Browsing by Author "Priya Chaudhary"

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Antipyretic Medicinal Plants, Phytocompounds, and Green Nanoparticles: An Updated Review
(Bentham Science Publishers, 2023) Priya Chaudhary; Rohit Sharma; Sonam Rawat; Pracheta Janmeda
Pyrexia itself is not a terminal condition. Basically, it occurs with mild to serious diseases affecting alarge population of the world. Other than a high body temperature, pyrexia is accompanied by several sickness behaviors, changes in physiological and metabolic characteristics of the body system, and alterations in the immune responses. Various allopathic drugs are available to treat pyrexia by targeting the symptom or the pathogen itself. Drug-resistance has made control and treatment of vectors more difficult. However, many marginal people are obligated to utilize locally available medicinal plants for the treatment of various diseases due to limited access to synthetic drugs. Developments in the field of nanotechnology and phytochemical research towards the discov-ery of new antimicrobial agents have also drawn the interest of researchers towards the synthesis of green nanoparticles from plant extracts due to their several benefits over the other methods. Thus, the present report discusses the use of ethnomedicinal plants, phytocompounds, and the application of green nanoparticles synthesized from plant extracts to treat pyrexia. © 2023 Bentham Science Publishers.
Etiology of lung carcinoma and treatment through medicinal plants, marine plants and green synthesized nanoparticles: A comprehensive review
(Elsevier Masson s.r.l., 2024) Priya Chaudhary; Pracheta Janmeda; Aaushi Pareek; Anil A. Chuturgoon; Rohit Sharma; Ashutosh Pareek
Lung cancer, a leading global cause of mortality, poses a significant public health challenge primarily linked to tobacco use. While tobacco contributes to over 90% of cases, factors like dietary choices and radiation exposure also play a role. Despite potential benefits from early detection, cancer patients face hurdles, including drug resistance, chemotherapy side effects, high treatment costs, and limited healthcare access. Traditional medicinal plant knowledge has recently unveiled diverse cancer chemopreventive agents from terrestrial and marine sources. These phytochemicals regulate intricate molecular processes, influencing the immune system, apoptosis, cell cycle, proliferation, carcinogen elimination, and antioxidant levels. In pursuing cutting-edge strategies to combat the diverse forms of cancer, technological advancements have spurred innovative approaches. Researchers have focused on the green synthesis of metallic nanoparticles using plant metabolites. This method offers distinct advantages over conventional physical and chemical synthesis techniques, such as cost-effectiveness, biocompatibility, and energy efficiency. Metallic nanoparticles, through various pathways such as the generation of reactive oxygen species, modulation of enzyme activity, DNA fragmentation, disruption of signaling pathways, perturbation of cell membranes, and interference with mitochondrial function resulting in DNA damage, cell cycle arrest, and apoptosis, exhibit significant potential for preventive applications. Thus, the amalgamation of phytocompounds and metallic nanoparticles holds promise as a novel approach to lung cancer therapy. However, further refinements and advancements are necessary to enhance the environmentally friendly process of metallic nanoparticle synthesis. © 2024 The Authors