Browsing by Author "Kamlesh Kumar Gupta"

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Awareness and outcome of changing trends in clinical profile of dengue fever: A retrospective analysis of dengue epidemic from january to december 2014 at a tertiary care hospital
(Journal of Association of Physicians of India, 2017) Jitendra Singh; Anju Dinkar; Virendra Atam; D. Himanshu; Kamlesh Kumar Gupta; Kauser Usman; Ravi Misra
Background: Dengue fever is caused by mosquito-borne arboviral infection that has become a public health concern globally. Recently, an alarming rise of dengue has also been seen in India. Hence the study was undertaken to know profile of clinical manifestations and laboratory findings during the evolution of dengue fever. Methods: In this study, retrospective data analysis was done in 216 seropositive dengue patients admitted between January to December 2014 in department of medicine at a north Indian care hospital. The tests analyzed were blood counts, serum electrolytes, liver function tests, kidney function tests, chest x-ray and other relevant investigations. Results: Males were commonly affected and the most exposed age group was found to be18-35 years. The seropositive case rate for dengue was 56% for NS1 antigen and 36% for IgM. There was rural dominancy of cases with a peak in September. Fever was the most common clinical feature followed by headache, myalgia, backache, nausea and abdominal pain. Petechia was most common haemorrhagic manifestation. Common laboratory findings included 89.35% decreased Platelet counts (<100 000/ cmm), 67.59% increased hematocrit (>45%) and 58.33% deranged liver function test. There was no reported mortality in dengue. Conclusions: From prompt and proper treatment could prevent deaths in moderate and severe dengue. Atypical presentations of dengue should be kept in mind so as not to miss the cases. Increased community awareness and vector control measures need to be strengthened during peri-monsoon period to reduce burden of dengue cases. © 2017, Journal of Association of Physicians of India. All rights reserved.
Meningitis with digital gangrene in meningococcal infection: An atypical presentation
(Journal of Clinical and Diagnostic Research, 2016) Jitendra Singh; Dandu Himanshu; Ranjit Kumar Nim; Anju Dinkar; Kamlesh Kumar Gupta
Meningococcal infection is an important public health concern. Neisseria meningitidis usually colonizes the nasopharynx of healthy adolescents and adults and remains as asymptomatic colonizer, while in rare cases it may present as invasive disease as either meningitis or septicemia or both. Most of the cases have typical presentation of rashes. We hereby present a case of a 40-year-old male who presented with meningococcal meningitis and peripheral digital gangrene but without development of typical rashes. He improved by early institution of appropriate intravenous antibiotics with supportive care. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.