Browsing by Author "Harish Shah"

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Pharmacognostic standardization of Asian folk medicinal plant Reinwardtia Indica Dumort
(BRNSS Publication Hub, 2018) Prabhat Upadhyay; Suresh Purohit; S.K. Mishra; K.N. Tiwari; G.P. Dubey; Harish Shah
Background: Recent scenario and global trends are moving toward the medicinal plant used as health-care product for the treatment of different disease or disorder, but the critical and essential issue to be considered in assuring the therapeutic efficacy and safety. Thus standardization of plant parts need to standardized according to the standard guideline for global acceptance of the product. Reinwardtia indica belongs to Linaceae family used as folk medicine in Asia in the treatment and management of boils, carbuncle, and as an antimicrobial agent in wound healing traditionally. Objective: The present study aimed at physicochemical standardization of R. indica leaves and stem part of the plant. Materials and Methods: In our investigation, leaves and stem part of R. indica were standardized based on microscopy, powder microscopy, physicochemical evaluations, extractive yields, and heavy metal analysis as per the International Regulatory Norms. Results: The results revealed that the pharmacognostic parameters have shown the leaves and stem part of the R. indica plant found within the standard limit as per regulatory norms. Conclusion: The data found after standardization can be adopted as a standard of the plant R. indica, and it can be used in the formulation of the health care product after pre-clinical and clinical investigations. © 2018 BRNSS Publication Hub. All rights reserved.
Phytochemistry and pharmacological activity of Mucuna pruriens: A review
(BRNSS Publication Hub, 2017) Mukesh Kumar Yadav; Prabhat Upadhyay; Suresh Purohit; B.L. Pandey; Harish Shah
The plant Mucuna pruriens (Fabaceae) is an established herbal drug, widely known as "velvet bean," a vigorous annual climbing legume originally from Southern China and Eastern India, where it was at one time widely cultivated as a green vegetable crop. It has been shown that its seeds are potentially of substantial medicinal importance. The ancient Indian medical system, Ayurveda, traditionally used M. pruriens, even to treat such things as Parkinson's disease. M. pruriens has been shown to have antiparkinson and neuroprotective effects, which may be related to its antioxidant activity and used for the management of male infertility, nervous disorders, and also as an aphrodisiac.