Browsing by Author "Praveen Kumar Gupta"

Now showing 1 - 4 of 4

Application of He's homotopy perturbation method for multi-dimensional fractional Helmholtz equation
(2012) Praveen Kumar Gupta; A. Yildirim; K.N. Rai
Purpose - This purpose of this paper is to find the approximate analytical solutions of a multidimensional partial differential equation such as Helmholtz equation with space fractional derivatives α, β, γ(1≤α ,β,γ<2). The fractional derivatives are described in the Caputo sense. Design/methodology/approach - By using initial values, the explicit solutions of the equation are solved with powerful mathematical tools such as He's homotopy perturbation method (HPM). Findings - This result reveals that the HPM demonstrates the effectiveness, validity, potentiality and reliability of the method in reality and gives the exact solution. Originality/value - The most important part of this method is to introduce a homotopy parameter (p), which takes values from [0,1]. When p =0, the equation usually reduces to a sufficiently initial form, which normally admits a rather simple solution. When p→1, the system goes through a sequence of deformations, the solution for each of which is close to that at the previous stage of deformation. Here, we also discuss the approximate analytical solution of multidimensional fractional Helmholtz equation. Copyright © 2012 Emerald Group Publishing Limited. All rights reserved.
Development of novel iron-regulated Pasteurella multocida B: 2 bacterin and refinement of vaccine quality in terms of minimum variation in particle size and distribution vis-a-vis critical level of iron in media
(Academic Press, 2020) Rajat Varshney; Ritu Varshney; Vinod Kumar Chaturvedi; Mayank Rawat; M. Saminathan; Vidya Singh; Rahul Singh; Monalisa Sahoo; Praveen Kumar Gupta
To enhance the qualitative bacterial biomass per unit of media and to overcome the limitations of the existing haemorrhagic septicaemia (HS) vaccines, a comprehensive study was undertaken encompassing the role of iron on the bacterial biomass of Pasteurella multocida B: 2 to vaccine development. Trypsin digested hydrochloric acid-treated sheep blood (THSB) as a novel iron rich supplement had been devised for the first time for augmenting the qualitative bacterial biomass per unit of media which was evident with growth kinetic study. The higher recovery of iron from THSB became evident via atomic absorbance spectrophotometry. The critical level of iron in the media as well as mode of iron supplementation showed a major impact on the outer membrane protein profile of P. multocida B:2 and variation in droplet size and particle-size distribution of formulated vaccine. Immune response study against iron-regulated bacterin adjuvanted with aluminum hydroxide gel in mouse model showed that 3% THSB supplementation of casein sucrose yeast (CSY) not only augmented the growth of P. multocida B:2 significantly but conferred highest pre-challenged ELISA IgG titer and protection against pasteurellosis. Thus, THSB supplementation of CSY can resolve existing up-scaling and immunogenic potential problems of HS vaccine production. © 2020
Pituitary Tuberculoma: An Uncommon Pathology
(Georg Thieme Verlag, 2021) Praveen Kumar Gupta; Sharad Pandey; Deepa Pandey
Pituitary tuberculomas are extremely rare with only few cases reported in the literature. Intracranial tuberculoma commonly presents with gradual onset of headache and visual disturbances with or without systemic symptoms. We reported such a case who presented with headache without any visual symptoms, occasional vomiting, and significant weight loss. Contrast magnetic resonance imaging scan was suggestive of pituitary macroadenoma. Transnasal transsphenoidal excision of the lesion (microscopic + endoscopic) was done. Histopathological examination revealed possibility of tuberculosis. Patient was put on standard antituberculosis treatment and discharged in a stable condition. © 2021 Georg Thieme. All rights reserved.
Uncommon presentation of choroid plexus papilloma in an infant
(Medknow Publications, 2016) Sharad Pandey; Vivek Sharma; Kulwant Singh; Amrita Ghosh; Praveen Kumar Gupta
Choroid plexus tumors are relatively rare primary brain tumors that arise from the epithelial differentiated tissue, majority being well-differentiated papillomas. In adults, fourth ventricle and in children, lateral ventricles are the most common site of these tumors. We reported a case of choroid plexus papilloma in the temporal horn of lateral ventricle in a female child who presented with the uncommon symptoms of sudden intraventricular hemorrhage and multiple episodes of seizure without symptoms of raised intracranial tension. © 2016 Journal of Pediatric Neurosciences.