Browsing by Author "P. Sharma"

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Clinical evaluation of diazepam for relief of postoperative pain
(Oxford University Press, 1981) P.N. Singh; P. Sharma; P.K. Gupta; K. Pandy
A double-blind trial was undertaken to compare the effects of trimeprazine tartrate (2mgkg-1 or 4mgkg-1) plus atropine 0.03mgkg-1 for oral preinedication of 192 children undergoing tonsillectomy. Demeanour before operation, side-effects after operation, recovery times and fluid balance were studied. Behaviour in the anaesthetic room and restlessness after operation were unaffected by the dose given. There was less vomiting associated with 4mgkg-1 compared with 2mg kg-1. Prolonged recovery times occurred frequently in the two groups, 14% in the small- and 17% in the large-dose groups taking more than 10 h to recover full mental faculties. Fluid bal4nce was unaffected by the dose and prolonged recovery did not result in a reduction of urine output. Trimeprazine tartrate is not recommended for routine premedication when early recovery is required. © 1981 Macmillian Publishers Ltd.
Comparison of intubating condition and cardiovascular effects after administration of rocuronium and vecuronium in children
(2008) Prithwis Bhattacharya; Shahbaz Ahmad; B.K. Behary; B.B. Kushwaha; P. Ranjan; P. Sharma
Background: Intubating conditions and cardiocascular effects of rocuronium and vecuronium were compared in children. Patients & Methods: The study was undertaken on 75 children aged 3-12 years of ASA grades I and II. They were randomly divided into three groups of 25 each. Group I (n=25) received bolus dose of vecuronium 0.1 mg kg-1, Group II received bolus dose of rocuronium 0.6 mg kg-1, and Group III received bolus dose of rocuronium 0.9 mg kg-1 as muscle relaxant to facilitate tracheal intubation. Comparison of intubating conditions and cardiovascular effects in all the three groups was done. Results: Vecuronium 0.1 mg kg-1 had a longer onset time than rocuronium 0.6 mg kg-1 and 0.9 mg kg -1, and provides better intubating conditions at 120 seconds. 0.9 mg kg-1 of rocuronium provides reliably excellent intubating conditions at 60 seconds than 0.6 mg kg-1 at 90 seconds. The changes in the hemodynamic parameters remained within clinically acceptable limits in all the three groups.
Enteropathogenicity of Plesiomonas shigelloides
(1980) S.C. Sanyal; B. Saraswathi; P. Sharma
Live cultures of 13 strains of Plesiomonas shigelloides isolated from different sources caused accumulation of fluid in rabbit ileal loops in the range 1-2 ml/cm of gut. Some strains required one or two passages in ileal loops before they gave a positive reaction. Inocula multiplied by c. 104-fold in the loops within the 6 h of the experiment. Maximal fluid accumulation was obtained with an inoculum of 104-105 colony-forming units. Culture filtrates, in volumes of 0.25 ml, also caused fluid accumulation comparable with that caused by live cells. The fluid accumulation started within 1-2 h, and showed a marked increase up to 4 h, with no appreciable change by 6-8 h, and a slight increase at 18 h. Heat treatment at 121°C for 10 min. did not affect the ability of filtrates to cause fluid accumulation. Suckling-mouse assay was positive for all the strains tested. The culture filtrates caused dislodgement of Chinese hamster ovarian and mouse adrenal tissue-culture cells from plate surfaces, or lysis of the cells. None of the strains caused keratoconjunctivitis in rabbit or guinea-pig eyes, and bacteria were not seen inside the epithelial cells of HeLa tissue cultures. The results of the investigation indicate the production of a heat-stable enterotoxin by P. shigelloides, while the elaboration of a heat-labile enterotoxin cannot be excluded. They do not suggest invasiveness. They give experimental support for an aetiological role for P. shigelloides in the production of diarrhoea, as has been previously suggested by epidemiological evidence.
Expanding neutrino oscillation parameter measurements in NOvA using a Bayesian approach
(American Physical Society, 2024) M.A. Acero; B. Acharya; P. Adamson; N. Anfimov; A. Antoshkin; E. Arrieta-Diaz; L. Asquith; A. Aurisano; A. Back; N. Balashov; P. Baldi; B.A. Bambah; A. Bat; K. Bays; R. Bernstein; T.J.C. Bezerra; V. Bhatnagar; D. Bhattarai; B. Bhuyan; J. Bian; A.C. Booth; R. Bowles; B. Brahma; C. Bromberg; N. Buchanan; A. Butkevich; S. Calvez; T.J. Carroll; E. Catano-Mur; J.P. Cesar; A. Chatla; S. Chaudhary; R. Chirco; B.C. Choudhary; A. Christensen; T.E. Coan; A. Cooleybeck; L. Cremonesi; G.S. Davies; P.F. Derwent; P. Ding; Z. Djurcic; M. Dolce; D. Doyle; D. Dueñas Tonguino; E.C. Dukes; A. Dye; R. Ehrlich; M. Elkins; E. Ewart; P. Filip; J. Franc; M.J. Frank; H.R. Gallagher; F. Gao; A. Giri; R.A. Gomes; M.C. Goodman; M. Groh; R. Group; A. Habig; F. Hakl; J. Hartnell; R. Hatcher; M. He; K. Heller; V. Hewes; A. Himmel; B. Jargowsky; J. Jarosz; F. Jediny; C. Johnson; M. Judah; I. Kakorin; D.M. Kaplan; A. Kalitkina; J. Kleykamp; O. Klimov; L.W. Koerner; L. Kolupaeva; R. Kralik; A. Kumar; C.D. Kuruppu; V. Kus; T. Lackey; K. Lang; P. Lasorak; J. Lesmeister; A. Lister; J. Liu; J.A. Lock; M. Lokajicek; M. Macmahon; S. Magill; W.A. Mann; M.T. Manoharan; M. Manrique Plata; M.L. Marshak; M. Martinez-Casales; V. Matveev; B. Mehta; M.D. Messier; H. Meyer; T. Miao; V. Mikola; W.H. Miller; S. Mishra; S.R. Mishra; R. Mohanta; A. Moren; A. Morozova; W. Mu; L. Mualem; M. Muether; K. Mulder; D. Myers; D. Naples; A. Nath; S. Nelleri; J.K. Nelson; R. Nichol; E. Niner; A. Norman; A. Norrick; T. Nosek; H. Oh; A. Olshevskiy; T. Olson; A. Pal; J. Paley; L. Panda; R.B. Patterson; G. Pawloski; O. Petrova; R. Petti; R.K. Plunkett; L.R. Prais; A. Rafique; V. Raj; M. Rajaoalisoa; B. Ramson; B. Rebel; P. Roy; O. Samoylov; M.C. Sanchez; S. Sánchez Falero; P. Shanahan; P. Sharma; A. Sheshukov; S. Shukla; D.K. Singha; W. Shorrock; I. Singh; P. Singh; V. Singh; E. Smith; J. Smolik; P. Snopok; N. Solomey; A. Sousa; K. Soustruznik; M. Strait; L. Suter; A. Sutton; K. Sutton; S. Swain; C. Sweeney; A. Sztuc; B. Tapia Oregui; P. Tas; T. Thakore; J. Thomas; E. Tiras; Y. Torun; J. Trokan-Tenorio; J. Urheim; P. Vahle; Z. Vallari; K.J. Vockerodt; T. Vrba; M. Wallbank; T.K. Warburton; M. Wetstein; D. Whittington; D.A. Wickremasinghe; T. Wieber; J. Wolcott; M. Wrobel; S. Wu; W. Wu; Y. Xiao; B. Yaeggy; A. Yankelevich; K. Yonehara; Y. Yu; S. Zadorozhnyy; J. Zalesak; R. Zwaska
NOvA is a long-baseline neutrino oscillation experiment that measures oscillations in charged-current νμ→νμ (disappearance) and νμ→νe (appearance) channels, and their antineutrino counterparts, using neutrinos of energies around 2 GeV over a distance of 810 km. In this work we reanalyze the dataset first examined in our previous paper [Phys. Rev. D 106, 032004 (2022)PRVDAQ2470-001010.1103/PhysRevD.106.032004] using an alternative statistical approach based on Bayesian Markov chain Monte Carlo. We measure oscillation parameters consistent with the previous results. We also extend our inferences to include the first NOvA measurements of the reactor mixing angle θ13, where we find 0.071≤sin22θ13≤0.107, and the Jarlskog invariant, where we observe no significant preference for the CP-conserving value J=0 over values favoring CP violation. We use these results to examine the effects of constraints from short-baseline measurements of θ13 using antineutrinos from nuclear reactors when making NOvA measurements of θ23. Our long-baseline measurement of θ13 is shown to be consistent with the reactor measurements, supporting the general applicability and robustness of the Pontecorvo-Maki-Nakagawa-Sakata framework for neutrino oscillations. © 2024 authors.
Fission time scale from pre-scission neutron and α multiplicities in the O 16 + Pt 194 reaction
(American Physical Society, 2017) K. Kapoor; S. Verma; P. Sharma; R. Mahajan; N. Kaur; G. Kaur; B.R. Behera; K.P. Singh; A. Kumar; H. Singh; R. Dubey; N. Saneesh; A. Jhingan; P. Sugathan; G. Mohanto; B.K. Nayak; A. Saxena; H.P. Sharma; S.K. Chamoli; I. Mukul; V. Singh
Pre- and post-scission α-particle multiplicities have been measured for the reaction O16+Pt194 at 98.4 MeV forming Rn210 compound nucleus. α particles were measured at various angles in coincidence with the fission fragments. Moving source technique was used to extract the pre- and post-scission contributions to the particle multiplicity. Study of the fission mechanism using the different probes are helpful in understanding the detailed reaction dynamics. The neutron multiplicities for this reaction have been reported earlier. The multiplicities of neutrons and α particles were reproduced using standard statistical model code joanne2 by varying the transient (τtr) and saddle to scission (τssc) times. This code includes deformation dependent-particle transmission coefficients, binding energies and level densities. Fission time scales of the order of 50-65 ×10-21 s are required to reproduce the neutron and α-particle multiplicities. © 2017 American Physical Society.
Hydatid disease in children may have an atypical presentation
(2000) A.N. Gangopadhyay; P. Sakti; S. Sahoo; P. Sharma; D.K. Gupta; C.K. Sinha; S.N. Rai
Although there is voluminous literature describing various aspects of hydatid disease in children, little attention has been paid to the small group of patients whose symptoms result in atypical presentation. This article addresses this problem, describing the features in ten children aged from 2 to 12 years. The sites of involvement were within a choledochal cyst (1). the pelvic cavity (1), the spleen (1), and transverse mesocolon. Albendazole was efficacious in the treatment of one recurrent case, as well as in preventing recurrence. © Springer-Verlag 2000.
In silico investigation on sensing of tyramine by boron and silicon doped C60 fullerenes
(Nature Research, 2023) S. Pattanaik; A.K. Vishwkarma; T. Yadav; E. Shakerzadeh; D. Sahu; S. Chakroborty; P.K. Tripathi; E.A. Zereffa; J. Malviya; A. Barik; S.K. Sarankar; P. Sharma; V.J. Upadhye; S. Wagadre
The present communication deals with the adsorption of tyramine neurotransmitter over the surface of pristine, Boron (B) and Silicon (Si) doped fullerenes. Density functional theory (DFT) calculations have been used to investigate tyramine adsorption on the surface of fullerenes in terms of stability, shape, work function, electronic characteristics, and density of state spectra. The most favourable adsorption configurations for tyramine have been computed to have adsorption energies of − 1.486, − 30.889, and − 31.166 kcal/mol, respectively whereas for the rest three configurations, it has been computed to be − 0.991, − 6.999, and − 8.796 kcal/mol, respectively. The band gaps for all six configurations are computed to be 2.68, 2.67, 2.06, 2.17, 2.07, and 2.14 eV, respectively. The band gap of pristine, B and Si doped fullerenes shows changes in their band gaps after adsorption of tyramine neurotransmitters. However, the change in band gaps reveals more in B doped fullerene rather than pristine and Si doped fullerenes. The change in band gaps of B and Si doped fullerenes leads a change in the electrical conductivity which helps to detect tyramine. Furthermore, natural bond orbital (NBO) computations demonstrated a net charge transfer of 0.006, 0.394, and 0.257e from tynamine to pristine, B and Si doped fullerenes. © 2023, The Author(s).
Induction of ascorbate and guaiacol specific peroxidases in metal and water deficit induced oxidative stress in rice seedlings
(2006) P. Sharma; A.B. Jha; S. Verma; R.S. Dubey
Plants possess two distinguished forms of peroxidases, namely ascorbate peroxidase (APX) and guaiacol peroxidase (GPX). The contribution of both forms was studied in rice seedlings as part of defense mechanism against water deficit as well as metal imposed oxidative stress. The metals Pb2+ and As3+ were freely absorbed by roots of rice plants from growth medium in sand cultures but were mainly localized in roots. Rice seedlings grown for 20 days in Hoagland nutrient solution in sand cultures containing either 500 μM and 1000 μM Pb2+, 80 μM and 160 μM Al3+ or 25 μM and 50 μM As3+ or when seedlings grown for 20 days in nutrient solution were subjected to 24 h water stress treatment of -0.5 MPa or -2.0 MPa showed elevated levels of lipid peroxides. Lipid peroxidation paralleled with increased APX activity in Pb2+, Al3+, As3+ as well as water stressed seedlings. Seedlings growing in presence of metal salts showed increased GPX activity, however GPX activity was higher in moderately water stressed (-0.5 MPa) seedlings and it declined with higher level (-2.0 MPa) of water stress. Induced activity of GPX and elevated level of lipid peroxidation were higher in roots compared to shoots however the induced activity of APX was higher in shoots. Two isoforms of APX when purified from leaves of 20 day grown rice seedlings showed very high affinity for H 2O2 and ascorbate and very little affinity for guaiacol. Activity staining in polyacrylamide gels revealed the induction of two new isoforms of GPX in roots of Al3+ as well as As3+ treated seedlings where as one new isoform of APX was induced in shoot of water and Al3+ stressed seedlings. Both ascorbate and guaiacol specific peroxidases appear to be important components of antioxidative defense mechanism under conditions of metal toxicity and water stress.
Joint neutrino oscillation analysis from the T2K and NOvA experiments
(Nature Research, 2025) Robert Miles Zwaska; Jaroslav Zalesak; S. Zadorozhnyy; Katsuya Yonehara; Alejandro Yankelevich; A. Yahaya; Barbara Yaeggy; Yiwen Xiao; Wanwei Wu; Shuai Wu; Jeremy A. Wolcott; Don Athula A. Wickremasinghe; D. W. Whittington; Matthew J. Wetstein; C. Weber; Thomas K. Warburton; Michael Wallbank; Abigail Victoria Waldron; K. J. Vockerodt; Z. Vallari; P. L. Vahle; Jon Urheim; J. Trokan-Tenorio; D. Tran; Yagmur Torun; M. Titus; Emrah Tiras; Jennifer A. Thomas; Tarak Thakore; P. Tas; N. Talukdar; Artur A. Sztuc; C. Sweeney; S. Swain; Andrew Sutton; Louise Suter; Matthew Strait; Karel Soustružník; Alexandre B. Sousa; Nickolas Solomey; Pavel V. Snopok; Jan Smolík; A. Smith; Dinesh Kumar Singha; Simranjit Singh Chhibra; Venktesh Singh; Prabhjot Singh; Ishwar Singh; Saurabh Shukla; W. Shorrock; Alexander K. Shmakov; Shivam; Andrey S. Sheshukov; P. Sharma; Peter Shanahan; S. Sánchez Falero; Mayly Calderón De La Barca Sánchez; O. B. Samoylov; P. K. Roy; Edgar E. Robles; Brian J. Rebel; Bryan J. Ramson; Miriama Rajaoalisoa; V. Raj; Aleena Rafique; L. R. Prais; J. C.C. Porter; Robert K. Plunkett; Roberto Petti; G. Pawloski; Ryan B. Patterson; Lipsarani Panda; Jonathan M. Paley; A. Pal; Mustafa Ozkaynak; T. Olson; Alexander G. Olshevskiy; H. Oh; A. Norrick; Andrew J. Norman; Evan Niner; Ryan J. Nichol; Jeffery K. Nelson; S. Nelleri; Donna L. Naples; D. Myers; Kevin Mulder; Mathew Muether; Leon Mualem; Wei Mu; A. D. Morozova; Adam Moren; Mohanta K. Rukmani; Sanjib Ratan Mishra; W. H. Miller; Ting Miao; Holger Meyer; M. D. Messier; Bhumika Mehta; Viktor A. Matveev
The landmark discovery that neutrinos have mass and can change type (or flavour) as they propagate—a process called neutrino oscillation1, 2, 3, 4, 5–6—has opened up a rich array of theoretical and experimental questions being actively pursued today. Neutrino oscillation remains the most powerful experimental tool for addressing many of these questions, including whether neutrinos violate charge-parity (CP) symmetry, which has possible connections to the unexplained preponderance of matter over antimatter in the Universe7, 8, 9, 10–11. Oscillation measurements also probe the mass-squared differences between the different neutrino mass states (Δm2), whether there are two light states and a heavier one (normal ordering) or vice versa (inverted ordering), and the structure of neutrino mass and flavour mixing12. Here we carry out the first joint analysis of datasets from NOvA13 and T2K14, the two currently operating long-baseline neutrino oscillation experiments (hundreds of kilometres of neutrino travel distance), taking advantage of our complementary experimental designs and setting new constraints on several neutrino sector parameters. This analysis provides new precision on the Δm322 mass difference, finding 2.43−0.03+0.04×10−3eV2 in the normal ordering and −2.48−0.04+0.03×10−3eV2 in the inverted ordering, as well as a 3σ interval on δCP of [−1.38π, 0.30π] in the normal ordering and [−0.92π, −0.04π] in the inverted ordering. The data show no strong preference for either mass ordering, but notably, if inverted ordering were assumed true within the three-flavour mixing model, then our results would provide evidence of CP symmetry violation in the lepton sector. © The Author(s) 2025.
Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021
(Elsevier Ltd, 2023) W.M. Gardner; C. Razo; T.A. McHugh; H. Hagins; V.M. Vilchis-Tella; C. Hennessy; H.J. Taylor; N. Perumal; K. Fuller; K.M. Cercy; L.Z. Zoeckler; C.S. Chen; S.S. Lim; A.Y. Aravkin; M.B. Arndt; J.D. Bishai; K. Burkart; E. Chung; X. Dai; L. Dandona; R. Dandona; S.D. Dharmaratne; M.A. Dirac; S.B. Ewald; R. Fitzgerald; M. Hassen; T. Mestrovic; A.H. Mokdad; H. Nassereldine; B.V. Pickering; R.J.D. Sorensen; J.D. Stanaway; P. Zheng; S.I. Hay; C.J.L. Murray; N.J. Kassebaum; A. Misganaw; A. Aali; M. Ghasemi Nour; A. Sahebkar; K.H. Abate; U. Gerema; A.T.T. Gizaw; S. Abd-Elsalam; A.M. Abdurehman; D.B. Enyew; B. Gebremichael; A.D. Kebede; H.A. Meresa; F. Weldegebreal; G. Abebe; Y.D. Abtew; T.K. Kanko; F.W. Demisse; B.T. Dora; E. Yisihak; S. Demissie; Y.H. Gebremariam; G.A. Wubetie; M. Woldemariam; H. Abidi; M. Zoladl; R.G. Aboagye; R.K. Alhassan; M. Immurana; H. Amu; E.E. Tarkang; H. Abolhassani; S. Alvand; S. Azadnajafabad; M. Azangou-Khyavy; S. Ghamari; M. Keykhaei; S. Momtazmanesh; S. Rahmani; M. Rashidi; N. Rezaei; K. Hosseini; E. Mahmoudi; S. Rashedi; F. Kompani; E. Malakan Rad; S. Masoudi; A. Sima; A. Nowroozi; M. Shafeghat; P. Shobeiri; F. Yazdanpanah; G.B. Aboye; M.M.K. Accrombessi; S. Shivalli; D.E. Adane; T.D. Adane; P. Vart; I.Y. Addo; V.R. Keshri; X. Xu; M.A. Adesina; I.I. Olufadewa; M. Ekholuenetale; A.F. Fagbamigbe; K.R. Fowobaje; S.E. Ibitoye; O.S. Ilesanmi; M.O. Owolabi; D.A. Adeyinka; Q.E.S. Adnani; M.S. Afzal; I. Ullah; N. Khalid; S. Afzal; R. Agustina; B.O. Ahinkorah; A. Ahmad; G. Mustafa; S. Ahmad; S. Ahmadi; M. Ajami; S. Doaei; M. Gholamalizadeh; E. Jamshidi; S. Sabour; M. Taheri; M. Zahir; A. Ahmed; T. Ahmed Rashid; W. Aiman; H. Akbarialiabad; A. Bashiri; Z. Zareshahrabadi; F. Alahdab; Z. Al-Aly; N. Alam; A. Alemayehu; M. Ali; S. Almustanyir; R.M. Al-Raddadi; Z.S. Natto; R.H. Al-Rifai; I. Elbarazi; M.A. Khan; K.A. Altirkawi; M. Temsah; Y.S.A. Amer; G.M.T. ElGohary; N. Alvis-Guzman; E.K. Ameyaw; T.F. Anagaw; M.B. Asresie; A.A. Awoke; D.G. Demsie; A.Y. Berhie; G.W. Dagnew; H.A. Guadie; R. Ancuceanu; M. Hostiuc; S. Hostiuc; I. Negoi; R.I. Negoi; A. Anoushirvani; S. Tabaeian; J. Arabloo; M. Dodangeh; D. Moosavi; A. Kabir; M. Noori; A. Tiyuri; M. Antwi; D. Anvari; S. Shorofi; H. Ariffin; T. Aripov; A.O. Oladunjoye; A. Arja; S.M. Legesse; B. Wagaye; J. Arulappan; R.T. Aruleba; T. Ashraf; A.A. Baig; A. Hanif; S. Athari; D. Atlaw; A. Aujayeb; M.A. Awoke; R. Holla; M.D. Janodia; M. Rahman; C.R. Rao; A. Badawi; Z.A. Bhutta; A.D. Badiye; N. Baghcheghi; N. Bagheri; S. Bagherieh; A. Fatehizadeh; M. Banach; P.C. Banik; A.T. Bantie; R.D. Barr; O.P. Kurmi; A.T. Olagunju; A. Barrow; S. Basu; A.M. Batiha; T. Begum; M. Moni; S.M. Billah; S.J. Hossain; M. Siraj; M. Tariqujjaman; M.A. Belete; F.M. Hussien; L. Belo; N. Cruz-Martins; I.M. Bensenor; A.C. Goulart; I.S. Santos; A.S. Bhagavathula; N. Bhardwaj; P. Bhardwaj; S. Misra; S. Singh; S.B. Varthya; A.N. Bhat; A. Boloor; H.L. Dsouza; J. Padubidri; B.K. Shetty; P.H. Shetty; N. Joseph; N. Kumar; R. Thapar; A. Shetty; B. Unnikrishnan; J.K. Das; Z.S. Lassi; B. Bikbov; S. Islam; H. Kandel; K. Nuruzzaman; S. Birara; S. Bitaraf; S. Sadeghian; J.S. Botelho; D. Calina; F. Cembranel; P.A. Chakraborty; G.S. Chanie; G. Dessie; M. Diress; Y. Gela; H.B. Eshetu; M.M. Sharew; W. Simegn; V. Chattu; J. Chien; I.S. Chukwu; M.H. Criqui; O. Dadras; H.A. Danawi; H. Kaur; A. Pandey; V.K. Kamal; A.M. Darwesh; M. Hosseinzadeh; A. Omar Bali; S. Das; V. De La Cruz-Góngora; F. Mejia-Rodriguez; H.D. Desai; M. Desalegn; B.R. Feyisa; G. Fekadu; F.N. Dessalegn; M. Dhimal; U. Paudel; S. Dhingra; D. Diaz; M. Didehdar; M. Golitaleb; M. Harorani; P.N. Doku; D. Dongarwar; H.A. Edinur; A.E.M. Elagali; M.A. Elbahnasawy; A.I. Hasaballah; A.M. Samy; M. Elhadi; W. El-Huneidi; B. Saddik; M.A. Elmonem; R. Ezzeddini; A. Mosapour; L. Zaki; S. Gaihre; A.O. Fasanmi; P. Ram; P.S. Suchdev; M.F. Young; J. Huang; F. Fischer; M. Foroutan; M.A. Gadanya; A.M. Gaidhane; Z. Quazi Syed; A. Gaipov; Y. Galali; D.K. Mohammad; N. Galehdar; P. Garg; M. Mirza; P. Singh; M. Verma; T. Garg; K.B. Gebremedhin; Z. Tamir; L. Getacher; G.B. Mulu; S.S. Yehualashet; K. Ghaffari; M. Ghafourifard; H. Hassankhani; M. Hosseini; A. Mahmoodpoor; M. Mirghafourvand; M. Rahimi; A. Ghashghaee; R. Kalhor; S. Ghozy; J.C. Glasbey; M. Golechha; P. Goleij; G.G. Goyomsa; M.I.M. Gubari; Z. Gudisa; D.A. Gunawardane; R. Gupta; I. Yunusa; S. Gupta; V.K. Gupta; A. Guta; Y. Solomon; A.A. Umer; P. Habibzadeh; S. Hamidi; A.J. Handal; M. Hannan; H. Harapan; M. Hasan; H. Hasani; K. Hayat; G. Heidari; S.Y. Hess; D.Z. Heyi; K. Hezam; Y. Hiraike; L.G. Vu; S. Hussain; I.M. Ilic; L.R. Inbaraj; N. Ismail; L.J. Bds; G. Kumar; D.K. Lal; U. Jayarajah; S. Jayaram; R. Jebai; B. Jemal; T. Muche; B. Seboka; G.A. Zenebe; A. Jeyakumar; R.P. Jha; J.B. Jonas; J.J. Jozwiak; L.R. Kalankesh; I.M. Karaye; F.Z. Kashoo; P.D. Katoto; J.H. Kauppila; A. Pathak; G.A. Kayode; Y.S. Khader; H. Khajuria; B.P. Nayak; M. Shannawaz; M. Khammarnia; H. Okati-Aliabad; I.A. Khan; K. Khatab; Z. Khazaei; M. Taheri Soodejani; J. Khubchandani; Y. Kim; R.W. Kimokoti; S. Kisa; S. Kosen; S. Koulmane Laxminarayana; K. Krishan; B. Kuate Defo; M. Kuddus; O. Kuti; I. Landires; A.O. Larsson; K. Latief; A. Laxmaiah; C. Ledda; M. Vacante; M. Veroux; S. Lee; X. Liu; I. Qattea; S. Sankararaman; L. Lorenzovici; V.S. Machado; J. Mendes; P.B. Mahajan; S. Mahjoub; T. Mallhi; D.C. Malta; S. Masoumi; J.C. Medina; W. Mendoza; O. Mendoza-Cano; A.A. Mentis; T. Miazgowski; A. Mirica; I. Petcu; S. Mohammadi; S. Mohammed; M.B. Sufiyan; S. Mohan; M. Shanawaz; N. Moka; L. Monasta; E. Mostafavi; F. Mulita; A. Musina; A.J. Nagarajan; T.S. Nair; S. Narasimha Swamy; P.M.S. Pradhan; S. Naz; R.Z. Raza; G. Nguefack-Tsague; J.W. Ngunjiri; R.K. Niazi; D. Nurrika; O.J. Nzoputam; B. Oancea; R.M. Obaidur; M.S. Obsa; Y. Sisay; J.N. Odhiambo; R.E. Ogunsakin; O.C. Okonji; O.O. Oladunjoye; A.E.E. Omonisi; A. Ortiz; R. Pakzad; T. Palicz; A. Pandya; P. Papadopoulou; S. Pardhan; J. Patel; A.R. Pathan; R. Paudel; S. Pawar; G. Pereira; N. Perico; G. Remuzzi; S. Perna; N. Perumalsamy; Z.Z. Piracha; R.C.G. Pollok; A. Prashant; F. Rahim; A. Rahman; A. Rahmani; R. Rai; I. Raimondo; S. Rajaa; J. Rana; M.A. Ranjha; S. Rao; S. Rawaf; L. Rawal; E.M.M. Redwan; M. Rezaei; T. Richards; J. Rickard; J.A.B. Rodriguez; L. Roever; G. Roshandel; A. Tahamtan; B. Roy; G.M. Rwegerera; A.M.A. Saad; M. Sadeghi; U. Saeed; H. Sahoo; M.R. Salem; R. Santoro; M. Satpathy; G. Saya; A.M. Senbeta; S. Senthilkumaran; A. Seylani; P.A. Shah; M.A. Shaikh; P. Sharma; R. Sheikhi; S.M. Shenoy; J.K. Shetty; J. Shin; V. Shivarov; M.K. Sikder; D. Vervoort; J.A. Singh; N.P. Singh; A.A. Skryabina; Y. Song; S. Sultana; M.D. Szeto; K. Tan; N.Y. Tat; Y.M. Tefera; A. Thiyagarajan; J.H.V. Ticoalu; B.M. Tigabu; R. Tobe-Gai; M.R. Tovani-Palone; M.T.N. Tran; B.S. Tusa; S. Valadan Tahbaz; P.R. Valdez; S. Vaziri; K. Yari; N.D. Wickramasinghe; T.E. Wonde; A. Yigit; V. Yiǧit; D. Yon; N. Yonemoto; C. Yu; Z. Zhang; B.A. Zaman; N. Zamora; I. Zare; M. Moradi
Background: Anaemia is a major health problem worldwide. Global estimates of anaemia burden are crucial for developing appropriate interventions to meet current international targets for disease mitigation. We describe the prevalence, years lived with disability, and trends of anaemia and its underlying causes in 204 countries and territories. Methods: We estimated population-level distributions of haemoglobin concentration by age and sex for each location from 1990 to 2021. We then calculated anaemia burden by severity and associated years lived with disability (YLDs). With data on prevalence of the causes of anaemia and associated cause-specific shifts in haemoglobin concentrations, we modelled the proportion of anaemia attributed to 37 underlying causes for all locations, years, and demographics in the Global Burden of Disease Study 2021. Findings: In 2021, the global prevalence of anaemia across all ages was 24·3% (95% uncertainty interval [UI] 23·9–24·7), corresponding to 1·92 billion (1·89–1·95) prevalent cases, compared with a prevalence of 28·2% (27·8–28·5) and 1·50 billion (1·48–1·52) prevalent cases in 1990. Large variations were observed in anaemia burden by age, sex, and geography, with children younger than 5 years, women, and countries in sub-Saharan Africa and south Asia being particularly affected. Anaemia caused 52·0 million (35·1–75·1) YLDs in 2021, and the YLD rate due to anaemia declined with increasing Socio-demographic Index. The most common causes of anaemia YLDs in 2021 were dietary iron deficiency (cause-specific anaemia YLD rate per 100 000 population: 422·4 [95% UI 286·1–612·9]), haemoglobinopathies and haemolytic anaemias (89·0 [58·2–123·7]), and other neglected tropical diseases (36·3 [24·4–52·8]), collectively accounting for 84·7% (84·1–85·2) of anaemia YLDs. Interpretation: Anaemia remains a substantial global health challenge, with persistent disparities according to age, sex, and geography. Estimates of cause-specific anaemia burden can be used to design locally relevant health interventions aimed at improving anaemia management and prevention. Funding: Bill & Melinda Gates Foundation. © 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
Search for CP -Violating Neutrino Nonstandard Interactions with the NOvA Experiment
(American Physical Society, 2024) M.A. Acero; B. Acharya; P. Adamson; L. Aliaga; N. Anfimov; A. Antoshkin; E. Arrieta-Diaz; L. Asquith; A. Aurisano; A. Back; N. Balashov; P. Baldi; B.A. Bambah; A. Bat; K. Bays; R. Bernstein; T.J.C. Bezerra; V. Bhatnagar; D. Bhattarai; B. Bhuyan; J. Bian; A.C. Booth; R. Bowles; B. Brahma; C. Bromberg; N. Buchanan; A. Butkevich; S. Calvez; T.J. Carroll; E. Catano-Mur; J.P. Cesar; A. Chatla; S. Chaudhary; R. Chirco; B.C. Choudhary; A. Christensen; M.F. Cicala; T.E. Coan; A. Cooleybeck; C. Cortes-Parra; D. Coveyou; L. Cremonesi; G.S. Davies; P.F. Derwent; Z. Djurcic; M. Dolce; D. Doyle; D. Dueñas Tonguino; E.C. Dukes; A. Dye; R. Ehrlich; E. Ewart; P. Filip; J. Franc; M.J. Frank; H.R. Gallagher; F. Gao; A. Giri; R.A. Gomes; M.C. Goodman; M. Groh; R. Group; A. Habig; F. Hakl; J. Hartnell; R. Hatcher; M. He; K. Heller; V. Hewes; A. Himmel; Y. Ivaneev; A. Ivanova; B. Jargowsky; J. Jarosz; C. Johnson; M. Judah; I. Kakorin; D.M. Kaplan; A. Kalitkina; J. Kleykamp; O. Klimov; L.W. Koerner; L. Kolupaeva; R. Kralik; C.D. Kuruppu; V. Kus; T. Lackey; K. Lang; J. Lesmeister; A. Lister; J. Liu; J.A. Lock; M. Lokajicek; M. Macmahon; S. Magill; W.A. Mann; M.T. Manoharan; M. Manrique Plata; M.L. Marshak; M. Martinez-Casales; V. Matveev; B. Mehta; M.D. Messier; H. Meyer; T. Miao; V. Mikola; W.H. Miller; S. Mishra; S.R. Mishra; A. Mislivec; R. Mohanta; A. Moren; A. Morozova; W. Mu; L. Mualem; M. Muether; K. Mulder; D. Myers; D. Naples; A. Nath; S. Nelleri; J.K. Nelson; R. Nichol; E. Niner; A. Norman; A. Norrick; T. Nosek; H. Oh; A. Olshevskiy; T. Olson; M. Ozkaynak; A. Pal; J. Paley; L. Panda; R.B. Patterson; G. Pawloski; O. Petrova; R. Petti; L.R. Prais; A. Rafique; V. Raj; M. Rajaoalisoa; B. Ramson; M. Ravelhofer; B. Rebel; P. Roy; O. Samoylov; M.C. Sanchez; S. Sánchez Falero; P. Shanahan; P. Sharma; A. Shmakov; A. Sheshukov; S. Shukla; D.K. Singha; W. Shorrock; I. Singh; P. Singh; V. Singh; E. Smith; J. Smolik; P. Snopok; N. Solomey; A. Sousa; K. Soustruznik; M. Strait; L. Suter; A. Sutton; K. Sutton; S. Swain; C. Sweeney; A. Sztuc; B. Tapia Oregui; P. Tas; T. Thakore; J. Thomas; E. Tiras; Y. Torun; J. Tripathi; J. Trokan-Tenorio; J. Urheim; P. Vahle; Z. Vallari; J. Vasel; J.D. Villamil; K.J. Vockerodt; T. Vrba; M. Wallbank; M. Wetstein; D. Whittington; D.A. Wickremasinghe; T. Wieber; J. Wolcott; M. Wrobel; S. Wu; W. Wu; Y. Xiao; B. Yaeggy; A. Yahaya; A. Yankelevich; K. Yonehara; Y. Yu; S. Zadorozhnyy; J. Zalesak; R. Zwaska
This Letter reports a search for charge-parity (CP) symmetry violating nonstandard interactions (NSI) of neutrinos with matter using the NOvA Experiment, and examines their effects on the determination of the standard oscillation parameters. Data from νμ(ν¯μ)→νμ(ν¯μ) and νμ(ν¯μ)→νe(ν¯e) oscillation channels are used to measure the effect of the NSI parameters Iµeμ and Iµeτ. With 90% CL the magnitudes of the NSI couplings are constrained to be |Iµeμ| 0.3 and |Iµeτ| 0.4. A degeneracy at |Iµeτ|≈1.8 is reported, and we observe that the presence of NSI limits sensitivity to the standard CP phase δCP. © 2024 authors.
Shape evolution in76,78Kr nuclei at high spins in tilted axis cranking Hartree-Fock-Bogoliubov approach
(2007) A. Ansari; P. Sharma; U.R. Jakhar; H.L. Yadav
A two-dimensional tilted axis cranking Hartree-Fock-Bogoliubov (CHFB) calculation is performed for 76Kr and 78Kr nuclei up to high spins J = 30 employing a pairing-plus-quadrupole (PPQ) model interaction Hamiltonian. Intricate details of the evolution of single particle structures and shapes as a function of spin have been investigated. The results show the existence of energy levels with high K quantum numbers lying close to the yrast line in both the nuclei. Such high K states should exhibit isomeric characteristics due to the K-selection rules for the γ-decays. Moreover, in 78Kr a new band with J = 20-30 lying below the observed ground band is predicted. © Indian Academy of Sciences.
Study of nuclear fusion-fission dynamics in 16O+194Pt reaction
(American Institute of Physics Inc., 2017) K. Kapoor; S. Verma; P. Sharma; R. Mahajan; N. Kaur; G. Kaur; B.R. Behera; K.P. Singh; H. Singh; R. Dubey; N. Saneesh; A. Jhingan; P. Sugathan; G. Mohanto; B.K. Nayak; A. Saxena; H.P. Sharma; S.K. Chamoli; I. Mukul; A. Kumar
Pre- and post-scission α-particle multiplicities have been measured for the reaction 16O + 194Pt at 98.4 MeV forming compound nucleus 210Rn. The α-particle's yield has been measured in coincidence with the fission fragments at various angles. The moving source analysis was performed to extract the alpha particle multiplicity which yielded the contribution of pre- and post- scission components. The pre-scission α-particle multiplicity has been compared with JOANNE2 statistical model code predictions to extract fission time scale and which is observed to be around 55zs (1zs=10-21s). © 2017 Author(s).
Vaccination saves lives: a real-time study of patients with chronic diseases and severe COVID-19 infection
(Oxford University Press, 2023) A. Mukherjee; G. Kumar; A. Turuk; A. Bhalla; T.C. Bingi; P. Bhardwaj; T.D. Baruah; S. Mukherjee; A. Talukdar; Y. Ray; M. John; J.R. Khambholja; A.H. Patel; S. Bhuniya; R. Joshi; G.R. Menon; D. Sahu; V.V. Rao; B. Bhargava; S. Panda; P. Mishra; Y. Panchal; L.K. Sharma; A. Agarwal; G.D. Puri; V. Suri; K. Singla; R. Mesipogu; V.S. Aedula; M.A. Mohiuddin; D. Kumar; S. Saurabh; S. Misra; P.K. Kannauje; A. Kumar; A. Shukla; A. Pal; S. Chakraborty; M. Dutta; T. Mondal; S. Chakravorty; B. Bhattacharjee; S.R. Paul; D. Majumder; S. Chatterjee; A. Abraham; D. Varghese; M. Thomas; N. Shah; M. Patel; S. Madan; A. Desai; M.L. Kala Yadhav; R. Madhumathi; G.S. Chetna; U.K. Ojha; R.R. Jha; A. Kumar; A. Pathak; A. Sharma; M. Purohit; L. Sarangi; M. Rath; A.D. Shah; L. Kumar; P. Patel; N. Dulhani; S. Dube; J. Shrivastava; A. Mittal; L. Patnaik; J.P. Sahoo; S. Sharma; V.K. Katyal; A. Katyal; N. Yadav; R. Upadhyay; S. Srivastava; A. Srivastava; N.N. Suthar; N.M. Shah; K. Rajvansh; H. Purohit; P.R. Mohapatra; M.K. Panigrahi; S. Saigal; A. Khurana; M. Panchal; M. Anderpa; D. Patel; V. Salgar; S. Algur; R. Choudhury; M. Rao; D. Nithya; B.K. Gupta; B. Kumar; J. Gupta; S. Bhandari; A. Agrawal; M. Shameem; N. Fatima; S. Pala; V. Nongpiur; S. Chatterji; S. Mukherjee; S.K. Shivnitwar; S. Tripathy; P. Lokhande; H. Dandu; A. Gupta; V. Kumar; N. Sharma; R. Vohra; A. Paliwal; M. Pavan Kumar; A. Bikshapathi Rao; N. Kikon; R. Kikon; K. Manohar; Y. Sathyanarayana Raju; A. Madharia; J. Chakravarty; M. Chaubey; R.K. Bandaru; M. Ali Mirza; S. Kataria; P. Sharma; S. Ghosh; A. Hazra
Objectives: This study aims to describe the demographic and clinical profile and ascertain the determinants of outcome among hospitalized coronavirus disease 2019 (COVID-19) adult patients enrolled in the National Clinical Registry for COVID-19 (NCRC). Methods: NCRC is an on-going data collection platform operational in 42 hospitals across India. Data of hospitalized COVID-19 patients enrolled in NCRC between 1st September 2020 to 26th October 2021 were examined. Results: Analysis of 29 509 hospitalized, adult COVID-19 patients [mean (SD) age: 51.1 (16.2) year; male: 18 752 (63.6%)] showed that 15 678 (53.1%) had at least one comorbidity. Among 25 715 (87.1%) symptomatic patients, fever was the commonest symptom (72.3%) followed by shortness of breath (48.9%) and dry cough (45.5%). In-hospital mortality was 14.5% (n = 3957). Adjusted odds of dying were significantly higher in age group ≥60 years, males, with diabetes, chronic kidney diseases, chronic liver disease, malignancy and tuberculosis, presenting with dyspnoea and neurological symptoms. WHO ordinal scale 4 or above at admission carried the highest odds of dying [5.6 (95% CI: 4.6–7.0)]. Patients receiving one [OR: 0.5 (95% CI: 0.4–0.7)] or two doses of anti-SARS CoV-2 vaccine [OR: 0.4 (95% CI: 0.3–0.7)] were protected from in-hospital mortality. Conclusions: WHO ordinal scale at admission is the most important independent predictor for in-hospital death in COVID-19 patients. Anti-SARS-CoV2 vaccination provides significant protection against mortality. © The Author(s) 2022.