival status of the patients.
Ewing's sarcoma: A combined approach in the management
(1981) G.C. Pant; B. Sanyal; K. Sahni; S.M. Tuli; T.P. Srivastava
Twenty-seven histologically confirmed cases of localised Ewing's sarcoma were treated by two different regimes. Radiotherapy alone was used in 13 cases and a combination of chemotherapy and radiotherapy in 14. Single agent chemotherapy (cyclophosphamide) was given sequentially in nine patients and cyclophosphamide and actinomycin-D in five. There is a significant difference in the response to these different regimes. Only 69.2% of patients treated by radiotherapy alone were disease-free, for a median period of 10.4 months and metastases were noticed in 53.8% of cases. The disease-free survival in patients treated by combination therapy (radiotherapy and chemotherapy) was 18.4 months and metastases were seen in only 42.9%. However, no metastases were seen in patients who received cyclophosphamide and actinomycin-D, during a period of 14 months and only one patient showed residual disease. It is concluded that the addition of cyclophosphamide alone is not adequate in the management of Ewing's sarcoma. Actinomycin-D in addition to cyclophosphamide has improved the disease-free survival period significantly. The optimum dose of radiotherapy and its combination with other chemotherapeutic agents needs further trials to find the best and most suitable schedule. © 1981 Royal College of Radiologists.
Extramedullary plasmacytoma: Simulating a soft tissue sarcoma of the chest wall
(1980) B. Sanyal; G.C. Pant; K. Sahni; S. Khanna; R.M. Gupta; N.N. Khanna
Extramedullary plasmacytoma occurs infrequently as compared to osseous myoloma. A single case of extramedullary plasmacytoma was seen during the last 10 years whose initial presentation was that of a soft tissue sarcoma of the chest wall. Clinical data along with relevent investigation and treatment results are discussed with a review of the literature. Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company