Browsing by Author "P.C. Sen"

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A comparative evaluation of levamisole in leprosy
(1985) L. Sharma; G.H. Thalliath; H.S. Girgia; P.C. Sen
[No abstract available]
A modified medium for testing sensitivity to tetracycline by diffusion technique
(1973) P.C. Sen; D.P. Chakrabarty; Hardas Singh
[No abstract available]
Accumulation of serotonin in human cerebral contusion
(1978) S. Mohanty; P.K. Dey; P.C. Sen; A. Ray
Brain tissue from ten patients with gross evidence of brain contusion and edema following trauma was examined for serotonin content by histofluorescent examination. There was evidence of an accumulation of serotonin and its diffusion towards the surrounding tissues in contusions.
Alpha-fetoprotein levels in some complications of pregnancy
(1983) L.K. Pandey; Priyadarshi; P.C. Sen
[No abstract available]
Anaerobic infections of the skin and soft tissues
(1981) N.N. Khanna; P. Jain; P.C. Sen
Five cases of anaerobic infection of the skin and subcutaneous tissues have been presented. While the first three cases were diagnosed as progressive bacterial synergistic gangrene, the fourth was diagnosed as synergistic necrotising cellulitis and the last case as a non-clostridial crepitant cellulitis. All these cases needed energetic treatment. Mortality is high, particularly in synergistic necrotising cellulitis. In all cases, an aggressive debridement of the wound by excision through the adjoining healthy tissue, intensive antimicrobial therapy with penicillin and metronidazole and vigorous supportive measures to correct anaemia, electrolyte derangements and associated diseases may help to salvage some of these otherwise hopeless cases.
Antibiotic resistance in Shigella
(1979) R.S. Rao; S.C. Sanyal; P.C. Sen
82 strains of Shigella isolated at Varanasi were tested for their susceptibility to 12 currently used antibiotics by the disc agar-diffusion technique. A maximum number of strains (56.1%) were resistant to demeclocycline and the resistance to doxycycline was detected in 52.4% of strains. Resistance to chlorotetracycline, oxytetracycline, demeclocycline and doxycycline was detected in 19.5% of strains. Streptomycin-resistance was found in 29.3% of strains and 50% of these were Sh.dysenteriae. A few strains were resistant to chloramphenicol, ampicillin, furazolidone, co-methoxazole and gentamycin. No resistance to kanamycin or neomycin was found.
Antitoxoplasma antibody in clinically suspected cases of human toxoplasmosis.
(1990) S. Kar; M.R. Sen; A.N. Gangopadhyay; P.C. Sen
(1) Seventy sera from a variety of patients suffering from different diseases suspected to be caused by Toxoplasma gondii infection and forty from non-toxoplasmic hospital cases and laboratory and hospital staff were collected. (2) Antitoxoplasma antibody was detected in those sera by Indirect Haemagglutination test (IHA test) and Enzyme Linked Immunosorbent Assay (ELISA). (3) Twenty one (30%) sera out of 70 test samples and 2 (5%) out of 40 control samples were positive by ELISA test. With IHA test only 17 (24.3%) of test samples and same 2 (5%) of control samples were positive. (4) Sera collected from Paediatric Department showed the highest positivity (40%) followed by Opthalmological group (35.7%) and obstetrics and Gynaecological group (13.6%). (5) No significant co-relation was found between the seropositivity with sex, diet and history of cat contact of the patients.
Association of pulmonary tuberculosis and cryptococcosis
(1974) V.K. Jha; P.C. Sen; M. Joshi; K. Kotilingam
[No abstract available]
Bacteriological study in osteo articular tuberculosis
(1976) V.P. Lakhanpal; H. Singh; P.C. Sen; S.M. Tuli
One hundred and five specimens were submitted for culture for acid fast bacilli, positive cultures were obtained in 49.53% of cases, when 20.95% of specimens which were contaminated were counted as negative. Excluding contaminated materials, culture for acid fast bacilli was positive in 62.65% of cases. In this study cultures were incubated for 20 weeks. Seventy three per cent of the positive cultures appeared within 8 weeks, 27% of the positive cultures appeared when incubated between 8 and 20 weeks. There were 14 cultures which were positive during the first 4 weeks, these patients had had no antitubercular drugs before this investigation. Out of the positive cultures 90.38% were typical Mycobacterium tuberculosis, 9.62% were chromogens, one of which was in association with typical Mycobacterium. Out of typical Mycobacterium tuberculosis 16.66% were found to be resistant to streptomycin only, 12.5% were resistant to P.A.S. only, 20.83% were resistant to I.N.H. alone and 8.33% were resistant to thiacetazone exclusively. All chromogenic acid fast bacilli were resistant to all the first line anti tubercular drugs streptomycin, P.A.S., I.N.H. and to thiacetazone.
Bacteriological study of Ganges water at Varanasi
(1976) D.K. Agarwal; S.D. Gaur; P.C. Sen; S.M. Marwah
[No abstract available]
Cell-mediated immune responses in tumour-free Indian patients
(1980) S. Gupta; S.K. Seth; K.N. Udupa; P.C. Sen
[No abstract available]
Cellular immunity status in anaemia in pregnancy.
(1991) A. Kandoi; B.D. Bhatia; L.K. Pandey; S. Pandey; P.C. Sen; K. Satya
Fifty pregnant women (25 anaemic and 25 non-anaemic) and 20 non pregnant women (10 anaemic and 10 non-anaemic) were studied. All pregnant women delivered full term (37-41 wk) singleton babies. Maternal blood lymphocyte stimulation indices (SI) at 0 and 24 h were lower in anaemic and non-anaemic pregnant women, compared to anaemic and non-anaemic non-pregnant women. This difference was more marked in anaemic pregnant women, as compared to non pregnant anaemic women at 0 and 24 h respectively. The SI of maternal and cord blood lymphocytes were significantly lower in severely anaemic mothers both at 0 and 24 h and in those with maternal serum iron levels below 50 micrograms/dl or maternal per cent transferrin saturation was below 15 per cent. The anaemic mothers and their offspring were found to have significantly lower blastogenic response to PHA added at 24 h indicating depression of T-suppressor cell function.
Circulating immune complexes and complement in bancroftian filariasis.
(1991) G. Nath; T.M. Mohapatra; P.C. Sen
Sixty filarial cases, 30 endemic normal individuals and 10 non endemic subjects were investigated for the presence of Circulating Immune Complexes (CICs) and Complement Component C3. Using Polyethylene Glycol precipitation and Polyethylene Glycol precipitation-Complement Consumption methods, it was observed that CICs were raised significantly in chronic lymphatic filariasis and Tropical Pulmonary Eosinophilia (TPE) groups. The results observed by both the techniques for detection of CICs were comparable. Low levels of C3 were detected in chronic lymphatic filariasis cases by single radial immunodiffusion method, suggesting the utilization of complement by immune complexes.
Clinico-radiological follow-up study of empyema thoracis in children [2]
(1996) O.P. Mishra; B.K. Das; A.K. Jain; T.K. Lahiri; P.C. Sen; V. Bhargava
[No abstract available]
Colistin and genticyn in the treatment of Pseudomonas corneal ulcer
(1974) P.N. Roy; K.S. Mehra; P.C. Sen
It was observed experimentally that the efficacy of the combination of colistin and gentamicin is more or less the same as seen with individual drugs. There is neither an inhibitory effect nor a synergistic effect on combining the 2 medicines, colistin and gentamicin, in causing healing of corneal ulcer. The culture of the eyes, in which colistin plus gentamicin were used together became sterile much earlier than the eyes in which individual drops were used.
Comparative evaluation of Thayer Martin medium and Chacko Nair medium in the isolation of gonococci
(1975) K.G. Pillai; H.S. Girgla; P.C. Sen
Urethral discharge from 36 male patients clinically suspected to be suffering from gonorrhoea and cervical and urethral swabs from 10 female contacts were examined by gram stained smear and parallel cultures on Thayer Martin medium and Chacko Nair medium to evaluate the comparative efficacy of the two media in the isolation of N. gonorrhoeae. The culture results on the two media agreed in 97.8%. The other results are presented and discussed. It is felt that in the prevalent Indian conditions Chacko Nair medium is superior in cost effectiveness and availability.
Delayed cutaneous hypersensitivity and blood lymphocyte count in advanced Hodgkin's and non-Hodgkin's lymphomas
(1980) S. Gupta; S.K. Seth; K.N. Udupa; P.C. Sen; B.L. Rastogi
Cell-mediated immune status was assessed in twenty patients of advanced and active lymphoreticular malignancies and twenty control subjects of comparable age and sex distribution by delayed cutaneous hypersensitivity responses to recall and contact antigens and peripheral blood lymphocyte counts. The results show depressed cellular immunity in both Hodgkin's and non-Hodgkin's lymphoma patients. However, the severity of immunological dysfunction as shown by anergy to skin antigens and lymphocytopenia is remarkably less than what has been mostly reported in the literature.
Delayed cutaneous hypersensitivity and peripheral blood lymphocyte counts in gastrointestinal cancer
(1980) S. Gupta; S.K. Seth; K.N. Udupa; P.C. Sen
Cell-mediated immune responses as expressed by delayed cutaneous hypersensitivity (DCH) reactions to specific recall antigens (PPD and BCG) and non-specific contact antigen (DNCR), and peripheral blood lymphocyte counts were studied in 60 patients with gastrointestinal cancer and 20 control subjects. The pattern of these immune responses in gastrointestinal cancer was significantly different from tumour-free control subjects of comparable age and sex distribution and apparently indicates a depressed immunologic function in cancer patients. Our study suggests that DNCB skin testing and peripheral blood lymphocyte counts are relatively simple and reliable investigations for predicting the advanced stage of gastrointestinal cancer (and BBY implication prognosis).
E-rosetting cells in amoebic liver abscess
(1981) D.P. Acharya; P.C. Sen
[No abstract available]
Effect of exogenous 5-hydroxytryptamine on pathogenicity of Entamoeba histolytica in experimental animals
(1989) D.P. Acharya; M.R. Sen; P.C. Sen
[No abstract available]