Browsing by Author "P. Chaturvedi"

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Antioxidant property of Smilex china Linn
(2001) Y.B. Tripathi; A.K. Upadhyay; P. Chaturvedi
Smilex china Linn. (Smilacaceae Syn Liliaceae) has special pharmacognostic feature as its root is multiseriate, with sclerenchymatic pericycle. The alcoholic extract of rhizome of S. china shows significant protection against FeSO4 induced lipid peroxidation in rat liver homogenate, but has no effect on the rate of oxidation of reduced glutathione. This fraction scavenges the superoxide and hydroxyl radicals, but the effect was more towards the removal of superoxide than that of hydroxyl radicals. Thus it could be concluded that rhizome of S. china has strong antioxidant property.
Assessment of endocrine response of Inula racemosa in relation to glucose homeostasis in rats.
(1995) Y.B. Tripathi; P. Chaturvedi
Alcoholic extract of the root of I. racemosa lowers blood glucose and enhances liver glycogen without increasing plasma insulin in rats. There is also no increase in degree of degranulation of the beta cells of pancreas. In similar conditions it does not show any effect on activity of adrenal gland. However, thyroid gland undergoes activation at the later stage (delayed response). It appears that hypoglycemic response of I. racemosa is not due to enhanced secretion/synthesis of insulin; the action may be at the peripheral level by potentiating the insulin sensitivity.
Ecological features and traditional knowledge of roscoea alpina royle a medicinal plant in Himalaya
(National Institute of Science Communication and Information Resources, 2021) A. Dhyani; Y.M. Bahuguna; B.P. Nautiyal; V.K. Yadav; P. Chaturvedi; M.C. Nautiyal
Roscoea alpina Royle (Zingiberaceae) commonly known as Kakoli is a perennial medicinal plant endemic to the Himalayas. It has been used in vitality strengthening Ayurveda groups i.e., Astavarga and Jeevaniyagana and in preparation of Ayurvedic formulations e.g., Chyavanprasha and Divya Pidantak Tail. Considering its medicinal uses, high demand and overexploitation, natural habitats were surveyed in subalpine and alpine regions of Garhwal Himalaya for population estimation and to identify elite germplasm. R. alpina frequency was recorded more than 60% in Tungnath, Dayara, Valley of Flowers and Kedarnath populations. However, plant density and area occupied were low compared to other species of subalpine and alpine site. For threat category assessment, IUCN Red List Categories and Criteria were used and conservation status was assigned, based on site to site and for entire Garhwal region of the Western Himalaya. R. alpina, based on extent of occurrence was categorized as Vulnerable and based on number of mature individuals as Endangered for the Garhwal Himalaya. Further, habitat destruction and degradation were the major threats for population reduction in the wild. Morphological variation revealed plants from Tungnath and Kedarnath may be used for future propagation and domestication programs. © 2021, National Institute of Science Communication and Information Resources. All rights reserved.
Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats
(2004) P. Chaturvedi; S. George; M. Milinganyo; Y.B. Tripathi
In this study, the methanol extract of Momordica charantia fruit extract was administered to diabetic rats to assess the long term effect of the extract on the lipid profile and the oral glucose tolerance test. Treatment for 30 days showed a significant decrease in triglyceride, low density lipoprotein and a significant increase in high density lipoprotein level. A significant effect on oral glucose tolerance was also noted. Chronic administration showed an improvement in the oral glucose tolerance curve. The effect was more pronounced when the test was done in rats fed the extract on the day of the test compared with tests done in rats which were not fed the extract on the same day. Copyright © 2004 John Wiley & Sons, Ltd.
Effect of Saussurea lappa alcoholic extract on different endocrine glands in relation to glucose metabolism in the rat
(1993) P. Chaturvedi; P. Tripathi; S. Pandey; U. Singh; Y.B. Tripathi
In this report the alcoholic extract of the root of Saussurea lappa C. B. Clarke (Compositae) has been used on albino rats to investigate the response on the histology of the thyroid gland, adrenal gland, pancreas and liver. Its effect on liver glycogen, blood glucose and plasma insulin has also been investigated. Treatment up to 7 days shows a significant hypoglycaemic response without an increase in plasma insulin. The acute response shows the accumulation of glycogen in the liver followed by its depletion. The histology of the thyroid shows stimulation. Liver sections do not show any toxic effects up to 400 mg/kg body weight. No change was observed in sections of adrenal gland and pancreas. Copyright © 1993 John Wiley & Sons, Ltd.
Hepatic Duct Stones Masquerading as Klatskin Tumour
(1999) V.K. Dixit; P. Chaturvedi; M. Pandey; A.K. Agarwal; V.K. Shukla
We report woman who presented with painless progressive jaundice following cholecystectomy. Radiological investigations indicated proximal bile duct obstruction suggestive of hilar malignancy. Exploratory laparatomy revealed bilateral hepatic duct stone causing obstruction.
Protective effect of Rubia cordifolia on lipid peroxide formation in isolated rat liver homogenate
(1994) S. Pandey; M. Sharma; P. Chaturvedi; Y.B. Tripathi
Rubia cordifolia Linn. (Rubiaceae) is an important component of the ayurvedic system of medicine. It has a variety of uses such as blood purifier, immunomodulant, antiinflammatoty and anti-PAF. In this report the anti-peroxidative property of the solvent free alcoholic extract of R. cordifolia has been studied in rat liver homogenate. It prevents the cumene hydroperoxide induced malondialdehyde formation in the dose and time dependent manner. This effect is accompanied by the maintained reduced glutathione level even in the presence of above toxin.
Thermotherapy of cloves for in-vitro mericlone production for healthy and sustainable management of garlic (Allium sativum L) germplasm
(National Institute of Science Communication and Policy Research, 2021) D.C. Manjunathagowda; K. Jayaswall; M. Singh; R. Sagar; P. Chaturvedi; V. Janhavi
Garlic is a second most important crop of the genus Allium, known for its traditional medicinal uses. In spite of having medicinal prosperities, it gets infected by several viruses called Garlic Viral Complex (GVC). The garlic viral complex severely affects bulb yield of garlic, due to accumulation of virus load year after year from asexual propagule cloves. Hence we attempted an experiment to eliminate garlic viral complex through thermotherapy in combination with meristem culture. The viruses were eliminated from infected garlic bulb with the treatment at 37°C for 90 days followed by meristem culture could eliminate the Garlic Common Latent Virus, Onion Yellow Dwarf Virus and Allexiviruses. In this study, we confirmed that the combination of thermotherapy and meristem culture technique protocol have wider prospects for virus elimination in garlic. © 2021, National Institute of Science Communication and Policy Research. All rights reserved.