Browsing by Author "Manish Sharma"

Now showing 1 - 9 of 9

A Multiple Millimeter-Wave 5G MIMO Antenna Including n257/n258/n259/n260/n261 FR2-Bands with High Diversity Performance
(Institute of Electrical and Electronics Engineers Inc., 2023) Manish Sharma; Kanhaiya Sharma; Smrity Dwivedi; Dinesh Kumar Singh; Rana Gill; Naresh Kumar
This communication focuses on a two-port MIMOWB configuration wide-bandwidth antenna for future 5G high-speed wireless applications radiating electromagnetic energy. The single-port antenna offers impedance bandwidth of 24.50GHz-41.675GHz for HFSS EM-simulator and 23.63GHz-43.13GHz for CST-Microwave Studio EM-simulator. The square-radiating patch radiating EM-wave with the rectangular slot on top-surface & beveled-ground on the bottom surface of dielectric with permittivity 2.20 and thickness 0.787. Also, the compact dimension of the antenna is 12.0 × 15.0 mm2 and the two-port transformed dimensions are 24.0 × 15.0 mm2. The SFD studying surface-current-distribution (SCD) with directional 2-D radiation patterns in n257, n258, n259, n260, and n261 5G-millimeter wave bands infrastructure. The MIMO antenna also offers averaged peak gain of 4.50dBi with high diversity ECC and DG parameters. © 2023 IEEE.
A rapid and sensitive colorimetric discrimination and detection of cysteine, homocysteine and glutathione by phloroglucinol-functionalized silver nanoresonators with real applications
(Royal Society of Chemistry, 2023) Anurag Kumar Singh; Raksha Singh; Minu Yadav; Manish Sharma; Ida Tiwari; K.K. Upadhyay
This study describes the preparation and application of simple yet effective silver nanoprobes for the facile colorimetric discrimination and detection of cysteine, homocysteine and glutathione in real time at the micro molar levels with three distinct colors. These nanoprobes were further exploited to detect and determine cysteine and glutathione from their respective commercial samples, with recoveries exceeding 80%. FT-IR spectroscopy, UV-Vis spectroscopy, SEM, TEM, EDAX, AFM and DLS studies have supported our findings. © 2023 The Royal Society of Chemistry.
Colorimetric and SERS detection of H2S by D (±) galactose functionalized truncated hexagonal bipyramidal silver nanoresonators
(Elsevier B.V., 2023) Minu Yadav; Raksha Singh; Anurag Kumar Singh; Manish Sharma; Ida Tiwari; Kaushal Kumar Upadhyay
We report hereby, a simple and easy to perform experimental protocol for highly selective and real time dual mode (Colorimetric and SERS) detection of hydrogen sulfide (H2S) in aqueous medium through galactose activated silver nanoresonators. The truncated hexagonal bipyramids were clearly seen in TEM images of as prepared silver nanoparticles. The interaction of H2S with these AgNPs induced their etching followed by agglomeration and led optical (greenish yellow to brown) as well as SERS changes. The optical changes were further exploited to determine the H2S from its two spiked samples of human saliva and blood serum each with their percent recovery rates of 91, 82 and 67, 72 respectively. These determinations were totally free from any visual interference from any biothiols like cysteine, homocysteine and glutathione. The optimized silver nanosensor exhibited an excellent linear response in the concentration range of 50–130 nM along with its limit of detection (LOD) as 2.83 nM. Moreover, consecutive additions of different aliquots of H2S to a fixed volume of these silver colloids exhibited stepwise decrease in intensity of their absorption bands in the Raman silent (10–500 cm−1) and Raman finger print regions (500–1800 cm−1) upon their excitation at 532 nm. Our findings are well supported by spectroscopic (FTIR, UV–Vis and Raman) and microscopic (SEM, TEM, DLS and zeta potential). © 2023 Elsevier B.V.
Glucosamine functionalized gold nanoparticles for the specific detection and colorimetric assay of glutathione in real samples
(Royal Society of Chemistry, 2024) Anurag Kumar Singh; Saumya Singh; Raksha Singh; Manish Sharma; Ida Tiwari; K.K. Upadhyay
In this study, we report an experimental protocol based on gold nanoparticles (GNPs) for the selective and efficient chromogenic detection and determination of glutathione in two pharmaceutical samples, viz. Maxiliv and Glutaderm, in real time. The glucosamine hydrochloride driven hydrothermal (40 °C) wet chemical reduction of gold(iii) chloride trihydrate resulted in gold sol with a ruby red color exhibiting a surface plasmon resonance (SPR) at 521 nm. The most frequent average size of these GNPs was found to be 23 nm and their concentration was evaluated to be 8.4 nM. The zeta potential measurements and interaction of these GNPs against NaCl of varying molarities indicated their long-term stability. According to SEM analysis, these GNPs exhibited a nanowire morphology and produced a categorical color change from ruby red to blue selectively with GSH in the presence of a wide range of similar analytes in real time. UV-vis, FT-IR, XPS, SEM, TEM, AFM, EDAX, DLS, zeta potential, and other techniques were used to characterize the as-synthesized GNPs and to study their interaction with glutathione. © 2024 The Royal Society of Chemistry.
Naked-eye detection of cysteine/homocysteine through silver nano-resonators and specific identification of homocysteine through nanoresonator-thiosulphate conjugate
(Royal Society of Chemistry, 2022) Raksha Singh; Anurag Kumar Singh; Minu Yadav; Manish Sharma; Ida Tiwari; K.K. Upadhyay
This study presents simultaneous colorimetric detection of two very similar amino thiols viz. cysteine and homocysteine at their micro and sub-micromolar levels, respectively, through the aggregation of citrate capped silver nanoparticles. A rare kind of categorical naked-eye detection of homocysteine over cysteine was accomplished through the conjugation of these AgNPs with thiosulphate. The UV-Vis and SERS characteristics of these AgNPs were also more prominent with homocysteine compared to cysteine. The quantification of cysteine was performed in a pharmaceutic sample with an accuracy of 89 ± 5%. © 2022 The Royal Society of Chemistry.
Quinoa and sea buckthorn underutilized crops with diverse potential
(CRC Press, 2025) Geetanjali Sageena; Khushboo Sharma; Manish Sharma
[No abstract available]
Regional air quality: biomass burning impacts of SO2 emissions on air quality in the Himalayan region of Uttarakhand, India
(Springer Science and Business Media B.V., 2024) Alok Sagar Gautam; Sanjeev Kumar; Sneha Gautam; Karan Singh; Kripa Ram; Devendraa Siingh; Balram Ambade; Manish Sharma
In the present study, continuous ground-based SO2 monitoring has been planned over the Srinagar Garhwal Valley of Uttarakhand. The monsoon (M-2018), post-monsoon (PoM-2018), winter (W-2019), pre-monsoon (PrM-2019), and M-2019 have high SO2 concentrations (3.66 ± 2.05 μg/m3, 5.54 ± 2.23 μg/m3, 6.42 ± 1.79 μg/m3, 7.56 ± 3.53 μg/m3 6.45 ± 3.49 μg/m3) at 1900, 2000, 1800, 1900, and 1900 local time attributed mainly due to biomass burning and long-range transportation of pollutants. A drastic change in the SO2 concentration was observed from 4.81 to 17.39 μg/m3 in May 2019 with a strong correlation of 0.61 with fire counts during an extensive forest fire. Due to the wet scavenging process, Jul 2018 (1.07 ± 0.82 μg/m3) showed the lowest SO2 concentration. Temperature, humidity, and wind speed significantly correlate with SO2 in different seasons. Overall, the air quality in the SGV region is good, but it worsens during forest fires, although it still remains within satisfactory levels. HYSPLIT model trajectories, cluster, and CWT analysis indicate the transportation of air mass from the Gulf region, Sahara Desert, Pakistan, and Afghanistan to Srinagar with a significant contribution of 40.43 to 72.29% air mass and have highest contribution more than 7 μg/m3. We have also observed weekend effects (reduction in the pollutant concentration) in Jul 2018, Sep 2018, Feb 2019, Apr 2019, and May 2019. Overall, this study highlights the seasonal variations in SO2 concentrations, the impact of forest fires on air quality, the influence of meteorological factors, the long-range transport of pollutants, and the presence of weekend effects in the SGV region of Uttarakhand. © 2023, The Author(s), under exclusive licence to Springer Nature B.V.
Sunlight-powered total green synthesis of silver nanoresonators from aqueous extract of soybean (Glycine max) chunks: A highly specific colorimetric probe for H2S
(Elsevier B.V., 2024) Raksha Singh; Minu Yadav; Manish Sharma; Ida Tiwari; K.K. Upadhyay
We report herein a total green synthesis of silver nano resonators having 43.77 nM concentration with their most frequent average size of ∼ 17 nm. The reaction mixture comprising of aqueous extract of soybean (Glycine max) chunks (15 mL) and AgNO3 (1 mL, 0.1 M) in a 100 mL round bottom flask was irradiated with sunlight for 3 hrs to bring out this synthesis. The as prepared AgNPs were fully characterized through various spectroscopic (FTIR & UV–Vis) and microscopic (SEM, TEM, SAED, EDX, AFM and DLS) studies. The same AgNPs were further exploited for highly selective detection and determination of a janus faced analyte like H2S from its aqueous solution at submicromolar level (LOD 7.39×10-7 M). The H2S is known for its role as one of the gaso-neurotransmitters in humans beside playing dubious role towards our environment. Two spiked real samples of water from pond and sewage were subjected for determination of their H2S content against these AgNPs, showed recoveries of 99 % and 106 % respectively. © 2023 Elsevier B.V.
Synthesis and in vitro antiplasmodial activities of fluoroquinolone analogs
(2012) Sandeep K. Dixit; Nidhi Mishra; Manish Sharma; Shailja Singh; Alka Agarwal; Satish K. Awasthi; V.K. Bhasin
Fluoroquinolone analogs were synthesized by simple alkylation followed by click chemistry and evaluated for their antimalarial in vitro against chloroquine sensitive strain of Plasmodium falciparum while ciprofloxacin was used as standard. Our results showed that the compound 12 was found most active with IC 50 value of 1.33 μg/mL while ciprofloxacin showed IC 50 = 8.81 μg/mL. Therefore, screening of either known or unknown quinolone/fluoroquinolone analogs are worthwhile to find more potent antimalarial drugs which might prove useful in the treatment of mild or severe malaria in human either alone or in combination with existing antimalarial drugs. © 2012 Elsevier Masson SAS. All rights reserved.