Browsing by Author "Ritika Khanna"

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Ulcers in Hypercoagulable States
(Springer Nature, 2023) Ritika Khanna; Rahul Khanna
Cutaneous ulcers in hypercoagulable states or thrombophilia are a manifestation of underlying localized ischemia or tissue hypoxia. They can occur in any of the numerous conditions which affect components of Virchow’s triad, viz. hyperviscosity of blood, endothelial injury, and hypercoagulability producing diseases. The commonly encountered thrombophilia-associated ulcers are manifestations of APLA syndrome, cold-associated disease, sickle cell disease, warfarin- and heparin-associated ulcers, hydroxyurea-associated ulcers, cholesterol emboli-associated ulcers, calciphylaxis, and Martorell’s hypertensive ischemic ulcers. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023.