Browsing by Author "M. Kumar"

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A class of estimators for assessing the population mean under non-response using auxiliary information
(2012) M.K. Chaudhary; R. Singh; M. Kumar; A. Kr. Singh; A.A. Adewara
Khoshnevisan and some researchers in 2007 proposed a general family ofestimators for assessing the population mean of the variable under study. In this paper, their estimator is studied in the presence of non-response. An empirical study was carried out to demonstrate the performance of the suggested estimator and it was found that the empirical results supported the theoretical study.
A clinico-pathological study of meibomian gland carcinoma
(1997) R.P. Maurya; R.P. Bhatia; V. Thakur; O.P.S. Maurya; M. Kumar
Meibomian gland carcinoma of the eyelid is an uncommon neoplasm, representing less than 1% of all eyelid tumors.' It is relatively slow growing and clinically mimics benign lid conditions specially chalazion. This study includes nine cases of histologically proven meibomian gland carcinoma, where an attempt has been made to identify the clinicopathological correlation, prognostic factors, and the mode and result of treatment.
A trial to determine the role of placental extract in the treatment of chronic non-healing wounds.
(2004) V.K. Shukla; M.A. Rasheed; M. Kumar; S.K. Gupta; S.S. Pandey
OBJECTIVE: To investigate the effect of topical placental extract in the treatment of non-healing wounds. METHOD: One hundred patients attending the wound clinic at University Hospital, Varanasi, India, with wounds of more than six weeks' duration were recruited. Fifty patients were treated with placental extract, and 50 were controls. Wound biopsy and swab culture and sensitivity were performed and the area surrounding the wound was X-rayed. Wound size was measured and the rate of epithelialisation assessed at weekly follow-ups. In nine cases biopsies were repeated after two weeks of treatment and sent for histopathological examination, including angiogenesis. RESULTS: Thirty patients dropped out, leaving 40 cases in the treatment group and 30 in the control group. Over an eight-week period, 27 patients (67.5%) in the treatment group showed more than 50% epithelialisation, compared with only seven patients (23.3%) in the control group. CONCLUSION: Placental extract has a beneficial role to play as a topical agent in the management of chronic non-healing wounds.
Ab initio determination of molecular geometries and vibrational frequencies of CX3 COOH (X = H, F, Cl, Br)
(2008) R.A. Yadav; M. Kumar; R. Singh; P. Singh; S. Jaiswal; G. Srivastav; R.L. Prasad
Using Gaussian 03 Revision C.02 version of the quantum chemical program ab initio and DFT computations have been carried out at the rhf/6-31+g*, b3lyp/6-31+g*, b3lyp/6-31++g** and b3lyp/6-311++g** levels to compute optimized geometries, harmonic vibrational frequencies along with intensities in IR and Raman spectra and atomic charges for the acetic (ethanoic) acid and its 1,1,1-tri-halo (fluoro, chloro and bromo) derivatives. The optimized molecular structures for all the four molecules are found to possess Cs point group symmetry. The symmetric stretching mode is found to have lowest magnitude of the three CX3 stretching modes for all the four molecules, whereas the symmetric deformation mode is found to have the lowest magnitude for EA and TFEA and the highest magnitude for TCEA and TBEA. The parallel rocking mode of the CX3 group is found to have lower magnitude than the perpendicular rocking mode for EA and TFEA where reverse is found for TCEA and TBEA. The modes of the COOH group are substituent sensitive except the OH stretching mode. Moreover, the maximum effect is found for the TFEA molecule. The CF3 group is found to have the characteristic frequencies as 235-505, 787, 1150-1190 and 1400 cm-1 which are due to the modes δs(CF3), νs(CF3), νas(CF3) and ν(C-CF3), respectively. © 2008 Elsevier B.V. All rights reserved.
Ab initio studies of molecular structures, conformers and vibrational spectra of heterocyclic organics: I. Nicotinamide and its N-oxide
(2010) M. Kumar; S. Jaiswal; R. Singh; G. Srivastav; P. Singh; T.N. Yadav; R.A. Yadav
FTIR spectra of nicotinamide and its N-oxide have been recorded and analyzed in the range 400-4000 cm-1. The stabilities, optimized molecular geometries, APT charges and vibrational characteristics for the two possible conformers of nicotinamide and its N-oxide have been studied theoretically using restricted Hartree-Fock (RHF) and density functional theory (DFT) methods. The E (trans) conformers of nicotinamide and its N-oxide are found to be more stable and less polar than their respective Z (cis) conformers. Due to addition of an O atom at the N1 site in the NA molecule the magnitudes of atomic charges on all the H atomic sites are found to increase. For all the studied molecules, magnitude of the wagging mode of the NH2 group is found to be higher than its torsion mode, which is in the reverse order as compared to that for the aniline molecule. Most of the vibrational frequencies have nearly the same magnitude for the two conformers of nicotinamide and its N-oxide, however, significant changes are noticed in their IR intensities, Raman activities and depolarization ratios of the Raman bands. The frequency of the ring breathing mode for the NA molecule is found to decrease by 100 cm-1 in going to the NANO molecule for both the conformers. The IR intensity for the scissoring mode of the CON(H2) group is found to decrease significantly for the NA-II conformer as compared to that for the NA-I conformer. © 2009 Elsevier B.V. All rights reserved.
Abrasive wear characteristics of carbon and low alloy steels for better performance of farm implements
(Chinese Soc of Metals, 1995) M. Kumar; R.C. Gupta
The low stress abrasion behaviours of heat treated mild, medium carbon and high C-low Cr steels, which are generally used in making farm implements, have been investigated. The simple heat treatment greatly improves the hardness, tensile strength and abrasion resistance of medium carbon and high C-low Cr steels. The results indicate that the material removal during abrasion is controlled by a number of factors, such as hardness, chemical composition, microstructure and heat treatment conditions. The conclusion is that the heat treated high C-low Cr steel and mild steel carburized by coal-tar pitch provide the best hardness and abrasion resistance and thus appear to be the most suitable materials for making farm tools.
Acanthomatous ameloblastoma of anterior maxilla
(2010) M. Bansal; T.P. Chaturvedi; R. Bansal; M. Kumar
The unusual case of acanthomatous ameloblastoma occurring in maxillary left anterior region in a 13-year-old female child is presented with chief complaint of swelling in the upper left anterior region since one year and spacing between maxillary left central incisor and canine. Microscopic examination of surgically excised specimen revealed solid epithelial cell nests with peripheral palisading ameloblastic cells and the central squamous cell assemblage that was consistent with the findings of acanthomatous ameloblastoma type. Acanthomatous ameloblastoma is the extremely rare variant. The present report discusses issues related to the incidence of such formations in the target tissues.
Aerosol, climate, and sustainability
(Elsevier, 2017) T. Banerjee; M. Kumar; N. Singh
Aerosols, a typical multicomponent mixture originating from varying sources, potentially modify the physiochemical properties of atmosphere and thereby induce modifications in insolation, lower tropospheric heating, changes in atmospheric thermal structure, and interruption in circulation systems that both directly and indirectly link it with sustainability of the environment. Among many driving forces, aerosols are continuing to pose largest uncertainties in terms of understanding and quantifying Earth’s energy budget and thereby, its implications to climate change. To address the possible repercussions of aerosols-induced climate change on human and ecological sustainability, improved understanding and implementation both in terms of science and policy-level are required. © 2018 Elsevier Inc. All rights reserved.
Aerosol, Climate, and Sustainability
(Elsevier, 2017) T. Banerjee; M. Kumar; N. Singh
Aerosols, a typical multicomponent mixture originating from varying sources, potentially modify the physiochemical properties of atmosphere and thereby induce modifications in insolation, lower tropospheric heating, changes in atmospheric thermal structure, and interruption in circulation systems that both directly and indirectly link it with sustainability of the environment. Among many driving forces, aerosols are continuing to pose largest uncertainties in terms of understanding and quantifying Earth's energy budget and thereby, its implications to climate change. To address the possible repercussions of aerosols-induced climate change on human and ecological sustainability, improved understanding and implementation both in terms of science and policy-level are required. © 2018 Elsevier Inc. All rights reserved.
Airing ‘clean air’ in Clean India Mission
(Springer Verlag, 2017) T. Banerjee; M. Kumar; R.K. Mall; R.S. Singh
The submission explores the possibility of a policy revision for considering clean air quality in recently launched nationwide campaign, Clean India Mission (CIM). Despite of several efforts for improving availability of clean household energy and sanitation facilities, situation remain still depressing as almost half of global population lacks access to clean energy and proper sanitation. Globally, at least 2.5 billion people do not have access to basic sanitation facilities. There are also evidences of 7 million premature deaths by air pollution in year 2012. The situation is even more disastrous for India especially in rural areas. Although, India has reasonably progressed in developing sanitary facilities and disseminating clean fuel to its urban households, the situation in rural areas is still miserable and needs to be reviewed. Several policy interventions and campaigns were made to improve the scenario but outcomes were remarkably poor. Indian census revealed a mere 31% sanitation coverage (in 2011) compared to 22% in 2001 while 60% of population (700 million) still use solid biofuels and traditional cook stoves for household cooking. Further, last decade (2001–2011) witnessed the progress decelerating down with rural households without sanitation facilities increased by 8.3 million while minimum progress has been made in conversion of conventional to modern fuels. To revamp the sanitation coverage, an overambitious nationwide campaign CIM was initiated in 2014 and present submission explores the possibility of including ‘clean air’ considerations within it. The article draws evidence from literatures on scenarios of rural sanitation, energy practises, pollution induced mortality and climatic impacts of air pollution. This subsequently hypothesised with possible modification in available technologies, dissemination modes, financing and implementation for integration of CIM with ‘clean air’ so that access to both sanitation and clean household energy may be effectively addressed. © 2016, Springer-Verlag Berlin Heidelberg.
An improved estimator for the population mean using additional information
(2012) M. Kumar; R. Singh; A.A. Adewara
An improved estimator that made use of information on auxiliary variables and variables of interest which was not drawn up yet was proposed to estimate the population mean of the variable under study. Under simple random sampling without replacement, the mean square error up to the first order of approximation was derived. An empirical study was also carried out to show the properties and efficiency of the proposed estimator.
Angiogenesis and histologic scoring in prostatic carcinoma - A valuable cost effective prognostic indicator
(2004) M. Kumar; V. Tandon; P.B. Singh; S. Mitra; N. Vyas
Objective: To find any correlation between microscopic angiogenesis grading system (MAGS) score and Gleason score and serum prostate specific antigen (S.PSA) in carcinoma of prostate. Study design: Examination of 30 patients with prostatic carcinoma compared with an age matched control group of 30 patients having histopathologically proven benign prostatic Hyperplasia. The Preoperative serum PSA level was determined in all patients. Histopathological examination for MAGS score was done in all patients and Gleason scoring was done for cases of prostatic carcinoma. Result: MAGS score had a definite correlation with Gleason score (Correlation coefficient, r = 0.84, p = 0.008). Studying the relationship between MAGS score and S.PSA, a statistically significant difference is found between S.PSA levels in study and control groups, and in the three MAGS score groups namely 21-30, 31-40 and 41-50. Conclusion: Gleason score and MAGS score are well related to each other. As tumor becomes more poorly differentiated with rising Gleason score, it would also have increased number of capillaries and higher grade endothelial cytology leading to a higher MAGS score.
Assessment of chemically characterised Abelmoschus moschatus medik. Seed essential oil as shelf life enhancer of herbal raw materials based on antifungal, antiaflatoxigenic and antioxidant efficacy
(Taylor and Francis Ltd., 2017) A.K. Dwivedy; M. Kumar; A. Kedia; P.K. Mishra; C.S. Chanotiya; N.K. Dubey
The study reports fungal biodeterioration of herbal raw materials of Adhatoda vasica Nees and Withania somnifera Dunal and assessment of Abelmoschus moschatus Medik seed essential oil (AMEO) as antifungal, antiaflatoxigenic, and antioxidant. Seven fungal species belonging to three genera were isolated from Adhatoda vasica leaves and Withania somnifera roots. The minimum inhibitory, fungicidal, and aflatoxin inhibitory concentrations of AMEO were found to be 1750, 5000, and 1250 ppm, respectively, against A. flavus LHP-WS-1, isolated from W. somnifera. The effect of AMEO over ergosterol content in the plasma membrane was assessed to test the mode of action on A. flavus. AMEO also exhibited broad fungitoxicity at its minimum inhibitory concentration (MIC) and strong antioxidant property through 2,2-diphenyl-1-picrylhydrazyl (DPPH) analysis having IC50 value equal to 0.325 μL/mL. In view of strong antifungal, antiaflatoxigenic, and antioxidant activity, the AMEO may be recommended as botanical preservative for herbal raw materials in order to enhance their shelf life and to maintain their quality. © 2016 Societa Botanica Italiana.
Associating airborne particulates and human health: Exploring possibilities: Comment on: Kim, Ki-Hyun, Kabir, E. and Kabir, S. 2015. A review on the human health impact of airborne particulate matter. Environment International 74 (2015) 136–143
(Elsevier Ltd, 2015) M. Kumar; R.S. Singh; T. Banerjee
[No abstract available]
Asymmetric fission around lead: The case of Po 198
(American Physical Society, 2019) Shilpi Gupta; C. Schmitt; K. Mahata; A. Shrivastava; P. Sugathan; A. Jhingan; K.S. Golda; N. Saneesh; M. Kumar; G. Kaur; L. Stuttgé; D. Arora; H. Arora; A. Chatterjee; K. Chauhan; S.K. Duggi; D.P. Kaur; V. Mishra; Prashant N. Patil; K. Rani
Asymmetric low-energy fission of neutron-deficient nuclei around lead is addressed with the measurement of fragment mass and total kinetic energy properties for the fissioning system Po198 produced in heavy-ion fusion. Interpretation of the measurement for such a transitional nucleus at finite excitation energy is challenging. The presence of asymmetric partitions is suggested by the observed weak dependence of the total kinetic energy on mass and by the nonmonotonic evolution of the fragment-mass distribution width with excitation energy. The interpretation is supported by microscopic model calculations as well as by the results of an advanced semiempirical code. Combined with previous experiments in the region, the present measurement contributes to establish the evolution of the fragment-mass distribution as a function of the fissioning system. The connection between the "new" and the "old" islands of asymmetric fission is discussed. © 2019 American Physical Society.
Benign recurrent intrahepatic cholestasis
(The Indian Journal of Pediatrics, 2005) V. Gupta; M. Kumar; B.D. Bhatia
Benign recurrent intrahepatic cholestasis (BRIC) is a rare cause of cholestasis in children. The disease may start in infancy or early childhood. Jaundice persists or recurs throughout life but does not lead to chronic liver disease or cirrhosis. Treatment is mostly symptomatic. The condition has not been reported in Indian children. We report an interesting case of BRIC in a 9-year-old boy who had recurrent episodes of jaundice since when he was 1 yr old.
Carcinoma of the rectum in children
(1996) S.P. Sahoo; A.N. Gangopadhyay; D.K. Gupta; S.C. Gopal; C.K. Sinha; S. Gupta; M. Kumar
Two cases of carcinoma of the rectum in children (10 and 11 years old) are presented. Both cases presented as acute intestinal obstruction with the history of bleeding per rectum, constipation, abdominal distention, and loss of weight and appetite. Carcinoma of the colon and rectum in children is rare. Its clinical, pathologic, and biological characteristics are different than those of adults. The prognosis is poorer in children, the reason for which is explained, and its management is briefly discussed.
Clinicopathological profile and therapeutic appraisals in lymphoma in eastern Uttar Pradesh
(1997) V.P. Singh; S. Sundar; S. Gupta; B.L. Rastogi; M. Kumar; G.C. Pant; A. Jain; N. Gera
Ninety-four patients of lymphoma (55 of Non-Hodgkin's and 39 of Hodgkin's) were evaluated for clinical profile, histological subtypes and therapeutic outcome. Out of 94, 'B' symptoms were present in 66, lymphadenopathy in 82 and anaemia in 50 patients. Forty-three patients presented in stage IV. Mixed cellularity (53.8%) was the most common histologic subtype in Hodgkin's disease and diffuse mixed (30.5%) in non-Hodgkin's lymphoma. Initial complete remission rates as seen with chemotherapeutic regimes were 74.1% with COPP in Hodgkin's disease and 58.3% with CVP and 75% with CHOP in non-Hodgkin's lymphoma.
Comparative structural and vibrational studies of 6-amino purine (Guanine) and its radical species using density functional theory
(2011) Rashmi Singh; M. Kumar; P. Singh; R.A. Yadav
Guanine (G) is one of the most important nucleic acid bases (NAB) occurring in both DNA and RNA. In addition to being the largest NAB, it has also the most complex tautomeric equilibria. It is very important to understand the properties of the guanine base of DNA as thoroughly as possible since it is the most frequently involved site in the processes of mutation and cancer. The equilibrium geometries, APT charges, fundamental vibrational frequencies along with their corresponding intensities in IR spectrum, Raman activities and depolarization ratios of the Raman bands for the neutral and its radical species (G, G +, G -) of the guanine molecule were computed by density functional B3LYP method with 6-311++G (d, p) basis sets using Gaussian- 03 software. The thermodynamic functions of the title compounds were also performed at the same basis sets. The calculations predicted the G molecule as well as the radical anionic species of G to possess planar structures with C1 point group symmetry whereas the radical cationic species of G possesses Cs point group symmetry. The properties of the radical cations that are generated from the neutral neleobase molecules during the certain processes helps in understanding the nuclei acids in different environments and conditions. The radical anions are intermediates in a numbers of chemical reactions. Therefore data of their structures are useful for studying the mechanism and kinetics.
Correlation between AgNOR count and subjective AgNOR pattern assessment score in cytology and histology of breast lumps
(2001) A.K. Khanna; M.A. Ansari; M. Kumar; A. Khanna
OBJECTIVE: To find the correlation of argyrophilic nucleolar organizer region (AgNOR) count and subjective AgNOR pattern assessment (SAPA) score in cytology and histology of breast lumps. STUDY DESIGN: The study group consisted of 73 patients (46 malignant, 27 benign) with breast lumps. In all cases, fine needle aspiration cytology (FNAC) samples and histologic specimens were studied by conventional and silver staining for AgNORs. RESULTS: AgNOR count and SAPA score were helpful in differentiating benign from malignant tumors in both the cytologic smear and histologic specimen. AgNOR count was 6.94±2.74 in FNAC and 6.57±2.73 in histology of malignant tumors, while in benign tumors it was 2.75 ± 0.74 in FNAC and 2.68±0.77 in histology. SAPA score was 9.02±4.60 in FNAC and 8.76±2.34 in histology in malignant tumors and 5.87±0.93 in FNAC and 5.82± 0.83 in histology in benign tumors. CONCLUSION: Both AgNOR count and SAPA score gave similar results, but SAPA score is a more convenient, reproducible and rapid method of AgNOR evaluation.