Browsing by Author "Narsingh Verma"

Now showing 1 - 3 of 3

Effects of Indo-Mediterranean style diet and low fat diet on incidence of diabetes in acute coronary syndromes
(Nova Science Publishers, Inc., 2017) R.B. Singh; Banshi Saboo; Anuj Mahashwari; Kshitij Bharatdwaj; Narsingh Verma; Krasimira Hristova; S. Ghosh; M.A. Niaz; Jaipaul Singh; Ernest A. Adeghate; K.A. Bidasee; Mukta Singh; Anubha Mishra; Surbhi Tripathi; Diksha Singh; Smita Pandey; Swarnika Srivastava; Poonam Jaglan
Introduction: Obesity and diabetes are known to increase the risk of mortality due to acute coronary syndromes (ACSs). Effect of ACSs on risk of diabetes is unknown. This study examined the effect of the Mediterranean-style diet compared to a low-fat diet on incidence of obesity, diabetes and prediabetes in patients with ACSs. Subjects and Methods: A randomized, single-blind, controlled trial was carried out on 406 patients with ACSs diagnosed by WHO criteria. The intervention group received a low-energy Indo-Mediterranean diet and the control group received a fat-modified diet, according to the NCEP Step 1 diet. The main outcome measures were compliance with diets and weight loss at one year and frequency of obesity and diabetes and all-cause mortality after two years. Results: The intervention group received significantly greater amounts of Mediterranean-style foods and lower amounts of Western foods compared to the control group at one year of follow-up. The frequency of obesity and known diabetes, as well as prediabetes, was comparable in the two groups at the inception of the study. However, after 2 years, the incidence of obesity, known diabetes, as well as prediabetes (n = 55, 26.9%. vs. 11, 5.4%, P < 0.001) was significantly lower in the intervention group, compared to the reference. In contrast, the incidence of prediabetes was significantly increased in the control group compared to reference (n = 50, 20.2, vs. 58, 28.7%, P < 0.01). The incidence of prediabetes after 2 years was significantly higher in the control group compared to the intervention group (28.7% vs. 5.4%, P < 0.001). These findings were associated with a significantly greater adherence score for the Indo-Mediterranean diet in the intervention group compared to that for the diet of the control group. A greater weight loss of >0.5 kg was associated with significantly (p < 0.001) fewer cardiovascular events and less mortality, more so in the intervention group than in the control group. The total mortality was 14.7% in the intervention group and 25.2% in the control group (p < 0.01) after two years. Conclusions: The Indo-Mediterranean-style diet is effective in decreasing the incidence of known diabetes and prediabetes. However, in the control group, there is no decline in known diabetes but a significant increase in the incidence of prediabetes, compared to the reference indicating that ACSs may have predisposed subjects to prediabetes without any beneficial effect of the low-fat control diet. © 2017 Nova Science Publishers, Inc.
Evidence-based recommendations for insulin intensification strategies after basal insulin in type 2 diabetes
(Elsevier Ltd, 2017) Sujoy Ghosh; A.G. Unnikrishnan; Banshi Saboo; Jothydev Kesavadev; S.R. Aravind; Sarita Bajaj; Rajesh Rajput; Krishna Seshadri; Narsingh Verma; Arvind Gupta; Brij Mohan Makkar; Mihir Saikia; Shailaja Kale; Suresh Damodaran; Ashish Dengra; T.K.M. Eashwar; Anuj Maheshwari; Sharad Pendsey; Sanjeev R. Phatak; Surendra Kumar Sharma; Surya Kumar Singh; A. Ramachandran; Abdul H. Zargar; Shashank R. Joshi; Shaukat M. Sadikot
Over the time due to progressive nature of diabetes, proactive intensification of the existing insulin therapy becomes imminent as it minimizes patients’ exposure to chronic hypo/hyperglycaemia and reduces weight gain while achieving individualized glycaemic targets. This review focuses on the strength of evidence behind various options for intensification, primarily the insulins as also the GLP-1 analogues. The recommendations presented here are meant to serve as a guide for the physician managing type 2 diabetes patients requiring insulin intensification upon failing of basal insulin therapy. © 2017 Diabetes India
The Twelve Fundamental Dimensions of a High Quality Indo-Mediterranean Diet
(Faculty of Medicine, University of Banja Luka, 2023) Ram B. Singh; Adrian Isaza; Ghizal Fatima; Anuj Maheshwari; Narsingh Verma; Shashank Joshi; Richa Mishra; Poonam Tiwari; Shilpa Joshi; Sudha R. Yeluri; Aminat Magamedova; Magomed Magamedov
High-quality Indo-Mediterranean foods are characterised with unrefined, unprocessed foods, whole grains such as dry millets and beans and porridge. Vegetables such as leaves and gourds, nuts and fruits such as apples, grapes, papaya, guava, etc are major components of this diet. It seems that healthy vegetable oils such as olive, mustard, rape seed oil and protein sources that are beneficial; beans, pulses, cottage cheese are crucial in this diet. Among animal sources, white meats; such as sea foods should also be part of this diet. Vegetables and spices with medicinal properties; gourds, turmeric, fenugreek, coriander and cumin may also be called high quality nutraceutical foods, respectively. There is a need to find out traditional foods from all other countries which may be protective and healthy. There is evidence that calories have tremendous role in weight gain and weight loss. It seems that emphasis on food quality is crucial for prevention of oxidative stress and inflammation in the adipocytes, which predispose obesity and risk of cardiovascular diseases (CVDs) and diabetes. There are gaps in knowledge about the qualities of traditional foods, which prompt authors to present this communication. © 2023 Singh et al.