Browsing by Author "K.N. Udupa"

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131I profile scan in different human constitutions by whole body counter
(1978) G.P. Dubey; S. Agrawal; K.N. Udupa
[No abstract available]
A comparative study of urinary oestrogens in the cancer of breast and prostate
(1974) P. Kaul; G.C. Prasad; R.C. Gupta; K.N. Udupa
Estrogens have been estimated in 24 hr urine of breast cancer women during premenopausal and postmenopausal phases, before and after the surgery. There was an increased excretion of one of the fractions of estrogens, i.e. estriol as compared to the normals. There was not much change in the other two fractions, i.e. estrone and estradiol. With the advancement of the disease, there was an increased excretion of the urinary estrogens. Estrogen levels have also been observed in the patients suffering from carcinoma of prostate and a decrease in the urinary estrogen level was observed.
A comparative study on the effect of some individual yogic practices in normal persons
(1975) K.N. Udupa; R.H. Singh; R.M. Settiwar
[No abstract available]
A preliminary report on some physiological changes due to Vipashyana meditation
(1977) K.N. Dwivedi; V.M. Gupta; K.N. Udupa
A study of changes in blood pressure, pulse rate and respiration rate, conducted on volunteers attending a camp of Vipashyana Meditation in Varanasi, revealed the following: (i) Before attending the particular camp, subjects with previous meditation experience did not show significant changes in systolic blood pressure, pulse or respiration rate as compared to the control group of fresh students. However, diastolic blood pressure was found to be significantly lower (P<0.05) in persons with previous experience. (ii) After attending the particular camp of 10 days duration, there was a statistically significant reduction in their systolic (P<0.01) and diastolic blood pressure (P<0.01) and pulse (P<0.01) and respiration rate (P<0.001). It seems promising therefore to conduct in future properly designed extensive studies to evaluate physiological changes during meditation (by arterial cannulation), just after and long after meditation. The studies should also be extended to patients with hypertension and other psychosomatic ailments.
Adrenocortical response to surgery: changes in plasma cortisol (17-OHCS) levels
(1976) R.K. Singh; P.K. Dhar; J.P.N. Chansouria; K.N. Udupa
[No abstract available]
Adrenocortical response to surgery: changes in urinary corticoids and electrolyte levels
(1976) R.K. Singh; P.K. Dhar; J.P.N. Chansouria; K.N. Udupa
[No abstract available]
Alterations in acetylcholine, histamine and certain enzymes in peptic ulcer
(1980) N. Banu; J.P. Gupta; J.P.N. Chansouria; K.N. Udupa
In peptic ulcer patients the circulating levels of acetylcholine, histamine and monoamine oxidase are enhanced without any significant change in dopamine beta-hydroxylase activity. However, the acetylcholinesterase activity is considerably decreased. These observations tend to suggest over-activity of parasympathetic nervous system in this disorder. Thus, in addition to other factors, these biochemical changes may be of much significance in the causation of peptic ulcer.
Alterations in lipid metabolism following trauma in rabbits
(Birkhäuser-Verlag, 1973) J.P.N. Chansouria; A.K. Tandon; A.K. Singh; K.N. Udupa
[No abstract available]
Alterations in urinary VMA levels following cigarette smoking, coffee drinking and alcohol consumption
(1980) T.R. Sharma; J.P.N. Chansouria; K.N. Udupa
[No abstract available]
An evaluation of chemotherapy in disseminated malignancies
(1973) B.K. Kaul; K.N. Udupa
An evaluation of cyclophosphamide and mitomycin C in the treatment of diseminated malignancies is presented. While both of these chemotherapeutic agents seem to be equally good for malignant lymphomas, disseminated gastric cancers showed a marked regression only with mitomycin C. Liver and biliary cancers did not respond to any of these drugs. Leukopenia was not a feature in the majority of the patients.
Anti-fertility activity of a benzene extract of Hibiscus rosa-sinensis flowers on female albino rats
(1982) M.P. Singh; R.H. Singh; K.N. Udupa
[No abstract available]
Antiestrogenic activity of Hibiscus rosa sinensis Linn. flowers
(1976) S.D. Kholkute; K.N. Udupa
[No abstract available]
Arjunolitin, a triterpene glycoside from Terminalia arjuna
(1992) V.K. Tripathi; V.B. Pandey; K.N. Udupa; G. Rücker
Arjunolic acid diglycoside, which we have named arjunolitin, has earlier been reported from Terminalia arjuna. Its structure has now been established as 3-O-β-d-glycopyranosyl 2α,3β-23-tri-hydroxyolean-12-en-28-oic acid 28-O-β-d-glucopyranoside by chemical and spectral data. © 1992.
Ascorbic acid status of euthyroid patients
(1979) S.S. Dubey; R.P. Singh; K.N. Udupa
[No abstract available]
Ascorbic acid status of hyperthyroid patients
(1976) S.S. Dubey; R.P. Singh; K.N. Udupa
[No abstract available]
Ascorbic acid status of hyperthyroid patients
(1977) S.S. Dubey; R.P. Singh; K.N. Udupa
Controlled studies were conducted to find out the total, reduced and dehydroascorbic acid contents of plasma and thyroid tissue in hyperthyroid patients. Leucocyte ascorbic acid, urinary excretion of total ascorbic acid and ascorbic acid saturation tests were also carried out in order to assess the ascorbic acid status of these patients. It was observed that the plasma content of reduced ascorbic acid and total ascorbic acid were significantly subnormal in hyperthyroid patients whereas the dehydroascorbic acid was comparable with the control values. The urinary excretion of ascorbic acid was found to be lower than the control values. This indicates that in hyperthyroid patients the tissue status of ascorbic acid is poor. Thyroid tissue analysis also showed decreased levels of reduced and total ascorbic acid. However, the dehydroascorbic acid content was comparable with the control.
Autoradiographic studies on the role of adrenaline in stress by using H3 adrenaline
(1973) G.C. Prasad; M.Z. Siddiqui; K.N. Udupa
The site of action and the pathways of adrenaline after stress have been studied by using H3 labeled adrenaline. In this study the stress was induced in rats by producing fractures of the long bones and also by administering exogenous adrenaline in different doses. Animals were sacrificed at intervals of 15 min, 30 min, 1, 2, 4, 8, 12 and 24 hr after producing stress. All animals were injected with 25 microcuries of radioactive adrenaline intraperitoneally before the production of stress. After sacrificing the animals, the brain, all the endocrine glands, the heart, the liver and the kidney were subjected to microautoradiography. The authors localized the particular cells in the hypothalamus (PVN) which could be responsible for the endocrine and metabolic changes in the body after stress. The radioactive adrenaline granules could be seen in the various tissues at different intervals, including the thyroid gland, adrenal gland, heart muscle, liver, kidney, etc., suggesting the site of action of adrenaline on these tissues at different periods.
Biochemical basis of psychosomatic constitution
(1975) K.N. Udupa; R.H. Singh; G.P. Dubey; V. Rai; M.B. Singh
Eighty four apparently healthy normal males were psychosomatotyped following modified Sheldon's technique. Simultaneously, these volunteers were subjected to a biochemical determination of plasma diamine oxidase (DAO), plasma mono amine oxidase (MAO) and RBC cholinesterase (ChE). The final analysis of the data indicates a significant relative preponderance of DAO, MAO and ChE in Endo, Meso and Ecto morphs, respectively. As these enzymes have known parallelism with the respective neurohumors, namely acetylcholine, catecholamine and histamine, these biochemical types may be designated as histotrophic, vasotrophic and neurotrophics, respectively, in view of the specific functions of the three neurohumors.
Biogenic amines and thyrotoxicosis
(1992) L. Upadhyaya; J.K. Agrawal; G.B. Dubey; K.N. Udupa
Circulating levels of T3, T4, γ-amino-butyric acid, glutamate, 5-hydroxytryptamine, histamine, monoamine oxidase and histaminase were studied in 45 (25M, 20F) hyperthyroid patients and 46 (25M, 21F) normal healthy volunteers. Increased levels of blood 5-hydroxytryptamine, histamine and glutamic acid were observed along with elevated T3 and T4, whereas plasma γ-aminobutyric acid, monoamine oxidase and histaminase activities were found to be low in both male and female patients. After three months of treatment, circulating levels of 5-hydroxytryptamine, histamine and glutamic acid decreased significantly along with normalization of thyroid hormones and with an increase in the concentrations of γ-aminobutyric acid, monoamine oxidase and histaminase. There was a positive correlation between these amines and thyroid hormone levels. The findings thus suggest that alterations in the metabolism of biogenic amines may be related to an altered metabolism in thyrotoxicosis, and these parameters may prove to be useful markers for diagnosis and follow-up of these patients.
Blood and urinary biogenic amine levels in tuberculous meningitis
(1985) S.N. Rao; J.N. Singh; A.A. Singh; J.P. Chansouria; K.N. Udupa
The circulating levels of adrenaline, noradrenaline and serotonin were found to be significantly enhanced in patients of tuberculous meningitis. However, the urinary vanilmandelic acid and 5-hydroxyindoleacetic acid levels were not significantly altered in this condition. The elevated levels of biogenic amine in tuberculous meningitis could be attributed to the stress induced by disease itself. Repeated determination of these biogenic amines may also help in assessing the course and prognosis of this disease.