Browsing by Author "S. Tripathi"

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A study of bone marrow failure syndrome in children
(Medknow Publications and Media Pvt. Ltd, 2008) V. Gupta; S. Tripathi; T.B. Singh; V. Tilak; B.D. Bhatia
Background: Bone marrow failure syndrome (BMFS), or aplastic anemia, includes peripheral blood single cytopenias, as well as pancytopenia due to inability of the marrow to effectively produce blood cells. Aim: To study the clinico-hematological profile and etiological factors of bone marrow failure syndrome in children. Setting and Design: This prospective study was carried out in the Department of Pediatrics of a university teaching hospital over 36 months. Materials and Methods: Children with pancytopenia (Hb < 10 g/dl, absolute neutrophil count < 1.5 × 109/L, platelet count < 100 × 109/L) and bone marrow cellularity < 25% were included in the study. History of exposure to drugs, socioeconomic status, ethnicity and occupation of father were noted. Bone marrow aspiration; trephine biopsy; Ham test; viral studies for hepatitis A, B and C; and cytogenetic investigations were carried out. Statistical Analysis: Relative risk was estimated by odds ratio (OR) with 95% confidence interval (CI) in matched cases and controls. Results: Of the 53 children studied, 6 (11.3%) were diagnosed as Fanconi anemia. Two cases had features of myelodysplastic syndrome. Forty-five children were labeled as acquired aplastic anemia, of whom one had evidence of hepatitis B infection and two patients (5.8%) had paroxysmal nocturnal hemoglobinuria. Aplastic anemia was more common in children from family with lower socioeconomic status; in Muslims; and where the father's occupation was weaving, dyeing and painting. However, the number was small to make statistically significant conclusions. No correlation could be established with exposure to drugs. Conclusion: Fanconi anemia was responsible for approximately one-tenth of the cases of bone marrow failure syndrome. Majority of the patients had acquired aplastic anemia. Hepatitis B infection was an uncommon cause of acquired aplastic anemia.
A study of clinico-haematological profiles of pancytopenia in children
(2008) V. Gupta; S. Tripathi; V. Tilak; B.D. Bhatia
We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin <10 g/dL, absolute neutrophil count 1.5 × 109/L and platelet count <100 × 109/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5–18 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%. © 2008, SAGE Publications. All rights reserved.
Atmospheric N and P deposition in the Ganges Basin
(Indian Academy of Sciences, 2016) J. Pandey; U. Pandey; A.V. Singh; S. Tripathi; V. Mishra
[No abstract available]
Bayes analysis of a three-parameter pareto distribution via sample based approaches
(2007) S.K. Upadhyay; M. Peshwani; I.A. Javed; S. Tripathi; Rajeev Pandey
This paper considers an important but less explored model, namely the three-parameter Pareto distribution that, besides having applications in many important areas, has been advocated in the context of failure time data analysis. The analysis has been done using both the Gibbs sampler vs. the Metropolis algorithm, and it has been shown that the Metropolis algorithm offers significant improvement over the Gibbs sampler. The extension of the two algorithms for censored situations is also given. For numerical illustration, we have considered both the real and the simulated data sets from the model. In the second part of the study, we illustrate the assumed model on the basis of a real data set using the tool kits of Bayesian predictive simulation ideas. © 2007, Taylor & Francis Group, LLC. All rights reserved.
Bronco T (Shirisadi kasaya), a polyherbal formulation prevents LPS induced septicemia in rats
(Verduci Editore s.r.l, 2022) P. Mishra; R. Pandey; S. Tripathi; S.K. Dubey; Yamini B. Tripathi
OBJECTIVE: Here, Bronco T (BT), a polyherbal formulation developed in 1984 for treating asthma, has been repurposed against septicemia-induced ALI. MATERIALS AND METHODS: Lipopolysaccharides (3 mg/kg BW) were injected intraperitoneally before 24 hours of surgery to assess the cardiorespiratory parameters, blood PaO2/FiO2 and MPO, pulmonary water content and histological changes in the lungs. The pentoxifylline (PTX) (25 mg/kg BW) was used as the positive control and given one hour before LPS. BT was given 3 hours (orally at different doses of 3, 1.5 and 0.75 g/kg BW) before LPS. RESULTS: The LPS treated group showed significant bradypnea, hypotension and bradycardia, through elongated peaks (RR) and (MAP) respectively and finally death after 95 minutes of LPS injection. The PTX and BT (3 g/kg BW) pretreatment significantly prevented these changes (dose-dependent in the BT group). The survival in these groups was maintained up to 190 min after LPS. The Pentoxifylline showed a better response (75%) than Bronco T (72%). In both the treatments, a significant decrease in pulmonary water content and minimal neutrophil infiltration and intact alveoli-capillary membrane was seen in the transverse section (T.S) of the lungs. CONCLUSIONS: Significant improvement was noted in survival time with lesser tissue damage and improved pulmonary function was observed by pre-treating with Bronco T in LPS induced septicemia. © 2022 Verduci Editore s.r.l. All rights reserved.
Delineation of groundwater potential zones, groundwater estimation and recharge potentials from Mahoba district of Uttar Pradesh, India
(Institute for Ionics, 2022) D.S. Gupta; A. Biswas; P. Ghosh; U. Rawat; S. Tripathi
Mahoba district comes under Uttar Pradesh, India, and is a hard rock area overlain by the recent alluvium. Most of the agricultural activities were present in such alluvium. However, they are shallow which were deteriorating with time. The severe scarcity and sudden spreading of groundwater in the region directed us to study the potential groundwater zones. In the current study, groundwater potential zones using multi-criteria evaluation techniques were carried out. Various thematic maps such as landuse/landcover, geomorphology, lithology, soil, slope, lineament, and drainage maps were considered to demarcate potential zones. Approximately 0.7% belongs to ‘very good to good’ groundwater potential zones, 2.4% for ‘moderate to good’, carefully followed by 83% for ‘low to moderate’ groundwater potential zones and roughly around 12%, 0.7%, and 0.9% falls under the ‘very low to low’, ‘nil to very low’, and ‘no potential zones’ zones, respectively. The majority of the district suggests a low to moderate potential groundwater zone. The validation of results was in agreement with the evidence obtained as area under curve (AUC) was calculated to be 85.99%. Groundwater estimation for present and prospects was also carried out and shows that two blocks, namely Panwari and Jaitpur, show a decline in groundwater prospects. The other two blocks, namely Charkhari and Kabrai, also offer a declining trend, but the possibilities are better than the other two. Hence, the results from this study will be beneficial in enhanced groundwork and managing the groundwater resources for present and prospects in the entire district. © 2021, Islamic Azad University (IAU).
Science Requirements and Detector Concepts for the Electron-Ion Collider: EIC Yellow Report
(Elsevier B.V., 2022) R. Abdul Khalek; A. Accardi; J. Adam; D. Adamiak; W. Akers; M. Albaladejo; A. Al-bataineh; M.G. Alexeev; F. Ameli; P. Antonioli; N. Armesto; W.R. Armstrong; M. Arratia; J. Arrington; A. Asaturyan; M. Asai; E.C. Aschenauer; S. Aune; H. Avagyan; C. Ayerbe Gayoso; B. Azmoun; A. Bacchetta; M.D. Baker; F. Barbosa; L. Barion; K.N. Barish; P.C. Barry; M. Battaglieri; A. Bazilevsky; N.K. Behera; F. Benmokhtar; V.V. Berdnikov; J.C. Bernauer; V. Bertone; S. Bhattacharya; C. Bissolotti; D. Boer; M. Boglione; M. Bondì; P. Boora; I. Borsa; F. Bossù; G. Bozzi; J.D. Brandenburg; N. Brei; A. Bressan; W.K. Brooks; S. Bufalino; M.H.S. Bukhari; V. Burkert; N.H. Buttimore; A. Camsonne; A. Celentano; F.G. Celiberto; W. Chang; C. Chatterjee; K. Chen; T. Chetry; T. Chiarusi; Y.-T. Chien; M. Chiosso; X. Chu; E. Chudakov; G. Cicala; E. Cisbani; I.C. Cloet; C. Cocuzza; P.L. Cole; D. Colella; J.L. Collins; M. Constantinou; M. Contalbrigo; G. Contin; R. Corliss; W. Cosyn; A. Courtoy; J. Crafts; R. Cruz-Torres; R.C. Cuevas; U. D'Alesio; S. Dalla Torre; D. Das; S.S. Dasgupta; C. Da Silva; W. Deconinck; M. Defurne; W. DeGraw; K. Dehmelt; A. Del Dotto; F. Delcarro; A. Deshpande; W. Detmold; R. De Vita; M. Diefenthaler; C. Dilks; D.U. Dixit; S. Dulat; A. Dumitru; R. Dupré; J.M. Durham; M.G. Echevarria; L. El Fassi; D. Elia; R. Ent; R. Esha; J.J. Ethier; O. Evdokimov; K.O. Eyser; C. Fanelli; R. Fatemi; S. Fazio; C. Fernandez-Ramirez; M. Finger; D. Fitzgerald; C. Flore; T. Frederico; I. Friščić; S. Fucini; S. Furletov; Y. Furletova; C. Gal; L. Gamberg; H. Gao; P. Garg; D. Gaskell; K. Gates; M.B. Gay Ducati; M. Gericke; G. Gil Da Silveira; F.-X. Girod; D.I. Glazier; K. Gnanvo; V.P. Goncalves; L. Gonella; J.O. Gonzalez Hernandez; Y. Goto; F. Grancagnolo; L.C. Greiner; W. Guryn; V. Guzey; Y. Hatta; M. Hattawy; F. Hauenstein; X. He; T.K. Hemmick; O. Hen; G. Heyes; D.W. Higinbotham; A.N. Hiller Blin; T.J. Hobbs; M. Hohlmann; T. Horn; T.-J. Hou; J. Huang; Q. Huang; G.M. Huber; C.E. Hyde; G. Iakovidis; Y. Ilieva; B.V. Jacak; P.M. Jacobs; M. Jadhav; Z. Janoska; A. Jentsch; T. Jezo; X. Jing; P.G. Jones; K. Joo; S. Joosten; V. Kafka; N. Kalantarians; G. Kalicy; D. Kang; Z.B. Kang; K. Kauder; S.J.D. Kay; C.E. Keppel; J. Kim; A. Kiselev; M. Klasen; S. Klein; H.T. Klest; O. Korchak; A. Kostina; P. Kotko; Y.V. Kovchegov; M. Krelina; S. Kuleshov; S. Kumano; K.S. Kumar; R. Kumar; L. Kumar; K. Kumerički; A. Kusina; K. Kutak; Y.S. Lai; K. Lalwani; T. Lappi; J. Lauret; M. Lavinsky; D. Lawrence; D. Lednicky; C. Lee; K. Lee; S.H. Lee; S. Levorato; H. Li; S. Li; W. Li; X. Li; W.B. Li; T. Ligonzo; H. Liu; M.X. Liu; X. Liu; S. Liuti; N. Liyanage; C. Lorcé; Z. Lu; G. Lucero; N.S. Lukow; E. Lunghi; R. Majka; Y. Makris; I. Mandjavidze; S. Mantry; H. Mäntysaari; F. Marhauser; P. Markowitz; L. Marsicano; A. Mastroserio; V. Mathieu; Y. Mehtar-Tani; W. Melnitchouk; L. Mendez; A. Metz; Z.-E. Meziani; C. Mezrag; M. Mihovilovič; R. Milner; M. Mirazita; H. Mkrtchyan; A. Mkrtchyan; V. Mochalov; V. Moiseev; M.M. Mondal; A. Morreale; D. Morrison; L. Motyka; H. Moutarde; C. Muñoz Camacho; F. Murgia; M.J. Murray; P. Musico; P. Nadel-Turonski; P.M. Nadolsky; J. Nam; P.R. Newman; D. Neyret; D. Nguyen; E.R. Nocera; F. Noferini; F. Noto; A.S. Nunes; V.A. Okorokov; F. Olness; J.D. Osborn; B.S. Page; S. Park; A. Parker; K. Paschke; B. Pasquini; H. Paukkunen; S. Paul; C. Pecar; I.L. Pegg; C. Pellegrino; C. Peng; L. Pentchev; R. Perrino; F. Petriello; R. Petti; A. Pilloni; C. Pinkenburg; B. Pire; C. Pisano; D. Pitonyak; A.A. Poblaguev; T. Polakovic; M. Posik; M. Potekhin; R. Preghenella; S. Preins; A. Prokudin; P. Pujahari; M.L. Purschke; J.R. Pybus; M. Radici; R. Rajput-Ghoshal; P.E. Reimer; M. Rinaldi; F. Ringer; C.D. Roberts; S. Rodini; J. Rojo; D. Romanov; P. Rossi; E. Santopinto; M. Sarsour; R. Sassot; N. Sato; B. Schenke; W.B. Schmidke; I. Schmidt; A. Schmidt; B. Schmookler; G. Schnell; P. Schweitzer; J. Schwiening; I. Scimemi; S. Scopetta; J. Segovia; R. Seidl; S. Sekula; K. Semenov-Tian-Shanskiy; D.Y. Shao; N. Sherrill; E. Sichtermann; M. Siddikov; A. Signori; B.K. Singh; S. Širca; K. Slifer; W. Slominski; D. Sokhan; W.E. Sondheim; Y. Song; O. Soto; H. Spiesberger; A.M. Stasto; P. Stepanov; G. Sterman; J.R. Stevens; I.W. Stewart; I. Strakovsky; M. Strikman; M. Sturm; M.L. Stutzman; M. Sullivan; B. Surrow; P. Svihra; S. Syritsyn; A. Szczepaniak; P. Sznajder; H. Szumila-Vance; L. Szymanowski; A.S. Tadepalli; J.D. Tapia Takaki; G.F. Tassielli; J. Terry; F. Tessarotto; K. Tezgin; L. Tomasek; F. Torales Acosta; P. Tribedy; A. Tricoli; Triloki; S. Tripathi; R.L. Trotta; O.D. Tsai; Z. Tu; C. Tuvè; T. Ullrich; M. Ungaro; G.M. Urciuoli; A. Valentini; P. Vancura; M. Vandenbroucke; C. Van Hulse; G. Varner; R. Venugopalan; I. Vitev; A. Vladimirov; G. Volpe; A. Vossen; E. Voutier; J. Wagner; S. Wallon; H. Wang; Q. Wang; X. Wang; S.Y. Wei; C. Weiss; T. Wenaus; H. Wennlöf; N. Wickramaarachchi; A. Wikramanayake; D. Winney; C.P. Wong; C. Woody; L. Xia; B.W. Xiao; J. Xie; H. Xing; Q.H. Xu; J. Zhang; S. Zhang; Z. Zhang; Z.W. Zhao; Y.X. Zhao; L. Zheng; Y. Zhou; P. Zurita
This report describes the physics case, the resulting detector requirements, and the evolving detector concepts for the experimental program at the Electron-Ion Collider (EIC). The EIC will be a powerful new high-luminosity facility in the United States with the capability to collide high-energy electron beams with high-energy proton and ion beams, providing access to those regions in the nucleon and nuclei where their structure is dominated by gluons. Moreover, polarized beams in the EIC will give unprecedented access to the spatial and spin structure of the proton, neutron, and light ions. The studies leading to this document were commissioned and organized by the EIC User Group with the objective of advancing the state and detail of the physics program and developing detector concepts that meet the emerging requirements in preparation for the realization of the EIC. The effort aims to provide the basis for further development of concepts for experimental equipment best suited for the science needs, including the importance of two complementary detectors and interaction regions. This report consists of three volumes. Volume I is an executive summary of our findings and developed concepts. In Volume II we describe studies of a wide range of physics measurements and the emerging requirements on detector acceptance and performance. Volume III discusses general-purpose detector concepts and the underlying technologies to meet the physics requirements. These considerations will form the basis for a world-class experimental program that aims to increase our understanding of the fundamental structure of all visible matter. © 2022 Elsevier B.V.