Browsing by Author "M.K. Agarwal"

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A clinical study of the interrelationship between sinus disease and lower respiratory tract infections
(1980) H.C. Samant; B.K. Samanta; M.K. Agarwal
The present study was conducted on 147 patients in two groups, the first group comprising 61 patients with primarily lower respiratory tract infections, such as chronic bronchitis, bronchiectasis, bronchial asthma, lung abscess and pulmonary tuberculosis, and the second group consisting of 86 patients with predominantly naso-sinal involvement, including 70 cases of chronic sinusitis and 16 cases of allergic rhinitis. In the first group, the maximum number of cases (32.7%) were in the age group between 31 and 40 yr, while in the second group the highest age incidence (38.3% cases) was in the age group of 21-30 yr. Males predominated females in both the groups. Both the groups of patients showed presence of anaemia, a factor responsible for the causation and chronicity of sinorespiratory infections. Chronic bronchitis and bronchial asthma were common in both the groups. Sinusitis was found in 28 patients out of 61 cases of lower respiratory diseases. The incidence of sinusitis in bronchial asthma was found to be 57%. Maxillary sinus was commonly involved in 892.% of the cases. In the second group of patients with naso-sinal infection, only 12 cases (13.9%) revealed lower respiratory diseases, such as chronic bronchitis, bronchial asthma and tropical pulmonary eosinophilia. The presence of respiratory symptoms, such as cough and expectoration, dyspnoea and pain in the chest, in cases of naso-sinal infection, should suggest concomitant lower respiratory tract involvement.
A study of otorhinolaryngological manifestations in patients of chronic renal failure
(1997) M.K. Agarwal
The present study was carried out on 50 patients of Chronic renal failure (CRF), Majority of CRF patients had high frequency hearing loss, but inner ear changes were found to be irreversible even after dialysis. All cases had cochlear lesion. No relationship could be established between the level of blood urea, creatinine, serum potassium, serum calcium and blood pressure with the severity of the impaired hearing. A direct correlation was seen between increasing hyponatraemia and impaired hearing. No direct relationship could be made between blood pressure and epistaxis, but all the cases had raised blood urea. © 1997 Association of Otolaryngologists of India.
Aspergillosis of the maxillary sinus
(Springer India, 1998) M.K. Agarwal; P.K. Shukla
A rare case of aspergillosis of the maxillary sinus is reported. Surgical excision including the lining of the infected sinus is the preferred method of treatment. Antiimmunotherapy does not seem to affect the prognosis of this disease.
Cell mediated and humoral immunity in chronic suppurative otitis media
(1995) M.K. Agarwal; S.P. Rai; R.M. Gupta
The present study was carried out on 75 patients suffering from chronic otitis media and 25 healthy age and sex matched controls. The T. rosette percentage were depressed in malnourished pretreatment test cases and showed depressed cell mediated immunity (CMI), but once malnutrition was treated the CMI was improved. Anergy to challenge dose of 2:4 DNCB was not observed in any groups. Weak response was observed in 4% of controls, 18.7% of chronic otitis media patients and 5.7% of post treatment cases. Serum IgG, IgA and IgM levels were elevated in chronic otitis media patients from controls but once the infections were eliminated by treatment their values became insignificant (p 0.05) from controls. Presence of malnutrition significantly contributed to suppression of CMI response but no suppression of humoral immunity was observed. © 1995 Association of Otolaryngologists of India.
Cell mediated and humoral immunity in chronic suppurative otitis media
(1994) M.K. Agarwal; S.P. Rai; R.M. Gupta
The present study was carried out on 75 patients suffering from chronic otitis media and 25 healthy age and sex matched controls. The T. rosette percentage were depressed in malnouirished immunity (CMI), but once malnutrition was treated the CMI was improved. Anergy to challenge does of 2 : 4 DNCB was not observed in any groups. Weak response was observed in 4% of controls, 18.7% of chronic otitis media patients and 5.7% of post treatment cases. Serum IgG, IgA and IgM levels were elevated in chronic otitis media patients from controls but once the infections were eliminated by treatment their values became insignificant (p 0.05) from controls. Presence of Malnutrition significantly contributed to suppression of CMI response but no suppression of humoral immunity was observed. © 1994 Association of Otolaryngologists of India.
Clinical and experimental studies in otomycosis
(1980) M.J. Joy; M.K. Agarwal; H.C. Samant
[No abstract available]
Epithelial isoantigens A, B and H in oral carcinomas
(1985) Y.N. Gupta; S. Gupta; I.J. Singh; N.N. Khanna; M.K. Agarwal
Epithelial tissue isoantigens A,B and H were studied in 182 patients with oral lesions. These patients included 24 patients with premalignant leukoplakic dysplasias and 158 with oral squamous cell carcinomas of various sites in the oral cavity. Loss of isoantigen was seen in 33.33% of patients with leukoplakias and 36.23% of those with carcinomas. The test was found to be negative in all patients showing regional lymph node or distant metastases. The present study indicates that the test can be usefully employed in the evoluation of oral malignancy, its early immunologic diagnosis and as a guide to prognosis in followup studies.
Extramedullary plasmacytoma of the larynx
(1979) M.K. Agarwal; O.P. Gupta; H.C. Samant; S. Khanna
A rare case of plasmacytoma of the larynx is described and the literature relating to plasma cell lesions in the larynx is briefly reviewed. Salient features helping in the diagnosis and management of plasmacytoma are highlighted.
Fibrosarcoma of nose and paranasal sinuses
(1980) M.K. Agarwal; S. Gupta; O.P. Gupta; H.C. Samant
Involvement of nose and maxilla by fibrosarcoma is extremely rare. Only a few cases of fibrosarcoma arising in this region are reported in the world literature. Two cases of fibrosarcoma are described, and the literature relating to this disease entity is briefly reviewed. Salient features helping in the diagnosis and management of fibrosarcoma also are highlighted. Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company
Fibrous dysplasia of the mastoid
(1980) H.C. Samant; M.K. Agarwal; O.P. Gupta; S. Khanna
Involvement of the mastoid by osteogenic tumors occurs on rare occasions. The commonest among them is an osteoma. About 48 cases of osteoma of the mastoid region have been reported so far in the literature. Because of the rarity of this type of lesion, the following case is reported.
Hemangioendothelioma of the neck
(1979) M.K. Agarwal; O.P. Gupta; H.C. Samant; S. Khanna
A rare case of hemangioendothelioma of the neck is described. Salient features helping in the diagnosis and management of this type of lesion are also highlighted.
Hydatid disease of the head and neck
(1978) H.C. Samant; M.K. Agarwal; O.P. Gupta; S. Gupta
Two cases of hydatid cyst are reported, one in the right parotid region involving the deep lobe and the other in the superficial subcutaneous tissue of the sub-mental region. Cystic swellings, where no definite preoperative diagnosis can be arrived at, call for a high suspicion rate for hydatid disease and, even in the nonendemic areas, Casoni's test and complement fixation tests should be carried out. © 1978 Association of Otolaryngologists of India.
Immunological evaluation of children undergoing tonsillectomy
(1979) D. Gogol; O.P. Gupta; M.K. Agarwal; R.M. Gupta
This study was carried out on 80 patients undergoing tonsillectomy for chronic tonsillitis. Twenty healthy school children in the same age group were investigated for control values. Ten children were also available for evaluation of any immunological change after tonsillectomy. No significant variation was seen in the serum IgG, IgA, and IgM levels before and after tonsillectomy. Peripheral absolute lymphocyte count was higher in the pre-operative cases as compared to the control group, and this count became near normal following tonsillectomy. Skin tests with recall antigens PPD and Candida and contact sensitizing agent 2:4 DNCB showed an improved cell mediated immune response following tonsillectomy.
Multiple myeloma invading the larynx
(1981) M.K. Agarwal; H.C. Samant; O.P. Gupta; S. Khanna
A rare case of invasion of the larynx by multiple myeloma is described, and the literature relating to plasma-cell lesions in the larynx is briefly reviewed. Salient features helping in the diagnosis and management of this disease are also discussed.
Mycological and bacteriological studies in otomycosis
(1980) M.J. Joy; M.K. Agarwal; H.C. Samant; O.P. Gupta; B.M. Sharma
The present study was carried out on 185 patients. Aspergilli or Candida were isolated in 93.5% of cases. A.niger was found to be the most common fungus causing otomycosis (44.3 %). Mixed infection with more than one fungus was infrequent. Proteus species, staphylococcus aureus and E.coli were the commonest pathogenic bacteria isolated from 60.8% cases of otomycosis associated with discharge from the ears. An experimental study was also made for the production of otomycosis in 20 human volunteers. Better results were obtained when debris was used to inoculate the healthy ear. In 6 cases (30.7%), the healthy ear could be infected successfully. © 1980 Association of Otolaryngologists of India.
Mycosis fungoides of the larynx
(1982) M.K. Agarwal; S. Gupta; O.P. Gupta
A rare case of mycosis fungoides involving almost the right half of the larynx in a 55-year-old male is being reported perhaps for the first time in the literature. Clinically the case appeared to be laryngeal cancer and diagnosis was established only by histopathological examination. Histologically, the presence of 'Pautrier's microabscesses' is pathognomonic of this disease.
Nasal glioma
(1979) M.K. Agarwal; H.C. Samant; O.P. Gupta; S. Gupta
A case of an extranasal glioma is reported. A brief discussion as to the etiology, clinical manifestations and management of the lesion is made. © 1979 Association of Otolaryngologists of India.
Nasal, pharyngeal, and laryngeal manifestations of hypothyroidism
(1977) O.P. Gupta; P.L. Bhatia; M.K. Agarwal
A plea is made for a high degree of suspicion of hypothyroidism in patients with nasal stuffiness, recurrent common colds, discomfort or feeling of a lump in the throat, and change in the voice, especially when examination of nose, pharynx, and larynx reveals no abnormality or only a mild change.
Neurilemmoma of the maxillary sinus
(1980) M.K. Agarwal; O.P. Gupta; H.C. Samant; S. Gupta
[No abstract available]
Neurofibroma of the maxillary antrum
(1979) M.K. Agarwal; O.P. Gupta; H.C. Samant; Saroj Gupta
Neurofibromas in the maxillary antrum are very rare. A review of the literature disclosed only one case occurring at this site. The present report adds one more interesting case to the world literature. © 1979.