Browsing by Author "M.L. Sharma"

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Actions of some flavonoids on specific and non-specific immune mechanisms
(Urban und Fischer Verlag Jena, 1996) M.L. Sharma; B. Singh; B.K. Chandan; A. Khajuria; A. Kaul; S. Bani; S.K. Banerjee; S.S. Gambhir
The immunomodulatory activity of some flavonoids on antigen specific humoral and cell mediated immune responses and complement-mediated hemolysis has been investigated and compared with that of levamisole. Flavanone, 6-methoxyflavanone, 7-methoxyflavanone and bavachinin enhanced the sheep erythrocyte (SRBC), induced primary and secondary humoral immune responses in mice, and 6-hydroxyflavanone, 7-hydroxyflavanone and rutin inhibited primary response. Levamisole slighty stimulated the primary and suppressed the secondary response. All the flavonoids tested decreased the manifestation of SRBC induced delayed type hypersensitivity reaction and showed no effect on classical or alternative pathway dependent hemolysis. The studies revealed the significant immunomodulatory potential of these flavonoids, methoxy derivatives having immunostimulatory activity and hydroxy derivatives immunosuppressive properties.
Estimation of the source parameters of the Nepal earthquake from strong motion data
(Springer Netherlands, 2016) A. Joshi; Monu Tomer; Sohan Lal; Sumer Chopra; Sandeep Singh; Sanjay Prajapati; M.L. Sharma; Sandeep
Kathmandu and its surrounding region were rocked recently by a devastating earthquake on April 25, 2015. This is the largest earthquake that has occurred in this region since the past eight decades. This earthquake was recorded on strong motion stations located about 470–522 km away from its epicenter. Records of accelerographs from these stations have been used to determine the location of this earthquake using hypo71 algorithm given by Lee and Lehr (HYPO71, a computer program for determining hypocenter, magnitude and first motion pattern of local earthquakes. US Geological Survey Open file report, 100, 1975). The recorded accelerograms have been corrected for site effects using site amplification curve obtained from ambient seismic noise recorded at each station. Site effect has been computed using H/V ratio method given by Nakamura (Q Rep RTRI 30(1):25–33, 1989) using ambient noise data. The corrected record is further used to obtain source displacement spectra. The source spectrum obtained from strong motion data is compared with theoretical source spectrum obtained from Brune’s (J Geophys Res 75:4997–5009, 1970) model for the horizontal components. The long-term flat level and corner frequency from source displacement spectra are used to calculate stress drop, source radius and seismic moment of this earthquake. The present study indicates that the Nepal earthquake originated 12.0 km below the epicenter located at 27.93°N, 84.70°E. The source radius, stress drop and seismic moment of this earthquake estimated from source displacement spectra are 44.13 ± 3.85 km, 18.68 ± 5.93 bars and 3.53 ± 0.28 × 1027 dyne cm, respectively. © 2016, Springer Science+Business Media Dordrecht.
Modeling of the strong ground motion of 25th April 2015 Nepal earthquake using modified semi-empirical technique
(Springer International Publishing, 2018) Sohan Lal; A. Joshi; Sandeep; Monu Tomer; Parveen Kumar; Chun-Hsiang Kuo; Che-Min Lin; Kuo-Liang Wen; M.L. Sharma
On 25th April, 2015 a hazardous earthquake of moment magnitude 7.9 occurred in Nepal. Accelerographs were used to record the Nepal earthquake which is installed in the Kumaon region in the Himalayan state of Uttrakhand. The distance of the recorded stations in the Kumaon region from the epicenter of the earthquake is about 420–515 km. Modified semi-empirical technique of modeling finite faults has been used in this paper to simulate strong earthquake at these stations. Source parameters of the Nepal aftershock have been also calculated using the Brune model in the present study which are used in the modeling of the Nepal main shock. The obtained value of the seismic moment and stress drop is 8.26 × 1025 dyn cm and 10.48 bar, respectively, for the aftershock from the Brune model.The simulated earthquake time series were compared with the observed records of the earthquake. The comparison of full waveform and its response spectra has been made to finalize the rupture parameters and its location. The rupture of the earthquake was propagated in the NE–SW direction from the hypocenter with the rupture velocity 3.0 km/s from a distance of 80 km from Kathmandu in NW direction at a depth of 12 km as per compared results. © 2018, Institute of Geophysics, Polish Academy of Sciences & Polish Academy of Sciences.
Training participation of women sarpanchs towards rural development in bialspur district of chhattisgarh
(Plant Archives, 2020) Kumari Jyoti; M.L. Sharma
The given study was conducted in Bilaspur district of Chhattisgarh state of India during the session 2015-16 to determine the training pattern and participation of tribal and non- tribal women sarpanhcs (Village Head). Statistical data received form Zila panchayat office indicated 645 Gram Panchayat, out of which 336 Gram Panchayat were headed by women sarpanchs. Out of those 336 women leading panchayat, one-third viz. 112 panchayat were selected randomly for the study. Further the 112 respondents (women leaders) were divided into two groups i.e. Tribal (56 women leaders) and Non- tribal (56 women leaders) respondents of the given districts. Data were analyzed with suitable statistical tools. The research study indicated that, training need of the respondents were mostly in village development activities and agriculture with 21.43 per cent and 17.85 per cent respectively. Village development activities were given first rank by both the categories of respondents as it was most preferably among those lists of training. Cent per cent respondents participated in training activities. © 2020 Plant Archives. All rights reserved.