Browsing by Author "Om Prakash Verma"

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A Narrative Review on Dialectical Behavior Therapy for Patients with Depressive Difficulties
(Bentham Science Publishers, 2022) Aryendu Kumar Saini; Pranay Wal; Ankita Wal; Rashmi Saxena Pal; Om Prakash Verma
Background: Dialectical behavior therapy (DBT) is a type of cognitive behavioral therapy (CBT) that was earlier intended to treat only patients with borderline personality disorder (BPD), but researchers have found DBT to treat several psychological disorders, including depression. Aim: The article aims to review the clinical shreds of evidence regarding the use of DBT to treat depression. Methods: PubMed literature search was done by applying the year filter range, 2010 to 2021. Another filter applied was “Randomized controlled trial”, so that the strength of evidence could be enhanced. The keywords used were “Dialectical Behavior Therapy” AND “Depression”. Results: 33 articles were found, out of which only 20 relevant articles were reviewed. DBT was found to alleviate depressive symptoms associated with different psychological disorders like bipolar disorder and BPD but the number of studies that validated the aforementioned were less than those studies which showed that DBT had no significant effect on the patients with depressive difficulties. The long-term effect of DBT for treating depression is under suspect, as studies showed that DBT got ineffective during the follow-ups. Conclusion: DBT shows benefits in depression, but further studies are still required to validate this concretely as DBT did not show a significant effect when compared to its control counterparts. There is much need for future studies which can evaluate the long-term efficacy of DBT in depression, which is another challenging area because follow-up data did not favor DBT. © 2022 Bentham Science Publishers.
Identification of QTLs for zinc deficiency tolerance in a recombinant inbred population of rice (Oryza sativa L.)
(John Wiley and Sons Ltd, 2022) Bapsila Loitongbam; Pawan Kumar Singh; Rameswar Prasad Sah; Om Prakash Verma; Balwant Singh; Prashant Bisen; Sandhya Kulhari; Sanket R Rathi; Sameer Upadhyay; Nagendra Kumar Singh; Rabin Sahu; Rakesh Kumar Singh
BACKGROUND: Deficiency of Zn is a major soil constraint in rice plant growth and yield. Edaphic factors such as Zn deficiency in soil in relation to plant performance are still poorly understood. Here, we report promising quantitative trait loci (QTL) conferring tolerance to Zn deficiency, which were identified through biparental mapping. The experiment was conducted using the 236 F7 recombinant inbred line mapping population derived from the cross of Kinandang Patong (Zn deficiency sensitive) and A69-1 (Zn deficiency tolerant). RESULTS: A total of six QTLs (qLB-2B, qLB-4B, qPM-4B, qPM-6B, qRZC-4B, qSZC-4B) on chromosomes 2, 4 and 6 were identified for environment 1, whereas five QTLs (qLB-2 N, qLB-4 N, qPM-4 N, qRZC-4 N, qSZC-4 N) on chromosomes 2 and 4 were detected for environment 2. Among these, five major (51.30, 48.70, 28.60, 56.00, 52.00 > 10 R2) and one minor (5.40 < 10 R2) QTLs for environment 1 and four major (51.48, 50.20, 53.00, 48.00 > 10 R2) and one minor (4.44 < 10) QTLs for environment 2 for Zn deficiency tolerance with a logarithm of odd threshold value higher than 3 were identified. The QTLs (qLB-4B, qPM-4B, qRZC-4B, qSZC-4B, qLB-4 N, qPM-4 N, qRZC-4 N, qSZC-4 N) for leaf bronzing, plant mortality root zinc concentration and shoot zinc concentration identified on chromosome 4 were found to be the most promising and highly reproducible across the locations that explained phenotypic variation from 48.00% to 56.00% with the same marker interval RM6748–RM303. CONCLUSION: The new QTLs and its linked markers identified in the present study can be utilized for Zn deficiency tolerance in elite cultivars using marker-assisted backcrossing. © 2022 Society of Chemical Industry. © 2022 Society of Chemical Industry.