Browsing by Author "Narendra R. Chaubey"

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Direct C-H Arylation of N-Heterocycles with Aryl Triazenes Using Molecular Oxygen as Oxidant
(Wiley-Blackwell, 2019) Narendra R. Chaubey; Ramesh Kumar Vishwakarma; Krishna Nand Singh
An efficient C−H arylation of N-heterocycles has been developed using stable and easily accessible aryl triazenes in the presence of oxygen under metal- and peroxide-free conditions. The methodology is regiospecific and applicable to a wide range of electron-deficient N-heterocycles and aryl triazenes as demonstrated by 20 examples with yields ranging from 32–83%. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Metal-free decarboxylative acylation of isoquinolines using α-keto acids in water
(Elsevier Ltd, 2017) Narendra R. Chaubey; Krishna Nand Singh
An efficient method for acylation of isoquinolines has been developed using α-ketoacids under metal- and additive-free conditions in water. The protocol involves C(sp2)–H functionalization of isoquinolines providing an easy access to C1-benzoylated isoquinolines, which constitute the core structure of a number of biological active compounds and serve as key intermediate in the synthesis of many alkaloids. © 2017 Elsevier Ltd
Visible light-promoted self-coupling of N-chloramines at room temperature: A metal-free access to substituted amides
(Taylor and Francis Inc., 2019) Narendra R. Chaubey
An efficient protocol to synthesize substituted amides via self-coupling of N-chlorobenzylamines has been developed under visible light-promoted mild condition. Both the electron-deficient and electron-rich benzylamines undergo self-coupling very readily to produce the amide linkage under given reaction conditions. © 2019, © 2019 Taylor & Francis Group, LLC.