Browsing by Author "Poonam Dalal"

Now showing 1 - 2 of 2

Correction to: Impact of the indigenous rotavirus vaccine Rotavac in the Universal Immunization Program in India during 2016–2020 (Nature Medicine, (2025), 31, 11, (3871-3878), 10.1038/s41591-025-03998-9)
(Nature Research, 2025) Nayana P. Nair; Samarasimha Nusi Reddy; Sidhartha Giri; Tintu Varghese; Varunkumar Thiyagarajan; Jayaprakash Muliyil; Priya Hemavathy; Shainey Alokit Khakha; Rashmi Arora; Mohan Digambar Gupte; Jacqueline Elizabeth Tate; Umesh D. Parashar; Venkata Raghava Mohan; Gagandeep Kang; Mahima Mittal; Sunil Kumar Rao; Vineeta Gupta; Vipin M. Vashishtha; Sanjeev Kumar Verma; Kulandaivel Murugiah; Ramasubramaniam Pitchumani; Sridevi A. Naaraayan; Priyadarishini Dorairaj; Girish Kumar Chethrapilly Purusothaman; Senthilnathan Subramanian; Sumanth Amperayani; Sundaram Balasubramanian; Jayanta Kumar Goswami; Amrit Koirala; Shakti Lamichhane; Koshy C. George; Asolie Chase; Bhupesh Jain; Suresh C. Goyal; Dalpat Rajpurohit; Prabhu Prakash; Sunil Kothari; Vikash Katewa; Pramod Sharma; Shailja Vajpayee; Alok Kumar Goyal; Bharti Malhotra; R. K. Gupta; Prachi Chaudhary; Hemant Jain; Mannancheril Abraham Mathew; Asit Mansingh; Rashmi Patnaik; Samarendra Mahapatro; Subrat Kumar Majhi; Prasantajyoti Mohanty; Rajib Kumar Ray; Subrant Kumar Mohanty; Manas Kumar Nayak; Nirmal Kumar Mohakud; Mamata Devi Mohanty; J. Bikrant Kumar Prusty; Jasashree Choudhury; Mrutunjay Dash; Saroj Kumar Satpathy; Subal Kumar Pradhan; Jyoti Sharma; Sanjeev Chaudhary; Pancham Kumar; Shayam L. Kaushik; Rajesh Kumar; Bhavneet Bharti; Mini Pritam Singh; Muralidharan P. Jayashree; Akshay Kumar Saxena; Kushaljit Singh Sodhi; Arun Bansal; Ravi Prakash Kanojia; Adarsh Bansal; Madhu Gupta; Preeti Raikwar; Manoj Rawal; Anil Kumar Goel; Suraj Chawla; Poonam Dalal; Geeta Gathwala; Manohar Badur; Gorthi Rajendra Prasad; K. Kameswari; Padmalatha Pamu; Jeeru Bhaskara Reddy; J. Manikyamba; Krishna Babu Goru; G. S. Rama Prasad; G. V. Rama Devi; Suhasini Mekala; Sowmiya V. Senthamizh; Sunita Bidari
Correction to: Nature Medicinehttps://doi.org/10.1038/s41591-025-03998-9, published online 7 October 2025. In the version of the article initially published, Tintu Varghese (The Wellcome Trust Research Laboratory, Christian Medical College, Vellore, India) was missing from the author list and is now included, while the affiliation numbers shown for some Collaborators of the rotavirus vaccine effectiveness and impact assessment network members were incorrect. The author list and affiliations are now updated in the HTML and PDF versions of the article. © The Author(s) 2025.
Impact of the indigenous rotavirus vaccine Rotavac in the Universal Immunization Program in India during 2016–2020
(Nature Research, 2025) Nayana P. Nair; Samarasimha Nusi Reddy; Sidhartha Giri; Tintu Varghese; Varunkumar Thiyagarajan; Jayaprakash Muliyil; Priya Hemavathy; Shainey Alokit Khakha; Rashmi Arora; Mohan Digambar Gupte; Jacqueline Elizabeth Tate; Umesh D. Parashar; Venkata Raghava Mohan; Gagandeep Kang; Mahima Mittal; Sunil Kumar Rao; Vineeta Gupta; Vipin M. Vashishtha; Sanjeev Kumar Verma; Kulandaivel Murugiah; Ramasubramaniam Pitchumani; Sridevi A. Naaraayan; Priyadarishini Dorairaj; Girish Kumar Chethrapilly Purusothaman; Senthilnathan Subramanian; Sumanth Amperayani; Sundaram Balasubramanian; Jayanta Kumar Goswami; Amrit Koirala; Shakti Lamichhane; Koshy C. George; Asolie Chase; Bhupesh Jain; Suresh C. Goyal; Dalpat Rajpurohit; Prabhu Prakash; Sunil Kothari; Vikash Katewa; Pramod Sharma; Shailja Vajpayee; Alok Kumar Goyal; Bharti Malhotra; R. K. Gupta; Prachi Chaudhary; Hemant Jain; Mannancheril Abraham Mathew; Asit Mansingh; Rashmi Patnaik; Samarendra Mahapatro; Subrat Kumar Majhi; Prasantajyoti Mohanty; Rajib Kumar Ray; Subrant Kumar Mohanty; Manas Kumar Nayak; Nirmal Kumar Mohakud; Mamata Devi Mohanty; J. Bikrant Kumar Prusty; Jasashree Choudhury; Mrutunjay Dash; Saroj Kumar Satpathy; Subal Kumar Pradhan; Jyoti Sharma; Sanjeev Chaudhary; Pancham Kumar; Shayam L. Kaushik; Rajesh Kumar; Bhavneet Bharti; Mini Pritam Singh; Muralidharan P. Jayashree; Akshay Kumar Saxena; Kushaljit Singh Sodhi; Arun Bansal; Ravi Prakash Kanojia; Adarsh Bansal; Madhu Gupta; Preeti Raikwar; Manoj Rawal; Anil Kumar Goel; Suraj Chawla; Poonam Dalal; Geeta Gathwala; Manohar Badur; Gorthi Rajendra Prasad; K. Kameswari; Padmalatha Pamu; Jeeru Bhaskara Reddy; J. Manikyamba; Krishna Babu Goru; G. S. Rama Prasad; G. V. Rama Devi; Suhasini Mekala; Sowmiya V. Senthamizh; Sunita Bidari
In 2016, India introduced Rotavac (G9P[11]), an indigenous oral rotavirus vaccine administered at 6, 10 and 14 weeks of age through the Universal Immunization Program. Evaluating its effectiveness under routine programmatic conditions is critical, given the variable performance of rotavirus vaccines in low- and middle-income countries. Here we assessed Rotavac’s real-world effectiveness and impact across 31 hospitals in 9 states between 2016 and 2020 using a test-negative case–control design. Overall, 24,624 children were enrolled in surveillance (62% male and 38% female). Of 8,372 children aged 6–59 months eligible for effectiveness analysis (1,790 rotavirus-positive cases and 5,437 rotavirus-negative controls), 6,646 received 3 doses and 581 were unvaccinated. The adjusted vaccine effectiveness of 3 doses against severe rotavirus gastroenteritis was 54% (95% confidence interval (CI) 45% to 62%), with 1,574 vaccinated cases versus 5,072 vaccinated controls. Among children aged 6–23 months (1,486 vaccinated cases and 4,595 vaccinated controls), genotype-specific adjusted vaccine effectiveness was 51% (95% CI 36% to 62%) for G3P[8], 81% (95% CI 73% to 87%) for G1P[8] and 64% (95% CI 21% to 83%) for G1P[6]. Following vaccine introduction, rotavirus positivity among hospitalized children declined from 40% to 20%. These findings confirm that Rotavac provides substantial protection against severe rotavirus disease, including nonvaccine strains, and performs comparably to internationally licensed vaccines in similar settings. © The Author(s) 2025.