Browsing by Author "K. Subrahmaniyam"

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Combined treatment modalities for intracranial tumours
(1978) B. Sanyal; G.C. Pant; K. Subrahmaniyam; K. Sahni; M.S. Agarwal; S. Mohanty; C.J. Rao; P.K. Shukla
[No abstract available]
Pregnancy complicated by cancer of the cervix: A study of 90 cases
(1977) K. Subrahmaniyam; G.C. Pant; B. Sanyal
Cancer of the cervix complicating pregnancy accounted for 4.7% of all cancers of the cervix. The patients in the present material were about 10 yr younger as compared to their Western counterparts. In contrast to Western reports on this subject, the majority of the patients were seen in the late stages of the disease. About 90% of the patients delivered via the natural route and no increased morbidity or mortality was noticed. A comparison of the results of treatment between the general (non pregnant) group and the cancer of the cervix in pregnancy group, in fact shows better 2 yr survival figures in favor of the latter. It is concluded that vaginal delivery is not harmful to the mother and does not adversely affect the prognosis in patients of cancer of the cervix with associated pregnancy.
Radiation myelopathy
(1979) B. Sanyal; G.C. Pant; K. Subrahmaniyam; M.S. Agrawal; S. Mohanty
Five cases of radiation myelopathy were found in a total of 10000 cases given radiotherapy from 1968 to 1977. The clinical presentation and treatment details including the total dose, treatment volume, number of fractionations, overall time, and the RET value at the spinal cord were calculated and compared with other reports on this subject. The total number of fractionations ranged from 20 to 26 with an overall time of 32 days to 37 days. The dose received by four patients ranged from 1030 to 1900 RET, a little higher than the tolerance level of the spinal cord as compared to reported values. Two patients in this series had high blood pressure. The incidence of radiation myelopathy, already acceptably low, could possibly be reduced further by meticulous planning of radiation.
Serum copper in patients in non-Hodgkin's lymphomas - a preliminary appraisal of its significance in management
(1979) K. Subrahmaniyam; B.N. Rao; P.K. Shukla
Serum copper level (SCL) estimations were done in 22 healthy adults and 15 patients in non-Hodgkin's lymphomas. Among healthy adults, females tended to have higher SCLs compared to males, though the difference was statistically not significant (P>0.05). The mean SCL in control subjects was 84.45 ug percent ± 28.02 with a range of 49-156 ug percent. Significant difference was noted between pre-treatment SCLs and SCLs in control subjects (P<0.01) and post-treatment SCLs (P 0.01). Pre-treatment SCLs in patients with Stage IV disease and in those with diffuse histologic patterns tended to be higher compared to the levels observed in patients with Stages I and II and nodular histologic patterns, but the observed differences were not statistically significant (P>0.05). Serial estimations of SCL during post-treatment follow-up period were valuable in judging therapeutic efficacy, remission status and to forecast a relapse before it actually occurred. A plea is made to adopt SCL estimations routinely in the management of patients with malignant lymphoma.