Browsing by Author "S. Dube"

Now showing 1 - 4 of 4

Adverse effects of oral amiodarone therapy.
(1992) P.R. Sinha; S. Dube; Sujata; P.R. Gupta; P. Avasthey; P.N. Somani
Oral amiodarone was administered to 38 patients (25 males, 13 females) with mean age of 43.6 years. Ventricular and supraventricular arrhythmias were present in 30 and 8 patients respectively. Amiodarone was given as 400-1200 mg/day for 1-2 weeks as loading dose and then it was maintained as 100-600 mg/day. The mean duration of therapy was 12.4 months. Adverse effects were noted in 21 (55.3%) cases. The commonest adverse effects observed were asymptomatic corneal microdeposits followed by gastrointestinal, cardiac, neurological and cutaneous disturbances. The drug was withdrawn in 2 (5.3%) patients because of nausea and vomiting. One patient died of pulmonary infiltrations. It is concluded that adverse effects are common with amiodarone but are tolerated well, making this drug an excellent choice for treatment of cardiac arrhythmias.
Cytohormonal assessment of ovarian function following tubal ligation
(John Wiley and Sons Ltd, 1979) S. Khanna; L. Parthasaruthi; S. Dube; S. Gupta
One hundred fifty postligation and 54 random cases matched for age and parity were studied. Vaginal cytologic samples and endometrial histologic samples were used for cytohormonal assessment of ovarian function. There was no indication of ovarian insufficiency following tubal ligament. The menstrual cycles were ovulatory. Menstrual disturbances were seen in 40.6% of the cases following tubal ligation. Cytohormonal comparison of these cases with that of dysfunctional uterine bleeding cases (who did not undergo tubal ligation) showed either similar or high maturation value. This may be due either to psychological stimulation or to low grade infection following tubal ligation. There was complete cytomorphologic correlation.
Flagyl therapy in prophylaxis and treatment of anaerobic infections in gynaecological surgery
(1979) S. Dube; B.K. Kapoor; K.N. Srivastava
[No abstract available]
Vaccination saves lives: a real-time study of patients with chronic diseases and severe COVID-19 infection
(Oxford University Press, 2023) A. Mukherjee; G. Kumar; A. Turuk; A. Bhalla; T.C. Bingi; P. Bhardwaj; T.D. Baruah; S. Mukherjee; A. Talukdar; Y. Ray; M. John; J.R. Khambholja; A.H. Patel; S. Bhuniya; R. Joshi; G.R. Menon; D. Sahu; V.V. Rao; B. Bhargava; S. Panda; P. Mishra; Y. Panchal; L.K. Sharma; A. Agarwal; G.D. Puri; V. Suri; K. Singla; R. Mesipogu; V.S. Aedula; M.A. Mohiuddin; D. Kumar; S. Saurabh; S. Misra; P.K. Kannauje; A. Kumar; A. Shukla; A. Pal; S. Chakraborty; M. Dutta; T. Mondal; S. Chakravorty; B. Bhattacharjee; S.R. Paul; D. Majumder; S. Chatterjee; A. Abraham; D. Varghese; M. Thomas; N. Shah; M. Patel; S. Madan; A. Desai; M.L. Kala Yadhav; R. Madhumathi; G.S. Chetna; U.K. Ojha; R.R. Jha; A. Kumar; A. Pathak; A. Sharma; M. Purohit; L. Sarangi; M. Rath; A.D. Shah; L. Kumar; P. Patel; N. Dulhani; S. Dube; J. Shrivastava; A. Mittal; L. Patnaik; J.P. Sahoo; S. Sharma; V.K. Katyal; A. Katyal; N. Yadav; R. Upadhyay; S. Srivastava; A. Srivastava; N.N. Suthar; N.M. Shah; K. Rajvansh; H. Purohit; P.R. Mohapatra; M.K. Panigrahi; S. Saigal; A. Khurana; M. Panchal; M. Anderpa; D. Patel; V. Salgar; S. Algur; R. Choudhury; M. Rao; D. Nithya; B.K. Gupta; B. Kumar; J. Gupta; S. Bhandari; A. Agrawal; M. Shameem; N. Fatima; S. Pala; V. Nongpiur; S. Chatterji; S. Mukherjee; S.K. Shivnitwar; S. Tripathy; P. Lokhande; H. Dandu; A. Gupta; V. Kumar; N. Sharma; R. Vohra; A. Paliwal; M. Pavan Kumar; A. Bikshapathi Rao; N. Kikon; R. Kikon; K. Manohar; Y. Sathyanarayana Raju; A. Madharia; J. Chakravarty; M. Chaubey; R.K. Bandaru; M. Ali Mirza; S. Kataria; P. Sharma; S. Ghosh; A. Hazra
Objectives: This study aims to describe the demographic and clinical profile and ascertain the determinants of outcome among hospitalized coronavirus disease 2019 (COVID-19) adult patients enrolled in the National Clinical Registry for COVID-19 (NCRC). Methods: NCRC is an on-going data collection platform operational in 42 hospitals across India. Data of hospitalized COVID-19 patients enrolled in NCRC between 1st September 2020 to 26th October 2021 were examined. Results: Analysis of 29 509 hospitalized, adult COVID-19 patients [mean (SD) age: 51.1 (16.2) year; male: 18 752 (63.6%)] showed that 15 678 (53.1%) had at least one comorbidity. Among 25 715 (87.1%) symptomatic patients, fever was the commonest symptom (72.3%) followed by shortness of breath (48.9%) and dry cough (45.5%). In-hospital mortality was 14.5% (n = 3957). Adjusted odds of dying were significantly higher in age group ≥60 years, males, with diabetes, chronic kidney diseases, chronic liver disease, malignancy and tuberculosis, presenting with dyspnoea and neurological symptoms. WHO ordinal scale 4 or above at admission carried the highest odds of dying [5.6 (95% CI: 4.6–7.0)]. Patients receiving one [OR: 0.5 (95% CI: 0.4–0.7)] or two doses of anti-SARS CoV-2 vaccine [OR: 0.4 (95% CI: 0.3–0.7)] were protected from in-hospital mortality. Conclusions: WHO ordinal scale at admission is the most important independent predictor for in-hospital death in COVID-19 patients. Anti-SARS-CoV2 vaccination provides significant protection against mortality. © The Author(s) 2022.