Browsing by Author "Harshitaa Aggarwal"

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Comparative evaluation of dual‑cure resin (TheraCal PT) and Biodentine in coronal pulpotomy of patients with symptoms indicative of irreversible pulpitis: A randomized clinical trial
(Wolters Kluwer Medknow Publications, 2024) Harakh Chand Baranwal; Neelam Mittal; Silviya Samad; Aiyman Ayubi; Harshitaa Aggarwal; Shubham M. Kharat
Background: New and innovative materials are being marketed for the treatment of coronal pulpotomy. It is crucial to compare their efficacy with already‑established materials. TheraCal PT (TP) is such a new material that studies are scarce. Aim: This study aim to compare and evaluate the outcome of coronal pulpotomy using Biodentine and a newly introduced calcium silicate‑based dual‑cure resin cement, TP, in patients with symptoms of irreversible pulpitis. Materials and Methods: Sixty patients with exposed carious pulp and symptomatic irreversible pulpitis were included, aged 18–40, randomly allocated to two groups: TP (group I) and Biodentine (group II). Coronal pulpotomy was performed following a standardized protocol, with TP or Biodentine applied accordingly. The pain was recorded using Visual Analog Scale preoperatively for up to 1 week. Success was assessed clinically and radiographically for up to 12 months. Statistical Analysis Used: The data were analyzed using the Friedman test and the Mann–Whitney U‑test. Intragroup pain was analyzed using the Wilcoxon signed‑rank test. Results: Among 60 patients, intervention was done in 53. By removing dropout patients, 47 were analyzed, with 38 available for follow‑up at 3, 6, and 12 months. The Biodentine group exhibited a 12‑month success rate of 84%, while the TP group revealed 77.3%, with statistically insignificant difference (P = 0.563). Conclusion: TP can be effectively utilized as a pulpotomy material in cases of symptomatic irreversible pulpitis in mature permanent teeth, offering rapid setting and ease of use, although Biodentine yielded slightly better results in this study. © 2024 Journal of Conservative Dentistry and Endodontics.
Comparative evaluation of quantitative color changes in discolored anterior teeth by bleaching, resin infiltration, and microabrasion: A randomized clinical trial
(Wolters Kluwer Medknow Publications, 2025) Neelam Mittal; Harakh Chand Baranwal; Shubham M. Kharat; Aiyman Ayubi; Silviya Samad; Harshitaa Aggarwal
Objective: This study aims to evaluate and compare the effects of bleaching, microabrasion, and resin infiltration (RI) techniques on discolored vital anterior teeth. Materials and Methods: Patients with anterior vital teeth with brown discolorations were selected for this study. The sample size was estimated at 15 teeth per group and assigned according to the treatment done: Group 1 (microabrasion), Group 2 (microabrasion and RI), Group 3 (microabrasion, bleaching, and RI), Group 4 (bleaching and RI), and Group 5 (bleaching). Standardized photographs were taken at the preoperative visit (T1), immediately after treatment (T2), and during the follow‑up visit after 1 week (T3), and at 6 months (T4). The photographs were analyzed using (L* a* b*) values with the help of Adobe Photoshop 2021 software to show the assessment of values. Respective values were used to evaluate a quantitative evaluation of color change (ΔE). Results: The highest value change (ΔE = 20.72 ± 3.06) was seen in Group 3 which was statistically significant, suggesting that microabrasion and bleaching followed by RI offer better results than the other groups. Conclusion: Combining microabrasion, bleaching, and RI techniques offers the best treatment outcome for tooth discolorations among all groups. © 2025 Journal of Conservative Dentistry and Endodontics | Published by Wolters Kluwer - Medknow.
Comparative evaluation of resin-based sealers and bioceramic sealers for postoperative pain after endodontic treatment: A systematic review
(Wroclaw University of Medicine, 2024) Neelam Mittal; Thivyashankari Thangamuthu; Supriya Gupta; Sakshi Gupta; Harshitaa Aggarwal; Shubham Kharat
The systematic review aimed to compare and evaluate the effect of resin-based sealers and bioceramic sealers on postoperative pain after endodontic treatment. Two reviewers independently conducted electronic search in PubMed, the Web of Science, ScienceDirect, the Wiley Online Library, SpringerLink, Google Scholar, and the Cochrane Library, employing a complete dual-review process to ensure the inclusion of all relevant studies in the review. The search was carried out until November 2021. After selecting eligible studies, the risk of bias assessment was carried out using the revised Cochrane risk-of-bias tool for randomized trials (RoB 2). A total of 1,931 studies were identified from the electronic search, and finally 10 studies were included after full-text assessment. In all our included studies, the visual analog scale (VAS) was used for recording pain scores. Most of the studies recorded pain intensity starting from 6 h to 7 days. The results showed that there was no significant difference between resin-based sealers and bioceramic sealers in terms of incidence or intensity of postoperative pain at any point in time. © 2024, Wroclaw University of Medicine. All rights reserved.
Comparison of double antibiotic chitosan hydrogel scaffold with platelet‑rich fibrin in regeneration in immature necrotic permanent teeth – Randomized controlled trial
(Wolters Kluwer Medknow Publications, 2024) Neelam Mittal; Harakh Chand Baranwal; Harshitaa Aggarwal; Shubham Kharat; Silviya Samad; Aiyman Ayubi
Background: Fibrin, a natural hydrogel, can act as scaffold for tissue regeneration. Antibiotic‑loading of hydrogels can create an infection‑free environment for stem cell proliferation and maturation. Aim: To compare regenerative endodontic potential of three groups (antibiotic‑loaded hydrogel, chitosan‑loaded hydrogel, and double antibiotic‑loaded chitosan hydrogel) in immature necrotic permanent teeth with platelet rich fibrin (PRF). Materials and Methods: Fifty‑six immature necrotic teeth with periapical lesions were included in simple randomized parallel‑controlled superiority trial. Patients aged 10–35 years were assigned into four groups based on scaffolds used: Group 1 (PRF), Group 2 (double antibiotic‑loaded [metronidazole and ciprofloxacin] chitosan hydrogel), Group 3 (double antibiotic‑loaded hydrogel), and Group 4 (chitosan‑loaded hydrogel). One patient per group was lost to follow‑up. Regenerative outcomes (change in apex size, root length, radicular dentin thickness, and periapical healing) were assessed at 12 months, through double‑blinding and compared postprocedure using cone‑beam computed tomography. Statistical Analysis: Based on normality distribution, change in apex size (ANOVA test) while root length, radicular dentin thickness (Kruskal–Wallis test), and periapical healing (paired t‑test) were used. Results: Group 2 showed superior regenerative outcomes (P = 0.001) compared to groups 1, 4 after 12 months, and no significant difference with Group 3. Conclusion: Double antibiotic‑loaded chitosan produced significantly superior outcomes compared to PRF in promoting apexogenesis in immature permanent teeth with necrosed pulp. © 2024 Journal of Conservative Dentistry and Endodontics.