Browsing by Author "Neha Shukla"

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Comparative evaluation of pit & fissure sealant retention using cotton roll & rubber dam isolation techniques – a systematic review & meta-analysis
(Springer Nature, 2025) Neha Shukla; Zainab Akram; Pg G.Naveen Kumar; Mahesh R. Khairnar; Jadhav Sachin Kumar; Savitha S. Priyadarsini
Background: Isolation with cotton rolls does not always provide as complete isolation as rubber dam, especially in procedures where absolute moisture control is critical. Therefore, this review aims to summarize and analyze previous studies evaluating the retention and marginal integrity of pit & fissure sealant using rubber dam and cotton roll isolation techniques during dental treatment in children. Material and methods: In accordance with PRISMA guidelines, search yielded 1361 articles, with seven RCTs and one non-RCT design meeting the inclusion criteria. Data were extracted on study design, sample size, sealant type, follow-up duration, retention rates, and caries incidence. Results: The comparison of retention rate between rubber dam and cotton roll at six months difference was non-significant (OR:1.15; p = 0.64) while there was significant difference at 12 month (OR:2.23; p < 0.001). The difference for the marginal integrity was statistically significant at six months (OR:2.00; p = 0.03) while non-significant difference observed (OR:1.74; p = 0.10) at 12 months. Conclusion: The sealant placed using a rubber dam as an isolation technique showed higher retention than the cotton roll after 12 months. In terms of marginal integrity, the performance of the rubber dam and cotton roll was equivalent at the end of 12 months. © The Author(s), under exclusive licence to British Dental Association 2024.
Comparative evaluation of pit & fissure sealant retention using cotton roll & rubber dam isolation techniques – a systematic review & meta-analysis
(Springer Nature, 2024) Neha Shukla; Zainab Akram; P. G. Naveen Kumar; Mahesh R. Khairnar; Sachin Kumar Jadhav; Savitha Priyadarsini
Background: Isolation with cotton rolls does not always provide as complete isolation as rubber dam, especially in procedures where absolute moisture control is critical. Therefore, this review aims to summarize and analyze previous studies evaluating the retention and marginal integrity of pit & fissure sealant using rubber dam and cotton roll isolation techniques during dental treatment in children. Material and methods: In accordance with PRISMA guidelines, search yielded 1361 articles, with seven RCTs and one non-RCT design meeting the inclusion criteria. Data were extracted on study design, sample size, sealant type, follow-up duration, retention rates, and caries incidence. Results: The comparison of retention rate between rubber dam and cotton roll at six months difference was non-significant (OR:1.15; p = 0.64) while there was significant difference at 12 month (OR:2.23; p < 0.001). The difference for the marginal integrity was statistically significant at six months (OR:2.00; p = 0.03) while non-significant difference observed (OR:1.74; p = 0.10) at 12 months. Conclusion: The sealant placed using a rubber dam as an isolation technique showed higher retention than the cotton roll after 12 months. In terms of marginal integrity, the performance of the rubber dam and cotton roll was equivalent at the end of 12 months. © The Author(s), under exclusive licence to British Dental Association 2024.
COMPARATIVE EVALUATION OF RETENTION AND CARIES PREVENTIVE EFFECT OF HYDROPHILIC AND HYDROPHOBIC PIT AND FISSURE SEALANTS: A SYSTEMATIC REVIEW AND META ANALYSIS
(Elsevier Inc., 2025) Jadhav Sachin Kumar; Zainab Akram; Pg G.Naveen Kumar; Mahesh R. Khairnar; Neha Shukla
Background: Dental sealants are critical in preventing caries by protecting pits and fissures from food and microorganism accumulation. Sealants are categorized as hydrophobic and hydrophilic. Hydrophobic sealants exhibit higher retention but less effective in moist environments, hydrophilic sealants perform better under such conditions. Evaluating retention and caries prevention efficacy of these sealants is essential for optimizing dental care practices. This review evaluates retention and caries preventive efficacy of both sealants. Materials and Methods: Data on study design, sample size, sealant type, follow-up duration, retention rates, and secondary caries incidence were extracted. The risk of bias assessed using RevMan 5.4, and meta-analyses were conducted with both random-effects model and fixed-effects model based on heterogeneity and nature of included studies. Results: Adhering to PRISMA guidelines, 15 Randomized Controlled Trials (RCTs) and 3 Non-Randomized Controlled Trials (NRCTs) met with inclusion criteria. Hydrophilic sealants showed significantly higher retention rates at 3 months (OR: 3.00, 95 % CI: 1.46-6.16) and 12 months (OR: 2.00, 95 % CI: 1.35-2.96). However, no significant differences observed at 6, 9, and 18 months. Caries prevention efficacy was similar for both sealant types across all follow-up periods, with low heterogeneity indicating consistent results. Discussion: Hydrophilic sealants initially provide better retention due to moisture-resistant properties but do not sustain this advantage in long run. Both sealant types are equally effective in preventing caries. These findings align with prior studies, emphasizing importance of moisture control in sealant application. Conclusion: Hydrophilic sealants exhibit superior short-term retention and similar caries prevention efficacy compared to hydrophobic sealants. © 2024 Elsevier Inc.
Salivary alpha amylase as a diagnostic biomarker for dental caries – A systematic review and meta analysis
(Elsevier Ltd, 2025) S. Savitha Priyadarsini; Puvvadi G. Naveen Kumar; Mahesh R. Khairnar; Zainab Akram; Ridhi Ghodela; Jadhav Sachin Kumar; Neha Shukla
Objective: This systematic review and meta-analysis aimed to assess the association between the dental caries and the level of salivary alpha amylase activity among caries active and caries free individuals. Design: This review followed the PRISMA guidelines and registered in PROSPERO (CRD42024518973). A comprehensive search across various research databases until January 31, 2024 yielded 1031 articles, where multiple screening ultimately narrowed it to 13 articles. Appropriate cross sectional studies comparing caries active (CA), caries free (CF) group and evaluating their level of salivary alpha amylase activity were included. Results: The meta-analysis was performed on all 13 included studies utilizing a random effects model and two sub group analysis were performed where studies with salivary alpha amylase activity estimated using spectrophotometer and autoanalyzer were analyzed separately among caries active and caries free group. The pooled data reveals that the salivary alpha amylase activity was significantly higher (p = 0.005) in caries active group compared to caries free group with a standardized mean difference of 1.30. Conclusion: This review indicated the differences in the salivary alpha amylase activity among caries active and caries free individuals which could aid in identifying individuals susceptible to dental caries thereby offering new insights for preventive dentistry by assessing their caries risk, enabling tailored preventive strategies. © 2024 Elsevier Ltd
The Impact of Graphic Health Warning Labels on Smokeless Tobacco Packets on Motivation to Quit among Current Users: A Cross-Sectional Study
(Kerman University of Medical Sciences, 2025) Jadhav Sachin Kumar; Puvvadi Gopalakrishna Naveenkumar; Mahesh R. Khairnar; Zainab Akram; Neha Chauhan; Neha Shukla
Background: Smokeless tobacco (SLT) use constitutes a considerable public health concern, especially in India, where there are more than 300 million users. This study seeks to assess the influence of graphic health warning labels (GHWLs) on smokeless tobacco (SLT) packaging on encouraging cessation among users. Methods: A cross-sectional study was conducted at the Faculty of Dental Sciences, BHU, Varanasi outpatient department, from December 2023 to April 2024. The study involved 387 participants, selected via simple random sampling, who were current smokeless tobacco users. Data was collected through structured interviews using a validated questionnaire. Statistical analysis was performed using SPSS version 21.0, with a significance level set at P < 0.05. Findings: Awareness of GHWLs was high, with 91.7% of participants recognizing the labels. Among these, 66% considered quitting or reducing smokeless tobacco use due to the labels. Increased health awareness and serious consideration to quit were reported by 50.1% of participants, while 28.9% reported no impact. Awareness of tobacco cessation clinics was moderate at 48.1%, and 66.1% expressed willingness to seek help, primarily due to health concerns. Positive correlations were found between education level and awareness (r = 0.387) and education and attitude towards quitting (r = 0.227). Younger participants and those with shorter durations of smokeless tobacco use exhibited higher health awareness and a greater likelihood of considering cessation. Conclusion: GHWLs are a potent tool in tobacco control, significantly influencing smokeless tobacco users’ intentions to quit. A multifaceted approach involving GHWLs and comprehensive support systems can substantially reduce smokeless tobacco use and its associated health risks. © 2025 The Author(s); Published by Kerman University of Medical Sciences.