Browsing by Author "P.R. Gupta"

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A study of clinical presentation and delays in management of acute myocardial infarction in community
(Elsevier B.V., 2012) Pravin K. Goel; Saurabh Kumar Srivastava; Fauzia Ashfaq; P.R. Gupta; P.C. Saxena; Rajeev Agarwal; Sudeep Kumar; Naveen Garg; Satyendra Tewari; Aditya Kapoor
To assess the medico social demographics of acute myocardial infarction (AMI) in our community we studied 609 patients presenting between January 2008 to December 2008 with a detailed questionnaire in four centres of UP. Medical attention was sought late (> 6 hours) in 316 (51. 6%), thrombolysis was obtained in 45. 2% (275) and presentation was atypical in 16. 3% (99). 36. 2% (221) had pre-monitory symptoms of which 68% (150) ignored the same while of 32% (71) who did seek medical attention 47. 9% (37) were brushed away as non-cardiac in origin. 20. 3% (46/226) of hy- pertension, 23. 2% (43/185) of diabetes and 83. 4% (91/109) of hyperlipidaemia was diagnosed post event. We conclude that at least half of patients with AMI do not get definitive therapy, at least one in 10 patients do not have the classical symptoms, reasonable proportion are unaware of their risk factors, and a good majority have pre-monitory symptoms which get overlooked. © 2012, Cardiological Society of India. All rights reserved.
Adverse effects of oral amiodarone therapy.
(1992) P.R. Sinha; S. Dube; Sujata; P.R. Gupta; P. Avasthey; P.N. Somani
Oral amiodarone was administered to 38 patients (25 males, 13 females) with mean age of 43.6 years. Ventricular and supraventricular arrhythmias were present in 30 and 8 patients respectively. Amiodarone was given as 400-1200 mg/day for 1-2 weeks as loading dose and then it was maintained as 100-600 mg/day. The mean duration of therapy was 12.4 months. Adverse effects were noted in 21 (55.3%) cases. The commonest adverse effects observed were asymptomatic corneal microdeposits followed by gastrointestinal, cardiac, neurological and cutaneous disturbances. The drug was withdrawn in 2 (5.3%) patients because of nausea and vomiting. One patient died of pulmonary infiltrations. It is concluded that adverse effects are common with amiodarone but are tolerated well, making this drug an excellent choice for treatment of cardiac arrhythmias.
Cardiac changes in acute viral hepatitis in Varanasi (India): Case reports
(1989) D.S. Singh; P.R. Gupta; S.S. Gupta; P.K. Bhatia; P.N. Somani; I.S. Gambhir; A.K. Khare
Three cases of acute viral hepatitis are reported with various cardiac changes such as transient left ventricular hypertrophy, myocarditis and progressive cardiomegaly (cardiomyopathy). Extra-hepatic manifestations of acute viral hepatitis are rare but have been well documented. The aims of the present study are to highlight the cardiac involvement in acute viral hepatitis and to report the clinical implications of cardiac changes in acute viral hepatitis.
Chronic atrial fibrillation reverting to sinus rhythm following thumpversion in a case of rheumatic heart disease.
(1990) P.R. Gupta; P.R. Sinha; P.N. Somani
[No abstract available]
Cor-triatriatum with atrial septal defect and bicuspid aortic valve diagnosed by cross-sectional echocardiography.
(1990) P.R. Gupta; P.R. Sinha; P. Avasthey
We report a rare case with a combination of cor-triatriatum, large secundum atrial septal defect and bicuspid aortic valve. The diagnosis was made by cross-sectional echocardiography. A defect was present between proximal (accessory) left atrial chamber and right atrium decompressing the accessory left atrial chamber. The large left to right shunt resulted in severe pulmonary arterial hypertension.
Corrected QT interval (QTc) and its relationship with fatal ventricular tachyarrhythmias and sudden death in acute myocardial infarction
(1984) P.R. Gupta; A. Kumar; V.P. Singh; B.V. Agrawal; P. Awasthey; P.N. Somani
[No abstract available]
Diastolic collapse of both atria in patients of cardiac tamponade: report of two cases.
(1992) P.R. Sinha; P.R. Gupta; P. Avasthey
[No abstract available]
Evaluation of oral dipyridamole electrocardiography test in ischaemic heart disease
(1997) P.R. Gupta; P. Avashty; A.K. Garg; P.V.S.S. Srinivas Prasad
Forty-three cases of ischaemic heart disease of the age group 35-72 yrs with positive treadmill test (TMT) results were administered dipyridamole in the morning on empty stomach. Heart rate, BP and ECG were recorded before and every 15 mins after oral dipyridamole upto 2 hrs. ECG was repeated every 5 mins when patients developed angina or ischaemic ECG changes. Oral dipyridamole electrocardiography test (ODET) was found to be positive in 21 (48.83%) cases and majority of them developed ST depression in 25-40 mins and persisted for less than 30 mins. While compared with TMT results patients having chest pain, lower target heart rate (< 75%), shorter time to onset (< 2 mins) of ST depression and longer duration (> 8 mins) of ST depression had significantly higher rates of positivity on ODET than those without these manifestations. There were minor changes in hemodynamic parameter (heart rate, systolic and diastolic blood pressure) and other minor side effects encountered include mild headache and benign unifocal VPCs. Oral dipyridamole is viewed as a safe drug and may be used as a substitute for TMT specially in economically poor and physically disabled patients with significant coronary artery disease.
Patterns and determinants of dyslipidaemia in 'Young' versus 'Not so Young' patients of coronary artery disease: A multicentric, randomised observational study in northern India
(Elsevier B.V., 2012) Nakul Sinha; Sudeep Kumar; Himanshu Rai; Neha Singh; Aditya Kapoor; Satyendra Tewari; R.K. Saran; V.S. Narain; R.P.S. Bharadwaj; R.K. Bansal; P.C. Saxena; P.R. Sinha; P.R. Gupta; Mukul Mishra; Praveen Jain; C.M. Pandey; Uttam Singh; S.S. Agarwal
Aims: The aims of the study were to ascertain difference in lipid levels of 'Young' onset of coronary artery disease (CAD) (≤ 45 years) vs. 'Not so Young' onset of CAD (≥ 55 years) among north Indians and also to investigate determinants of 'dyslipidaemia' in CAD patients. Methods: This was a prospective, multicentric, randomised, observational study carried in eight cen- tres of UP, India. All blood investigations were performed employing a central laboratory. Results: Out of a total 435 patients studied, 218 were in the 'young group' (YG) and 235 were in the 'Not so Young Group' (NSYG). Dyslipidaemia was more common in YG as evident by significantly higher levels of total cholesterol, triglycerides, low- and very low-density lipoprotein cholesterol as compared to NSYG. Diabetes, hypertension, urban lifestyle, and family history of CAD were found to be important determinants of dyslipidaemia in YG. Conclusion: We conclude that lipid levels among north Indians are significantly higher in younger patients with CAD when compared with elderly. © 2012, Cardiological Society of India. All rights reserved.
Ruptured sinus of valsalva into right ventricle : A unique case with prolonged survival
(2006) P.R. Gupta; R. Tewari; A.K. Singh; A. Kumar
[No abstract available]
Twin immunologic test (TIT) in myocardial infarction. A reliable laboratory index
(1989) R.M. Gupta; P. Awasthey; B.V. Agrawal; P.R. Gupta; S. Usha; V. Ja iswal
[No abstract available]
Two-dimensional echocardiographic detection of biventricular thrombi in a case of idiopathic dilated cardiomyopathy
(1993) P.R. Sinha; S.S. Agrawal; P.R. Gupta
A man aged 50 years presented with a 6-month history of exertional dyspnea and palpitation with features of congestive heart failure. Echocardiography demonstrated biventricular apical thrombi. There was no episode of thromboembolism. The patient was treated with warfarin and was doing well at the time of this study.