Browsing by Author "P. Olliaro"
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PublicationArticle Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India(2009) P. Olliaro; S. SundarObjective and method To estimate drug costs of treating visceral leishmaniasis (VL) based on data on the VL population structure from the high-burden, antimony-resistant area of Northern Bihar, India. Results Paromomycin is the cheapest option ($7450 to treat 1000 patients). Treating 1000 patients with oral miltefosine would cost $119 250 at the current private market price or $64 383-$75 129 at preferential public sector price depending on the size of the order. With AmBisome ® it would be $163 600 or $229 500 depending on the dose (10 or 15 mg/kg total). These costs are without considering other direct costs (daily intramuscular injections for 3 weeks for paromomycin; intravenous devices and hospitalization for AmBisome®; directly observed treatment if applied for miltefosine) and indirect costs. Conclusion These calculations provide useful basic information for projections. © 2008 Blackwell Publishing Ltd.