Browsing by Author "S.K. Agarwal"

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A histochemical study of the epidermis of the climbing perch, Anabas testudineus (anabantidae, pisces)
(1980) S.K. Agarwal; T.K. Banerjee; A.K. Mittal
A histochemical investigation has been made to localize and characterize various lipid, protein, carbohydrate and enzyme constituents present within the different cell types of the epidermis of Anabas testudineus. The polygonal cells contain glycogen, the amount of which gradually increases as the cells move towards the surface until they reach the most superficial layer where the amount of glycogen slightly decreases indicating the metabolically active state of these cells. The basal cells, which frequently undergo cell proliferation, contain no glycogen. The polygonal cells give strong reactions for SDH, alkaline phosphatase, cholesterol esters and nonsulphated acid mucopolysaccharides, moderate reactions for acidic lipids, phospholipids and free cholesterol and weak reactions for neutral mucopolysaccharides, protein bound NH2 groups, mucoprotein, tyrosine, tryptophan and cysteine bound sulphydryl groups. These cells in the outermost layer give stronger reactions for acidic lipids, phospholipids and cholesterol esters and weaker reactions for SDH and alkaline phosphatase activities. The above findings reveal that the polygonal cells remain metabolically active throughout the epidermis. The mucus cells are numerous and secrete a mixture of neutral mucopolysaccharides, sulphated acid mucopolysaccharides and nonsulphated acid mucopolysaccharides. The contents of the sacciform granulated cells are mainly proteins. A thick coat of slime over the body surface containing mucopolysaccharides, lipids and proteins is important in keeping the skin moist and may facilitate the survival of the fish while it is on land. The melanophores in the epidermis play an important role in preventing the colonization by parasites, fungi and bacteria over the body surface, and act as macrophages.
Allergic bronchopulmonary aspergillosis
(1982) S.K. Agarwal; D.C. Roy
[No abstract available]
Electrocardiographic abnormalities in tropical pulmonary eosinophilia.
(1990) S.K. Agarwal; D.C. Roy; A. Johri
A 12 lead electrocardiogram in 70 patients with tropical pulmonary eosinophilia showed abnormalities 28.57%. ECG changes observed were right axis deviation (10%), 'P' pulmonale (10%), clockwise rotation (5.7%), right ventricular hypertrophy (1.4%), partial RBBB (2.8%), first degree A-V block (1.4%) and ST-T changes (1.4%). All ECG changes reverted back to normal after diethyl carbamzine therapy in the dose of 10 mg/kg body weight for a total duration of 14 days.
Fine structure and histochemistry of the epidermis of the fish Monopterus cuchia
(1980) A.K. Mittal; M. Whitear; S.K. Agarwal
An attempt is made to correlate fine structure with the histochemical reactions of the epidermis in the synbranchiform fish Monopterus cuchia. Three sources of mucus are identified. Superficial epithelial cells produce weakly acidic glycoprotein which is secreted at the surface as the external mucous layer or cuticle. Numerous large unicellular mucous glands have a secretion which is strongly acidic and sulphated, although the basal and peripheral parts of these cells, which contain most of the rough endoplasmic reticulum, react strongly for neutral glycoprotein; Golgi cisternae appear to be involved in a change of histochemical reaction from neutral to strongly acidic as the secretion is formed. A second, slender, type of mucous gland cell, not previously reported, gives a weaker reaction for sulphated acidic glycoprotein and has cytoplasm with numerous Golgi cisternae and free ribosomes, producing electron–dense secreted drops. Sacciform cells, with a protein–aceous secretion, have a characteristic fine structure with membranous “bubbles” at the surface of the cytoplasm. Ionocytes, sensor) cells and intrusive leucocytes have been identified in the epidermis. Copyright © 1980, Wiley Blackwell. All rights reserved
Histochemical localization of alkaline phosphatase, acid phosphatase, and succinic dehydrogenase activities in the epidermis of the freshwater teleost, Amphipnous cuchia (Hamilton) (Symbranchiformes, Pisces)
(1976) T.K. Banerjee; S.K. Agarwal; A.K. Rai; A.K. Mittal
[No abstract available]
Histochemistry of the unicellular glands in relation to their physiological significance in the epidermis of Monopterus cuchia (Synbranchiformes, Pisces)
(1977) A.K. Mittal; S.K. Agarwal
The cytochemical nature of the secretory contents of the unicellular glands—the mucous cells and the sacciform granulated cells in the epidermis of Monopterus cuchia has been described in order to understand their physiological significance. The mucous cells secrete mainly the acid mucopolysaccharides and mucoproteins in addition to small amounts of phospholipids. The secretory contents of the sacciform granulated cells are proteinaceous in nature and give strong reactions for elastin, tryptophan and tryosine. High amounts of cholesterol and small amounts of phospholipids and acid mucopolysaccharides are also identified in these sacciform granulated cells. Phospholipids, mucoproteins and elastin could well increase the viscosity of mucopolysaccharides retaining the slimy secretions on the surface for relatively longer periods. The retention of mucopolysaccharides and elastin on the surface for longer periods that can bind large amounts of water has been correlated to keep the skin moist, facilitating the cutaneous respiration and preventing the fish from desiccation when it is on land. The role of elastin in protecting the fish from various chemical attacks and mechanical stresses is also discussed. Tryptophan secreted by sacciform granulated cells may have the immunological role facilitating the antibody transfer across the epidermis. Copyright © 1977, Wiley Blackwell. All rights reserved
Impact of sintering temperature on room temperature magneto-resistive and magneto-caloric properties of Pr2/3Sr1/3MnO3
(Elsevier Ltd, 2013) Ramesh Chandra Bhatt; Shiva Kumar Singh; P.C. Srivastava; S.K. Agarwal; V.P.S. Awana
Magneto-resistive and magneto-caloric properties of polycrystalline Pr 2/3Sr1/3MnO3 have been studied as a function of sintering temperature (Ts) between 1260 and 1450 °C. Reitveld refinement of their X-ray diffraction (XRD) patterns confirms their single phase crystalline structure with orthorhombic Pbnm space group. The point of maximum value of temperature coefficient of resistance (TCRmax) and Curie temperature (Tc) decreased slightly with Ts. Magneto-resistance (MR) and magnetic entropy (DSM) increased markedly with sintering temperature. This could be attributed to the observed sharpness of both the magnetic and resistive transitions due to better grain connectivity. Optimum results are obtained for the sample with Ts = 1400 °C. MR at Tc of the same is found to be as large as 32% at 1T and 58% at 5T magnetic fields. The maximum entropy change (DSMmax) near its Tc is 2.3 J kg-1 K-1 and 7.8 J kg--1 K-1 upon 1T and 5T fields change respectively. These characteristics [MR (32% 1T, 58% 5T) and reasonable change in magnetic entropy (7.8 J kg-1 K-1, 5T)] generate possibility that the optimized compound can be used as a potential magnetic refrigerant close to room temperature. © 2013 Elsevier B.V. All rights reserved.
Intermittent chemotherapy in retreatment cases of pulmonary tuberculosis
(1985) S.K. Agarwal; D.C. Roy; S.C. Matah
[No abstract available]
Lipids in the skin of a cat-fish Heteropneustes fossilis (Bloch) (Heteropneustidae, Pisces) - A histochemical investigation
(Springer-Verlag, 1976) A.K. Mittal; A.K. Rai; T.K. Banerjee; S.K. Agarwal
Localization and characterization of different lipids in the cellular constituents of the skin of Heteropneustes fossilis has been made using several histochemical techniques. High contents of cholesterol, its esters and phospholipids have been correlated with the metabolically active state of the basal cells undergoing cell proliferation and differentiation. The polygonal cells in the outermost layer of the epidermis, though rich in phospholipid contain small amounts of cholesterol and its esters. This has been correlated with the metabolically less active state of these cells. Neutral lipids and phospholipids in the polygonal cells of the outermost layer may contribute to the contents of surface slime and act as an efficient barrier for the penetration of water through the skin. The deposits of neutral lipids in the subcutis may provide energy during the period of fasting, act as a barrier for water diffusion through the skin and serve as shock absorbing pads protecting the fish from mechanical injury. © 1976 Springer-Verlag.
Magneto-resistance, magneto-caloric and bolometric properties in Pr2/3Sr1/3MnO3:PdO composites near room temperature
(Institute of Physics Publishing, 2014) Ramesh Chandra Bhatt; P.C. Srivastava; V.P.S. Awana; H. Kishan; S.K. Agarwal
Temperature coefficient of resistance (TCR), magneto-resistance (MR) and magneto-caloric properties of polycrystalline pristine Pr2/3Sr1/3MnO3 (PSMO) and its composites with PdO (10-30 mole %) (PSMO:Pd) have been studied. Rietveld refinement of their x-ray diffraction (XRD) patterns confirms their single phase crystalline structure with orthorhombic Pbnm space group and Pd appears in pure metallic phase. Of the various composites investigated, PSMO: Pd30 composite exhibits significant TCR of 9.7%K-1 (at 281 K) and low field MR value of 33.5% (H= 1 T). Magnetic entropy change (ΔSM) has been found to be 3.5 J kg-1K-1 (1 T), 6.3 J kg-1K-1 (2 T) and 8.7 J kg-1K-1 (3 T) at 283K for PSMO:Pd10 sample which show a decreasing trend with increasing Pd content. Present investigations reveal excellent characteristics for bolometric, magnetic sensing and magnetic refrigerating applications near room temperature by PSMO:Pd composites. © 2014 IOP Publishing Ltd.
Observance of improved magneto-resistance and magnetic entropy change in La0.7(Ca0.2Sr0.1)MnO3:Pd composite
(Springer New York LLC, 2014) Ramesh Chandra Bhatt; P.C. Srivastava; S.K. Agarwal; V.P.S. Awana
Magneto-resistive and magneto-caloric properties of polycrystalline La 0.7(Ca0.2Sr0.1)MnO3 (LCSMO) and La0.7(Ca0.2Sr0.1)MnO3:10 %PdO (LCSMO:Pd10) composites sintered at 1400 °C have been investigated. Rietveld refinement of their X-ray diffraction (XRD) patterns confirms the single-phase crystalline structure with orthorhombic Pbnm space group, showing no significant change in their lattice parameters with Pd addition. Disappearance of the low temperature resistivity hump in the Pd composite has been attributed to the suppression of the grain boundary effect and the conducting channels due to the presence of metallic Pd. While the Curie temperature T c remained nearly unchanged, the peak value of the temperature coefficient of resistance (TCR) increased in the composite. TCRMAX increased to 6.4 % (at 308 K) in the composite from 2 % (at 305 K) for the pristine LCSMO. Magneto-resistance (MR) and magnetic entropy change (ΔS M ) also increased markedly in the composite material. This could be ascribed to the observed sharpness of both the magnetic and resistive transitions resulting from better grain connectivity. Maximum MR of 12.9 % (1 T) and 19.6 % (2 T) has been observed close to its T c (309 K) in the pristine LCSMO. These values increased to 24.1 % (1 T) and 33.9 % (2 T) with the addition of PdO. The maximum values of |ΔS M | are found to be 4.4, 8.2 and 11.7 J∈kg-1∈K-1 at field values of 1, 2 and 3 T, respectively, for LCSMO:Pd10 composite, which are far better than those reported for LCSMO:Ag10 composite. © 2013 Springer Science+Business Media New York.
Once a week short-term tuberculosis therapy
(1983) S.K. Agarwal; D.C. Roy; D. Pal
Seventy patients were used as subjects for the present study from among those in the Tuberculosis Chemotherapy Unit, University Health Centre, Banaras Hindu University and were randomly designated to either the five month intermittent regimen or the twelve month standard regimen. Fifteen patients were excluded from the main analysis either due to drug toxicity or non-compliance. There was a significant difference in drug default in the short-term regimen (3.3%) in comparison to the standard regimen (17.5%). Radiological improvement was observed following three months (P<0.005). After a period of five months (P<0.001) statistically significant differences were also observed. Bacteriological conversion occurred faster in the rifampicin containing regimen. Three (10%) patients on rifampicin showed 'flu-like' symptoms, while four (13.33%) exhibited muscular weakness. Two (5%) patients on thiacetazone suffered from exfoliative dermatitis, and streptomycin toxicity occurred in five (7.15) patients. A twelve month post-study revealed a relapse in 3.7% of the patients in the short-term regimen and 7.14% of those in the standard regimen.
Physiological adaptation in relation to hyperosmotic stress in the epidermis of a fresh-water teleost Barbus sophor (cypriniformes, cyprinidae): A histochemical study
(1979) S.K. Agarwal; T.K. Banerjee; A.K. Mittal
[No abstract available]
Protein and carbohydrate histochemistry in relation to the keratinization in the epidermis of Barbus sophor (Cyprinidae, Pisces)
(1976) A.K. Mittal; S.K. Agarwal; T.K. Banerjee
The distribution of protein and carbohydrate constituents in the epidermis of Barbus sophor is described in order to give a better understanding of its cellular organization and physiology. Various cytochemical techniques show the keratinized nature of the outer free margins of the polygonal cells in the most‐superficial layer. These contain appreciable amounts of cysteine bound sulphydryl groups, basic proteins, protein bound NH2 groups, ribonucleic acid and calcium and give a strong Papanicolaou's reaction. Absence of cystine bound disulphide groups suggests that the cornified layer in B. sophor is probably mechanically weak as adjacent keratin chains remain unbonded. The polygonal cells showing keratinization at the outer free margins remain metabolically active and are not sloughed off at the surface. This is in contrast to the keratinized epidermis of other teleosts so far reported in which the keratinized cells are dead and are sloughed off at the surface. In addition to keratinization the polygonal cells undergo mucogenesis synthesizing sulphated acid mucopolysaccharides. The presence of eosinophilic granular cells in the epidermis is interesting. The possible role of these cells in the protection of the epidermis has been discussed. The epidermis on the inner surface of the scale is very thin so it may not have much protective significance in these areas. Copyright © 1976, Wiley Blackwell. All rights reserved
Pulmonary alveolar microlithiasis.
(1991) S.K. Agarwal; D.C. Roy; A. Johri
[No abstract available]
Revised national tuberculosis control programme
(1997) S.K. Agarwal
[No abstract available]
Supervised intermittent therapy in tuberculosis
(1997) S.K. Agarwal
[No abstract available]