Browsing by Author "K.N. AGARWAL"

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CORD BLOOD HAEMOGLOBIN, IRON AND FERRITIN STATUS IN MATERNAL ANAEMIA
(1983) R.M.D. AGRAWAL; A.M. TRIPATHI; K.N. AGARWAL
ABSTRACT. Maternal and cord blood haemoglobin, serum iron, transferrin saturation and ferritin were studied in sets of 30 anaemic (haemoglobin <110 g/l) and 21 nonanaemic (haemoglobin ≧110 g/l) mothers. The cord serum iron, transferrin saturation and ferritin concentrations had significant correlation with maternal haemoglobin. The significant low levels of these parameters suggested that maternal anaemia adversely affected the iron status including iron stores of the newborns. The cord serum iron of 15.2±4.35 μmol/l and ferritin of 29.7±10.93 ng/ml seem to be effective to maintain cord haemoglobin levels. Thus, anaemic mothers with reasonably maintained ferritin and trasferrin saturation levels provide sufficient iron for maintenance of cord haemoglobin, although foetal iron stores are likely to be depleted. Copyright © 1983, Wiley Blackwell. All rights reserved
EFFECT OF INTRAUTERINE NUTRITIONAL DEPRIVATION ON NEUROMOTOR BEHAVIOUR OF THE NEWBORN
(1979) V.P. BHATIA; G.P. KATIYAR; K.N. AGARWAL
Abstract. The neurological maturation in 25 newborn babies born to severely undernourished mothers was studied by evaluating muscle tone and excitability status. These mothers had weight below the 25th percentile expected for height, haemoglobin less than 80.0 g/l and serum albumin less than 25.0 g/l. Twenty‐three babies born to healthy mothers were studied as control. The babies of undernourished mothers demonstrated gross intrauterine growth retardation. There occurred parallel reduction in placental weight and its protein content. The neuromotor behaviour of these newborns showed significant alteration in the performance of most reflexes, resembling normal motor behaviour of preterm infants. As many as 72% newborns could be classified as hypotonic and 56% hypoexcitable. However, no newborn demonstrated hypertonia or hyperexcitability. The parameters of neuromotor assessment were found to have no correlation with the birth weight in both undernourished as well as control groups. These observations suggest that muscle tone and excitability are better indices of maturation of central nervous system than the birth weight. It seems that the neurological evaluation becomes unreliable in babies who suffer from intrauterine nutritional deprivation. Copyright © 1979, Wiley Blackwell. All rights reserved
FAMILIAL ATAXIC DIPLEGIA
(1974) G. SUBRAHMANYAM; A.M. TRIPATHI; K.N. AGARWAL
Abstract. Subrahmanyam, G., Tripathi, A. M. and Agarwal, K. N. (Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India). Familial ataxic diplegia. Acta Paediatr Scand, 63: 472, 1974.–A family with ataxic diplegia, mental and physical growth retardation in two generations is presented. The disease was limited to male members, suggesting a sex‐linked transmission. Copyright © 1974, Wiley Blackwell. All rights reserved
Growth Pattern of Intrauterine Growth Retarded (IUGR) Babies in First Nine Months of Life
(1984) B.D. BHATIA; K.N. AGARWAL; N.P. JAIN; V. BHARGAVA
ABSTRACT. Forty‐one full term intrauterine growth retarded (IUGR) babies of different maternal etiologies viz. maternal undernutrition (12), small maternal size (12), toxaemia of pregnancy (9) and idiopathic (8) were studied for growth pattern during first 9 months of life. Eighteen fullterm and 11 preterm who were appropriate for gestational age served as controls. These mothers were comparable for age, parity, socioeconomic status, weight and height (except in small size mothers), haemoglobin and plasma albumin (except in undernourished group). The various anthropometric parameters studied were weight, crown‐heel length, head circumference, their velocities and ponderal index. The IUGR babies of undernourished mothers had lowest means for weight, crown‐heel length and skull circumference. The babies of small sized mothers suffered most in crown‐heel length followed by weight. The head growth was not affected in these babies. The IUGR babies of mothers with toxaemia of pregnancy demonstrated a catch up growth for all three parameters. The IUGR babies of idiopathic group showed a spurt in weight gain around 3 to 6 months and a similar spurt for crown heel length and head circumference was observed between 6 to 9 months of age. These babies were close to IUGR babies of mothers with toxaemia of pregnancy at 9 months. The preterm AGA babies also demonstrated a catch up growth for the weight, crown heel length and circumference. Copyright © 1984, Wiley Blackwell. All rights reserved
OEDEMA FLUID COMPOSITION IN CHILDHOOD DISORDERS
(1983) A.M. TRIPATHI; K.K. AGRAWAL; K.N. AGARWAL
ABSTRACT. Oedema fluid was collected from the leg through a sterile 21 gauge needle inserted into the subcutaneous space in 12 patients with protein energy malnutrition, 12 with nephrosis, 5 with Indian childhood cirrhosis, 4 with acute nephritis, 4 with epidemic dropsy and 3 with congestive heart failure. The concentrations of protein, free amino acids and electrolytes were measured in plasma and oedema fluid. The plasma/oedema fluid ratios were 36: 1, 49: 1, 32: 1 and 52: 1 in protein energy malnutrition, nephrosis, Indian childhood cirrhosis and congestive heart failure. These ratios were significantly smaller in epidemic dropsy (4: 1) and acute nephritis (21: 1). The free alpha amino nitrogen concentrations in these two compartments were almost in equilibrium. This was also found for essential and non‐essential amino acid distributions in protein energy malnutrition and nephrosis, whereas differences in amino acid patterns were found in nephritis and epidemic dropsy. Sodium and potassium concentrations varied substantially between diseases where the underlying cause was gross hypoproteinemia compared to non‐hypoproteinemic conditions. Copyright © 1983, Wiley Blackwell. All rights reserved