Browsing by Author "Govind Narayan Srivastava"

Now showing 1 - 7 of 7

Association of Low body Mass Index with Respiratory Failure in Chronic Obstructive Pulmunary Disease
(NLM (Medline), 2021) Ritamvara Oli; Jai Krishna Mishra; Govind Narayan Srivastava; Saurabh Mishra
BACKGROUND: Various studies have shown that low body mass index co-relates with the severity of Chronic obstructive pulmonary disease. The reduced body mass index in these patients is thought to be due to nutritional abnormality and raised circulating inflammatory markers. The study is aimed to find the association of body mass index with respiratory failure in patient with chronic obstructive pulmunory disease. METHODS: 142 patients who attended emergency /out-patient-department in Sir Sundarlal Hospital from August 2018 to July 2020 were enrolled for the study. 81 patients in one group had chronic obstructive pulmonary disease exacerbation with Type II respiratory failure. Among this group low and normal body mass index subgroup was categorized.61 patients in another group had chronic obstructive pulmonary disease. Non-invasive ventilation was applied to case group. Categorization of body mass index was done <18.5(Low BMI) and 18.5-24.9 (Normal BMI ). RESULTS: The mean age of the study group was (63.53±9.021). There was a significant difference in the body mass index between the groups ( p=<0.001,t=15.40). Severity of respiratory failure was compared using ph and pco2 in the between the groups which showed no significant difference (p=1,chi square 0.000), (p=0.40,chi square=0.72) however it did affect the outcome. CONCLUSIONS: Our study shows that overall respiratory failure was common in low body mass index cases compared to Control. Nevertheless there was no difference among severity of respiratory failure among low and normal body mass index subgroups and however it did affect the outcome.
Clinical tools and biochemical markers to assess short-term mortality in acute exacerbation of chronic obstructive pulmonary disease (COPD)
(Journal of Clinical and Diagnostic Research, 2018) Govind Narayan Srivastava; Manoj Meena; Ankit Patel; Ashok Singh Charan; Mukesh Goyal; Piyush Arora; Ramniwas Meena
Introduction: Acute exacerbation of COPD is one of the leading causes of death worldwide. Aim: This study was aimed to study the role of clinical tools and biochemical markers which have significant impact on short-term mortality in COPD patients presenting with acute exacerbation. Material and Methods: A total of 50 patients were studied. Patients of age >40 years having COPD exacerbation and presenting with two of the three cardinal features of exacerbation: increase in amount of cough, increase in purulence of cough, increase in baseline dyspnoea which were severe enough to necessitate a hospital admission, were evaluated after admission. A thorough history taking and clinical examination was performed along with all necessary laboratory parameters were studied. Study population was followed for 30 days. Data was analysed using Chi-square test and multivariate regression analysis using SPSS version 16.0. Results: Out of 50 patients, 30% (15/50) did not survive despite treatment. Parameters such as, history of mechanical ventilation in past one year, low GCS (Glasgow Coma Scale), raised JVP (Juglar Venous Pressure), low pH and raised IL-6 levels were significantly associated with mortality in multivariate analysis (p-value <0.05). Conclusion: Severity of disease as well as severity of present exacerbation was related with short-term mortality. Interleukin-6 is an independent predictor of mortality. Parameters like past history of mechanical ventilation and raised JVP point towards the need of overall better management of COPD patients not only during exacerbations. © 2018, Journal of Clinical and Diagnostic Research. All rights reserved.
Illness perception in tuberculosis by implementation of the Brief Illness Perception Questionnaire – a TBNET study
(SpringerOpen, 2014) Dragica P Pesut; Bogdana N Bursuc; Milica V Bulajic; Ivan Solovic; Katarzyna Kruczak; Raquel Duarte; Adriana Sorete-Arbore; Marinela Raileanu; Irina Strambu; Ljudmila Nagorni-Obradovic; Tatjana Adzic; Zorica Lazic; Maria Zlatev-Ionescu; Sorokhaibam Bhagyabati; Irom Ibungo Singh; Govind Narayan Srivastava
How patients relate to the experience of their illness has a direct impact over their behavior. We aimed to assess illness perception in patients with pulmonary tuberculosis (TB) by means of the Brief Illness Perception Questionnaire (BIPQ) in correlation with patients’ demographic features and clinical TB score. Our observational questionnaire based study included series of consecutive TB patients enrolled in several countries from October 2008 to January 2011 with 167 valid questionnaires analyzed. Each BIPQ item assessed one dimension of illness perceptions like the consequences, timeline, personal control, treatment control, identity, coherence, emotional representation and concern. An open question referred to the main causes of TB in each patient’s opinion. The over-all BIPQ score (36.25 ± 11.054) was in concordance with the clinical TB score (p ≤ 0.001). TB patients believed in the treatment (the highest item-related score for treatment control) but were unsure about the illness identity. Illness understanding and the clinical TB score were negatively correlated (p < 0.01). Only 25% of the participants stated bacteria or TB contact as the first ranked cause of the illness. For routine clinical practice implementation of the BIPQ is convenient for obtaining fast and easy assessment of illness perception with potential utility in intervention design. This time saving effective personalized approach may improve communication with TB patients and contribute to better behavioral strategies in disease control. © 2014, Pesut et al.; licensee Springer.
Illness perception in tuberculosis by implementation of the Brief Illness Perception Questionnaire – a TBNET study
(Springer Verlag, 2014) Dragica P Pesut; Bogdana N Bursuc; Milica V Bulajic; Ivan Solovic; Katarzyna Kruczak; Raquel Duarte; Adriana Sorete-Arbore; Marinela Raileanu; Irina Strambu; Ljudmila Nagorni-Obradovic; Tatjana Adzic; Zorica Lazic; Maria Zlatev-Ionescu; Sorokhaibam Bhagyabati; Irom Ibungo Singh; Govind Narayan Srivastava
How patients relate to the experience of their illness has a direct impact over their behavior. We aimed to assess illness perception in patients with pulmonary tuberculosis (TB) by means of the Brief Illness Perception Questionnaire (BIPQ) in correlation with patients’ demographic features and clinical TB score.; Our observational questionnaire based study included series of consecutive TB patients enrolled in several countries from October 2008 to January 2011 with 167 valid questionnaires analyzed. Each BIPQ item assessed one dimension of illness perceptions like the consequences, timeline, personal control, treatment control, identity, coherence, emotional representation and concern. An open question referred to the main causes of TB in each patient’s opinion.; For routine clinical practice implementation of the BIPQ is convenient for obtaining fast and easy assessment of illness perception with potential utility in intervention design. This time saving effective personalized approach may improve communication with TB patients and contribute to better behavioral strategies in disease control.; The over-all BIPQ score (36.25 ± 11.054) was in concordance with the clinical TB score (p ≤ 0.001). TB patients believed in the treatment (the highest item-related score for treatment control) but were unsure about the illness identity. Illness understanding and the clinical TB score were negatively correlated (p < 0.01). Only 25% of the participants stated bacteria or TB contact as the first ranked cause of the illness. © 2014, Pesut et al.; licensee Springer.
Nocardia farcinica as a causative agent of lung abscess
(Wolters Kluwer Medknow Publications, 2015) Manoj Meena; Ramakant Dixit; Harish Sabarigirivasan; Govind Narayan Srivastava; Lalit Prashant Meena
[No abstract available]
Primary and acquired drug resistance patterns of Mycobacterium tuberculosis isolates in India: A multicenter study
(2013) Jitendra Prasad Mathuria; Jai Kumar Samaria; Govind Narayan Srivastava; Bharat Lal Mathuria; Sanjay Kumar Ojha; Shampa Anupurba
Tuberculosis is the most prevalent infection worldwide. The emergence of drug-resistant Mycobacterium tuberculosis (M. tuberculosis) isolates emphasizes that it is necessary to monitor drug resistance of the organism against anti-tubercular drugs. We analyzed 327 M. tuberculosis isolates from patients who were cared for at three different health care centers, hereinafter known as study areas (SAs), in North India. Of the 327 total M. tuberculosis isolates, 255 were from a tertiary health care center (Varanasi, Uttar Pradesh [SA-1]), 48 were from a District tuberculosis center (Sawai Madhopur, Rajasthan [SA-2]), and 24 were from a different District tuberculosis center (Buxar, Bihar [SA-3]). Drug susceptibility testing against first-line antibiotics (viz. isoniazid, rifampicin, streptomycin, and ethambutol) was conducted for all the isolates using 1% proportional method. We found that the rates of acquired resistance were consistently higher than the rates of initial drug resistance. In new, untreated cases, a higher degree of MDR-TB was observed at SA-1 (13.3%) and SA-3 (25.0%), whereas it was observed in only 7.1% of the isolates at SA-2. In previously treated patients, MDR cases were found in 35.7% of the isolates from SA-1, 66.6% of the isolates from SA-2, and 43.8% of the isolates from SA-3. Resistance to a single drug was found at a much lower rate, ranging from 0.0 to 6.3% in new cases as well as previously treated cases. In conclusion, the primary resistance of M. tuberculosis is low, but acquired drug resistance is slightly higher in North India. © 2013 King Saud Bin Abdulaziz University for Health Sciences.
Seven steps of gradual cessation of smoking--an example from India.
(2007) Govind Narayan Srivastava
BACGROUND/AIM: One sixth of smokers in the world live in India. The National Family Health Survey showed that individuals with no education were 2.69 times more likely to smoke and chew tobacco than those with postgraduate education. Whether the physicians' interaction with public can cause the smoking cessation or habit by detailing the harmful effects as well as benefits of cessation without any withdrawal effects? Our aim was, therefore, to help people to stop smoking step by step. METHODS: The study was conducted at the University Student Health Care Centre, Banaras Hindu University, Varanasi, India, from June 2004 to February 2005. A total of 1,200 students smokers (graduate, post graduate or research scholars) participated. They were from 17 to 32 years old (mean age, 26 years). All were male sex. Each and every student was explained in details risks and hazards, and benefits of cessation, focusing this latter on immediate and substantial benefits at any sex and age; their every question and quarries were explained. All were told that either they should stop smoking immediately or minimized step by step. The seven steps were explained to them. RESULTS: The smoking duration was one year and more in all the participants ranging from one to 15 years; the average period of smoking was five years and six months; the number of smoked cigarettes per day was 12 on average (5-20). In 450/1200 (37.50%) students, either of any family members were smoking while 200 (16.66%) students have been inspired from their friends. The majority of 780/1200 (65%) gave-up smoking at any step as advised. The followup could not be done in 80/1200 (6.6%) students who did not report at any of the stages. Finally, 340/1200 (28.0%) students either reduced the number or failed to give-up smoking. CONCLUSION: The results of the study are very encouraging. Such interaction type of doctors with smokers will not only help to the concerned person but also to the society.