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  1. Home
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Browsing by Author "R. Lakhan"

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    PublicationArticle
    CNS activity and synthesis of some 4 (3H)-quinazolinones
    (1990) R. Lakhan; R. Lakhan Singh
    [No abstract available]
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    Evaluation of p-nitrophenyl substituted semicarbazones for anticonvulsant properties
    (1999) S.N. Pandeya; I. Ponnilavarasan; A. Pandey; R. Lakhan; J.P. Stables
    A series of p-nitrophenyl substituted semicarbazones has been synthesised and their anticonvulsant activity was screened against MES, scPTZ and scSTY. 4(4'-Nitrophenyl)-o-nitrobenzaldehyde semicarbazone has been found to be the most active in all these tests. The studies revealed that a primary amino function is not essential for anticonvulsant activity in the semicarbazone series of compounds. Presumably these compounds could further act on glycine receptors.
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    Local anaesthetics. IV. Synthesis and activity of 2-(N-substituted or N,N-disubstituted aminoacetamido)-4- or -4,5-substituted thiazoles
    (1986) R. Lakhan; B.J. Rai
    [No abstract available]
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    Local anaesthetics. Part-III: Synthesis of 2-(N-substituted or N,N-disubstituted aminoacetamido)-4 aryl thiazoles
    (1984) R. Lakhan; O.P. Singh
    [No abstract available]
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    Local anesthetics. II. Synthesis of 2-(N,N-disubstituted aminoacetamido)-4-p-fluorophenyl and -m-methoxyphenyl thiazoles
    (1982) P.N. Bhargava; R. Lakhan; R. Tripathi
    [No abstract available]
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    Potential CNS active agents. II Studies of 4(3H)-quinazolinones
    (1988) R. Lakhan; R.L. Singh
    [No abstract available]
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    Studies on 4(3H)-quinazolinone derivatives as antimalarials
    (1987) R. Lakhan; O.P. Singh; R.L. Singh
    [No abstract available]
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    PublicationNote
    Synthesis of benzothiazolylguanidines as antituberculars and antibacterials
    (1968) N.P. Bhargava; R. Lakhan
    The synthesis of twenty three new N-p-tolyl-N′-2-(substituted)benzothiazolyl-N″-alkyl-guanidines has been reported. Several of these including some N-p-tolyl-N′-2-(substitued)- benzothiazolylguanidines* have been evaluated for their antitubercular activity against M. tuberculosis (H 37 Rv) and also for their antibacterial activity. Among these N-p-tolyl-N′-2-(6-methoxy)benzothiazolylguanidine and N-p-tolyl-N′2-(6-methyUbenzothiazolyl-N″-methyl-guanidine are the most active as antituberculars but all the tested compounds are inactive as antibacterials. © 1968 Taylor and Francis Group LLC.
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    Synthesis of benzothiazolylguanidines as antituberculars and antibacterials
    (1968) N.P. Bhargava; R. Lakhan
    The synthesis of twenty three new N-p-tolyl-N′-2-(substituted)benzothiazolyl-N″-alkyl-guanidines has been reported. Several of these including some N p-tolyl-N′-2-(substitued)-benzothiazolylguanidines* have been evaluated for their antitubercular activity against M. tuberculosis (H 37 Rv) and also for their antibacterial activity. Among these N-p-tolyl-N'-2-(6-methoxy)benzothiazolylguanidine and N p-tolyl-N'-2-(6-methyl)benzothiazolyl-N"-methyl-guanidine are the most active as antituberculars but all the tested compounds are inactive as antibacterials. © 1968, Japan Society for Bioscience, Biotechnology, and Agrochemistry. All rights reserved.
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