Browsing by Author "Rashmi Gupta"

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A comparative analysis of phytochemicals versus synthetic drugs/nanomedicines in the treatment of uterine fibroid: a systematic review
(Korean Society of Environmental Risk Assessment and Health Science, 2024) Sonal Upadhyay; Vivek Pandey; Anima Tripathi; Alakh N. Sahu; Anjali Rani; Amita Diwakar; Lavina Chaubey; Rashmi Gupta; Pawan K. Dubey
Most women experience uterine fibroids (UFs), a common benign gynecological tumor, at some point in their reproductive age. There are several pharmacological treatments available to shrink fibroids and lessen the UF symptoms. These medications cost a lot of money, though, and frequently have serious side effects. Therefore, due to their low cost, comparable and powerful therapeutic efficiency and lower side effects, phytochemical-based medications are gaining popularity in these days. This review's goal is to provide a summary of the knowledge that is currently unavailable regarding the mechanisms of the action of various phytochemical-based medications with anti-uterine fibroid efficacy. The present results showed that dietary phytocompounds (dehydroxyelephantopin, butein, capsaicin, fisetin, kaempferol, resveratrol, silibinin and curcumin) could probably be effective as therapeutic compounds for uterine leiomyoma. These phytochemicals indicated their capability to regulate main fibroid promoting and initiating events for instance, proliferation, inflammation, angiogenesis and fibrosis in various experimental setups through modulating various signaling pathways, such as Smad 2/3, PI3K/AKT/mTOR, ERK 1/2 and β-catenin indicating that they could serve as targets for prevention and/or treatment of UFs. This review provides key molecular insights for the development of phytochemical-based novel personalized therapy for non-surgical management of UFs which may help to avoid hysterectomy. © The Author(s), under exclusive licence to Korean Society of Environmental Risk Assessment and Health Science 2023.
A review of Antarctic ice sheet fluctuations records during Cenozoic and its cause and effect relation with the climatic conditions
(Elsevier B.V., 2021) Mayuri Pandey; Naresh Chandra Pant; Devsamridhi Arora; Rashmi Gupta
Antarctic cryosphere has significant impact on the global climate system by influencing the ocean currents, the atmosphere, and the sea level for long term durations. Antarctic Ice Sheet (AIS) has evolved from temporary to permanent ice sheet during Oligocene (~32 Ma). Throughout its evolution, it witnessed severe climatic conditions leading to several phases of retreat and advancements. Major climatic events were directly associated with the evolution of AIS. Paleocene Eocene Thermal Maximum (PETM), Early Eocene Climatic Optimum (EECO, ~44.9 Ma), Eocene Oligocene Boundary (Oi1 event, ~34 Ma), Oligocene-Miocene Boundary (Mi1 event ~25Ma), Mid Miocene Climatic Optimum (MMCO; ~15Ma), Miocene-Pliocene Boundary (~3Ma) and Mid-late Pleistocene Transition (MPT, after ~1.25 Ma) are the major reported global climatic events. This work summarises these events and critically reviews the role of various factors in the advancement and retreat of AIS and its coupled response to the global climate change including future global challenges. Existing knowledge gaps and challenges are outlined for each of the climatic events and priorities for future research are suggested. © 2021
Analgesic and Anti-inflammatory Potential of Ricinus communis Linn.: Evidence from Pharmacology to Clinical Studies
(Springer Science and Business Media Deutschland GmbH, 2024) Rashmi Gupta; Anand K. Chaudhary; Rohit Sharma
Purpose of Review: Ricinus communis Linn. is a rapidly growing perennial herb (aka Eranda or castor plant) that has long been used to cure a range of ailments in traditional medicine. An extensive search on its ethnomedicinal, phytochemistry, and pharmacotherapeutic potential is completed by meticulously examining information retrieved from Web of Science, PubMed, SciFinder, Google Scholar, Embase, and Infrastructure databases. Recent Findings: The plant has yielded beneficial chemical compounds such as alkaloids, flavonoids, coumarins, terpenoids, sterols, and fatty acids. Several reports are available on the anti-inflammatory, antinociceptive, antiasthmatic, antifertility, antihistaminic, hepatoprotective, antimicrobial, free radical scavenging activities, antioxidant, and various other biological roles of the crude herb and its metabolites. This review comprehensively discusses the biopotential of R. communis in pain and inflammation, as evident from in vitro, in vivo, and clinical data, as well as safety and toxicity concerns, various market formulations, and drug-drug interactions. R. communis shows potent anti-inflammatory and analgesic activity possibly by NF-kB, Nrf2, RAF/ERK, Fas receptor, and caspase-mediate apoptosis and Wnt signalling pathways. Summary: R. communis is widely distributed globally and is rich in bioactive phytoconstituents with multifaceted therapeutic roles. It modulates numerous inflammatory and biochemical markers and highlights its potential in the management of nociception and inflammation. These findings could pave the way for the identification and developing more effective strategies to combat nociception and inflammatory disorders. Graphical Abstract: [Figure not available: see fulltext.] © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Chemical modification of carboxylated MWCNTs for enhanced electrical conducting and magnetic properties
(Elsevier Ltd, 2020) Rashmi Gupta; Bachcha Singh
An electrical conducting and magnetic nanomaterial, [Ni(II)Hyd]-MWCNTs was synthesized via chemical modification of carboxylated MWCNTs (A-MWCNTs). The synthesized material has been studied by FTIR, UV–Visible, XPS, Raman, TGA, powder XRD, TEM and EDAX analysis. Double probe DC conductivity suggested enhanced electrical conductivity of [Ni(II)Hyd]-MWCNTs compared to A-MWCNTs. (RsQ(RctO)) is found to be best fit Randle's equivalent circuit. The positive slope obtained from Mott-Schottky plot suggested n- type semiconducting behavior of materials. The positive shift in flat-band potential for [Ni(II)Hyd]-MWCNTs is the signature of its more conducting nature than that of A-MWCNTs. The better conductivity of [Ni(II)Hyd]-MWCNTs is also confirmed by optical and electrochemical band gap studies. The field and temperature dependent magnetization revealed intrinsic ferromagnetism in [Ni(II)Hyd]-MWCNTs with enhanced saturation magnetization, remanent magnetization and coercivity values compared to A-MWCNTs. Hence, high electrical conductivity and magnetic properties prompt the [Ni(II)Hyd]-MWCNTs for applicability in spin-based electronic devices and in other application such as EMI shielding, metamaterials, drug delivery, anticorrosion, etc. © 2020 Elsevier B.V.
Design and development of a multiwalled carbon nanotubes-based copper (II) Schiff base complex for the facile non-enzymatic electrochemical sensing of glucose
(Springer, 2023) Rashmi Gupta; Mamta Yadav; Smita Singh; Vellaichamy Ganesan; Bachcha Singh
A new bifunctional nanomaterial, [SBCu(II)Hyd]-MWCNTs, exhibiting exotic electrical and magnetic properties has been synthesized via chemical modification of MWCNT-COOH. Double probe DC electrical conductivity, CV and EIS studies show better conductivity of the material than that of MWCNT-COOH. With higher saturation and remanent magnetization, as well as coercivity, [SBCu(II)Hyd]-MWCNTs showed better ferromagnetic characteristics. Mott–Schottky electrochemical analysis was carried out to explore capacitive and dielectric properties. The enhancement in electrical conductivity of [SBCu(II)Hyd]-MWCNTs is also confirmed by optical and electrochemical band gaps studies. Subsequently, this material has been utilized to fabricate an electrochemical sensor by coating it over glassy carbon electrode for the determination of glucose. The corresponding sensitivity and limit of detection values are calculated to be 1.1 µA µM−1 cm−2 and 0.09 µM, respectively. Graphical Abstract: [Figure not available: see fulltext.] © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Effect of Ni addition on PNZT tungsten bronze structure
(Springer New York LLC, 2018) Rashmi Gupta; Deepa Singh; Ranjan K. Singh; K.K. Bamzai
Lead niobate zirconate titanate (PNZT) with general formula 0.5PbNb2O6–0.5Pb(ZrxTi1-x)O3 (where x = 0.15, 0.25, 0.35) and lead nickel niobate zirconate titanate (PNNZT) with general formula Pb(NixNb0.5-xZr0.25Ti0.25)O3 (where x = 0.167, 0.250, 0.333) have been prepared by conventional solid state reaction. The phase formation has been studied by X – ray diffraction analysis. Raman investigations have been carried out in the 200–1000 cm−1 wave number range. The structural changes observed in the X – ray diffraction pattern has been further confirmed by Raman analysis. The major changes in the E(1TO), A1(1TO) and E + B1 phonon modes suggest the structural change from cubic to rhombohedral with increase in Ni concentration in PNNZT. The optical band gap has been calculated from UV – Vis absorption spectra. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Enhancement of electrical conductivity and magnetic properties of bimetallic Schiff base complex on grafting to MWCNTs
(Springer New York LLC, 2019) Rashmi Gupta; Bachcha Singh
In present work, we report a newly synthesized nano-inorganic hybrid magnetic material, [SBCu(II)Gd(III)]@MWCNT-COOH which is obtained by anchoring of a copper(II)–gadolinium(III) heteronuclear bimetallic complex, [triaqua(2-hydroxy-1,3-bis(3-methoxysalicylaldiminato)Cu(II)Gd(III)dinitrato)]nitrate monohydrate, [SBCu(II)Gd(III)] to carboxylated multiwalled carbon nanotubes (MWCNT-COOH) through a chemical method. MWCNT-COOH have been loaded with a number of [SBCu(II)Gd(III)] molecules on their surfaces, which generated multinuclear metal centers. [SBCu(II)Gd(III)]@MWCNT-COOH was characterized by FT-IR, UV–Vis, TGA, powder XRD, Raman spectroscopy, TEM, HRSEM, EDAX and elemental mapping. The DC electrical conductivity of materials was evaluated using two probe method suggesting that [SBCu(II)Gd(III)]@MWCNT-COOH is more conducting than [SBCu(II)Gd(III)]. The increased conductivity of [SBCu(II)Gd(III)]@MWCNT-COOH is confirmed by CV and EIS study. The capacitive and dielectric properties of the materials were investigated by Mott–Schottky electrochemical analysis. The positive value of slope signified n-type semiconducting nature of materials. The lower slope for [SBCu(II)Gd(III)] signified the strong dielectric behavior of the material. The positive shift in flat-band potential of [SBCu(II)Gd(III)]@MWCNT-COOH compared to [SBCu(II)Gd(III)] indicated its more conducting nature. Further small optical band gap obtained for [SBCu(II)Gd(III)]@MWCNT-COOH than [SBCu(II)Gd(III)] by UV–Vis studies suggested better conductivity of nano-inorganic hybrid material. Field dependent magnetization revealed enhanced saturation magnetization, remanent magnetization and coercivity of [SBCu(II)Gd(III)]@MWCNT-COOH due to generation of multinuclear metal centers on carboxylated MWCNTs. The temperature dependent magnetization measurement exhibited overlapping of field cooled and zero field cooled curves in entire temperature range (2–300 K), suggests intrinsic ferromagnetism in [SBCu(II)Gd(III)]@MWCNT-COOH. Hence, trend in variation of magnetization with magnetic field and temperature opens its utility in spin-based electronic devices. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Evidence of Paleoproterozoic metamorphism in Vestfold Hills, East Antarctica: Insights from phase equilibria modelling and monazite CHIME dating
(Elsevier B.V., 2023) Aditya Naik; Devsamridhi Arora; Mayuri Pandey; Naresh Chandra Pant; Rashmi Gupta
The Vestfold Hills sector on the coastal fringe of the Princess Elizabeth Land forms part of an Archean to Paleoproterozoic aged cratonic nucleus of the East Antarctic Shield. A charnockite-granite association from the Mossel Gneiss Group in the northern region of the Vestfold Hills is investigated in this work to characterise the metamorphic-magmatic evolution of the area. Conventional thermometry and phase equilibria modelling indicate that the charnockite formed as a result of ultra-high temperature metamorphism at low-intermediate pressure (∼4 kbar). Phase equilibria modelling, reveals that the melt-integrated charnockite composition is a restitic product of a protolith of quartz diorite composition which underwent isobaric heating (peak temperature up to 960 °C) at 4 kbar pressure followed by anatexis. The anatexis of the quartz diorite protolith also resulted in the formation of the associated granitic melt. U–Th-PbTotal ages obtained from monazites of the granite integrated with CHIME ages extracted using the isochron method indicate an emplacement age of ∼2200 Ma and two younger events are recorded at ∼2000 Ma and ∼1700 Ma. The younger ages are ascribed to the resetting during the emplacement of younger basalt dykes that cross cut the charnockite-granite sequence. Vestfold Hills’ geological correlations with Indian and Australian cratons are discussed considering this new data. © 2023 Elsevier B.V. and NIPR
Evincing the presence of a trans-Gondwanian mobile belt in the interior of the Princess Elizabeth Land, East Antarctica: insights from offshore detrital sediments, rock fragments, and monazite geochronology
(John Wiley and Sons Ltd, 2022) Rashmi Gupta; Mayuri Pandey; Devsamridhi Arora; Naresh Chandra Pant; N. V. Chalapathi Rao
East Gondwana was assembled through the stitching of the Indo-Antarctica and Australo-Antarctica domains which also represents the key Gondwana-forming regions in present-day East Antarctica. However, the Indo-Antarctica and Australo-Antarctica boundaries remain speculative and contentious, as the thick Antarctic Ice sheet precludes direct geological characterization of these terranes. In addition, the exact role of the Gamburtsev Subglacial Mountains, present in the interior of Princess Elizabeth Land (PEL), during the amalgamation of Gondwana, has not been well understood. We present new mineralogical data of offshore sediments from Prydz Bay to infer the geology of the interior of the PEL terrain, East Antarctica. Coast marginal outcrops dominantly expose igneous and granulite facies metamorphic rocks. Heavy minerals characterization of the rock fragments followed by consideration of the outcrop geology indicate a possible contribution of sediments from the far interior of PEL terrain. Total U–Pb chemical geochronology of detrital monazites dominantly shows a bimodal age distribution ascribable to Stenian to Tonian (~1,100 Ma, 900 Ma) event ages and a younger Pan-African event (~500 Ma). Besides these, Tonian-Cryogenian (~700 Ma) ages from texturally constrained monazites of a low-grade schist rock fragment is reported for the first time from this sector. Consideration of glacial flow directions and the nature of rock fragments indicate their sourcing from the distal hinterland. The possible provenance is inferred to be from the Gamburtsev Subglacial Mountains. © 2022 John Wiley & Sons Ltd.
Homocysteine and vitamin B12: Other causes of neural tube defects in Eastern Uttar Pradesh and Western Bihar population
(Wolters Kluwer Medknow Publications, 2018) Rashmi Gupta; Preeti Kumari; Sharad Pandey; Deepika Joshi; Shiv Sharma; Sunil Rai; Royana Singh
Background: Neural tube defects (NTDs) are congenital malformations with an incidence of 1-10/1000 live births. Homocysteine and vitamin B12 metabolism have been shown to be associated with NTDs. Aim: To investigate the status of maternal and neonate's folic acid, homocysteine, and vitamin B12 levels and their association with the risk of development of NTDs in the population of Eastern Uttar Pradeshand Western Bihar, India. Materials and Methods: This study is a cross-sectional, retrospective study where 96 mothers who either had a first NTD child or had a history of NTD child in the family and 126 neonates with spina bifida were recruited during the period 2012-2015. Eighty-four control mothers whose previous and current pregnancies were normal, and 87 control neonates who had no defects and were within the same age range as the NTD affected neonates, recruited from the department of pediatric surgery, were enrolled in the study. Plasma concentrations of folic acid, vitamin B12, and homocysteine were compared between cases and controls. Results: The folic acid level in the mothers and neonates was within the normal limit. A significant increase in the level of homocysteine in mothers with affected pregnancy and in neonate cases in comparison to control mothers was obseved. Further, a significant decrease in the level of vitamin B12 in mothers with NTD neonates and in the affected neonates was noted. A negative correlation was found between homocysteine and vitamin B12 levels in case and control mothers. Conclusion: A correlation of an increase in serum homocysteine with a decrease in vitamin B12 was seen in mothers of neonates with NTD. A similar observation as made in the neonates with NTDs. It may be suggested that maternal decrease in vitamin B12, in mothers who have normal folic acid may be associated with NTD in their children. © 2018 Neurology India, Neurological Society of India | Published by Wolters Kluwer - Medknow.
Neoproterozoic crustal evolution of Indo-Australo-Antarctic Suture domain and Gamburtsev Subglacial Mountains, East Antarctica: Insights from offshore sediments
(Elsevier Inc., 2024) Rashmi Gupta; Mayuri Pandey; Devsamridhi Arora; Akash K. Pandey; Naresh C. Pant; K. Batuk Joshi; Pankaj Kumar; M. Satyanarayanan; Atul Singh
Princess Elizabeth Land (PEL) preserves an intricate amalgamation of complexly intersecting orogenic belts of the Gondwanian age cross cut by the ramified East Antarctic Rift system. Indo-Australo-Antarctic Suture (IAAS) is an extensive orogenic zone connecting the Africo-Antarctic domain of Dronning Maud Land to the Australo-Antarctic domain of Wilkes Land region through the Indo-Antarctic domain of Princess Elizabeth Land, touching the northern boundary of the Gamburtsev Subglacial Mountains (GSMs). The GSMs and IAAS, located in the interior of PEL, are completely hidden within the ice sheet. The connection between the IAAS and concealed GSMs remains ambiguous due to insufficient geological evidence. Marine sediments from Prydz Bay offer clues to explore this segment of PEL. In this work, sediments from Ocean Drilling Program (ODP) sites: 740, 742, and 739, representing proximal to relatively distal sites, respectively, were subjected to geochemical and zircon isotopic analyses to understand the crustal evolution of PEL, IAAS, and GSM. The sediment geochemistry indicates that sediments from site 740, being proximal, are immature, less recycled, and more chemically weathered as compared to sites 742 and 739. Discriminant plots of major and trace elements provide active and passive continental margin signatures. Site 739 and 742 sediments display the rift setting signatures while sediments of site 740 depict signatures of collisional setting supporting the presence of an orogenic belt in the interior of PEL. Zircons from the proximal sites display age ranges from Paleoproterozoic to Pan-African. Zircons from the distal site predominantly show ages ∼650 Ma, hinting at the possibility of a Tonian-Cryogenian event in the hinterland of the PEL sector, possibly in the GSMs. Our results provide a better understanding of the Neoproterozoic crustal evolution of the IAAS domain of the PEL sector. © 2024 International Association for Gondwana Research
PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
(Oxford University Press, 2017) Massimo Zollo; Mustafa Ahmed; Veronica Ferrucci; Vincenzo Salpietro; Fatemeh Asadzadeh; Marianeve Carotenuto; Reza Maroofian; Ahmed Al-Amri; Royana Singh; Iolanda Scognamiglio; Majid Mojarrad; Luca Musella; Angela Duilio; Angela Di Somma; Ender Karaca; Anna Rajab; Aisha Al-Khayat; Tribhuvan Mohan Mohapatra; Atieh Eslahi; Farah Ashrafzadeh; Lettie E. Rawlins; Rajniti Prasad; Rashmi Gupta; Preeti Kumari; Mona Srivastava; Flora Cozzolino; Sunil Kumar Rai; Maria Monti; Gaurav V. Harlalka; Michael A. Simpson; Philip Rich; Fatema Al-Salmi; Michael A. Patton; Barry A. Chioza; Stephanie Efthymiou; Francesca Granata; Gabriella Di Rosa; Sarah Wiethoff; Eugenia Borgione; Carmela Scuderi; Kshitij Mankad; Michael G. Hanna; Piero Pucci; Henry Houlden; James R. Lupski; Andrew H. Crosby; Emma L. Baple
PRUNE is a member of the DHH (Asp-His-His) phosphoesterase protein superfamily of molecules important for cell motility, and implicated in cancer progression. Here we investigated multiple families from Oman, India, Iran and Italy with individuals affected by a new autosomal recessive neurodevelopmental and degenerative disorder in which the cardinal features include primary microcephaly and profound global developmental delay. Our genetic studies identified biallelic mutations of PRUNE1 as responsible. Our functional assays of disease-associated variant alleles revealed impaired microtubule polymerization, as well as cell migration and proliferation properties, of mutant PRUNE. Additionally, our studies also highlight a potential new role for PRUNE during microtubule polymerization, which is essential for the cytoskeletal rearrangements that occur during cellular division and proliferation. Together these studies define PRUNE as a molecule fundamental for normal human cortical development and define cellular and clinical consequences associated with PRUNE mutation. © The Author (2017).
Role of tannic acid in desiging of electrically active and magnetic gold nanoparticles and enhanced photovoltaic performance of gold@titania photoanode in DSSC
(Elsevier Ltd, 2022) Rashmi Gupta; Shalini Singh; Pankaj Srivastava; Bachcha Singh
We describe here in significance of tannic acid in obtaining size dependent electrochemically active and magnetic gold nanoparticles (GNPs). In this account, two types of GNPs (SCGNPs and SC-TAGNPs) were synthesized by using sodium citrate and sodium citrate-tannic acid as reducing agents, respectively. Highly monodispersed, uniformly distributed and small size GNPs were produced when tannic acid was used together with sodium citrate. SC-TAGNPs exhibited room temperature ferromagnetism while SCGNPs revealed diamagnetism. With higher anodic peak current and lower charge transfer resistance, the SC-TAGNPs exhibited better conductivity and electron transfer ability than SCGNPs. Mott-Schottky analysis revealed n-type semiconducting behavior of GC/SCGNPs & GC/SC-TAGNPs and showed positive shift in flat-band potential of GC/SC-TAGNPs compared to GC/SCGNPs suggesting better conductivity of SC-TAGNPs. Subsequently, SCGNPs and SC-TAGNPs were added to TiO2 nanoparticles to fabricate modified titania photoanodes (SCGNPs@TiO2 and SC-TAGNPs@TiO2) for dye-sensitized solar cells (DSSCs) application. With the use of TiO2, SCGNPs@TiO2 and SC-TAGNPs@TiO2 photoanodes, the short-circuit current density (JSC) was observed to be 2.18, 4.50 and 6.68 mA/cm2, while energy conversion efficiency (η) was found to be 0.75, 1.74 and 2.50%, respectively. The TiO2 photoanode employing SC-TAGNPs exhibited remarkably increased JSC and η by ∼48 and ∼44%, respectively, then SCGNPs modified photoanode. © 2021 Elsevier B.V.
Shatavarin-IV rescues the Di (2-ethylhexyl) phthalate (DEHP) induced oxidative stress in rat granulosa cells in vitro
(Elsevier Inc., 2024) Vivek Pandey; Alka Sharma; Sonal Tiwari; Yashvant Patel; Jayhind Kumar Chauhan; Safiya Ayesha; Alakh N. Sahu; Rashmi Gupta; Anima Tripathi; Pawan K. Dubey
Studies provide notable evidence that oxidative stress (OS) mediated reactive oxygen species (ROS) disturb reproductive health. We have shown in our previous publication that exposure of Di-(2-ethylhexyl) phthalate (DEHP), induces OS mediated ROS generation which inhibits steroid synthesis. In the present study, we demonstrated the ameliorative/protective effects of one of the steroidal saponins, i.e., Shatavarin-IV, isolated from the roots of Asparagus racemosus against DEHP induced OS in rat granulosa cells. Granulosa cells were exposed with DEHP alone (400 μM), Shatavarin-IV alone (8 μg/ml), and a combination of DEHP + Shatavarin-IV (400 μM + 8 μg/ml) in vitro for 24 hrs. Intracellular ROS, OS/hypoxia, mitochondrial membrane potential, steroid-responsive genes expression were analyzed. The results revealed that the effective dose of DEHP (400 µg) significantly increased OS compared to the control by increasing ROS levels, mitochondrial membrane potential, and β-galactosidase activity with a higher level of apoptotic genes (Bax, Caspase-3) expression at mRNA level. Further, DEHP significantly (p < 0.05) reduced mRNA expression of steroidogenic responsive genes (StAR, CYP17A1, and CYP19A1) in granulosa cells treated with above combination compared to control. Interestingly, co-treatment of DEHP + Shatavarin-IV significantly suppressed the DEHP induced OS, ROS, β-galactosidase levels and enhanced steroidogeneic and apoptotic gene expression activities, which suggests that Shatavarin-IV rescued DEHP-induced changes that may useful for the prevention of DEHP- induced reproductive toxicity. © 2024 Elsevier Inc.
Unravelling the complex sub-ice geology of the Wilkes Subglacial Basin region of East Antarctica from marine sediment provenance analyses
(Cambridge University Press, 2023) Mayuri Pandey; Naresh Chandra Pant; Devsamridhi Arora; Fausto Ferraccioli; Rashmi Gupta; Sonalika Joshi
Deciphering the sub-ice geology in the Wilkes Subglacial Basin region is important for understanding solid earth-ice sheet evolution and for assessing geological ties between East Antarctica and formerly contiguous Australia. We analyse marine sediment samples derived from drill site U1359 of Integrated Oceanic Drilling Program Expedition 318. Our study reports for the first time that the inland sediment source area comprises a complex mafic igneous terrain and a metamorphosed Precambrian subglacial basement. Pyroxene geochemical analyses confirm the presence of tholeiitic to calc-alkaline basalts. The high-grade part of the subglacial terrain contains upper amphibolite to granulite facies rocks that are comparable to Archaean to Palaeoproterozoic rocks exposed in the Terre Adélie Craton and the formerly adjacent Gawler Craton in Australia. Chemical Th-U-total Pb isochron method (CHIME) ages extracted from a subhedral monazite grain associated with the low-grade biotite-muscovite schist rock fragment provide a unimodal age of 799 ± 13 Ma. Rare occurrences of 800 Ma age in the Terre Adélie Craton and/or George V Coast provide evidence for the presence of at least one late Neoproterozoic magmato-metamorphic event in the interior of Wilkes Land. The affinity of the unexposed geological domains of Wilkes Land, East Antarctica, with their Australian counterparts is discussed in the context of the Rodinia supercontinent. Copyright © The Author(s), 2023. Published by Cambridge University Press on behalf of Antarctic Science Ltd.