Browsing by Author "Kuldeep Kumar Maurya"

Now showing 1 - 1 of 1

Liquid-assisted grinding (LAG) approach, metal-free synthesis of 2,3-dihydro-1,5-benzothiazepines and their electrochemical properties
(CSIRO, 2024) Manjit Singh; Kuldeep Kumar Maurya; Manisha Malviya
In this work, we have disclosed a facile metal-free synthesis of pharmaceutically fascinating and biologically important benzothiazepines in the presence of a few drops of ethanol. The present methodology converts chalcones and ortho-amino thiophenol into 2,3-dihydro-1,5-benzothiazepines under ambient conditions using liquid-assisted grinding, resulting in rapid synthesis in a very short period. This process is eco-friendly, operationally simple and gives good to excellent yields of products with easy isolation. This approach offers a facile synthesis of 2,3-dihydro-1,5-benzothiazepines from three readily available starting materials. An electrochemical study of the benzothiazepine derivatives was undertaken using cyclic voltammetry and electrochemical impedance spectroscopy techniques. © 2024 CSIRO. All rights reserved.