Browsing by Author "P.B. Singh"

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A decade's experience with vesicovaginal fistula in India
(Springer London, 2007) Neeraj K. Goyal; U.S. Dwivedi; N. Vyas; M.P. Rao; S. Trivedi; P.B. Singh
A retrospective analysis of 252 cases of vesicovaginal fistulae was done to analyse its etio-pathology and management in an Indian population. After a thorough evaluation, different techniques of fistula closure were used for repair and the results were listed. The main outcome measures were the etiology of the fistula, need for tissue interposition and cure rate per repair as well as the overall cure rate. We compared our results with literature and concluded that simple and small fistulae should be repaired with layered closure. All complicated fistulae should be repaired with tissue interposition or tissue graft. This is the first study from India compiling 10 years of experience on vesicovaginal fistula. © International Urogynecology Journal 2006.
Angiogenesis and histologic scoring in prostatic carcinoma - A valuable cost effective prognostic indicator
(2004) M. Kumar; V. Tandon; P.B. Singh; S. Mitra; N. Vyas
Objective: To find any correlation between microscopic angiogenesis grading system (MAGS) score and Gleason score and serum prostate specific antigen (S.PSA) in carcinoma of prostate. Study design: Examination of 30 patients with prostatic carcinoma compared with an age matched control group of 30 patients having histopathologically proven benign prostatic Hyperplasia. The Preoperative serum PSA level was determined in all patients. Histopathological examination for MAGS score was done in all patients and Gleason scoring was done for cases of prostatic carcinoma. Result: MAGS score had a definite correlation with Gleason score (Correlation coefficient, r = 0.84, p = 0.008). Studying the relationship between MAGS score and S.PSA, a statistically significant difference is found between S.PSA levels in study and control groups, and in the three MAGS score groups namely 21-30, 31-40 and 41-50. Conclusion: Gleason score and MAGS score are well related to each other. As tumor becomes more poorly differentiated with rising Gleason score, it would also have increased number of capillaries and higher grade endothelial cytology leading to a higher MAGS score.
Anuria in advanced carcinoma of prostate: Role of methyl prednisolone - A case report
(2003) Vibhav Malviya; Gopi Kishore; Arif Hameed; U.S. Dwivedi; P.B. Singh
[No abstract available]
Artificial neural networks in predicting optimum renal stone fragmentation by extracorporeal shock wave lithotripsy: A preliminary study
(2003) A. Hamid; U.S. Dwivedi; T.N. Singh; M. Gopi Kishore; M. Mahmood; H. Singh; V. Tandon; P.B. Singh
OBJECTIVE: To assess the ability of artificial neural networks (ANNs) to predict optimum renal stone fragmentation in patients being managed by extracorporeal shock wave lithotripsy (ESWL). PATIENTS AND METHODS: The study included 82 patients with renal stones who were being treated by ESWL. Data (input and output values) from 60 patients in whom there was optimum fragmentation of stones by ESWL were used for training the ANN. These data mainly included the 24-h urinary variables, the radiological features of the stone disease and the ESWL settings used. The predictability of the trained ANN was tested on 22 subsequent patients, by supplying the input variables of the 22 patients into the trained ANN and recording the output values (predicted values). After subjecting these patients to ESWL, the actual results (observed values) were recorded. The predicted and the observed values were then compared. RESULTS: In the 22 patients in whom predictability was tested, the trained ANN predicted optimum fragmentation at ≤13 000 shocks/stone (as per study protocol) in 17 and optimum fragmentation at >13 000 shocks/stone in the other five. In the 17 patients (test set) where the trained ANN had predicted optimum fragmentation at ≤13 000 shocks/stone, the optimum fragmentation was at that value, although the predicted and observed values were not identical. The overall correlation between the predicted and the observed values was 75.5% (correlation coefficient 0.7547) in these 17 patients. Of the other five patients, none had optimum fragmentation at <13 000 shocks/stone, as predicted by the trained ANN, giving complete accuracy for this factor. CONCLUSION: This was a pilot study, i.e. an initial attempt to use an ANN in this regard, and although there were few patients, such that it is not possible to make final recommendations, the overall predictability was ≈75%. An encouraging outcome of the study was that the trained ANN identified patients unlikely to benefit from ESWL. Using a larger dataset and identifying more significant variables, while eliminating inputs with a negative effect, the efficiency and utility of this ANN can probably be enhanced and in future it might be possible to predict stone fragmentation with reasonable accuracy.
Avulsion Injuries Of Penis
(Georg Thieme Verlag, 2024) Anand Kumar; P.B. Singh; N.N. Khanna
[No abstract available]
Blunt renal injury-an experience of 30 cases
(1986) P.B. Singh; S.S. Ambasta; V.N.P. Tripathi; R. Agrawal; M. Singh; S. Vajpeyi
Thirty cases of blunt renal injury are reviewed. The need for rapid and accurate diagnosis of these cases with excretory urography, supplemented in certain patients with renal angiography, is discussed. High-dose excretory urography allows the cases to be categorized into minor or major injuries. All minor injuries can be managed without operation. For major injuries, a conservative approach, if necessary followed by surgical exploration, avoids loss of organ in most of the cases. © 1986.
Clinical value of fine needle aspiration cytology and biopsy in the evaluation of male infertility... A comparative study of 60 infertile patients
(2004) Mufti Mahmood; Jagdishwar Kumar Singh; U.S. Dwivedi; Mohan Kumar; P.B. Singh
To compare the diagnostic value of cytological smears of fine needle aspirate with that of histological sections obtained by testicular biopsy in the evaluation of infertility, 60 patients of infertility with azoospermia and severe oligospermia (sperm counts of <5 million/ml) were undertaken for the study. A detailed history was taken and the duration and type of infertility whether primary or secondary was noted. A thorough general physical examination included the examination of the genitalia. Testicular samples were obtained by fine-needle aspiration using a 10 ml syringe and 21-gauze needle. The samples were fixed in 95% alcohol and stained with papanicoloau stain. A testicular biopsy was taken after exploring the same tract and these sections were stained with haematoxylin and eosin. The cytological smears and histological sections were examined separately and the results compared. The cytological smears were divided into four groups: normal, with all spermatogenic cells present, hypospermatogenesis; spermatogenic arrest and sertoli cell only syndrome. There was 95% correlation between the diagnosis on the cytological smears and histological sections. However, there was some discrepancy in hypospermatogenesis and maturation arrest groups, they being difficult to diagnose even on histology.
Color Doppler ultrasonography: Its role in detection and treatment outcome in infravesical obstruction
(2003) Saleem Wani; Arif Hamid; M. Gopi Kishore; Vibhav Malviya; U.S. Dwivedi; P.B. Singh
Bladder weight and detrusor blood perfusion increases significantly with infravesical obstruction (IVO) and release of obstruction results in reduction of bladder weight and detrusor blood flow. 38 patients with IVO were subjected to color Doppler ultrasonography (CDU) to detect the blood flow in the hypertrophied detrusor-muscle. Blood flow was detected in 84.5% (Fisher exact probability <0.001). After surgical relief of obstruction, blood flow remained positive in 21.05% patients at 3 months and 13.10% patients at 6 months, which was because of persistence of IVO. Color Doppler ultrasonography (CDU) is a simple and non-invasive tool which can help in diagnosis and follow-up of infravesical obstruction.
Combined augmentation ileo-cystoplasty and ileal replacement of ureter in advanced genitourinary tuberculosis: Modified technique
(2002) P.B. Singh; Harbans Singh; Arif Hamid; Gopi Kishore; U.S. Dwivedi
An advanced case of genitourinary tuberculosis presenting with small capacity bladder, left ureteric stricture and nonfunctioning right kidney was managed with modified technique of combined augmentation ileo-cystoplasty and ileal replacement of left ureter. This complex and extensive reconstruction can be done easily and successfully in a short time with our modified technique.
Congenital Mucus Retention Cyst of Penis Presenting as Skin Papilloma
(2007) Neeraj Kumar Goyal; S. Trivedi; U.S. Dwivedi; P.B. Singh
[No abstract available]
Current role of trans rectal ultrasonography (TRUS) of prostate
(2001) Wani M. Saleem; P.B. Singh; U.S. Dwivedi
[No abstract available]
Dorsal onlay buccal mucosal graft urethroplasty in long anterior urethral stricture
(Brazilian Society of Urology, 2007) Biswajit Datta; M.P. Rao; R.L. Acharya; N. Goel; Vaibhav Saxena; S. Trivedi; U.S. Dwivedi; P.B. Singh
Objective: To assess the success of buccal mucosal graft (BMG) urethroplasty by the dorsal onlay technique in long anterior urethral stricture (> 2 cm long) through the midline perineal incision. Materials and Methods: From January 1998 to December 2003, 43 patients with long anterior urethral strictures were managed by dorsal onlay BMG urethroplasty. After voiding trial, they were followed up at 3 months with uroflowmetry retrograde urethrogram (RGU) and American Urological Association symptoms score (AUA symptoms scores). Successful outcome was defined as normal voiding with a maximum one attempt of VIU after catheter removal. Patients were further followed-up with uroflowmetry at 3 months interval and RGU every 6 months interval. Results: Mean stricture length was 4.8 cm (range 3 to 9 cm) and mean follow up was 48 months (range 12 to 84 months). Only five patients were found to develop stricture at anastomotic site, during follow-up. Two of them voided normally after single attempt of VIU. Other three patients (6.9%) required further open surgery or repeat VIU during follow up and were considered as failure. Conclusion: Dorsal onlay BMG urethroplasty is a simple technique with good surgical outcome.
Experience With Vaso-Vasostomy: Technique And Result
(Georg Thieme Verlag, 2024) P.B. Singh; Hemant Kumar; S.S. Ambasta; V.N.P. Tripathi
Fifteen patients underwent recanalization procedure by single layer non magnified anastomosis with splint. In 12 patients (807%) reappearance of sperm was found with sperm count ranging from 5-6/H.P.F. to 40 million/ml. No side effect was observed due to splint. © 2024 Georg Thieme Verlag. All rights reserved.
Fat-soluble vitamin profile in filarial chyluria - A preliminary study
(1999) M. Sridhar; D.K. Pal; I.D. Saxena; U.S. Dwivedi; V.N.P. Tripathi; P.B. Singh
[No abstract available]
Filarial chyluria: Long-term experience of a university hospital in India
(2004) Vipul Tandon; Harbans Singh; U.S. Dwivedi; Mufti Mahmood; P.B. Singh
Background: Filariasis is an endemic problem in various Indian states. We evaluated the results of long-term follow up (10-20 years) of patients with filarial chyluria. Methods: We conducted a retrospective analysis of 160 patients treated for filarial chyluria who presented to the Banaras Hindu University Hospital from 1982 to 1992. Eighty-four patients (52.5%) were treated using diethylcarbamazine (DEC) and a fat restricted diet and 76 patients (47.5%) underwent surgery. To examine the long-term effects of filarial chyluria we analysed data on post-treatment recurrence, weight gain, dietary freedom, chyluria free period and a number of other associated factors. Results: Previous history of filariasis or its complication was documented in 19% of patients. In 71% of cases, cystoscopy showed that chylous efflux was predominant in the left ureteric orifice. The long-term remission rate was 62% in the conservatively managed group (DEC + fat restricted diet), whereas 90% of patients in the operated group were cured. Postoperative recurrence rate was 10%. There was more weight gain and dietary freedom along with a longer chyluria free period in the operated group relative to the conservatively managed group. Conclusions: Definitive surgical ablation of lymphatic urinary fistula is better than conservative medical management because it has a higher success rate, more dietary freedom and, therefore, better patient acceptability.
Fine needle aspiration cytology in the diagnosis of prostatic enlargements.
(1992) N.C. Aryya; R.K. Yadav; P.B. Singh; S. Khanna; K. Pandey
One hundred patients with enlarged prostate were subjected to fine needle aspiration cytology and histopathologic examination of prostate. The results have been found encouraging. The cytodiagnostic accuracy rate was 99 p.c. in identification of benign or malignant nature of the lesions and 94 p.c. in cytologic specific diagnosis (exactly similar to histopathologic diagnosis). The technique was simple, rapid, economical, reliable, easy to repeat and highly suitable for outpatients. The procedure can routinely be adopted in places where facilities for preparation of paraffin section do not exist or when quick diagnosis is required.
Foreign body in bladder: A diagnostic dilemma
(2005) Mufti Mahmood; Vipul Tandon; U.S. Dwivedi; P.B. Singh
Foreign bodies in bladder being unusual in the clinical setting present as a diagnostic dilemma with the history being vague as highlighted by the present case of a 28 years old female who was found to have multiple long rubber tubings coiled together in the bladder. Cystoscopic retrival was not possible as the rubber tubings had formed a huge coiled mass. The tubings were removed by a suprapubic cystostomy. Postoperative period was uneventful.
Ileal neo-bladder: A decade experience with "pouch first and ileal neo-urethra": Our modification
(2004) P.B. Singh; Mufti Mohmood; Vipul Tandon; M. Prasada Rao; Nachiket Vyas; P.R. Nandy; Biswajeet Dutta; U.S. Dwivedi
Objective: To show the efficacy and ease of our modified technique of constructing orthotopic neo-bladder after radical cystectomy for carcinoma bladder. Materials and methods: A total number of 76 patients with invasive carcinoma of bladder underwent radical cystectomy and orthotopic neo-bladder construction at this tertiary care hospital. We modified the conventional Hautman's technique. In this we constructed the ileal pouch first on the abdominal surface after making a neo-urethra utilizing a "U" shaped flap of dependent ileal segment. Then at the end of the procedure, anastomosis is performed between the neo-urethra and the membranous urethra. These cases are followed up at regular intervals with usual protocols with special stress on uroflowmetry and complete urodynamic assessment in selected patients. Results: Out of 76 patients who had a follow up of more than 10 years, only 1 patient developed total incontinence, which developed early local recurrence. Day and night time continence rates were achieved in 95 and 90%, respectively. All patients have shown good urodynamic characteristics and normal upper tracts without vesicoureteral reflex. Conclusion: This new modified technique of making the pouch first on the surface with urethral anastomosis as a last step avoids accidental disruption, offers technical simplicity and substantially shorterns the operative time. This makes the procedure safer even in the hands of less experienced urologists without compromising continence rates.
Impact of malathion and γ-BHC on steroidogenesis in the freshwater catfish, Heteropneustes fossilis
(1992) P.B. Singh; T.P. Singh
Female H. Fossilis were exposed to sublethal concentrations of an organophosphorus (malathion, 5 and 20 μl/l)and an organochlorine (γ-BHC. 4 and 16 mg l) pesticide for 4 weeks during different phases of the annual reproductive cycle. The impact of these pesticides on plasma levels of sex steroids, viz. testosterone (T). estradiol-17β (E2), estrone (E1) and 17α-hydroxyprogesterone (17α-OHPg) were monitored by radioimmunoassay. T levels showed an insignificant decrease at 5 μl l malathion during postspawning and resting phases, whereas it showed a significant reduction during the remaining phases by both pesticides of either concentrations. There was an insignificant decrease in E2 levels at 5 solμl l malathion during the preparatory phase. None of the pesticides could alter the E2 levels during the postspawning phase, whereas a significant decrease was found for both concentrations during preparatory, prespawning and spawning phases. Both pesticides reduced the levels of E1 during preparatory, prespawning and spawning phases whereas there was no impact during the postspawning phase by these pesticides. Except for 5 μl l malathion during the preparatory phase, both pesticides of either concentrations reduced the levels of 17α-OHPg during preparatory, prespawning and spawning phases. Both pesticides caused a greater reduction in sex hormone levels at higher concentrations. γ-BHC was more effective than malathion. It was concluded that malathion and γ-BHC had toxic effects on sex steroid metabolism and disturbed steroid regulation, resulting in hormonal imbalance. © 1992.
Impact of γ-BHC on lipid class levels and their modulation by reproductive hormones in the freshwater catfish, Heteropneustes fossilis
(Springer-Verlag, 1992) P.B. Singh; T.P. Singh
[No abstract available]