Browsing by Author "Kajal Manchanda"

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Allopurinol induced granuloma annulare in a patient of lepromatous leprosy
(2013) Satyendra Kumar Singh; Kajal Manchanda; Aakash Amar Bhayana; Anurag Verma
Granuloma annulare (GA) is a benign, inflammatory dermatosis involving dermis or subcutis with unknown etiology and poorly understood pathology. GA has characteristic histological features of necrobiosis, granuloma formation and abundant mucin deposition. Various predisposing factors, systemic diseases and drugs have been implicated in the etiology. We hereby describe a case of 70 year old male who was a known case of lepromatous leprosy, taking multidrug therapy for 6 months presented with multiple discrete, annular, firm, non tender, smooth surfaced skin colored papular lesions ranging in size from 0.5-1 cm over back for 1 month. There was past history of intake of allopurinol for hyperuricemia which was started 1 year back. There was history of similar lesions 6 months back which healed within 1 month of stopping allopurinol and he started taking the drug for the past 4 months on his own without any medical advice. Histopathological examination showed superficial and deep perivascular lymphocytic infiltrate with numerous histiocytes scattered in the intersititum of reticular dermis and abundant mucin in between the histiocytes. Allopurinol was implicated as an etiological agent and dramatic improvement was seen after stopping the drug for a period of 4 weeks. Naranjo's algorithm showed a probable association with a score of 6. Thus the final diagnosis of allopurinol induced generalised interstitial granuolma annulare was made. Patient was advised to continue antileprotic drugs, low purine diet and avoid allopurinol intake.
Annular alopecia areata: Report of two cases
(2013) Manish Bansal; Kajal Manchanda; S. Pandey
Alopecia areata (AA) is an auto-immune disorder characterized by the appearance of non-scarring bald patches affecting the hair bearing areas of the body. Scalp is the most common site of involvement. AA can affect any age group. The usual pattern of the hair loss is oval or round. We hereby, report two cases of annular and circinate pattern of AA due to its unusual morphology.
Basal cell nevus syndrome: A rare entity
(2012) Manish Bansal; Shri Nivash; Kajal Manchanda; Rahul Khanna
[No abstract available]
Brooke-Spiegler syndrome: A rare entity
(2012) Kajal Manchanda; Manish Bansal; Aakash Amar Bhayana; S.S. Pandey
Brooke-Spiegler syndrome (BSS) is a rare autosomal dominant disorder characterized by the presence of various adnexal tumors including multiple cylindromas, trichoepitheliomas and spiradenomas. A 35-year-old female presented with multiple asymptomatic nodular lesions over face and scalp since the age of 5 years. There were no complaints suggestive of systemic involvement. Her son, elder sister, younger sister, father, father′s sister, and grandmother had history of similar lesions. On examination, there were multiple asymptomatic skin-colored firm papulonodular lesions measuring from 2 to 8 mm in diameter, with smooth surface mainly affecting central part of face. Scalp showed pinkish, firm, smooth-surfaced, dome-shaped nodules measuring about 1 to 3 cm in size. Histopathological examination was consistent with trichoepitheliomas for the facial lesions and cylindromas for the scalp lesions. The diagnosis of BSS was thus confirmed.
Familial pityriasis rubra pilaris: A case report
(2013) Manish Bansal; Kajal Manchanda; Anurag; S.S. Pandey
Pityriasis rubra pilaris (PRP) is a rare papulosquamous disorder of unknown etiology characterized by reddish orange plaques with pityriasiform scaling with follicular keratoses, palmoplantar keratoderma, and occasionally erythroderma. We hereby report a family with five members affected with the condition in three successive generations.
Familial woolly hair: A rare entity
(2012) Satyendra Kumar Singh; Kajal Manchanda; Anand Kumar; Anurag VerM.A.
[No abstract available]
Hypohidrotic ectodermal dysplasia
(2012) Manish Bansal; Kajal Manchanda; Shyam Sunder Pandey
Ectodermal dysplasias (ED) are a group of inherited disorders characterized by dysplasia of structures of ectodermal origin, clinically classified into hypohidrotic and hidrotic forms. A 21-year-old female presented with history of hypohidrosis, thinning of scalp and eyebrow hair, xerotic skin, and periorbital and perioral wrinkling. There was hypodontia and peg-shaped teeth on intraoral examination. Routine investigations were normal, orthopantomogram revealed absence of multiple teeth with peg-shaped teeth. Histopathological examination showed thinned epidermis and reduction in the number of eccrine units. Thus, the diagnosis was confirmed as Hypohidrotic ED.
Multiple painful nodules in a segmental distribution in a middle-aged woman
(Wolters Kluwer Medknow Publications, 2014) Manish Bansal; Kajal Manchanda; Anurag Verma
[No abstract available]
Photodermdiagnosis linear growth over the thigh in a young girl
(2011) Manish Bansal; Kajal Manchanda; S.S. Pandey; Alka Bansal
[No abstract available]
Reactive perforating collagenosis in two siblings
(2013) Manish Bansal; Kajal Manchanda; Anand Kumar
[No abstract available]
Role of caffeine in the management of androgenetic alopecia
(2012) Manish Bansal; Kajal Manchanda; Shyam Sunder Pandey
[No abstract available]
Verrucous cell carcinoma arising from an underlying giant keratoacanthoma
(2012) Manish Bansal; Kajal Manchanda; Shyam Sunder Pandey
Keratoacanthoma is a well-known, fast-growing, benign squamous epithelial neoplasm that usually presents as a solitary, dome-shaped, pink or flesh-colored nodule developing a central keratin-filled crater. Few authors consider it to be a benign cutaneous tumor whereas others suggest that it should be regarded as a low-grade variant of cutaneous squamous cell carcinoma (SCC). A 21-year-old female presented with a firm, nontender, well-defined plaque with irregular margins measuring about 8 x 4 cm over the dorsal aspect of the right foot along with an exuberant growth from the plaque measuring 4 x 5cm. There was no lymphadenopathy. Systemic examination was within normal limits. Routine investigations, including complete blood counts, liver and renal function tests, urinalysis, chest radiographs, and abdominal ultrasonography, were normal. Histopathological examination of a skin biopsy from the plaque showed features suggestive of keratoacanthoma, whereas exuberant growth overlying the plaque showed features of verrucous carcinoma (a variant of SCC). Thus, it represents a case of SCC arising from a giant keratoacanthoma. © The Author(s) 2012.
What is your diagnosis?: Multiple asymptomatic nodules over the body with severe arthritis in a middle aged female
(Indian Rheumatology Association, 2012) Manish Bansal; Kajal Manchanda; Tulika Rai; Shyam Sunder Pandey; N.K. Singh
Thirty five year old female presented with severe joint pain involving knees, elbows, wrists, small joints of hands and lumbosacral spine for 3 years along with multiple skin colored, asymptomatic nodules scattered over her body for last 6 months. On examination, there were multiple discrete but grouped, firm, skin colored, non tender papules and nodules, ranging in size from 2 mm to 2 cm over multiple sites mainly involving trunk and bilateral upper limbs. Systemic examination was within normal limits. Routine blood investigations were normal except for raised Erythrocyte sedimentation rate (31 mm/h). Radiographs of bilateral hands showed erosive arthritis in left index, left middle, right index and right little finger. Punch biopsy from a nodule over dorsum of hand on histopathological examination showed circumscribed large focus of diffuse dense infiltrate of large histiocytes and histiocytic giant cells with the scattering of lymphocytes and few neutrophils. Thus the diagnosis of Multicentric Reticulohistiocytosis was confirmed. The patient was started on 30 mg prednisolone with 15 mg of methotrexate orally once a week. The patient noticed improvement in the joint symptoms but there was no improvement in cutaneous lesions. © 2012, Indian Rheumatology Association. All rights reserved.