Browsing by Author "R.K. SINGH"

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Breeding for increased nitrogen fixing ability among wild and cultivated species of chickpea
(1990) H.K. JAISWAL; R.K. SINGH
Two chickpea species, one wild (Cicer reticulatum JM2106) and one cultivated (C. arietinum ICC8923) were selected as the parents for this study. C. reticulatum showed high nodule number, nodule dry weight and nitrogen content/plant as compared to C. arietinum. In lines derived from the crosses H208 × (ICC8923 × JM2106) and BG274 × (ICC8923 × JM2106), increase in nodule dry weight, nitrogen content/plant, plant dry weight and grain yield was observed over the parent ICC8923. Similarly F6 lines also showed improvement in these traits over the cultivated parent. It is concluded that the increase in grain yield and dry matter is the result of improvement in nitrogen utilisation together with an increase in the available fixed nitrogen. Copyright © 1990, Wiley Blackwell. All rights reserved
Effect of interferon‐gamma priming on the activation of murine peritoneal macrophages to tumouricidal state by cisplatin, IL‐1, and tumour necrosis factor (TNF): production of IL‐1 and TNF
(1992) A. SODHI; R.K. SINGH; S.M. SINGH
The effect of interferon‐gamma (IFN‐γ) priming of murine peritoneal macrophages on the activation to tumouricidal state by cisplatin. lipopolysaccharide (LPS)‐IL‐1 and TNF was investigated. Cisplatin‐, LPS‐, IL‐1‐ or TNF‐treated IFN‐γ‐primed macrophages showed significantly enhanced tumouricidal activity and binding to tumour cells, compared with unprimed treated or untreated macrophages. Macrophages treated with cisplatin, LPS, IL‐1 and TNF produced released and membrane‐associated IL‐1 and TNF activity which was significantly enhanced after priming with IFN‐γ. These observations suggest the use of IFN‐γ along with these biological response modifiers in designing immunotherapeutic protocols for treatment of malignancy. Copyright © 1992, Wiley Blackwell. All rights reserved