Browsing by Author "P.S. Byadgi"

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A critical analysis of satmya with special reference to madhumeha (Type-2 diabetes mellitus) and certain biochemical parameters
(J. K. Welfare and Pharmascope Foundation, 2019) P.S. Byadgi; Santosh Kumar Ranjan; N.S. Tripathi
Ayurveda is an ancient medical science that deals with the well being of the human being as well as measures to treat diseases. There are two main purpose of Ayurveda, first being to maintain the healthy status of the healthy people and the second one is to cure the disease of the unhealthy person. For the diagnosis of the disease, ancient Acharyas have given much importance of knowledge obtained by Pratyaksha (direct perception), Anumana (inference), Aptopadesha (testimony), and Yukti (reasoning) during the examination of the patient for a successful treatment. To fulfill this purpose, Atura-Pariksha (examination of patients) Dravya Pariksha (examination of medicinal drug and preparations) and Roga-Rogi Pariksha (examination of the patient and disease) etc. are a very important tool. The concept of Satmya is described under Dashavidha Atura Pariksha (tenfold examination), and it is an important concept in both Swastha-rakshana (maintenance of health) and Aturasya Vikara Prashamana (treatment of disease). The concept of Satmya is explained by different Acharyas elaborately in their own way. The process of adopting Satmya from Asatmya is well explained in the classics. To evaluate the significance of Satmya pariksha in Madhumeha (T2DM) patients. Assessment of Satmya status and biochemical parameters in Madhumeha (T2DM) patients. Satmya might be an important tool for the assessment of the strength of patient and also helpful for proper planning of treatment. © 2019, J. K. Welfare and Pharmascope Foundation. All rights reserved.
A randomised clinical trial evaluating effectiveness of Guduchi and Shunthi kvatha in Amavata(Rheumatoid arthritis) in comparison with indomethacin
(J. K. Welfare and Pharmascope Foundation, 2020) Daneshwari S. Kanashetti; P.S. Byadgi; K.N. Dwivedi
Indian Traditional system of medicine (Ayurveda) has played premier role in the management of crippling disease, Amavata is one among them. Amavata is a chronic disease caused by vitiation of Vata associated with Ama. The clinical presentation of Amavata closely mimic Rheumatoid arthritis in accordance with their similarities in clinical features like pain, swelling, stiffness, fever, general debility, fatigue, etc. Herbal drugs are becoming increasingly popular in managing chronic diseases because of its safety, long term usage with fewer side effects and multidimensional actions. Guduchi (Tinospora cordifo-lia (Willd.) Miers ex Hook.f. & thoms.) and Shunthi (Zingiber officinale Rosc.) are widely available economic drugs with effective pharmacological actions. Present clinical study is conducted on 3 groups with 27 patients in each group. Patients of group 1 were administered the test form i.e, Guduchi and Shunthi kvatha. Patients of group 2 were treated with standard drug Indomethacin 75 mg BD. Patients of group 3 were administered both with Guduchi & Shunthi kvatha and Indomethacin. The results were tabulated using statistical meth-ods and compared between the groups. Change in subjective and objective parameters were observed at the end of treatment in each group. Subjective parameters like Pain, Angamarda, Aruchi, Trishna, Alasya, Gaurava, Jvara, Apaka and Shunata anganam were observed. Objective parameters like CBC, ESR, RA factor, CRP and collagen profile were carried out before and after treatment. Trial drug shows more efficacy in alleviating subjective parame-ters, but standard drug shows more efficiency in the form of objective param-eters. Overall effectiveness in signs and symptoms was seen in the volun-teers taking both trial and standard drug which signifies synergistic effect of both drugs help in resolution of Amavata better. Guduchi and Shunthi kvatha showed encouraging results but this must be taken for longer duration. © International Journal of Research in Pharmaceutical Sciences.
Clinical assessment of sara and blood investigations in Madhumeha (T2DM)
(J. K. Welfare and Pharmascope Foundation, 2020) Santosh Kumar Ranjan; P.S. Byadgi; N.S. Tripathi
Pratyaksha (direct perception), Anumana (inference), Aptopadesha (testi-mony), and Yukti (reasoning) are the tools that helps for the diagnosis of the disease. To fulfill this purpose Atura-Pariksha (examination of patients), Dravya Pariksha (examination of medicinal drug and preparations), and Roga-Rogi Pariksha (examination of the patient and disease), etc. are a very important tool. The concept of Sara is described under Dashavidha Atura Pariksha (tenfold examination), and it is an important concept in both Swastha-rakshana (maintenance of health) and Aturasya Vikara Prashamana (treat-ment of disease). The concept of Sara is explained by different Acharyas elaborately in their own way. In spite of tremendous success in modern medical science, the incidence of diseases are increasing enormously. A sedentary lifestyle and improper dietary habits has led to the emergence of several health problems, including Type 2 Diabetes Mellitus (T2DM), and it is emerging as a major disease affecting mankind with many complications. Hence present study has been undertaken to understand Sara because all persons vary from one another in many ways, and a personalized approach to patient care should be adopted to plan appropriate therapeutics. Dietary factors, lifestyle, and psychological factors are involved in the aetiology of Madhumeha (T2DM). The Twak Sara, ShukraSara, AsthiSara, and Majja Sara persons are more prone to develop Madhumeha (T2DM). The Meda Sara and Mamsa Sara are less prone to develop Madhumeha (T2DM). We don’t find the Rakta Sara individuals in our study. © 2020 International Journal of Research in Pharmaceutical Sciences. All rights reserved.
Clinical assessment scales for the Kostha
(J. K. Welfare and Pharmascope Foundation, 2020) Neera Saini; Pradeep Kumar Pal; S.K. Shukla; Rakesh Kumar Singh; P.S. Byadgi
The present clinical study is planned to develop a scale to assess the Kostha. Kostha is accredited in the scriptures as Mahasrotas (the great channel), Sharira Madhya (central section of the body), Mahanimna (the inmost part of the body) and Amapakvashaya (stomach and intestines). The term Kostha is expressed in the context of bowel habit and clinically it is classified into three types Mridu, Madhyama and Krura. Regarding the assessment of Kostha.i.e. bowel habit should be examined considering the frequency, consis-tency, straining during defecation etc. Randomly 60 healthy cases were regis-tered for the assessment of Kostha. A self developed 10-items was introduced earlier and 9-items in the final scale. Mean, Median, Standard deviation, higher and lower values etc. of total score were calculated. The reliability of the scale was calculated by administering Cronbach-alpha, was found 0.835, indicating higher reliability of the test. Construct validity of the test was determined by finding coefficient of correlation between scores and reliability of the scores. It was found 0.913 & it indicates higher validity. © International Journal of Research in Pharmaceutical Sciences. All rights reserved.
Clinical correlation of Amavata with arthropathies
(Innovare Academics Sciences Pvt. Ltd, 2017) Neera Saini; N.K. Singh; P.S. Byadgi
Objective: The objective of the study was to evaluate the disease Amavata with current understanding of International Classification of Diseases (ICD) 2010. Methods: For the present clinical study, a total of 100 patients were selected. Selection of the patients was done using subjective criteria (mentioned in Ayurvedic samhitas) to diagnose Amavata. Moreover, these patients were classified into three stages according to duration (<6 months, more than 6 months, more than 1 year) of disease. Laboratory investigations were advised such as hematological parameters and collagen profile. Results: A total of 100 cases of Amavata were divided into two groups based on ICD classification 2010. 86 cases of Amavata patients were diagnosed as rheumatoid arthritis including all the three stages. 14 cases of Amavata were diagnosed as systemic lupus erythematosus, reactive arthritis, and ankylosing spondylitis including all the three stages. Conclusion: Amavata is a syndrome may be correlated to arthropathies described under ICD classification 2010. © 2017 The Authors.
Clinical evaluation of Virechan therapy and Haridradi Vati and oil for the management of Kitibh Kushtha (Psoriasis)
(International Journal of Research in Ayurveda and Pharmacy, 2013) Satyapal Singh; P.S. Byadgi; N.P. Rai
It is generally an accepted concept in medicine that the skin can develop signs of internal disease. in reality, concise differential diagnosis and the identification of these disorders are actually difficult for the nondermatologist because he or she is not well-versed in the recognition of cutaneous lesions or their spectrum of presentations. the skin is the largest organ of our body. it is one of the five 'gyanendriyas' as described in ayurvedic texts, which is responsible for 'sparsha gyan' or touch sensation. therefore, it plays a major role in physical and mental well being of any individual. in ayurveda, all the skin disease has been described under the umbrella of kushtha. they are further classified into mahakushtha and kshudrakushtha. according to charaka kitibh is vat-kapha predominant and according to sushruta, it is pitta predominant kshudrakushtha. kitibh kushtha may be correlated to psoriasis due to their more or less similar clinical presentations. therefore, in this clinical trial we have planned to study the clinical effect of virechan therapy (for elimination of pitta) and haridradi vati and oil (for samshaman of vat-kapha) in kitibh kushtha. kitibh kushtha is characterized by patches which are blackish brown in colour, rough and coarse in nature, exudative, round, thick along with severe itching. psoriasis is one of the most common dermatologic diseases affecting up to 2.5% of the world's population. it is a non-infectious chronic inflammatory skin disorder clinically characterised by pink-red, silvery scale, sharply demarcated lesions on the skin surface especially over elbows, knees, scalp and presacral areas. present clinical study comprises of randomly selected eighteen registered cases of psoriasis (kitibh kushtha ) from opd and ipd of kayachikitsa, sir sundarlal hospital, b.h.u.,varanasi, have been treated with virechan therapy and haridradi vati and oil (containing haridra , bakuchi , guduchi and gomutra) to assess the clinical efficacy of virechan and these ayurvedic remedies. significant changes in subjective and objective criteria were observed. however, no significant changes observed in respect to haematological, biochemical, urine examination and stool examination.
Concept of immunity in Ayurveda
(2011) P.S. Byadgi
Resistance to diseases or immunity against diseases is of two kinds i.e. the one which attenuate the manifested disease and other variety prevents the manifestation of diseases. During certain conditions, or due to c ertain factors, even unwholesome food does not produce diseases immediately. All unwholesome food articles are not equally harmful, all dosas are not equally powerful, and all persons are not capable of resisting diseases. Over obese individual; over emaciated person; whose muscles and blood are diminished markedly; debilitated person; one who consumes unwholesome food; one who consumes less amount of food; whose mental faculties are weak; on the oth er hand, individuals having opposite type of physical constitution are capable of resisting diseases. Factors which contribute for vyadhikshamatva are normal dosa, equilibrium state of dhatu, normal agni, patency of srotas etc. or factors which supports the equilibrium state of all physiological parameters. Innate immunity may be correlated to sahaja bala described in Ayurveda. K alaja anad yuktikrita bala may be correlated to acquired immunity. Present article through light on the concept of immunity vis-a vis vyadhiksamatwa. Author has collected many references regarding how to enhance immunity and keep body disease free by adopting ayurvedic principles.
Critical review of ritu (seasons) with special reference to current research
(2012) Singh Pramod; N.S. Tripathi; P.S. Byadgi
The aim and objectives of Ayurveda is of two fold i.e. 1.Prevention of health in healthy individual 2.Cure of the disease in diseased person. To fulfill the first aim different Acharayas have described dincharya, ritucharya, sadvritta etc. In Brihatrayi there is separate description/chapters for ritucharya. Having second aim in mind Acharya's have mentioned relation of seasons and disease and different types of formulations are also advised according to season. To overcome effect of season ritucharya (seasonal regimen) is advocated in Ayuveda. So it is relevant to review the description available in the ayurvedic text books in relation to ritu (season).One should follow dietetic regimen and activities as ascribed in Ayurveda in respective seasons to maintain the normal health. Present article through some glimpses on season vis-à-vis ritu on health and disease.
Importance of ayu pareeksha for the management of diseases
(Journal of Clinical and Diagnostic Research, 2017) Agrawal Monika; P.S. Byadgi; B.K. Dwibedy
The word Ayurveda comes from the Sanskrit root Ayu which means span of life. The purpose of examination of Ayu is to obtain knowledge regarding longevity, residual span of life in diseased person and rate of the mortality. The purpose of Dashavidha Pariksha is to obtain knowledge regarding Dosha Bala (Vyadhi Bala), Bala (Rogibala) and Ayu of the patient as described in Charak Samhita. Commonly Ayu and Vaya are regarded as synonyms but they are not similar terms. Hence, description of Vaya and Ayu is separately mentioned in Charaka as well as Sushruta Samhita. Description exclusively on Ayu Pareeksha described in Charaka Viman Sthana, Charaka Chikitsasthana, Charaka Indriya Sthana and Charaka Shareer Sthana. In Indriya Sthana, Ayu Pariksha indicates the residual life-span of the diseased person and where as in Jaatisutriya Adhyaya in Shareer Sthana mentioned the characteristic properties of the child who is going to survive for longer period of time. In Sushruta Samhita, Ayu is classified into three broad headings namely Dirghayu, Madhyamayu and Alpayu and explained the characteristic properties of all the three. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.
Importance of seasonal regimen with special reference to impact on physiological parameters
(2012) Pramod Kumar Singh; P.S. Byadgi; N.S. Tripathi
Season is divided into six parts and each part consists of two months. Seasons also classified to eliminate the morbidity of Doshas in the respective seasons. Strength of the person is highest in visarga kala in comparison to adana kala. Different life style and dietetic regimen advised for each seasons. Time of seven days at the end and commencement of the season is known as ritusandhi. It is critical period in which previous regimen should be discontinued gradually and that of subsequent season should be adopted gradually. Seasons influences on body humours resulting into aggravation, accumulation and pacification. Hence one should prescribe appropriate biopurificatory procedures, collect drugs etc. to lead a healthy life.
Management of COVID-19: Ayurvedic perspective
(National Institute of Science Communication and Information Resources, 2020) Y.B. Tripathi; N. Joshi; S.K. Dubey; P.S. Byadgi; S. Bhat; R. Prasad; B.K. Dwivedi; K.K. Pandey; J.S. Tripathi; C.S. Pandey; K.H.H.V.S.S.N. Murthy; S. Suman; A.K. Pandey; V. Srivastava; V. Jaisawal; K.N. Dwivedi
Ayurveda, a branch of AYUSH system of health care in India is considered as alternative/complementary of medicine (CAM) in WHO. Here, its products are covered under “drug and cosmetics” act but in abroad they are supplements or functional foods. The aim of Ayurveda is to maintain the wellness of a healthy person and to treat a patient. For treatment, Ayurveda adopts 3 approaches i.e., (1) Daivavyapasharya chikitsa) (ypareht enivid 2 ( Yuktivyapashraya chikitsa (Rational therapy) 3 Satvavajaya chikitsa (Psychotherapy) and focuses to enhance the Vyadhikshmatwa (capacity to fight against spread of pathogenesis by strengthening all 7 dhatus (rasa, rakta, meda, mansa, asthi, majja and shukra). The disease COVID-19 falls under “Bhootvidya (GrahaVidya)", which is one of the 8 branches of “Astanga Ayurveda”. It is an “Agantuja” disease, where the disease symptoms appear in 1st stage followed by its spread in the body. Thus, progress of disease (Samprapti) has been considered under concept of shatkriyakala (6 stages of disease development), which has been given high importance for deciding the stage of disease progress and its treatment protocol. Here, we have described the introduction to Astang Ayurveda, concept of disease pathogenesis and holistic approach of treatment in respect to management of COVID-19. It specifically covers symptom based stage of disease progress and its targeted treatment guideline by including all 3 approaches of treatment, described above. Here, the current line of diagnosis, treatment and research related to COVID-19 management has been included, which are reported by basic scientists and physicians of allopathic system. These are indexed in Pubmed and web of science and also described in classical text books of Ayurveda. The same has been reviewed and summarized here, with an objective of possible correlation between the 2 languages of science of health care. © 2020, National Institute of Science Communication and Information Resources. All rights reserved.
Sunthi (Dry Zingiber Officinale) as a Prophylactic Agent Against SARS-CoV-2 Transmission and COVID-19 Symptomatology: Evidence From a Non-randomised Single-Arm Study
(Elsevier GmbH, 2023) S.K. Dubey; S.K. Mishra; V. Singh; Y.B. Tripathi; R.N. Chaurasia; P.S. Byadgi; H. Jani; R. Mishra; N. Joshi; T.B. Singh; A. Kumar; A. Yadav; A. Jaiswal
Introduction: Ancient Indian medical system Ayurveda cites Sunthi (an ayurvedic preparation of dry Zingiber officinale) as ‘Vishvabhesaja’—medicine of highest relevance for the whole world—upholding its special status in managing pandemics. The present study assessed the prophylactic response of Sunthi in reducing SARS-CoV-2 transmission, moderating COVID-19 symptomatology, and improving individuals’ quality of life. The COVID-19-relevant phytochemicals in Z.officinale were analysed, and the prominent predictive factors for quality of life were identified. Methods: This study used multicentre, non-randomised, open-label, single-arm, pre-post design. The sample (n = 824) comprised household members of hospitalised coronavirus-infected patients (n = 770) and the frontline health care workers (n = 54) operating in COVID-19 hospitals. Participants consumed Sunthi powder four times daily, twice via oral (2 g) and twice via nasal (0.5 g) routes, for 15 days. They were followed up after 15, 30, and 90 days. For phytochemical analysis, liquid chromatography coupled with mass spectrometry, and for data analysis, McNemar's test, repeated measures t-test, and multiple linear regression were performed. Results: Z.officinale comprises phytoconstituents with anti-SARS-CoV-2 properties, has no severe effects, alleviates coronavirus-compatible symptoms, and improves the quality of life. Conclusions: Dry Z.officinale can be a safe, effective, readily deployable, and affordable treatment for preventing coronavirus infection and managing COVID-19 symptomatology. Incorporating it into the COVID-19 prevention and management protocol can be of relevance for public health systems globally. However, this is a preliminary observation that may be informative for future research. No causal inference pertaining to the observed association could be drawn, and this result shall be interpreted with caution. © 2023 Elsevier GmbH
Sushruta: A great surgeon and visionary of Ayurveda
(2012) Paliwal Murlidhar; P.S. Byadgi
Ayurveda is described as science of life and it was recalled by Brahma as mentioned in Ayurvedic treatises. Brahma transformed his noble knowledge to Prajapati or Daksha, later Daksha passed his legacy to Ashwins and Indra received knowledge from Aswins. As per Sushruta opinion, Indra taught Ayurveda to Dhanvantari, the surgeon of gods embodied as king Divodasa of Banaras (Kashiraja). Divodasa then transmitted medical knowledge with special reference to surgery to the wise men like Sushruta and others who approached him as pupils, out of sympathy for the suffering humanity and also in order to prolong their own life. This school of thoughts is known as Dhanvantara-Sampradaya i.e. the school of surgery. All the fellows of Sushruta and Sushruta himself composed texts on the base of the perceptions of the teacher Divodasa Dhanvantari. Sushruta composed 'Sushruta-Samhita' which is fully available till now and is considered the best book for Sharira. Nagarjuna redacted the Sushruta-Samhita and possibly added Uttaratantra in 5th century A.D. In 10th century Chandrata, son of Tisata did the Pathashuddhi and renewed the Sushruta-Samhita on the basis of commentary done by Jejjata. In due course of time, many commentaries in Sanskrit, Hindi and English were written which show the growing acceptance and utility of the text. Charaka-Samhita, Sushruta-Samhita and Samhitas of Vagbhata are considered as Brihat-trayee i.e. three main treatises. In Kshemakutuhala text, it is well versed that a Vaidya who has listened many more text books but not listened the Sushruta-Samhita is devoid of actual benefits and if studied many other books but not the Charaka-Samhita gets defame or criticism among Vaidyas who have studied both the Samhitas. Vagbhata says that if the texts written by seers and sages get recognition in society then except Charaka-Samhita and Sushruta-Samhita why Bhela-Samhita etc. are not studied. All these references prove the gravity of Charaka-Samhita and Sushruta-Samhita. Sushruta-Samhita has unique position and contributions in the field of Ayurveda especially anatomy and surgery. Sushruta elaborates many surgical procedures like Nasa-Sandhana, Karnapali-Sandhana, Siravedha, Vranopakrama, treatment of Asthibhagna and Sandhibhagna etc. which is indicative of his excellent surgical skills. Hence Sushruta is regarded as the father of surgery. He was educated at Kashi in India and mentions the places of India in his text mainly southern portion which is suggestive of the view that he was a native of this country.
The role of psychological factors in aetiopathogenesis and management of obesity related diseases
(2011) J.S. Tripathi; P.S. Byadgi; K. Narasimha Murthy
The obesity is a challenging problem in to-days world which if left un tackled leads to a variety of associated illnesses like Hypertension, Diabetes mellitus, Cardiovascular disorders, Cerebro vascular accidents etc. The common etiological factors which are implicated include sedentary life style, genetic fa ctors, dietary factors and endocrine factors, but the psychological factors are often overlooked which are the most important factor perpetuating binge eating behavour. The emotional instability, depression, stress, sexual abuse etc, often result in compulsive over eating leading to obesity. Thus the comprehensive management of obesity and the associated illnesses should include the proper tackling of these psychological components apart from other common thera pies. The present article critically analyses the role of these factors in the causation of obesity and its different management strategies which includes sattvavajaya as an Ayurvedic technique.